List of works - Saghir Akhtar

Activation of EGFR/ERBB2 via Pathways Involving ERK1/2, P38 MAPK, AKT and FOXO Enhances Recovery of Diabetic Hearts from Ischemia-Reperfusion Injury ⬇️

scientific article published on June 13, 2012

Angiotensin-(1-7) Downregulates Diabetes-Induced cGMP Phosphodiesterase Activation in Rat Corpus Cavernosum.

scientific article published on 19 February 2017

Angiotensin‐(1–7) inhibits allergic inflammation, via the MAS1 receptor, through suppression of ERK1/2‐ and NF‐κB‐dependent pathways ⬇️

scientific article published on July 1, 2012

Antisense Technology: Selection and Delivery of Optimally Acting Antisense Oligonucleotides ⬇️

scientific article published on 01 January 1998

Cationic nanosystems for the delivery of small interfering ribonucleic acid therapeutics: a focus on toxicogenomics ⬇️

scientific article published on 07 October 2010

Cellular Uptake Properties of a 2‵-Amino/2‵-O-Methyl-Modified Chimeric Hammerhead Ribozyme Targeted to the Epidermal Growth Factor Receptor mRNA ⬇️

scientific article published on August 1, 1997

Chronic treatment with Ang-(1-7) reverses abnormal reactivity in the corpus cavernosum and normalizes diabetes-induced changes in the protein levels of ACE, ACE2, ROCK1, ROCK2 and omega-hydroxylase in a rat model of type 1 diabetes

scientific article

Development of a Sustained-Release Biodegradable Polymer Delivery System for Site-Specific Delivery of Oligonucleotides: Characterization of P(LA-GA) Copolymer MicrospheresIn Vitro ⬇️

scientific article published on January 1, 1998

In honour of Professor Jindřich (Henry) Kopeček, Recipient of the Journal of Drug Targeting’s Life-Time Achievement Award for 2011 ⬇️

scientific article published on November 3, 2011

Interaction of oligonucleotide-conjugates with the dipeptide transporter system in CACO-2 cells ⬇️

scientific article published on May 9, 1997

Liposomes as a drug delivery system for antisense oligonucleotides

scientific article published on January 1, 1992

Molecular DIY with hairpins and hammerheads ⬇️

scientific article published on 01 April 1995

Nanotoxicology of Dendrimers in the Mammalian Heart: ex vivo and in vivo Administration of G6 PAMAM Nanoparticles Impairs Recovery of Cardiac Function Following Ischemia-Reperfusion Injury

scientific article published on 19 June 2020

On the nanotoxicity of PAMAM dendrimers: Superfect® stimulates the EGFR–ERK1/2 signal transduction pathway via an oxidative stress-dependent mechanism in HEK 293 cells ⬇️

scientific article published on March 26, 2013

Sequence and chemistry requirements for a novel aptameric oligonucleotide inhibitor of EGF receptor tyrosine kinase activity

scientific article published in June 2002

Synthetic 2′-O-Mrthyl-Modified Hammerhead Ribozymes Targeted to the RNA Component of Telomerase as Sequence-Specific Inhibitors of Telomerase Activity ⬇️

scientific article published on August 1, 1998

The role of epidermal growth factor receptor in diabetes-induced cardiac dysfunction ⬇️

scientific article published on January 26, 2013

List of works by Saghir Akhtar