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List of works by Karl Tryggvason

A novel podocyte gene, semaphorin 3G, protects glomerular podocyte from lipopolysaccharide-induced inflammation

scientific article published on 16 May 2016

A reverse genetic screen in the zebrafish identifies crb2b as a regulator of the glomerular filtration barrier

scientific article published on 23 April 2009

Altered ultrastructural distribution of nephrin in minimal change nephrotic syndrome

scientific article

Antibodies blocking adhesion and matrix binding domains of laminin-332 inhibit tumor growth and metastasis in vivo

scientific article

Association of genetic variants at 3q22 with nephropathy in patients with type 1 diabetes mellitus

scientific article published on 11 December 2008

Association testing of previously reported variants in a large case-control meta-analysis of diabetic nephropathy

scientific article

Chromosome 2q31.1 associates with ESRD in women with type 1 diabetes

scientific article

Clonal culturing of human embryonic stem cells on laminin-521/E-cadherin matrix in defined and xeno-free environment

scientific article published on January 2014

Correction: Schip1 Is a Novel Podocyte Foot Process Protein that Mediates Actin Cytoskeleton Rearrangements and Forms a Complex with Nherf2 and Ezrin

scientific article published on 12 May 2015

Defective prelamin A processing and muscular and adipocyte alterations in Zmpste24 metalloproteinase-deficient mice

scientific article published in April 2002

Deficiency in crumbs homolog 2 (Crb2) affects gastrulation and results in embryonic lethality in mice ⬇️

scientific article published on December 1, 2011

Dendrin expression in glomerulogenesis and in human minimal change nephrotic syndrome

scientific article

Expression and subcellular distribution of novel glomerulus-associated proteins dendrin, ehd3, sh2d4a, plekhh2, and 2310066E14Rik

scientific journal article

Genome-wide association study of urinary albumin excretion rate in patients with type 1 diabetes

article by Niina Sandholm et al published 5 March 2014 in Diabetologia

Glcci1 deficiency leads to proteinuria

scientific article published on 23 September 2011

Glomerular Podocytes Express Type 1 Adenylate Cyclase: Inactivation Results in Susceptibility to Proteinuria ⬇️

scientific article published on December 24, 2010

Knockdown of Tmem234 in zebrafish results in proteinuria

scientific article published on 16 September 2015

Large-scale identification of genes implicated in kidney glomerulus development and function

scientific article

Lmx1b and FoxC combinatorially regulate podocin expression in podocytes

scientific article published on 22 May 2014

Neph1 is reduced in primary focal segmental glomerulosclerosis, minimal change nephrotic syndrome, and corresponding experimental animal models of adriamycin-induced nephropathy and puromycin aminonucleoside nephrosis

scientific article published on 19 September 2014

Neuronal proteins are novel components of podocyte major processes and their expression in glomerular crescents supports their role in crescent formation

scientific article published on 22 August 2012

Novel genetic susceptibility loci for diabetic end-stage renal disease identified through robust naive Bayes classification

scientific article published on 29 May 2014

Pdlim2 is a novel actin-regulating protein of podocyte foot processes

scientific article

Plekhh2, a novel podocyte protein downregulated in human focal segmental glomerulosclerosis, is involved in matrix adhesion and actin dynamics

scientific article

Podocin-green fluorescence protein allows visualization and functional analysis of podocytes

scientific article

Rhophilin-1 is a key regulator of the podocyte cytoskeleton and is essential for glomerular filtration

scientific article

Schip1 is a novel podocyte foot process protein that mediates actin cytoskeleton rearrangements and forms a complex with Nherf2 and ezrin

scientific article published on 25 March 2015

The glomerular transcriptome and a predicted protein-protein interaction network

scientific article

Wtip- and gadd45a-interacting protein dendrin is not crucial for the development or maintenance of the glomerular filtration barrier

scientific article

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