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List of works by Fredrik R. Zetterberg

3-Substituted 1-Naphthamidomethyl-C-galactosyls Interact with Two Unique Sub-sites for High-Affinity and High-Selectivity Inhibition of Galectin-3

scientific article published on 12 December 2019

5-alkyl-1,3-oxazole derivatives of 6-amino-nicotinic acids as alkyl ester bioisosteres are antagonists of the P2Y12 receptor

scientific article

A novel series of piperazinyl-pyridine ureas as antagonists of the purinergic P2Y12 receptor

scientific article published on 30 March 2011

Aminopyrimidine-galactose hybrids are highly selective galectin-3 inhibitors

scientific article published on 13 May 2019

An orally active galectin-3 antagonist inhibits lung adenocarcinoma growth and augments response to PD-L1 blockade

scientific article published on 23 January 2019

Defining the mechanism of galectin-3–mediated TGF-β1 activation and its role in lung fibrosis

scientific article published in 2024

Evaluating the affinity and kinetics of small molecule glycomimetics for human and mouse galectin-3 using surface plasmon resonance

scientific article published in 2023

Extracellular and intracellular small-molecule galectin-3 inhibitors

Human trophoblast requires galectin-3 for cell migration and invasion

scientific article published in Scientific Reports

In Vivo Veritas: 18F-Radiolabeled Glycomimetics Allow Insights into the Pharmacological Fate of Galectin-3 Inhibitors

scientific article published on 03 January 2020

Lead optimization of ethyl 6-aminonicotinate acyl sulfonamides as antagonists of the P2Y12 receptor. separation of the antithrombotic effect and bleeding for candidate drug AZD1283.

scientific article published on 29 August 2013

Monosaccharide Derivatives with Low-Nanomolar Lectin Affinity and High Selectivity Based on Combined Fluorine-Amide, Phenyl-Arginine, Sulfur-π, and Halogen Bond Interactions.

scientific article

Optimization of ketone-based P2Y(12) receptor antagonists as antithrombotic agents: pharmacodynamics and receptor kinetics considerations.

scientific article published on 12 April 2014

State of affairs: Design and structure-activity relationships of reversible P2Y12 receptor antagonists.

scientific article published on 13 April 2016

Synthesis, structure-property relationships and pharmacokinetic evaluation of ethyl 6-aminonicotinate sulfonylureas as antagonists of the P2Y₁₂ receptor.

scientific article

Systematic Tuning of Fluoro-galectin-3 Interactions Provides Thiodigalactoside Derivatives with Single-Digit nM Affinity and High Selectivity

scientific article published on 28 December 2017

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