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List of works by Michael A Resnick

A SNP in the flt-1 promoter integrates the VEGF system into the p53 transcriptional network

scholarly article

A double-strand break within a yeast artificial chromosome (YAC) containing human DNA can result in YAC loss, deletion or cell lethality

scientific article published on August 1996

A model system to assess the integrity of mammalian YACs during transformation and propagation in yeast

scientific article published on 01 May 1994

A multistep genomic screen identifies new genes required for repair of DNA double-strand breaks in Saccharomyces cerevisiae.

scientific article

A novel role in DNA metabolism for the binding of Fen1/Rad27 to PCNA and implications for genetic risk.

scientific article

A photoreactivationless mutant of Saccharomyces cerevisiae ⬇️

scientific article published on 01 April 1969

A regulatory loop composed of RAP80-HDM2-p53 provides RAP80-enhanced p53 degradation by HDM2 in response to DNA damage.

scientific article published on 11 May 2009

A single-strand specific lesion drives MMS-induced hyper-mutability at a double-strand break in yeast ⬇️

scientific article published on July 21, 2010

Acetone, methyl ethyl ketone, ethyl acetate, acetonitrile and other polar aprotic solvents are strong inducers of aneuploidy in Saccharomyces cerevisiae

scientific article published on 01 May 1985

Alkylation base damage is converted into repairable double-strand breaks and complex intermediates in G2 cells lacking AP endonuclease.

scientific article

Altered replication and inverted repeats induce mismatch repair-independent recombination between highly diverged DNAs in yeast.

scientific article published on February 1997

Apn1 and Apn2 endonucleases prevent accumulation of repair-associated DNA breaks in budding yeast as revealed by direct chromosomal analysis.

scientific article published on 11 February 2008

Aprotic polar solvents that affect porcine brain tubulin aggregation in vitro induce aneuploidy in yeast cells growing at low temperatures

scientific article published on 01 October 1988

Base damage within single-strand DNA underlies in vivo hypermutability induced by a ubiquitous environmental agent

scientific article

Biased distribution of inverted and direct Alus in the human genome: implications for insertion, exclusion, and genome stability.

scientific article published on January 2001

Blunt-ended DNA double-strand breaks induced by endonucleases PvuII and EcoRV are poor substrates for repair in Saccharomyces cerevisiae.

scientific article

Break-induced replication is a source of mutation clusters underlying kataegis

scientific article

Cadmium is a mutagen that acts by inhibiting mismatch repair.

scientific article published on July 2003

Cell-cycle-specific repair of DNA double strand breaks in Saccharomyces cerevisiae

scientific article published on 01 June 1980

Changes in DNA during meiosis in a repair-deficient mutant (rad 52) of yeast

scientific article published on 01 May 1981

Changes in the chromosomal DNA of yeast during meiosis in repair mutants and the possible role of a deoxyribonuclease

scientific article published on 01 January 1984

Characterizing resection at random and unique chromosome double-strand breaks and telomere ends.

scientific article published on January 2011

Chromosomal aberrations and sister chromatid exchange tests in Chinese hamster ovary cells in vitro. IV. Results with 15 chemicals

scientific article published on 01 January 1989

Chromosome aberration and sister chromatid exchange test results with 42 chemicals.

scientific article published on January 1990

Chromosome aberration and sister chromatid exchange tests in Chinese hamster ovary cells in vitro: II. Results with 20 chemicals

scientific article published on 01 January 1989

Clustered mutations in yeast and in human cancers can arise from damaged long single-strand DNA regions.

scientific article

Cohesin Is limiting for the suppression of DNA damage-induced recombination between homologous chromosomes

scientific article

Comparative evaluation of genetic toxicity patterns of carcinogens and noncarcinogens: strategies for predictive use of short-term assays.

scientific article

Components of the Genetic Repair Mechanism are not confined to the Nucleus

scientific article published in Nature

DNA polymerases, deoxyribonucleases, and recombination during meiosis in Saccharomyces cerevisiae

scientific article published on December 1984

Damage-induced localized hypermutability.

scientific article

Destabilization of Yeast Micro- and Minisatellite DNA Sequences by Mutations Affecting a Nuclease Involved in Okazaki Fragment Processing (rad27) and DNA Polymerase δ (pol3-t) ⬇️

scientific article published on May 1, 1998

Differential effects of poly(ADP-ribose) polymerase inhibition on DNA break repair in human cells are revealed with Epstein-Barr virus

scientific article published on 9 April 2012

Differential transactivation by the p53 transcription factor is highly dependent on p53 level and promoter target sequence.

scientific article

Direct Cloning of Human 10q25 Neocentromere DNA Using Transformation-Associated Recombination (TAR) in Yeast ⬇️

scientific article published on February 1, 1998

Divergent evolution of human p53 binding sites: cell cycle versus apoptosis

scientific article (publication date: July 2007)

Dominant-negative features of mutant TP53 in germline carriers have limited impact on cancer outcomes.

scientific article

ETV7-Mediated DNAJC15 Repression Leads to Doxorubicin Resistance in Breast Cancer Cells

scientific article published on 17 July 2018

Effect of amino acid substitutions in the rad50 ATP binding domain on DNA double strand break repair in yeast

scientific article

Fidelity of DNA polymerase epsilon holoenzyme from budding yeast Saccharomyces cerevisiae

scientific article published on 17 July 2002

Flexibility of eukaryotic Okazaki fragment maturation through regulated strand displacement synthesis

scientific article published on 16 October 2008

Functional analysis of human FEN1 in Saccharomyces cerevisiae and its role in genome stability

scientific article (publication date: November 1999)

Functional copies of a human gene can be directly isolated by transformation-associated recombination cloning with a small 3' end target sequence.

scientific article

Functional dissection of sequence-specific NKX2-5 DNA binding domain mutations associated with human heart septation defects using a yeast-based system.

scientific article

Functional diversity in the gene network controlled by the master regulator p53 in humans.

scientific article

Functionally distinct polymorphic sequences in the human genome that are targets for p53 transactivation.

scientific article

Genes required for ionizing radiation resistance in yeast

scientific article published in December 2001

Genome-wide model for the normal eukaryotic DNA replication fork.

scientific article

Homologous recombination rescues ssDNA gaps generated by nucleotide excision repair and reduced translesion DNA synthesis in yeast G2 cells.

scientific article published on 15 July 2013

Hypermutability of damaged single-strand DNA formed at double-strand breaks and uncapped telomeres in yeast Saccharomyces cerevisiae.

scientific article

Hypermutability of homonucleotide runs in mismatch repair and DNA polymerase proofreading yeast mutants.

scientific article published on May 1997

Impact of mitochondria on nuclear genome stability.

scientific article

Increased LOH due to Defective Sister Chromatid Cohesion Is due Primarily to Chromosomal Aneuploidy and not Recombination.

scientific article published on 5 October 2017

Induction of mutations in Saccharomyces cerevisiae by ultraviolet light ⬇️

scientific article published on 01 May 1969

Inhibition of DNA double-strand break repair by the Ku heterodimer in mrx mutants of Saccharomyces cerevisiae.

scientific article published on 18 November 2008

Interactions between the tumor suppressor p53 and immune responses.

scientific article published on January 2013

Inverted DNA repeats: a source of eukaryotic genomic instability

scientific article published on September 1993

Lethality induced by a single site-specific double-strand break in a dispensable yeast plasmid

scientific article

Ligand dependent restoration of human TLR3 signaling and death in p53 mutant cells.

scientific article published on 11 August 2016

Low-level p53 expression changes transactivation rules and reveals superactivating sequences

scientific article

Molecular recombination and the repair of DNA double-strand breaks in CHO cells ⬇️

scientific article published on July 11, 1979

Mutant TP53 posttranslational modifications: challenges and opportunities.

scientific article

Mutator phenotypes of yeast strains heterozygous for mutations in the MSH2 gene.

scientific article

Noncanonical DNA motifs as transactivation targets by wild type and mutant p53

scientific article

Nuclear DNA Synthesis in Yeast and the Effect of Irradiation ⬇️

scientific article published on April 1, 1977

Okazaki fragment maturation in yeast. II. Cooperation between the polymerase and 3'-5'-exonuclease activities of Pol delta in the creation of a ligatable nick

scientific article (publication date: 17 January 2003)

Prediction of chemical carcinogenicity in rodents from in vitro genetic toxicity assays.

scientific article published in May 1987

Probing the functional impact of sequence variation on p53-DNA interactions using a novel microsphere assay for protein-DNA binding with human cell extracts

scientific article published on 08 May 2009

Quantitative Analysis of NF-κB Transactivation Specificity Using a Yeast-Based Functional Assay

scientific article

RAD50 is required for efficient initiation of resection and recombinational repair at random, gamma-induced double-strand break ends

scientific article published on 18 September 2009

RAD53 is limiting in double-strand break repair and in protection against toxicity associated with ribonucleotide reductase inhibition

scientific article published on 23 January 2012

RAP80 Is Critical in Maintaining Genomic Stability and Suppressing Tumor Development ⬇️

scientific article published on August 15, 2012

Recombination during transformation as a source of chimeric mammalian artificial chromosomes in yeast (YACs)

scientific article published on October 1994

Recombinational repair of radiation-induced double-strand breaks occurs in the absence of extensive resection.

scientific article published on 25 October 2015

Reduced replication: a call to ARMS.

scientific article

Reduction in frataxin causes progressive accumulation of mitochondrial damage.

scientific article published on 21 October 2003

Repeat expansion--all in a flap?

scientific article published on 01 June 1997

Replication slippage between distant short repeats in Saccharomyces cerevisiae depends on the direction of replication and the RAD50 and RAD52 genes.

scientific article published on October 1995

Requirement for end-joining and checkpoint functions, but not RAD52-mediated recombination, after EcoRI endonuclease cleavage of Saccharomyces cerevisiae DNA

scientific article

Revealing a human p53 universe

scientific article published on 01 September 2018

Role of the nuclease activity of Saccharomyces cerevisiae Mre11 in repair of DNA double-strand breaks in mitotic cells.

scientific article

Separation of spores from diploid cells of yeast by stable-flow free-boundary electrophoresis

scientific article

Similar responses to ionizing radiation of fungal and vertebrate cells and the importance of DNA double-strand breaks ⬇️

scientific article published on 01 April 1978

Specific cloning of human DNA as yeast artificial chromosomes by transformation-associated recombination

scientific article

Specific isolation of human rDNA genes by TAR cloning

scientific article published on 01 September 1997

Sunlight-induced killing in Saccharomyces cerevisiae

scientific article published on 01 April 1970

Suppression of allelic recombination and aneuploidy by cohesin is independent of Chk1 in Saccharomyces cerevisiae.

scientific article

Tetrameric Ctp1 coordinates DNA binding and DNA bridging in DNA double-strand-break repair.

scientific article

The 3'-->5' exonuclease of DNA polymerase delta can substitute for the 5' flap endonuclease Rad27/Fen1 in processing Okazaki fragments and preventing genome instability

scientific article

The Cytidine Deaminase APOBEC3 Family Is Subject to Transcriptional Regulation by p53.

scientific article published on 23 February 2017

The Human TLR Innate Immune Gene Family Is Differentially Influenced by DNA Stress and p53 Status in Cancer Cells ⬇️

scientific article published on June 6, 2012

The Shu complex promotes error-free tolerance of alkylation-induced base excision repair products

scientific article published on 13 June 2016

The Toll-like receptor gene family is integrated into human DNA damage and p53 networks.

scientific article

The detection of chemically induced aneuploidy in Saccharomyces cerevisiae: an assessment of mitotic and meiotic systems

scientific article published on 01 January 1986

The detection of mitotic and meiotic chromosome gain in the yeast Saccharomyces cerevisiae: effects of methyl benzimidazol-2-yl carbamate, methyl methanesulfonate, ethyl methanesulfonate, dimethyl sulfoxide, propionitrile and cyclophosphamide monohy

scientific article

The flexible loop of human FEN1 endonuclease is required for flap cleavage during DNA replication and repair.

scientific article

The global role for Cdc13 and Yku70 in preventing telomere resection across the genome.

scientific article published on 29 November 2017

The novel p53 target TNFAIP8 variant 2 is increased in cancer and offsets p53-dependent tumor suppression

scientific article published on 11 November 2016

The organization and repair of DNA in the mammalian chromosome. II. A gradient-shape-induced speed dependence affecting DNAs larger than T4 DNA

scientific article published on 01 May 1977

The repair of double-strand breaks in DNA; a model involving recombination

scientific article published on June 1, 1976

The repair of double-strand breaks in the nuclear DNA of Saccharomyces cerevisiae and its genetic control

scientific article published on January 16, 1976

The role of recombination and RAD52 in mutation of chromosomal DNA transformed into yeast

scientific article published in October 1994

The sister chromatid cohesion pathway suppresses multiple chromosome gain and chromosome amplification.

scientific article published on 02 December 2013

Transactivation by low and high levels of human p53 reveals new physical rules of engagement and novel super-transactivation sequences

scientific article published on 24 October 2012

Transactivation specificity is conserved among p53 family proteins and depends on a response element sequence code

scientific article

Transformation-associated recombination (TAR) cloning of tumor-inducing Xmrk2 gene from Xiphophorus maculatus.

scientific article

Transformation-associated recombination between diverged and homologous DNA repeats is induced by strand breaks

scientific article published on 01 January 1994

Transposon Tn5 excision in yeast: influence of DNA polymerases alpha, delta, and epsilon and repair genes ⬇️

scientific article published on May 1, 1992

Unhealthy behaviors and psychosocial difficulties among overweight adolescents: the potential impact of familial factors

scientific article published in August 2002

Unrepaired double-strand breaks in nuclear DNA are not always lethal ⬇️

scientific article published on January 1, 1977

Use of a restriction endonuclease cytotoxicity assay to identify inducible GAL1 promoter variants with reduced basal activity.

scientific article published on 11 November 2005

Weight control behaviors among obese, overweight, and nonoverweight adolescents

scientific article published in September 2002

Weight-related sports involvement in girls: who is at risk for disordered eating?

scientific article published in July 2002

Yeast ARMs (DNA at-risk motifs) can reveal sources of genome instability ⬇️

scientific article published on May 25, 1998

Yeast RNC1 encodes a chimeric protein, RhoNUC, with a human rho motif and deoxyribonuclease activity ⬇️

scientific article published on October 11, 1992

Yeast as an honorary mammal

scientific article published on 01 June 2000

p53 amplifies Toll-like receptor 5 response in human primary and cancer cells through interaction with multiple signal transduction pathways

scientific article

p53 and NF-κB coregulate proinflammatory gene responses in human macrophages

scientific article published on April 2014

p53 mutants can often transactivate promoters containing a p21 but not Bax or PIG3 responsive elements

scientific article published in June 2001

p53 transactivation and the impact of mutations, cofactors and small molecules using a simplified yeast-based screening system

scientific article

p53-responsive TLR8 SNP enhances human innate immune response to respiratory syncytial virus

scientific article published on 01 November 2019

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