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List of works by Rune Toftgård

Antipsychotic drugs regulate hedgehog signaling by modulation of 7-dehydrocholesterol reductase levels

scientific article published on 17 June 2010

DYRK1B-dependent autocrine-to-paracrine shift of Hedgehog signaling by mutant RAS.

scientific article published on 30 May 2010

Development of mammary tumors by conditional expression of GLI1

scientific article published on 19 May 2009

Differential requirement of SUFU in tissue development discovered in a hypomorphic mouse model

scientific article

Epidermal and craniofacial defects in mice overexpressing Klf5 in the basal layer of the epidermis

scientific article

Genetic Elimination of Suppressor of Fused Reveals an Essential Repressor Function in the Mammalian Hedgehog Signaling Pathway

Genetic elimination of Suppressor of fused reveals an essential repressor function in the mammalian Hedgehog signaling pathway

scientific journal article

Hedgehog signaling and pancreatic tumor development

scientific article published on January 2011

Inhibition of GLI-mediated transcription and tumor cell growth by small-molecule antagonists

scholarly article

Inhibition of GLI1 gene activation by Patched1

scientific article

Loss of Trp53 promotes medulloblastoma development but not skin tumorigenesis in Sufu heterozygous mutant mice ⬇️

scientific article published on August 31, 2011

Non-canonical activation of GLI transcription factors: implications for targeted anti-cancer therapy

scientific article published on 30 July 2007

Novel human glioma-associated oncogene 1 (GLI1) splice variants reveal distinct mechanisms in the terminal transduction of the hedgehog signal

scientific article published on 31 March 2008

Targeted Expression of GLI1 in the Salivary Glands Results in an Altered Differentiation Program and Hyperplasia ⬇️

scientific article published on September 18, 2011

The Hedgehog pathway as a drug target in cancer therapy.

scientific article published on June 2007

Tumor necrosis factor receptor 1-mediated signaling is required for skin cancer development induced by NF-kappaB inhibition

scholarly article

Tumor suppressor gene co-operativity in compound Patched1 and suppressor of fused heterozygous mutant mice

scientific article published on May 2009

Wounding enhances epidermal tumorigenesis by recruiting hair follicle keratinocytes.

scientific article

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