List of works - Kevin M Jude

A human anti-IL-2 antibody that potentiates regulatory T cells by a structure-based mechanism

scientific article published on 25 June 2018

A strategy for the selection of monovalent antibodies that span protein dimer interfaces

scientific article published on 06 August 2019

Antibodies to Interleukin-2 Elicit Selective T Cell Subset Potentiation through Distinct Conformational Mechanisms.

scientific article published on May 2015

Atypical structural snapshots of human cytomegalovirus GPCR interactions with host G proteins

scientific article published on 21 January 2022

Deploying synthetic coevolution and machine learning to engineer protein-protein interactions

scientific article published on 27 July 2023

Design of protein-binding proteins from the target structure alone

scientific article published on 24 March 2022

Instructive roles for cytokine-receptor binding parameters in determining signaling and functional potency

scientific article

Interleukin-2 druggability is modulated by global conformational transitions controlled by a helical capping switch

scientific article published on 17 March 2020

Oxyanion-mediated inhibition of serine proteases

scientific article

Real-time detection of DNA topological changes with a fluorescently labeled cruciform.

scientific article published on 16 May 2013

Receptor subtype discrimination using extensive shape complementary designed interfaces

scientific article published on 13 May 2019

Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes.

scientific article

Stress-testing the relationship between T cell receptor/peptide-MHC affinity and cross-reactivity using peptide velcro.

scientific article

Structural Analysis of Charge Discrimination in the Binding of Inhibitors to Human Carbonic Anhydrases I and II

scientific article

Structural biology. Structural basis for Notch1 engagement of Delta-like 4

scientific article

Structural biology. Structural basis for chemokine recognition and activation of a viral G protein-coupled receptor

scientific article

Structure of a 129 Xe-Cryptophane Biosensor Complexed with Human Carbonic Anhydrase II

scientific article

Structure of human Frizzled5 by fiducial-assisted cryo-EM supports a heterodimeric mechanism of canonical Wnt signaling

scientific article published on 07 August 2020

Topological control of cytokine receptor signaling induces differential effects in hematopoiesis

scientific article

Viral GPCR US28 can signal in response to chemokine agonists of nearly unlimited structural degeneracy.

scientific article published on 8 June 2018

List of works by Kevin M Jude

A human anti-IL-2 antibody that potentiates regulatory T cells by a structure-based mechanism

A strategy for the selection of monovalent antibodies that span protein dimer interfaces

Antibodies to Interleukin-2 Elicit Selective T Cell Subset Potentiation through Distinct Conformational Mechanisms.

Atypical structural snapshots of human cytomegalovirus GPCR interactions with host G proteins

Deploying synthetic coevolution and machine learning to engineer protein-protein interactions

Design of protein-binding proteins from the target structure alone

Instructive roles for cytokine-receptor binding parameters in determining signaling and functional potency

Interleukin-2 druggability is modulated by global conformational transitions controlled by a helical capping switch

Oxyanion-mediated inhibition of serine proteases

Real-time detection of DNA topological changes with a fluorescently labeled cruciform.

Receptor subtype discrimination using extensive shape complementary designed interfaces

Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes.

Stress-testing the relationship between T cell receptor/peptide-MHC affinity and cross-reactivity using peptide velcro.

Structural Analysis of Charge Discrimination in the Binding of Inhibitors to Human Carbonic Anhydrases I and II

Structural biology. Structural basis for Notch1 engagement of Delta-like 4

Structural biology. Structural basis for chemokine recognition and activation of a viral G protein-coupled receptor

Structure of a 129 Xe-Cryptophane Biosensor Complexed with Human Carbonic Anhydrase II

Structure of human Frizzled5 by fiducial-assisted cryo-EM supports a heterodimeric mechanism of canonical Wnt signaling

Topological control of cytokine receptor signaling induces differential effects in hematopoiesis

Viral GPCR US28 can signal in response to chemokine agonists of nearly unlimited structural degeneracy.