List of works by Karine Clément

1,2-vinyldithiin from garlic inhibits differentiation and inflammation of human preadipocytes

scientific article published on 16 September 2009

11beta-hydroxysteroid dehydrogenase type 1 of the subcutaneous adipose tissue is dysregulated but not associated with metabolic disorders in adults born small for gestational age.

scientific article

A Data Integration Multi-Omics Approach to Study Calorie Restriction-Induced Changes in Insulin Sensitivity

scientific article published on 01 January 2018

A Dietary Supplement Containing Cinnamon, Chromium and Carnosine Decreases Fasting Plasma Glucose and Increases Lean Mass in Overweight or Obese Pre-Diabetic Subjects: A Randomized, Placebo-Controlled Trial

scientific article published on 25 September 2015

A PDGFRα-Mediated Switch toward CD9high Adipocyte Progenitors Controls Obesity-Induced Adipose Tissue Fibrosis.

scientific article published on 9 February 2017

A distinct adipose tissue gene expression response to caloric restriction predicts 6-mo weight maintenance in obese subjects

scientific article published on 26 October 2011

A frameshift mutation in human MC4R is associated with a dominant form of obesity

scientific article

A genetic variation in the 5' flanking region of the UCP3 gene is associated with body mass index in humans in interaction with physical activity

scientific article published on 01 February 2000

A genome-wide scan for human obesity genes reveals a major susceptibility locus on chromosome 10

scientific article published on 01 November 1998

A marker of endotoxemia is associated with obesity and related metabolic disorders in apparently healthy Chinese

scientific article

A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction

scientific article

A polymorphism in the 5' untranslated region of the human ob gene is associated with low leptin levels

scientific article published on 01 March 1998

A sib-pair analysis study of 15 candidate genes in French families with morbid obesity: indication for linkage with islet 1 locus on chromosome 5q.

scientific article published in February 1999

A surrogate of Roux-en-Y gastric bypass (the enterogastro anastomosis surgery) regulates multiple beta-cell pathways during resolution of diabetes in ob/ob mice

scientific article published on 30 July 2020

Accumulation and Changes in Composition of Collagens in Subcutaneous Adipose Tissue After Bariatric Surgery

scientific article published on 19 November 2015

Activin a plays a critical role in proliferation and differentiation of human adipose progenitors

scientific article

Acyl-CoA-Binding Protein Is a Lipogenic Factor that Triggers Food Intake and Obesity

scientific article published on 01 December 2019

Acyl-CoA-Binding Protein Is a Lipogenic Factor that Triggers Food Intake and Obesity

scientific article published on 15 August 2019

Adaptive expression of microRNA-125a in adipose tissue in response to obesity in mice and men.

scientific article

Additive effect of A-->G (-3826) variant of the uncoupling protein gene and the Trp64Arg mutation of the beta 3-adrenergic receptor gene on weight gain in morbid obesity

scientific article published on 01 December 1996

AdipoScan: A Novel Transient Elastography-Based Tool Used to Non-Invasively Assess Subcutaneous Adipose Tissue Shear Wave Speed in Obesity

scientific article published on 25 July 2016

Adipocyte ATP-binding cassette G1 promotes triglyceride storage, fat mass growth, and human obesity

scientific article published on 23 September 2014

Adipocyte size threshold matters: link with risk of type 2 diabetes and improved insulin resistance after gastric bypass

scientific article published on 29 April 2014

Adiponectin gene expression and plasma values in obese women during very-low-calorie diet. Relationship with cardiovascular risk factors and insulin resistance

scientific article published in February 2004

Adiponectin gene expression in subcutaneous adipose tissue of obese women in response to short-term very low calorie diet and refeeding

scientific article published in December 2003

Adiponutrin gene is regulated by insulin and glucose in human adipose tissue.

scientific article published in September 2006

Adiponutrin: A new gene regulated by energy balance in human adipose tissue

scientific article

Adipose angiotensinogen secretion, blood pressure, and AGT M235T polymorphism in obese patients

scientific article published in March 2004

Adipose gene expression prior to weight loss can differentiate and weakly predict dietary responders.

scientific article

Adipose tissue adaptive response to trans-10,cis-12-conjugated linoleic acid engages alternatively activated M2 macrophages.

scientific article published on 11 September 2015

Adipose tissue autophagy status in obesity: Expression and flux--two faces of the picture

scientific article published on 13 November 2015

Adipose tissue gene expression in obese subjects during low-fat and high-fat hypocaloric diets

scientific article published on 29 December 2004

Adipose tissue inflammation and liver pathology in human obesity

scientific article published on December 2008

Adipose tissue pathways involved in weight loss of cancer cachexia

scientific article

Adipose tissue remodeling in children: the link between collagen deposition and age-related adipocyte growth.

scientific article published on 18 January 2012

Adipose tissue transcriptome reflects variations between subjects with continued weight loss and subjects regaining weight 6 mo after caloric restriction independent of energy intake

scientific article published on 25 August 2010

Adipose tissue transcriptomic signature highlights the pathological relevance of extracellular matrix in human obesity

scientific article published on 21 January 2008

Adiposity signals, genetic and body weight regulation in humans

scientific article published in June 2004

AhR activation defends gut barrier integrity against damage occurring in obesity

scientific article published on 28 April 2020

Akkermansia muciniphila abundance is lower in severe obesity, but its increased level after bariatric surgery is not associated with metabolic health improvement

scientific article published on 02 July 2019

Akkermansia muciniphila and improved metabolic health during a dietary intervention in obesity: relationship with gut microbiome richness and ecology

scientific article

An early inflammatory gene profile in visceral adipose tissue in children

scientific article published on 24 May 2011

Analysis of sequence variability in the CART gene in relation to obesity in a Caucasian population

scientific article

Arginine-induced insulin release in glucokinase-deficient subjects

scientific article published on 01 September 1994

Assessment of insulin sensitivity in glucokinase-deficient subjects.

scientific article

Association between CST3 rs2424577 Polymorphism and Corpulence Related Phenotypes during Lifetime in Populations of European Ancestry

scientific article published on 15 April 2011

Association between genetic obesity susceptibility and mother-reported eating behaviour in children up to 5 years

scientific article published on 31 January 2019

Association between omental adipose tissue macrophages and liver histopathology in morbid obesity: influence of glycemic status.

scientific article

Association of Adipose Tissue and Liver Fibrosis With Tissue Stiffness in Morbid Obesity: Links With Diabetes and BMI Loss After Gastric Bypass

article by Meriem Abdennour et al published March 2014 in The Journal of Clinical Endocrinology and Metabolism

Association of poorly controlled diabetes with low serum leptin in morbid obesity ⬇️

scientific article published on 01 July 1997

Association of the Pro12Ala and C1431T Variants ofPPARγ and Their Haplotypes with Susceptibility to Gestational Diabetes

Associations between genetic obesity susceptibility and early postnatal fat and lean mass: an individual participant meta-analysis

scientific article published in December 2014

Atrial natriuretic peptide regulates adipose tissue accumulation in adult atria

scientific article published on 17 January 2017

Author Correction: Imidazole propionate is increased in diabetes and associated with dietary patterns and altered microbial ecology

scientific article published on 21 December 2020

Autophagy inhibition blunts PDGFRA adipose progenitors' cell-autonomous fibrogenic response to high-fat diet

scientific article published on 28 January 2020

Bariatric Surgery Induces Disruption in Inflammatory Signaling Pathways Mediated by Immune Cells in Adipose Tissue: A RNA-Seq Study

scientific article published on 4 May 2015

Benefits of massive weight loss on symptoms, systemic inflammation and cartilage turnover in obese patients with knee osteoarthritis

scientific article published on 26 October 2010

C-reactive protein levels in relation to various features of non-alcoholic fatty liver disease among obese patients

CCL5 promotes macrophage recruitment and survival in human adipose tissue

scientific article published on 5 November 2009

CD14dimCD16+ and CD14+CD16+ monocytes in obesity and during weight loss: relationships with fat mass and subclinical atherosclerosis

scientific article published on 28 July 2011

COVID-19 and its severity in bariatric surgery operated patients

scientific article published on 01 September 2020

COVID-19: a lever for the recognition of obesity as a disease? The French experience

scientific article published on 04 June 2020

Candidate gene approach of familial morbid obesity: linkage analysis of the glucocorticoid receptor gene

article

Cardiac MR Strain: A Noninvasive Biomarker of Fibrofatty Remodeling of the Left Atrial Myocardium

scientific article published on 16 August 2017

Cart overexpression is the only identifiable cause of high bone mass in melanocortin 4 receptor deficiency

scientific article

Cathepsin S genotypes are associated with Apo-A1 and HDL-cholesterol in lean and obese French populations.

scientific article published on 28 June 2008

Cathepsin S inhibition lowers blood glucose levels in mice.

scientific article published on 3 June 2014

Cathepsin S, a novel biomarker of adiposity: relevance to atherogenesis

Cathepsin s promotes human preadipocyte differentiation: possible involvement of fibronectin degradation

scientific article published on 6 July 2006

Cathepsins and cystatin C in atherosclerosis and obesity

scientific article published on 24 April 2010

Cathepsins in Human Obesity: Changes in Energy Balance Predominantly Affect Cathepsin S in Adipose Tissue and in Circulation.

scientific article published in March 2010

Cathepsins in human obesity: changes in energy balance predominantly affect cathepsin s in adipose tissue and in circulation

scientific article published on 17 February 2010

Chemerin correlates with markers for fatty liver in morbidly obese patients and strongly decreases after weight loss induced by bariatric surgery

scientific article published on 7 April 2010

Chronic intermittent hypoxia is a major trigger for non-alcoholic fatty liver disease in morbid obese

scientific article

Circulating Blood Monocyte Subclasses and Lipid-Laden Adipose Tissue Macrophages in Human Obesity

scientific article published on 21 July 2016

Circulating phospholipid profiling identifies portal contribution to NASH signature in obesity

scientific article published on 8 November 2014

Clinical phenotypes, insulin secretion, and insulin sensitivity in kindreds with maternally inherited diabetes and deafness due to mitochondrial tRNALeu(UUR) gene mutation

scientific article

Close linkage of glucokinase locus on chromosome 7p to early-onset non-insulin-dependent diabetes mellitus

scientific article published on March 12, 1992

Clustering biological annotations and gene expression data to identify putatively co-regulated biological processes

scientific article

Comparative Evaluation of Microbiota Engraftment Following Fecal Microbiota Transfer in Mice Models: Age, Kinetic and Microbial Status Matter

scientific article published on 01 January 2018

Comparison of body composition, basal metabolic rate and metabolic outcomes of adults with Prader Willi syndrome or lesional hypothalamic disease, with primary obesity

scientific article published on 15 January 2013

Continuous and Discrete Deep Classifiers for Data Integration

Contribution of energy restriction and macronutrient composition to changes in adipose tissue gene expression during dietary weight-loss programs in obese women

scientific article

Correction: A Dietary Supplement Containing Cinnamon, Chromium and Carnosine Decreases Fasting Plasma Glucose and Increases Lean Mass in Overweight or Obese Pre-Diabetic Subjects: A Randomized, Placebo-Controlled Trial

scientific article published on 14 December 2015

Correction: Genetic Polymorphisms and Weight Loss in Obesity: A Randomised Trial of Hypo-Energetic High- versus Low-Fat Diets.

scientific article

Corrigendum: Dietary intervention impact on gut microbial gene richness

scientific article published in Nature

Cultural Influences on the Regulation of Energy Intake and Obesity: A Qualitative Study Comparing Food Customs and Attitudes to Eating in Adults from France and the United States

scientific article published on 28 December 2020

DAPK2 Downregulation Associates With Attenuated Adipocyte Autophagic Clearance in Human Obesity

scientific article published on 2 June 2015

Deciphering the cellular interplays underlying obesity-induced adipose tissue fibrosis

scientific article published on 01 October 2019

Deep Self-Organising Maps for efficient heterogeneous biomedical signatures extraction

Deep kernel dimensionality reduction for scalable data integration

Defective leptin/leptin receptor signaling improves regulatory T cell immune response and protects mice from atherosclerosis

scientific article

Deficiency and inhibition of cathepsin K reduce body weight gain and increase glucose metabolism in mice

scientific article published on 25 September 2008

Deficiency in prohormone convertase PC1 impairs prohormone processing in Prader-Willi syndrome

scientific article published on 12 December 2016

Deficiency of FcϵR1 Increases Body Weight Gain but Improves Glucose Tolerance in Diet-Induced Obese Mice.

scientific article

Defining macrophage phenotype and function in adipose tissue

scientific article published on 26 May 2011

Determinants of human adipose tissue gene expression: impact of diet, sex, metabolic status, and cis genetic regulation

scientific article

Dietary Assessment in the MetaCardis Study: Development and Relative Validity of an Online Food Frequency Questionnaire

scientific article

Dietary Modulation of Gut Microbiota Contributes to Alleviation of Both Genetic and Simple Obesity in Children

scientific article published on 10 July 2015

Dietary factors and low-grade inflammation in relation to overweight and obesity

scientific article published on December 2011

Dietary factors impact on the association between CTSS variants and obesity related traits

scientific article (publication date: 2012)

Dietary intervention impact on gut microbial gene richness

scientific article

Dietary patterns differently associate with inflammation and gut microbiota in overweight and obese subjects

scientific article

Differential adaptation of human gut microbiota to bariatric surgery-induced weight loss: links with metabolic and low-grade inflammation markers ⬇️

scientific article

Differential effects of macronutrient content in 2 energy-restricted diets on cardiovascular risk factors and adipose tissue cell size in moderately obese individuals: a randomized controlled trial

scientific article published on 14 December 2011

Effect of Genotype and Previous GH Treatment on Adiposity in Adults With Prader-Willi Syndrome

scientific article published on 23 September 2016

Effect of bariatric surgery-induced weight loss on SR-BI-, ABCG1-, and ABCA1-mediated cellular cholesterol efflux in obese women

scientific article published on 2 February 2011

Effects of Diet-Modulated Autologous Fecal Microbiota Transplantation on Weight Regain

scientific article published on 26 August 2020

Effects of bariatric surgery on cardiac ectopic fat: lesser decrease in epicardial fat compared to visceral fat loss and no change in myocardial triglyceride content

scientific article published on 29 August 2012

Effects of bed-time insulin versus pioglitazone on abdominal fat accumulation, inflammation and gene expression in adipose tissue in patients with type 2 diabetes

scientific article published on 15 August 2009

Elevated CETP activity improves plasma cholesterol efflux capacity from human macrophages in women

scientific article published on 16 August 2012

Elevated expression of osteopontin may be related to adipose tissue macrophage accumulation and liver steatosis in morbid obesity

scientific article published on 24 October 2008

Elevated plasma ghrelin levels in Prader–Willi syndrome

article by David E. Cummings et al published July 2002 in Nature Medicine

Elevated serum ceramides are linked with obesity-associated gut dysbiosis and impaired glucose metabolism

scientific article published on 11 October 2019

Emerging role of cathepsin S in obesity and its associated diseases

scientific article published on January 2007

Endogenous CETP activity as a predictor of cardiovascular risk: determination of the optimal range

scientific article

Endothelial cells from visceral adipose tissue disrupt adipocyte functions in a three-dimensional setting: partial rescue by angiopoietin-1

scientific article published on 15 October 2013

Epicardial fat volume is associated with coronary microvascular response in healthy subjects: a pilot study

scientific article

Evaluation of a melanocortin-4 receptor (MC4R) agonist (Setmelanotide) in MC4R deficiency

scientific article published on 8 July 2017

Expression of NLRP3 inflammasome and T cell population markers in adipose tissue are associated with insulin resistance and impaired glucose metabolism in humans.

scientific article published on 8 February 2012

Expression of adrenomedullin in human epicardial adipose tissue: role of coronary status

scientific article published on 18 September 2007

Fasting-induced FGF21 is repressed by LXR activation via recruitment of an HDAC3 corepressor complex in mice

scientific article

Fate and complex pathogenic effects of dioxins and polychlorinated biphenyls in obese subjects before and after drastic weight loss

scientific article

Fecal Microbiota Transplantation: a Future Therapeutic Option for Obesity/Diabetes?

scientific article published on 27 June 2019

Fibrosis and adipose tissue dysfunction

scientific article published on 15 August 2013

Fibrosis in human adipose tissue: composition, distribution, and link with lipid metabolism and fat mass loss

scientific article

From correlation to causality: the case of <i>Subdoligranulum</i>

scientific article published on 01 November 2020

FunNet: an integrative tool for exploring transcriptional interactions

scientific article published in 2008

GAD2 on chromosome 10p12 is a candidate gene for human obesity

scientific article

GLUT2 accumulation in enterocyte apical and intracellular membranes: a study in morbidly obese human subjects and ob/ob and high fat-fed mice

scientific article

GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMI

scientific article published on 04 September 2019

Gamma-synuclein is an adipocyte-neuron gene coordinately expressed with leptin and increased in human obesity

scientific article

Gender effect of the Trp64Arg mutation in the beta 3 adrenergic receptor gene on weight gain in morbid obesity

scientific article published in November 1997

Gene expression profiling of human skeletal muscle in response to stabilized weight loss

scientific article published in July 2008

Genetic architecture of early childhood growth phenotypes gives insights into their link with later obesity

Genetic association and gene expression analysis identify FGFR1 as a new susceptibility gene for human obesity

scientific journal article

Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice

scientific article published on 26 July 2009

Genetic determination of plasma cholesterol efflux capacity is gender-specific and independent of HDL-cholesterol levels

scientific article published on 31 January 2013

Genetic polymorphisms and weight loss in obesity: a randomised trial of hypo-energetic high- versus low-fat diets

scientific article

Genetic studies of neuropeptide Y and neuropeptide Y receptors Y1 and Y5 regions in morbid obesity ⬇️

scientific article published on June 1, 1997

Genetic studies of the leptin receptor gene in morbidly obese French Caucasian families

scientific article

Genetic studies of the sulfonylurea receptor gene locus in NIDDM and in morbid obesity among French Caucasians

scientific article published in April 1997

Genetic variation in the beta 3-adrenergic receptor and an increased capacity to gain weight in patients with morbid obesity

scientific article

Genetics and the pathophysiology of obesity

scientific article

Genetics of human obesity

article

Genetics of obesity

scientific article

Genetics of obesity: towards the understanding of a complex syndrome.

scientific article published in March 2000

Genome wide association study identifies KCNMA1 contributing to human obesity

scientific article

Genome-wide Linkage Analysis for Severe Obesity in French Caucasians Finds Significant Susceptibility Locus on Chromosome 19q

article

Genome-wide association study of non-alcoholic fatty liver and steatohepatitis in a histologically-characterised cohort

scientific article published on 13 April 2020

Genomic and epigenomic regulation of adipose tissue inflammation in obesity

scientific article published on 27 October 2013

Genotype-by-nutrient interactions assessed in European obese women

scientific article published on 01 November 2006

Gut Microbiota Dysbiosis in Human Obesity: Impact of Bariatric Surgery

scientific article published on 01 September 2019

Gut Microbiota Profile of Obese Diabetic Women Submitted to Roux-en-Y Gastric Bypass and Its Association with Food Intake and Postoperative Diabetes Remission

scientific article published on 21 January 2020

Gut microbiota after gastric bypass in human obesity: increased richness and associations of bacterial genera with adipose tissue genes

scientific article

Gut microbiota and human NAFLD: disentangling microbial signatures from metabolic disorders

scientific article published on 09 March 2020

Gut microbiota and non-alcoholic fatty liver disease: new insights

scientific article published on 02 March 2013

Gut microbiota and obesity: Concepts relevant to clinical care

scientific article published on 27 October 2017

Gut microbiota of obese subjects with Prader-Willi syndrome is linked to metabolic health

scientific article published on 14 October 2019

Harnessing the beneficial properties of adipogenic microbes for improving human health.

scientific article

Heat Shock Protein 60 in Obesity: Effect of Bariatric Surgery and its Relation to Inflammation and Cardiovascular Risk

scientific article

Hepatic stellate cell hypertrophy is associated with metabolic liver fibrosis

scientific article published on 02 March 2020

High levels of CRP in morbid obesity: the central role of adipose tissue and lessons for clinical practice before and after bariatric surgery

scientific article published on 18 June 2014

Histopathological algorithm and scoring system for evaluation of liver lesions in morbidly obese patients

scientific article published in November 2012

Homozygous leptin receptor mutation due to uniparental disomy of chromosome 1: response to bariatric surgery

scientific article published on 28 December 2012

Homozygous null mutation of the melanocortin-4 receptor and severe early-onset obesity

scientific article published in June 2007

Human Adipocytes Induce Inflammation and Atrophy in Muscle Cells During Obesity

scientific article published on 18 February 2015

Human adipocyte function is impacted by mechanical cues

scientific article published on 01 June 2014

Human adipose tissue macrophages: m1 and m2 cell surface markers in subcutaneous and omental depots and after weight loss

scientific article published on 16 October 2009

Human catalase gene promoter haplotype and cardiometabolic improvement after bariatric surgery

scientific article published on 27 February 2018

Human epicardial adipose tissue has a specific transcriptomic signature depending on its anatomical peri-atrial, peri-ventricular, or peri-coronary location

scientific article

Human epicardial adipose tissue induces fibrosis of the atrial myocardium through the secretion of adipo-fibrokines.

scientific article published on 22 March 2013

Hypoadiponectinaemia and high risk of type 2 diabetes are associated with adiponectin-encoding (ACDC) gene promoter variants in morbid obesity: evidence for a role of ACDC in diabesity

article

Imidazole propionate is increased in diabetes and associated with dietary patterns and altered microbial ecology

scientific article published on 18 November 2020

Immune cell-derived cytokines contribute to obesity-related inflammation, fibrogenesis and metabolic deregulation in human adipose tissue.

scientific article

Impact of bacterial probiotics on obesity, diabetes and non-alcoholic fatty liver disease related variables: a systematic review and meta-analysis of randomised controlled trials

scientific article published on 30 March 2019

Impact of bariatric surgery on type 2 diabetes: contribution of inflammation and gut microbiome?

scientific article published on 25 April 2019

Implication of the Pro12Ala polymorphism of the PPAR-gamma 2 gene in type 2 diabetes and obesity in the French population

scientific article

In obese and non-obese adults, the cis-regulatory rs361072 promoter variant of PIK3CB is associated with insulin resistance not with type 2 diabetes

scholarly article by Karine Clément et al published March 2009 in Molecular Genetics and Metabolism

In vivo epinephrine-mediated regulation of gene expression in human skeletal muscle

scientific article

In vivo regulation of human skeletal muscle gene expression by thyroid hormone

scientific article

Increased Basement Membrane Components in Adipose Tissue During Obesity: Links With TGFβ and Metabolic Phenotypes.

scientific article

Increased adipose tissue oxygen tension in obese compared with lean men is accompanied by insulin resistance, impaired adipose tissue capillarization, and inflammation

scientific article published on 13 June 2011

Increased infiltration of macrophages in omental adipose tissue is associated with marked hepatic lesions in morbid human obesity.

scientific article published in June 2006

Increased jejunal permeability in human obesity is revealed by a lipid challenge and is linked to inflammation and type 2 diabetes

scientific article published on 28 August 2018

Indication for linkage of the human OB gene region with extreme obesity

scientific article

Influence of polymorphisms in candidate genes on early vascular alterations in obese children.

scientific article published on 29 November 2009

Insulin resistance and inflammation predict kinetic body weight changes in response to dietary weight loss and maintenance in overweight and obese subjects by using a Bayesian network approach

scientific article published on 30 October 2013

Insulin secretion and insulin sensitivity in diabetic and non-diabetic subjects with hepatic nuclear factor-1alpha (maturity-onset diabetes of the young-3) mutations

scientific article published on 01 December 1999

Insulin secretory abnormalities in subjects with hyperglycemia due to glucokinase mutations

scientific article

Interactional and functional centrality in transcriptional co-expression networks

scientific article published on 19 October 2010

Interpretable and accurate prediction models for metagenomics data

scientific article published on 01 March 2020

Interpretable and accurate prediction models for metagenomics data

Intima-media thickness in severe obesity: links with BMI and metabolic status but not with systemic or adipose tissue inflammation

scientific article published on 23 September 2013

Irf5 deficiency in macrophages promotes beneficial adipose tissue expansion and insulin sensitivity during obesity.

scientific article

Is obesity an inflammatory illness? Role of low-grade inflammation and macrophage infiltration in human white adipose tissue

scientific article published on 10 August 2006

Jejunal T Cell Inflammation in Human Obesity Correlates with Decreased Enterocyte Insulin Signaling.

scientific article

Knee and hip intra-articular adipose tissues (IAATs) compared with autologous subcutaneous adipose tissue: a specific phenotype for a central player in osteoarthritis

scientific article published on 15 March 2017

Krüppel-like factor 4 regulates macrophage polarization

scientific article

Lactobacillus rhamnosus CNCMI-4317 Modulates Fiaf/Angptl4 in Intestinal Epithelial Cells and Circulating Level in Mice.

scientific article published on 6 October 2015

Left atrium dysfunction by CMR in aortic valve stenosis.

scientific article published on 3 February 2015

Leptin and genetics of obesity

scientific article published on 01 January 1997

Leptin and leptin receptor-related monogenic obesity

scientific article published on 22 May 2012

Leptin receptor gene in a large cohort of massively obese subjects: no indication of the fa/fa rat mutation. Detection of an intronic variant with no association with obesity

scientific article

Leptin regulation of bone resorption by the sympathetic nervous system and CART

scientific journal article

Leptin therapy for partial lipodystrophy linked to a PPAR-gamma mutation

scientific article published on 10 December 2007

Linkage and association studies between the proopiomelanocortin (POMC) gene and obesity in caucasian families

scientific article

Lipid-rich diet enhances L-cell density in obese subjects and in mice through improved L-cell differentiation

scientific article published on 20 May 2015

Liquid chromatography-mass spectrometry-based parallel metabolic profiling of human and mouse model serum reveals putative biomarkers associated with the progression of nonalcoholic fatty liver disease

scientific article

Liver X receptor (LXR) regulates human adipocyte lipolysis

scientific article

Long-term Relapse of Type 2 Diabetes After Roux-en-Y Gastric Bypass: Prediction and Clinical Relevance

scientific article published on 06 August 2018

Losing weight for a better health: Role for the gut microbiota

scientific article published on 01 April 2016

Lysosomal Acid Lipase Drives Adipocyte Cholesterol Homeostasis and Modulates Lipid Storage in Obesity, Independent of Autophagy

scientific article published on 02 November 2020

L’altération de la perméabilité intestinale : chaînon manquant entre dysbiose et inflammation au cours de l’obésité ?

scientific article published on 25 May 2016

MC4R agonism promotes durable weight loss in patients with leptin receptor deficiency

MECHANISMS IN ENDOCRINOLOGY: Update on treatments for patients with genetic obesity

scientific article published on 01 November 2020

Macrophage activation marker soluble CD163 and non-alcoholic fatty liver disease in morbidly obese patients undergoing bariatric surgery.

scientific article published on August 2015

Macrophage-secreted factors impair human adipogenesis: involvement of proinflammatory state in preadipocytes

scientific article published on 2 November 2006

Macrophage-secreted factors promote a profibrotic phenotype in human preadipocytes

scientific article

Major microbiota dysbiosis in severe obesity: fate after bariatric surgery

scientific article published on 13 June 2018

Mast cells in human adipose tissue: link with morbid obesity, inflammatory status, and diabetes.

scientific article

Mediation and modification of genetic susceptibility to obesity by eating behaviors

scientific article published on 16 August 2017

Medication cost is significantly reduced after Roux-en-Y gastric bypass in obese patients

scientific article

Melanocortin 4 receptor mutations in a large cohort of severely obese adults: prevalence, functional classification, genotype-phenotype relationship, and lack of association with binge eating

scientific article

Melanocortin-4 receptor mutations and polymorphisms do not affect weight loss after bariatric surgery

scientific article

Melanocortin-4 receptor mutations are a frequent and heterogeneous cause of morbid obesity

scientific article

Metabolic and adipose tissue signatures in adults with Prader-Willi syndrome: a model of extreme adiposity

scientific article published on 5 December 2014

Metabolism and Metabolic Disorders and the Microbiome: The intestinal microbiota associated with obesity, lipid metabolism and metabolic health: pathophysiology and therapeutic strategies

scientific article published on 27 November 2020

Metabolite profiling identifies candidate markers reflecting the clinical adaptations associated with Roux-en-Y gastric bypass surgery

scientific article

Microarray analysis of genes with impaired insulin regulation in the skeletal muscle of type 2 diabetic patients indicates the involvement of basic helix-loop-helix domain-containing, class B, 2 protein (BHLHB2).

scientific article published on 10 July 2009

Microarray profiling of human skeletal muscle reveals that insulin regulates approximately 800 genes during a hyperinsulinemic clamp

scientific article published on 5 March 2003

Microarray profiling of human white adipose tissue after exogenous leptin injection.

scientific article published on March 2006

Microbiome and metabolome features of the cardiometabolic disease spectrum

scientific article published on 17 February 2022

Micronutrient and Protein Deficiencies After Gastric Bypass and Sleeve Gastrectomy: a 1-year Follow-up

scientific article published on 01 April 2016

Molecular genetics of human obesity-associated MC4R mutations

scientific article

Mucosal-associated invariant T (MAIT) cells are depleted and prone to apoptosis in cardiometabolic disorders

scientific article published on 27 April 2018

Mucosal-associated invariant T cell alterations in obese and type 2 diabetic patients

scientific article

Mutation analysis of the MCHR1 gene in human obesity

scientific article

Mutation screening and association studies of the human uncoupling protein 3 gene in normoglycemic and diabetic morbidly obese patients

scientific article published on 01 January 1999

Mutation screening of the human UCP 2 gene in normoglycemic and NIDDM morbidly obese patients: lack of association between new UCP 2 polymorphisms and obesity in French Caucasians.

scientific article

Mutation screening of the urocortin gene: identification of new single nucleotide polymorphisms and association studies with obesity in French Caucasians

scientific article published on 01 February 2002

Mutational analysis of melanocortin-4 receptor, agouti-related protein, and α-melanocyte-stimulating hormone genes in severely obese children

article

Mutational analysis of the pro-opiomelanocortin gene in French obese children led to the identification of a novel deleterious heterozygous mutation located in the alpha-melanocyte stimulating hormone domain

scientific article

Needle and surgical biopsy techniques differentially affect adipose tissue gene expression profiles.

scientific article published on 3 December 2008

Neutral lipid storage disease with myopathy: a whole-body nuclear MRI and metabolic study

scientific article published on 28 December 2012

Nonalcoholic Fatty Liver Disease: Modulating Gut Microbiota to Improve Severity?

scientific article published on 08 February 2020

Noninvasive diagnosis of nonalcoholic steatohepatitis disease based on clinical decision support system.

scientific article published in January 2013

Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits

scientific article published on 12 October 2020

Novel pharmacological MC4R agonists can efficiently activate mutated MC4R from obese patient with impaired endogenous agonist response

scientific article published on 9 August 2010

Nutritional and Protein Deficiencies in the Short Term following Both Gastric Bypass and Gastric Banding

scientific article published on 18 February 2016

OBEDIS Core Variables Project: European Expert Guidelines on a Minimal Core Set of Variables to Include in Randomized, Controlled Clinical Trials of Obesity Interventions

scientific article published on 16 January 2020

Obesity and low-grade inflammation: a paediatric perspective

scientific article published on 21 October 2009

Obesity-associated mutations in the melanocortin 4 receptor provide novel insights into its function

scientific article

Obesity-dependent metabolic signatures associated with nonalcoholic fatty liver disease progression

scientific article published on 15 March 2012

Performance of biomarkers FibroTest, ActiTest, SteatoTest, and NashTest in patients with severe obesity: meta analysis of individual patient data

scientific article

Pharmacokinetics of immunomodulator treatments after roux-en-y bypass in obese patient

scientific article published on 14 May 2013

Pharmacology of morphine in obese patients: clinical implications

scientific article published on January 2009

Phosphatidylglycerols are induced by gut dysbiosis and inflammation, and favorably modulate adipose tissue remodeling in obesity

scientific article published on 04 January 2019

Pilot study examining the frequency of several gene polymorphisms involved in morphine pharmacodynamics and pharmacokinetics in a morbidly obese population

scientific article published in August 2011

Plasma NOV/CCN3 levels are closely associated with obesity in patients with metabolic disorders

scientific article

Polymorphisms in the amino acid transporter solute carrier family 6 (neurotransmitter transporter) member 14 gene contribute to polygenic obesity in French Caucasians

scientific article

Positional candidate gene analysis of Lim domain homeobox gene (Isl-1) on chromosome 5q11-q13 in a French morbidly obese population suggests indication for association with type 2 diabetes

scientific article published in May 2002

Potential contribution of adipose tissue to elevated serum cystatin C in human obesity

scientific article published on 9 April 2009

Prediction of Long-Term Diabetes Remission After RYGB, Sleeve Gastrectomy, and Adjustable Gastric Banding Using DiaRem and Advanced-DiaRem Scores

scientific article published on 01 March 2019

Primary pancreatic beta-cell secretory defect caused by mutations in glucokinase gene in kindreds of maturity onset diabetes of the young.

scientific article published in August 1992

Profiling of the three circulating monocyte subpopulations in human obesity

scientific article published on 18 March 2015

Promoter adiponectin polymorphisms and waist/hip ratio variation in a prospective French adults study

scientific article published on 11 December 2007

Proopiomelanocortin Deficiency Treated with a Melanocortin-4 Receptor Agonist

scientific article

Prospective assessment and histological analysis of adherent perinephric fat in partial nephrectomies

scientific article published on 27 October 2016

Quantifying Diet-Induced Metabolic Changes of the Human Gut Microbiome.

scientific article

Rare Genetic Forms of Obesity: Clinical Approach and Current Treatments in 2016.

scientific article published on June 2016

Rare melanocortin-3 receptor mutations with in vitro functional consequences are associated with human obesity ⬇️

scientific article published on 03 November 2010

Reduction of macrophage infiltration and chemoattractant gene expression changes in white adipose tissue of morbidly obese subjects after surgery-induced weight loss

scientific article

Regulation of inflammation-related genes in human adipose tissue.

scientific article published on October 2007

Relationship between adiposity, emotional status and eating behaviour in obese women: role of inflammation

scientific article published on 20 October 2010

Relationship between single nucleotide polymorphisms in leptin, IL6 and adiponectin genes and their circulating product in morbidly obese subjects before and after gastric banding surgery

scientific article published on 01 January 2005

Relative Adipose Tissue Failure in Alström Syndrome Drives Obesity-Induced Insulin Resistance

scientific article published on 29 September 2020

Relevance of increased serum cystatin C to vascular alterations in obese children

scientific article published on 01 June 2012

Relevance of omental pericellular adipose tissue collagen in the pathophysiology of human abdominal obesity and related cardiometabolic risk

scientific article published on 4 October 2016

Reply to C Matuchansky

scientific article published on 01 March 2014

Reply: To PMID 22939560.

scientific article published in March 2013

Resistance Training and Protein Supplementation Increase Strength After Bariatric Surgery: A Randomized Controlled Trial

scientific article published on 01 November 2018

Response to Comment on Pellegrinelli et al. Human Adipocytes Induce Inflammation and Atrophy in Muscle Cells During Obesity. Diabetes 2015;64:3121–3134

Retinol-binding protein 4 and prediction of incident coronary events in healthy men and women

scientific article

Revealing links between gut microbiome and its fungal community in Type 2 Diabetes Mellitus among Emirati subjects: A pilot study

scientific article published on 15 June 2020

Richness of human gut microbiome correlates with metabolic markers

scientific article (publication date: 29 August 2013)

Role of serum amyloid a in adipocyte-macrophage cross talk and adipocyte cholesterol efflux

scientific article published on 17 February 2009

Role of the DGAT Gene C79T Single‐Nucleotide Polymorphism in French Obese Subjects ⬇️

scientific article published on October 1, 2003

Role of transcription factor KLF11 and its diabetes-associated gene variants in pancreatic beta cell function

scientific article

Roles of chemokine ligand-2 (CXCL2) and neutrophils in influencing endothelial cell function and inflammation of human adipose tissue

scientific article published on 31 January 2013

SMRT-GPS2 corepressor pathway dysregulation coincides with obesity-linked adipocyte inflammation

scientific article

SREBF-1 gene polymorphisms are associated with obesity and type 2 diabetes in French obese and diabetic cohorts

scientific article published on 01 August 2004

Saturated Fat Is More Metabolically Harmful for the Human Liver Than Unsaturated Fat or Simple Sugars

scientific article published on 29 May 2018

Secretory type II phospholipase A2 is produced and secreted by epicardial adipose tissue and overexpressed in patients with coronary artery disease

scientific article published on 11 December 2009

Semaphorin 3C is a novel adipokine linked to extracellular matrix composition.

scientific article published on 12 May 2013

Senescence-associated β-galactosidase in subcutaneous adipose tissue associates with altered glycaemic status and truncal fat in severe obesity

scientific article published on 30 October 2020

Serum amyloid A and obstructive sleep apnea syndrome before and after surgically-induced weight loss in morbidly obese subjects

scientific article published in November 2006

Serum amyloid A: a marker of adiposity-induced low-grade inflammation but not of metabolic status

scientific article published on 01 February 2006

Serum amyloid A: production by human white adipocyte and regulation by obesity and nutrition

article

Serum lipidomics reveals early differential effects of gastric bypass compared with banding on phospholipids and sphingolipids independent of differences in weight loss.

scientific article

Short-term overfeeding may induce peripheral insulin resistance without altering subcutaneous adipose tissue macrophages in humans ⬇️

scientific article

Single nucleotide polymorphisms of protein tyrosine phosphatase 1B gene are associated with obesity in morbidly obese French subjects

scientific article published on 3 July 2004

Single-nucleotide polymorphism haplotypes in the both proximal promoter and exon 3 of the APM1 gene modulate adipocyte-secreted adiponectin hormone levels and contribute to the genetic risk for type 2 diabetes in French Caucasians

scientific article published in October 2002

Slimming down via the microbiota

scientific article published in November 2013

Social Imagination and Solidarity in Precarious Times: The Case of Lower Class People in Post-Soviet Russia

scholarly article by Karine Clément published 2017 in Sociologičeskoe Obozrenie

Soluble leptin receptor in serum of subjects with complete resistance to leptin: relation to fat mass.

scientific article

Solute carrier family 2 member 1 is involved in the development of nonalcoholic fatty liver disease

scientific article

Sparse Zero-Sum Games as Stable Functional Feature Selection

scientific article published on September 2015

Statin therapy is associated with lower prevalence of gut microbiota dysbiosis

scientific article published on 06 May 2020

Statins, antidiabetic medications and liver histology in patients with diabetes with non-alcoholic fatty liver disease

scientific article published on 18 March 2016

Structural and inflammatory heterogeneity in subcutaneous adipose tissue: relation with liver histopathology in morbid obesity

scientific article

Synergistic convergence of microbiota-specific systemic IgG and secretory IgA

scientific article published on 13 December 2018

Systematic review of bariatric surgery liver biopsies clarifies the natural history of liver disease in patients with severe obesity

scientific article published on 24 November 2016

T Cell Populations and Functions Are Altered in Human Obesity and Type 2 Diabetes.

scientific article published in September 2017

T cell-derived IL-22 amplifies IL-1β-driven inflammation in human adipose tissue: relevance to obesity and type 2 diabetes.

scientific article published on 11 February 2014

TM6SF2 rs58542926 influences hepatic fibrosis progression in patients with non-alcoholic fatty liver disease

scientific article

The Eating Inventory and body adiposity from leanness to massive obesity: a study of 2509 adults

scientific article published in December 2004

The FAT Score, a Fibrosis Score of Adipose Tissue: Predicting Weight-Loss Outcome After Gastric Bypass

scientific article published on 17 April 2017

The Pro115Gln and Pro12Ala PPAR gamma gene mutations in obesity and type 2 diabetes

scientific article published on 01 March 2000

The Transcriptional Coactivator Peroxisome Proliferator Activated Receptor (PPAR) Coactivator-1 and the Nuclear Receptor PPAR Control the Expression of Glycerol Kinase and Metabolism Genes Independently of PPAR Activation in Human White Adipocytes

article

The advanced-DiaRem score improves prediction of diabetes remission 1 year post-Roux-en-Y gastric bypass

scientific article

The case for strategic international alliances to harness nutritional genomics for public and personal health

scientific article

The effects of gastrointestinal surgery on gut microbiota: potential contribution to improved insulin sensitivity

scientific article

The gut microbiome, diet, and links to cardiometabolic and chronic disorders

scientific article published on 30 November 2015

The human gut microbiota contributes to type-2 diabetes non-resolution 5-years after Roux-en-Y gastric bypass

scientific article published on 01 January 2022

The importance of the gut microbiota after bariatric surgery

scientific article published on 28 August 2012

The intestinal microbiota regulates host cholesterol homeostasis

scientific article published on 27 November 2019

The mid-infrared spectroscopy: A novel non-invasive diagnostic tool for NASH diagnosis in severe obesity

scientific article published on 23 October 2019

Transcriptomic profiling across the nonalcoholic fatty liver disease spectrum reveals gene signatures for steatohepatitis and fibrosis

scientific article published on 01 December 2020

Transcriptomic signatures of villous cytotrophoblast and syncytiotrophoblast in term human placenta.

scientific article published on 6 June 2016

Transcriptomics applied to obesity and caloric restriction.

scientific article

Treatment for 2 mo with n 3 polyunsaturated fatty acids reduces adiposity and some atherogenic factors but does not improve insulin sensitivity in women with type 2 diabetes: a randomized controlled study

scientific article published on 01 December 2007

Type 2 Diabetes Remission After Gastric Bypass: What Is the Best Prediction Tool for Clinicians?

scientific article published on 01 July 2015

Type 2 diabetes is associated with impaired jejunal enteroendocrine GLP-1 cell lineage in human obesity

scientific article published on 09 October 2020

Unexpected endocrine features and normal pigmentation in a young adult patient carrying a novel homozygous mutation in the POMC gene

scientific article published on 02 September 2008

Unraveling the genetics of human obesity

scientific article

Urokinase Plasminogen Activator Receptor in Adipose Tissue Macrophages of Morbidly Obese Subjects

scientific article published on 16 February 2011

Use of HOMA-IR to diagnose non-alcoholic fatty liver disease: a population-based and inter-laboratory study

scientific article published on 29 June 2017

Using gene expression to predict the secretome of differentiating human preadipocytes.

scientific article published on 17 February 2009

Valsartan improves adipose tissue function in humans with impaired glucose metabolism: a randomized placebo-controlled double-blind trial

scientific article (publication date: 2012)

Variants of ENPP1 are associated with childhood and adult obesity and increase the risk of glucose intolerance and type 2 diabetes

scientific article published on 17 July 2005

Variation in the use of skull radiographs by emergency physicians in young children with minor head trauma

scientific article

Variations in circulating inflammatory factors are related to changes in calorie and carbohydrate intakes early in the course of surgery-induced weight reduction

scientific article published on 15 June 2011

Visceral Adipose Tissue Drives Cardiac Aging Through Modulation of Fibroblast Senescence by Osteopontin Production.

scientific article published on 2 March 2018

Weight Loss After Sleeve Gastrectomy: Does Type 2 Diabetes Status Impact Weight and Body Composition Trajectories?

scientific article published on 04 November 2020

Weight Loss, Xanthine Oxidase, and Serum Urate Levels: A Prospective Longitudinal Study of Obese Patients

scientific article published on 25 November 2015

Weight loss reduces adipose tissue cathepsin S and its circulating levels in morbidly obese women

scientific article published on 4 January 2006

Weight loss regulates inflammation-related genes in white adipose tissue of obese subjects

scientific article published in November 2004

Weight of pericardial fat on coronaropathy

scientific article published in May 2009

[Adipose tissue fibrosis: an aggravating factor in obesity]

scientific article published on 01 May 2018

[Adipose tissue, a new playground for immune cells]

scientific article published on 30 November 2011

[Genetic aspects of obesity]

scientific article published on 21 May 2007

[Is obesity an inflammatory disease?]

scientific article published on 01 January 2006

[Lipo-atrophic diabetes, "a rare disease of adipocytes?"]

scientific article published on 01 May 1994

[Monitoring adherence after weight loss surgery: Identifying factors leading to non-adherence in a cohort of 207 severely obese patients who have undergone surgery. An evaluation of severely obese patients’ adherence following weight loss surgery.]

scientific article published on 01 September 2018

[What about a new job in the health system: The coordinator of care]

scientific article published on 26 July 2014

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