List of works - Paul Young

A novel dry powder inhalable formulation incorporating three first-line anti-tubercular antibiotics

scientific article

A novel inhalable form of rifapentine

scientific article published on March 2014

A rifapentine-containing inhaled triple antibiotic formulation for rapid treatment of tubercular infection

scientific article published on 16 November 2013

Agglomerate properties and dispersibility changes of salmeterol xinafoate from powders for inhalation after storage at high relative humidity.

scientific article published on 8 April 2009

Artesunate-clindamycin multi-kinetics and site-specific oral delivery system for antimalaric combination products

scientific article published on 10 May 2010

Co-spray-dried mannitol-ciprofloxacin dry powder inhaler formulation for cystic fibrosis and chronic obstructive pulmonary disease

scientific article

Combination of Silver Nanoparticles and Curcumin Nanoparticles for Enhanced Anti-biofilm Activities

scientific article published on 23 November 2015

Controlled release antibiotics for dry powder lung delivery

scientific article published in January 2010

Correlation between compactibility values and excipient cluster size using anin silicoapproach ⬇️

scientific article published on May 9, 2012

Cospray dried antibiotics for dry powder lung delivery

scientific article published in August 2008

Delivery of high solubility polyols by vibrating mesh nebulizer to enhance mucociliary clearance

scientific article

Development of an in vivo ovine dry powder inhalation model for the evaluation of conventional and controlled release microparticles

scientific article published on July 2009

Does electrostatic charge affect powder aerosolisation?

scientific article published in May 2010

Effect of Humidity on Aerosolization of Micronized Drugs ⬇️

scientific article published on October 1, 2003

Immunomodulatory effects of a low-dose clarithromycin-based macrolide solution pressurised metered dose inhaler

scientific article published on 24 December 2014

Implications and emerging control strategies for ventilator-associated infections.

scientific article

Influence of humidity on the electrostatic charge and aerosol performance of dry powder inhaler carrier based systems

scientific article published on 22 March 2007

Influence of storage relative humidity on the dispersion of salmeterol xinafoate powders for inhalation

scientific article published in March 2009

Introduction of the electrical next generation impactor (eNGI) and investigation of its capabilities for the study of pressurized metered dose inhalers

scientific article published on 31 October 2008

Lactose composite carriers for respiratory delivery

scientific article

Mannitol delivery by vibrating mesh nebulisation for enhancing mucociliary clearance

scientific article

Measuring charge and mass distributions in dry powder inhalers using the electrical Next Generation Impactor (eNGI).

scientific article published on 24 June 2009

Micro-particle corrugation, adhesion and inhalation aerosol efficiency

scientific article

Multi-breath dry powder inhaler for delivery of cohesive powders in the treatment of bronchiectasis

scientific article published on 9 May 2014

Murine pharmacokinetics of rifapentine delivered as an inhalable dry powder

scientific article published on 16 December 2014

Non-cytotoxic silver nanoparticle-polyvinyl alcohol hydrogels with anti-biofilm activity: designed as coatings for endotracheal tube materials

scientific article published on 01 January 2014

Novel nano-cellulose excipient for generating non-Newtonian droplets for targeted nasal drug delivery.

scientific article published on 5 June 2017

Overcoming dose limitations using the orbital(®) multi-breath dry powder inhaler

scientific article

Particle aerosolisation and break-up in dry powder inhalers 1: evaluation and modelling of venturi effects for agglomerated systems

scientific article

Particle aerosolisation and break-up in dry powder inhalers: evaluation and modelling of impaction effects for agglomerated systems

scientific article

Particle aerosolisation and break-up in dry powder inhalers: evaluation and modelling of the influence of grid structures for agglomerated systems

scientific article

Pharmacopeial methodologies for determining aerodynamic mass distributions of ultra-high dose inhaler medicines

scientific article published on 29 October 2009

Preparation and characterisation of controlled release co-spray dried drug-polymer microparticles for inhalation 1: influence of polymer concentration on physical and in vitro characteristics

scientific article published on 31 December 2007

Preparation and characterisation of controlled release co-spray dried drug-polymer microparticles for inhalation 2: evaluation of in vitro release profiling methodologies for controlled release respiratory aerosols

scientific article published on 22 April 2008

Preparation and evaluation of controlled release microparticles for respiratory protein therapy

scientific article

Recent advances in controlled release pulmonary therapy

scientific article published on August 2009

Role of agglomeration in the dispersion of salmeterol xinafoate from mixtures for inhalation with differing drug to fine lactose ratios

scientific article published in August 2008

Scanning white-light interferometry as a novel technique to quantify the surface roughness of micron-sized particles for inhalation

scientific article

Silver nanoparticles enhance Pseudomonas aeruginosa PAO1 biofilm detachment

scientific article published on 17 April 2013

Solid lipid budesonide microparticles for controlled release inhalation therapy

scientific article

Superhydrophobic, nanotextured polyvinyl chloride films for delaying Pseudomonas aeruginosa attachment to intubation tubes and medical plastics

scientific article published on 18 January 2012

Surface energy changes and their relationship with the dispersibility of salmeterol xinafoate powders for inhalation after storage at high RH.

scientific article published on 2 September 2009

The Effect of Active Pharmaceutical Ingredients on Aerosol Electrostatic Charges from Pressurized Metered Dose Inhalers

scientific article published on 19 March 2015

The contribution of different formulation components on the aerosol charge in carrier-based dry powder inhaler systems

scientific article published on 31 March 2010

The development of a single-use, capsule-free multi-breath tobramycin dry powder inhaler for the treatment of cystic fibrosis

scientific article published on 5 April 2016

The effect of actuator nozzle designs on the electrostatic charge generated in pressurised metered dose inhaler aerosols

scientific article published in October 2014

The effect of ethanol on the formation and physico-chemical properties of particles generated from budesonide solution-based pressurized metered-dose inhalers

scientific article

The effects of mannitol on the transport of ciprofloxacin across respiratory epithelia

scientific article published on 11 July 2013

The formulation, chemical and physical characterisation of clarithromycin-based macrolide solution pressurised metered dose inhaler

scientific article

The influence of actuator materials and nozzle designs on electrostatic charge of pressurised metered dose inhaler (pMDI) formulations

scientific article published on 3 December 2013

The influence of drug morphology on aerosolisation efficiency of dry powder inhaler formulations

scientific article published in July 2008

The influence of flow rate on the aerosol deposition profile and electrostatic charge of single and combination metered dose inhalers

scientific article published on 6 October 2009

The influence of mechanical processing of dry powder inhaler carriers on drug aerosolization performance

scientific article published in May 2007

The use of computational approaches in inhaler development

scientific article published on 23 October 2011

List of works by Paul Young

A novel dry powder inhalable formulation incorporating three first-line anti-tubercular antibiotics

A novel inhalable form of rifapentine

A rifapentine-containing inhaled triple antibiotic formulation for rapid treatment of tubercular infection

Agglomerate properties and dispersibility changes of salmeterol xinafoate from powders for inhalation after storage at high relative humidity.

Artesunate-clindamycin multi-kinetics and site-specific oral delivery system for antimalaric combination products

Co-spray-dried mannitol-ciprofloxacin dry powder inhaler formulation for cystic fibrosis and chronic obstructive pulmonary disease

Combination of Silver Nanoparticles and Curcumin Nanoparticles for Enhanced Anti-biofilm Activities

Controlled release antibiotics for dry powder lung delivery

Correlation between compactibility values and excipient cluster size using anin silicoapproach ⬇️

Cospray dried antibiotics for dry powder lung delivery

Delivery of high solubility polyols by vibrating mesh nebulizer to enhance mucociliary clearance

Development of an in vivo ovine dry powder inhalation model for the evaluation of conventional and controlled release microparticles

Does electrostatic charge affect powder aerosolisation?

Effect of Humidity on Aerosolization of Micronized Drugs ⬇️

Immunomodulatory effects of a low-dose clarithromycin-based macrolide solution pressurised metered dose inhaler

Implications and emerging control strategies for ventilator-associated infections.

Influence of humidity on the electrostatic charge and aerosol performance of dry powder inhaler carrier based systems

Influence of storage relative humidity on the dispersion of salmeterol xinafoate powders for inhalation

Introduction of the electrical next generation impactor (eNGI) and investigation of its capabilities for the study of pressurized metered dose inhalers

Lactose composite carriers for respiratory delivery

Mannitol delivery by vibrating mesh nebulisation for enhancing mucociliary clearance

Measuring charge and mass distributions in dry powder inhalers using the electrical Next Generation Impactor (eNGI).

Micro-particle corrugation, adhesion and inhalation aerosol efficiency

Multi-breath dry powder inhaler for delivery of cohesive powders in the treatment of bronchiectasis

Murine pharmacokinetics of rifapentine delivered as an inhalable dry powder

Non-cytotoxic silver nanoparticle-polyvinyl alcohol hydrogels with anti-biofilm activity: designed as coatings for endotracheal tube materials

Novel nano-cellulose excipient for generating non-Newtonian droplets for targeted nasal drug delivery.

Overcoming dose limitations using the orbital(®) multi-breath dry powder inhaler

Particle aerosolisation and break-up in dry powder inhalers 1: evaluation and modelling of venturi effects for agglomerated systems

Particle aerosolisation and break-up in dry powder inhalers: evaluation and modelling of impaction effects for agglomerated systems

Particle aerosolisation and break-up in dry powder inhalers: evaluation and modelling of the influence of grid structures for agglomerated systems

Pharmacopeial methodologies for determining aerodynamic mass distributions of ultra-high dose inhaler medicines

Preparation and characterisation of controlled release co-spray dried drug-polymer microparticles for inhalation 1: influence of polymer concentration on physical and in vitro characteristics

Preparation and characterisation of controlled release co-spray dried drug-polymer microparticles for inhalation 2: evaluation of in vitro release profiling methodologies for controlled release respiratory aerosols

Preparation and evaluation of controlled release microparticles for respiratory protein therapy

Recent advances in controlled release pulmonary therapy

Role of agglomeration in the dispersion of salmeterol xinafoate from mixtures for inhalation with differing drug to fine lactose ratios

Scanning white-light interferometry as a novel technique to quantify the surface roughness of micron-sized particles for inhalation

Silver nanoparticles enhance Pseudomonas aeruginosa PAO1 biofilm detachment

Solid lipid budesonide microparticles for controlled release inhalation therapy

Superhydrophobic, nanotextured polyvinyl chloride films for delaying Pseudomonas aeruginosa attachment to intubation tubes and medical plastics

Surface energy changes and their relationship with the dispersibility of salmeterol xinafoate powders for inhalation after storage at high RH.

The Effect of Active Pharmaceutical Ingredients on Aerosol Electrostatic Charges from Pressurized Metered Dose Inhalers

The contribution of different formulation components on the aerosol charge in carrier-based dry powder inhaler systems

The development of a single-use, capsule-free multi-breath tobramycin dry powder inhaler for the treatment of cystic fibrosis

The effect of actuator nozzle designs on the electrostatic charge generated in pressurised metered dose inhaler aerosols

The effect of ethanol on the formation and physico-chemical properties of particles generated from budesonide solution-based pressurized metered-dose inhalers

The effects of mannitol on the transport of ciprofloxacin across respiratory epithelia

The formulation, chemical and physical characterisation of clarithromycin-based macrolide solution pressurised metered dose inhaler

The influence of actuator materials and nozzle designs on electrostatic charge of pressurised metered dose inhaler (pMDI) formulations

The influence of drug morphology on aerosolisation efficiency of dry powder inhaler formulations

The influence of flow rate on the aerosol deposition profile and electrostatic charge of single and combination metered dose inhalers

The influence of mechanical processing of dry powder inhaler carriers on drug aerosolization performance

The use of computational approaches in inhaler development

Understanding lactose behaviour during storage by monitoring surface energy change using inverse gas chromatography