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List of works by Ebba Nexø

4-ethylphenyl-cobalamin impairs tissue uptake of vitamin B12 and causes vitamin B12 deficiency in mice

scientific article (publication date: 2013)

89Zr-Cobalamin PET Tracer: Synthesis, Cellular Uptake, and Use for Tumor Imaging

scientific article

A new principle for measurement of cobalamin and corrinoids, used for studies of cobalamin analogs on serum haptocorrin.

scientific article published on 19 March 2009

A soluble form of the macrophage-related mannose receptor (MR/CD206) is present in human serum and elevated in critical illness

scientific article published on 01 March 2014

Absorption and retention of free and milk protein-bound cyano- and hydroxocobalamins. An experimental study in rats

scientific article published on 25 November 2015

Analytical validation of the Roche 25-OH Vitamin D Total assay

scientific article published on 01 November 2012

Biochemical signs of impaired cobalamin status during and after radiotherapy for rectal cancer

scientific article published in November 2004

Biomarkers of vitamin B-12 status in NHANES: a roundtable summary

scientific article

Breast milk vitamin B-12 concentrations in Guatemalan women are correlated with maternal but not infant vitamin B-12 status at 12 months postpartum.

scientific article published on 30 November 2011

Calcium-induced apoptosis is delayed by HER1 receptor signalling through the Akt and PLCγ pathways in bladder cancer cells.

scientific article published on 18 November 2010

Changes in basal and postmethionine load concentrations of total homocysteine and cystathionine after B vitamin intervention

scientific article published on 01 September 2004

Circulating HER2 DNA after trastuzumab treatment predicts survival and response in breast cancer.

scientific article

Circulating serum trefoil factors increase dramatically during pregnancy

scientific article published on 01 January 2008

Circulating tyrosinase and MART-1 mRNA does not independently predict relapse or survival in patients with AJCC stage I-II melanoma

scientific article published on 01 April 2006

Co-expression of HER3 and MUC1 is associated with a favourable prognosis in patients with bladder cancer

scientific article published on 01 January 2015

Cobalamin analogues in humans: a study on maternal and cord blood.

scientific article

Cobalamin coenzyme forms are not likely to be superior to cyano- and hydroxyl-cobalamin in prevention or treatment of cobalamin deficiency.

scientific article published on 12 May 2015

Comparative Bioavailability of Synthetic B12 and Dietary Vitamin B12 Present in Cow and Buffalo Milk: A Prospective Study in Lactovegetarian Indians

scientific article published on 01 February 2019

Comparison of recombinant human haptocorrin expressed in human embryonic kidney cells and native haptocorrin

scientific article

Complete pathologic response in lung tumors in two patients with metastatic non-small cell lung cancer treated with erlotinib

scientific article published on 01 November 2011

Cyano-B12 or Whey Powder with Endogenous Hydroxo-B12 for Supplementation in B12 Deficient Lactovegetarians

scientific article published on 06 October 2019

Detection of EGFR mutations in plasma and biopsies from non-small cell lung cancer patients by allele-specific PCR assays.

scientific article

Detection of Vitamin B12 Deficiency in Older People by Measuring Vitamin B12 or the Active Fraction of Vitamin B12, Holotranscobalamin

scientific article published on 15 March 2007

Dietary Intake of Vitamin B12 is Better for Restoring a Low B12 Status Than a Daily High-Dose Vitamin Pill: An Experimental Study in Rats

scientific article published on 15 August 2018

Differences in Tissue Distribution of Cyano⁻B12 and Hydroxo⁻B12 One Week after Oral Intake: An Experimental Study in Male Wistar Rats

scientific article published on 12 October 2018

Does a conjugation site affect transport of vitamin B12-PNA conjugates into bacterial cells?

scientific article published on 15 November 2018

Down-regulation of S100C is associated with bladder cancer progression and poor survival.

scientific article published on January 2005

EGFR mutation frequency and effectiveness of erlotinib: a prospective observational study in Danish patients with non-small cell lung cancer.

scientific article

Early changes in vitamin B12 uptake and biomarker status following Roux-en-Y gastric bypass and sleeve gastrectomy

scientific article published on 15 February 2018

Effect of 8-week oral supplementation with 3-µg cyano-B12 or hydroxo-B12 in a vitamin B12-deficient population.

scientific article published on 5 December 2017

Effect of the vitamin B12-binding protein haptocorrin present in human milk on a panel of commensal and pathogenic bacteria.

scientific article

Effects of Prolonged Whey Protein Supplementation and Resistance Training on Biomarkers of Vitamin B12 Status: A 1-Year Randomized Intervention in Healthy Older Adults (the CALM Study)

scientific article published on 07 July 2020

Elevated plasma vitamin B12 levels as a marker for cancer: a population-based cohort study

scientific article

Elevated vitamin B12 levels in autoimmune lymphoproliferative syndrome attributable to elevated haptocorrin in lymphocytes

scientific article published on January 28, 2012

Enzymatic extraction of cobalamin from monoclonal antibody captured haptocorrin and transcobalamin

scientific article published on 25 September 2007

Expression of PIK3CA, PTEN mRNA and PIK3CA mutations in primary breast cancer: association with lymph node metastases

scientific article published on 16 September 2013

Expression of the epidermal growth factor system in endometrioid endometrial cancer

scientific article published on 07 September 2006

Expression of the epidermal growth factor system in eutopic endometrium from women with endometriosis differs from that in endometrium from healthy women.

scientific article

Expression of the epidermal growth factor system in human middle ear cholesteatoma

scientific article published on 21 November 2013

Expression of transforming growth factor alpha and epidermal growth factor receptor in human bladder cancer

scientific article published on 01 July 1999

Facts and recommendations about total homocysteine determinations: an expert opinion

scientific article

False low holotranscobalamin levels in a patient with a novel TCN2 mutation

scientific article published on 01 November 2016

First trimester serum levels of the soluble transcobalamin receptor, holo-transcobalamin, and total transcobalamin in relation to preeclampsia risk.

scientific article published on 4 October 2016

Folate and vitamin B12 in relation to lactation: a 9-month postpartum follow-up study.

scientific article published in January 2006

Folate and vitamin B12 status in relation to cognitive impairment and anaemia in the setting of voluntary fortification in the UK.

scientific article published on 17 March 2008

Gastrointestinal Handling of Water-Soluble Vitamins

scientific article published on 14 September 2018

Haptocorrin in humans

scientific article

Holo-transcobalamin is an early marker of changes in cobalamin homeostasis. A randomized placebo-controlled study.

scientific article published in October 2002

Holo-transcobalamin is an indicator of vitamin B-12 absorption in healthy adults with adequate vitamin B-12 status.

scientific article published in April 2007

Holotranscobalamin remains unchanged during pregnancy. Longitudinal changes of cobalamins and their binding proteins during pregnancy and postpartum

scientific article published on 01 December 2007

Holotranscobalamin, a marker of vitamin B-12 status: analytical aspects and clinical utility

scientific article

Hypoxia changes the expression of the epidermal growth factor (EGF) system in human hearts and cultured cardiomyocytes.

scientific article

Identification of multidrug resistance protein 1 (MRP1/ABCC1) as a molecular gate for cellular export of cobalamin.

scientific article published on 6 November 2009

Increase in circulating holotranscobalamin after oral administration of cyanocobalamin or hydroxocobalamin in healthy adults with low and normal cobalamin status.

scientific article

Inhibition of the epidermal growth factor receptor in bladder cancer cells treated with the DNA-damaging drug etoposide markedly increases apoptosis.

scientific article published on January 2007

Insulin induces a transcriptional activation of epiregulin, HB-EGF and amphiregulin, by a PI3K-dependent mechanism: identification of a specific insulin-responsive promoter element

scientific article published on 18 January 2007

Kinetic analysis of transcellular passage of the cobalamin-transcobalamin complex in Caco-2 monolayers

scientific article published on 19 December 2018

Long term biweekly 1 mg oral vitamin B12 ensures normal hematological parameters, but does not correct all other markers of vitamin B12 deficiency. A study in patients with inherited vitamin B12 deficiency

scientific article published on 02 September 2008

Long-term Outcome of 4 Patients With Transcobalamin Deficiency Caused by 2 Novel TCN2 Mutations.

scientific article published on 22 May 2017

Low vitamin B-12 status and risk of cognitive decline in older adults.

scientific article published in November 2007

Maximal load of the vitamin B12 transport system: a study on mice treated for four weeks with high-dose vitamin B12 or cobinamide

scientific article

Measurement of amino terminal propeptide of type III procollagen (PIIINP) employing the ADVIA Centaur platform. Validation, reference interval and comparison to UniQ RIA

scientific article published on 01 February 2014

Metformin increases liver accumulation of vitamin B12 - an experimental study in rats.

scientific article published on 10 February 2013

Metformin induces reductions in plasma cobalamin and haptocorrin bound cobalamin levels in elderly diabetic patients.

scientific article published on 6 March 2010

Molecular Dissection of the Intrinsic Factor-Vitamin B12Receptor, Cubilin, Discloses Regions Important for Membrane Association and Ligand Binding

scientific article published in Journal of Biological Chemistry

Monitoring of epidermal growth factor receptor tyrosine kinase inhibitor-sensitizing and resistance mutations in the plasma DNA of patients with advanced non-small cell lung cancer during treatment with erlotinib

scientific article

More on Failures of Cobalamin Assays in Pernicious Anemia

scientific article published on October 18, 2012

Mouse transcobalamin has features resembling both human transcobalamin and haptocorrin

scientific article

Nutritional 1C Imbalance, B12 Tissue Accumulation, and Pregnancy Outcomes: An Experimental Study in Rats

scientific article published on 26 October 2018

Organometallic B12-DNA conjugate: synthesis, structure analysis, and studies of binding to human B12-transporter proteins.

scientific article published on 28 August 2014

Organometallic DNA-B12 Conjugates as Potential Oligonucleotide Vectors: Synthesis and Structural and Binding Studies with Human Cobalamin-Transport Proteins.

scientific article

PET imaging of patients with non-small cell lung cancer employing an EGF receptor targeting drug as tracer.

scientific article published on 17 November 2011

Plasma vitamin B6 vitamers before and after oral vitamin B6 treatment: a randomized placebo-controlled study

scientific article published in January 2003

Positron emission tomography (PET) imaging with [11C]-labeled erlotinib: a micro-PET study on mice with lung tumor xenografts.

scientific article

Promoter hypomethylation and upregulation of trefoil factors in prostate cancer.

scientific article published in October 2010

Quantification of melanoma cell-specific MART-1 mRNA in peripheral blood by a calibrated competitive reverse transcription-PCR

scientific article published on 01 December 2000

Quantitation of the mRNA expression of the epidermal growth factor system: selective induction of heparin-binding epidermal growth factor-like growth factor and amphiregulin expression by growth factor stimulation of prostate stromal cells

scientific article published on 01 September 2000

Quantitative PCR--new diagnostic tool for quantifying specific mRNA and DNA molecules: HER2/neu DNA quantification with LightCycler real-time PCR in comparison with immunohistochemistry and fluorescence in situ hybridization.

scientific article published in January 2004

Quantitative analysis of the human epidermal growth factor receptor messenger RNA using reverse transcription-PCR: a methodological study of imprecision

scientific article published on June 1, 1998

Real-time polymerase chain reaction is a sensitive and precise method for quantifying transcription from reporter plasmids.

scientific article published on January 2004

S100beta protein in peripheral blood may predict progressive disease during interleukin-2 based immunotherapy in patients with metastatic melanoma.

scientific article published in June 2004

Salivary acetylcholinesterase activity is increased in Parkinson's disease: a potential marker of parasympathetic dysfunction.

scientific article published on 12 February 2015

Screening for vitamin B-12 and folate deficiency in older persons

scientific article published on 01 May 2003

Sensitive automated ELISA for measurement of vitamin D-binding protein (Gc) in human urine

scientific article published on 01 June 2005

Seven Patients With Transcobalamin Deficiency Diagnosed Between 2010 and 2014: A Single-Center Experience.

scientific article

Simultaneous quantitation of several mRNA species by calibrated reverse transcription polymerase chain reaction and capillary electrophoresis: analysis of the epidermal growth factor receptor and its activating ligands EGF, TGF-alpha, and HB-EGF in

scientific article published on 01 June 2000

Soluble transcobalamin receptor, sCD320, is present in human serum and relates to serum cobalamin - establishment and validation of an ELISA.

scientific article published on 5 December 2011

Stability of 35 biochemical and immunological routine tests after 10 hours storage and transport of human whole blood at 21°C

scientific article

Systemic administration of insulin-like growth factor I (IGF-I) causes growth of the rat prostate

scientific article published on 01 July 1997

Systemic treatment with epidermal growth factor but not insulin-like growth factor I decreases the involution of the prostate in castrated rats

scientific article published on 01 April 2000

Systemically Administered Plant Recombinant Holo-Intrinsic Factor Targets the Liver and is not Affected by Endogenous B12 levels

scientific article published on 22 August 2019

Testosterone Measured with an Automatic Immunoassay Compares Reasonably Well to Results Obtained by LC-MS/MS.

scientific article published in October 2016

The HER4 isoform JM-a/CYT2 relates to improved survival in bladder cancer patients but only if the estrogen receptor α is not expressed.

scientific article published on September 2013

The cobalamin-binding protein in zebrafish is an intermediate between the three cobalamin-binding proteins in human

scientific article

The relation between survival and expression of HER1 and HER2 depends on the expression of HER3 and HER4: a study in bladder cancer patients

scientific article published on June 2006

The soluble receptor for vitamin B12 uptake (sCD320) increases during pregnancy and occurs in higher concentration in urine than in serum

scientific article

The soluble transcobalamin receptor (sCD320) in relation to Alzheimer's disease and cognitive scores.

scientific article published on 9 May 2017

The soluble transcobalamin receptor (sCD320) is present in cerebrospinal fluid and correlates to dementia-related biomarkers tau proteins and amyloid-beta.

scientific article published on 24 July 2015

The tissue profile of metabolically active coenzyme forms of vitamin B12 differs in vitamin B12-depleted rats treated with hydroxo-B12 or cyano-B12

scientific article published on 01 July 2018

The transcobalamin (TC) codon 259 genetic polymorphism influences holo-TC concentration in cerebrospinal fluid from patients with Alzheimer disease

scientific journal article

The transcobalamin 776C > G polymorphism may be a modifiable genetic risk factor for Alzheimer's disease

scientific article published on 01 June 2005

The vitamin B12 absorption test, CobaSorb, identifies patients not requiring vitamin B12 injection therapy

scientific article published on 30 May 2011

Three family members with elevated plasma cobalamin, transcobalamin and soluble transcobalamin receptor (sCD320).

scientific article

Tissue distribution of oral vitamin B12 is influenced by B12 status and B12 form: an experimental study in rats.

scientific article published on 20 March 2017

Towards quantitative mRNA analysis in paraffin-embedded tissues using real-time reverse transcriptase-polymerase chain reaction: a methodological study on lymph nodes from melanoma patients

scientific article

Transcobalamin II deficiency at birth.

scientific article

Transcobalamin Polymorphism 67A->G, but Not 776C->G, Affects Serum Holotranscobalamin in a Cohort of Healthy Middle-Aged Men and Women

Transcobalamin deficiency caused by compound heterozygosity for two novel mutations in the TCN2 gene: a study of two affected siblings, their brother, and their parents

scientific article published on 06 July 2010

Transcobalamin from cow milk: isolation and physico-chemical properties

scientific article published on 01 January 1996

Treatment response in vitamin B12 deficiency depends on the chosen vitamin B12 preparation

scientific article published on October 17, 2011

Trefoil factor family peptides are increased in the saliva of children with mucositis

scientific article published on 28 July 2011

Trefoil factor family peptides in human saliva and cyclical cervical mucus. Method evaluation and results on healthy individuals.

scientific article

Trefoil factor family peptides in the human foetus and at birth

scientific article published on 25 February 2011

Trefoil factor peptide 3 is positively correlated with the viscoelastic properties of the cervical mucus plug

scientific article published on 12 October 2016

Trefoil factor peptides in serum and sputum from subjects with asthma and COPD

scientific article published on 16 June 2014

Trefoil factors (TFFs) are increased in bronchioalveolar lavage fluid from patients with chronic obstructive lung disease (COPD)

scientific article published on 23 October 2014

Trefoil factors in human milk

scientific article published on 23 May 2008

Tumor imaging in patients with advanced tumors using a new (99m) Tc-radiolabeled vitamin B12 derivative

scientific article published on 12 December 2013

Unexpected high plasma cobalamin : proposal for a diagnostic strategy.

scientific article

Uptake of cobalamin and markers of cobalamin status: a longitudinal study of healthy pregnant women.

scientific article

Validation of commercial assays for measurements of trefoil factor family peptides in serum.

scientific article

Vitamin B-12 treatment has limited effect on health-related quality of life among individuals with elevated plasma methylmalonic acid: a randomized placebo-controlled study.

scientific article published in February 2003

Vitamin B12 Therapy in Older Adults and Misconception of Its Inappropriateness

scientific article published on 01 November 2019

Vitamin B12 absorption judged by measurement of holotranscobalamin, active vitamin B12: evaluation of a commercially available EIA kit

scientific article published on 14 October 2011

Vitamin B12 and its binding proteins in milk from cow and buffalo in relation to bioavailability of B12

scientific article published on 28 March 2019

Vitamin B12 and its binding proteins in patients with non-small cell lung cancer referred to fast-track diagnostic work-up for lung cancer

scientific article published on 18 November 2019

Vitamin B₁₂ and its binding proteins in hepatocellular carcinoma and chronic liver diseases

scientific article published on 24 June 2014

Vitamin B₁₂ dependent changes in mouse spinal cord expression of vitamin B₁₂ related proteins and the epidermal growth factor system.

scientific article

Vitamin B12 Phosphate Conjugation and Its Effect on Binding to the Human B12 -Binding Proteins Intrinsic Factor and Haptocorrin

scientific article published on 27 April 2016