List of works - Bing Xiong

BSSF: a fingerprint based ultrafast binding site similarity search and function analysis server

scientific article

CCLab—a multi-objective genetic algorithm based combinatorial library design software and an application for histone deacetylase inhibitor design ⬇️

scientific article published on June 7, 2012

Crystal Structures of Two Aminoglycoside Kinases Bound with a Eukaryotic Protein Kinase Inhibitor

scientific article

Crystallization and preliminary crystallographic analysis of an aminoglycoside kinase from Legionella pneumophila

scientific article

Design and Synthesis of (R)‐1‐Arylsulfonylpiperidine‐2‐carboxamides as 11β‐Hydroxysteroid Dehydrogenase Type 1 Inhibitors ⬇️

scientific article published on March 7, 2013

Design and Synthesis of 4‐(2,4,5‐Trifluorophenyl)butane‐1,3‐diamines as Dipeptidyl Peptidase IV Inhibitors ⬇️

scientific article published on May 13, 2013

Design and Synthesis of Potent, Selective Inhibitors of Protein Arginine Methyltransferase 4 against Acute Myeloid Leukemia

scientific article published on 04 June 2019

Design, synthesis and SAR of piperidyl-oxadiazoles as 11β-hydroxysteroid dehydrogenase 1 inhibitors ⬇️

scientific article published on January 10, 2013

Discovery of 3H‐Imidazo[4,5‐b]pyridines as Potent c‐Met Kinase Inhibitors: Design, Synthesis, and Biological Evaluation ⬇️

scientific article published on May 13, 2012

Discovery of benzhydrylpiperazine derivatives as CB1 receptor inverse agonists via privileged structure-based approach

scientific article

Discovery of novel sulfonamides as potent and selective inhibitors against human and mouse 11β-hydroxysteroid dehydrogenase type 1 ⬇️

scientific article published on March 3, 2012

Energetic factors determining the binding of type I inhibitors to c-Met kinase: experimental studies and quantum mechanical calculations

scientific article

Fragment-Based Drug Discovery of 2-Thiazolidinones as Inhibitors of the Histone Reader BRD4 Bromodomain ⬇️

scientific article published on May 14, 2013

MT119, a new planar‐structured compound, targets the colchicine site of tubulin arresting mitosis and inhibiting tumor cell proliferation ⬇️

scientific article published on November 3, 2010

MT7, a novel compound from a combinatorial library, arrests mitosis via inhibiting the polymerization of microtubules

scientific article published on 25 August 2009

Potent and novel 11β-HSD1 inhibitors identified from shape and docking based virtual screening ⬇️

scientific article published on 08 August 2011

Structural analysis of a novel cyclohexylamine oxidase from Brevibacterium oxydans IH-35A

scientific article

Structure of the Antibiotic Resistance Factor Spectinomycin Phosphotransferase from Legionella pneumophila

scientific article

Structure-Based Discovery and Development of a Series of Potent and Selective Bromodomain and Extra-Terminal Protein Inhibitors

scientific article published on 16 September 2019

Structures of aminoglycoside acetyltransferase AAC(6')-Ii in a novel crystal form: structural and normal-mode analyses.

scientific article

Sulfated polymannuroguluronate inhibits Tat-induced SLK cell adhesion via a novel binding site, a KKR spatial triad ⬇️

scientific article published on April 18, 2011

The type IA topoisomerase catalytic cycle: A normal mode analysis and molecular dynamics simulation

scientific article published on June 2008

Virtual Screening and Structure-Based Discovery of Indole Acylguanidines as Potent β-secretase (BACE1) Inhibitors ⬇️

scientific article published on May 16, 2013

List of works by Bing Xiong

BSSF: a fingerprint based ultrafast binding site similarity search and function analysis server

CCLab—a multi-objective genetic algorithm based combinatorial library design software and an application for histone deacetylase inhibitor design ⬇️

Crystal Structures of Two Aminoglycoside Kinases Bound with a Eukaryotic Protein Kinase Inhibitor

Crystallization and preliminary crystallographic analysis of an aminoglycoside kinase from Legionella pneumophila

Design and Synthesis of (R)‐1‐Arylsulfonylpiperidine‐2‐carboxamides as 11β‐Hydroxysteroid Dehydrogenase Type 1 Inhibitors ⬇️

Design and Synthesis of 4‐(2,4,5‐Trifluorophenyl)butane‐1,3‐diamines as Dipeptidyl Peptidase IV Inhibitors ⬇️

Design and Synthesis of Potent, Selective Inhibitors of Protein Arginine Methyltransferase 4 against Acute Myeloid Leukemia

Design, synthesis and SAR of piperidyl-oxadiazoles as 11β-hydroxysteroid dehydrogenase 1 inhibitors ⬇️

Discovery of 3H‐Imidazo[4,5‐b]pyridines as Potent c‐Met Kinase Inhibitors: Design, Synthesis, and Biological Evaluation ⬇️

Discovery of benzhydrylpiperazine derivatives as CB1 receptor inverse agonists via privileged structure-based approach

Discovery of novel sulfonamides as potent and selective inhibitors against human and mouse 11β-hydroxysteroid dehydrogenase type 1 ⬇️

Energetic factors determining the binding of type I inhibitors to c-Met kinase: experimental studies and quantum mechanical calculations

Fragment-Based Drug Discovery of 2-Thiazolidinones as Inhibitors of the Histone Reader BRD4 Bromodomain ⬇️

MT119, a new planar‐structured compound, targets the colchicine site of tubulin arresting mitosis and inhibiting tumor cell proliferation ⬇️

MT7, a novel compound from a combinatorial library, arrests mitosis via inhibiting the polymerization of microtubules

Potent and novel 11β-HSD1 inhibitors identified from shape and docking based virtual screening ⬇️

Structural analysis of a novel cyclohexylamine oxidase from Brevibacterium oxydans IH-35A

Structure of the Antibiotic Resistance Factor Spectinomycin Phosphotransferase from Legionella pneumophila

Structure-Based Discovery and Development of a Series of Potent and Selective Bromodomain and Extra-Terminal Protein Inhibitors

Structures of aminoglycoside acetyltransferase AAC(6')-Ii in a novel crystal form: structural and normal-mode analyses.

Sulfated polymannuroguluronate inhibits Tat-induced SLK cell adhesion via a novel binding site, a KKR spatial triad ⬇️

The type IA topoisomerase catalytic cycle: A normal mode analysis and molecular dynamics simulation

Virtual Screening and Structure-Based Discovery of Indole Acylguanidines as Potent β-secretase (BACE1) Inhibitors ⬇️