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List of works by Bruce R Blazar

161533 TriKE stimulates NK-cell function to overcome myeloid-derived suppressor cells in MDS

scientific article published on 01 June 2018

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one

scientific article (publication date: November 2016)

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two: National Harbor, MD, USA. 9-13 November 2016

scientific article published oln 16 November 2016

4-1BB and CD28 signaling plays a synergistic role in redirecting umbilical cord blood T cells against B-cell malignancies

scientific article

<i>Salmonella</i>-Based Therapy Targeting Indoleamine 2,3-Dioxygenase Restructures the Immune Contexture to Improve Checkpoint Blockade Efficacy

scientific article published on 16 December 2020

A Bortezomib-Based Regimen Offers Promising Survival and Graft-versus-Host Disease Prophylaxis in Myeloablative HLA-Mismatched and Unrelated Donor Transplantation: A Phase II Trial

scientific article

A Functional Bioluminescent Zebrafish Screen for Enhancing Hematopoietic Cell Homing

scientific article published on 21 December 2016

A Model System for Visualization of Whole-Body Sdf-1 Expression During Hematopoietic Cell Transplant. ⬇️

scholarly article

A Novel Triple Umbilical Cord Blood Transplant (UCBT) Strategy To Promote NK Cell Immunotherapy (Unit 1) with a Fully Ablative Preparative Regimen Followed by a Double UCBT in Patients with Refractory AML. ⬇️

scholarly article

A Phase I study of granulocyte-macrophage-colony stimulating factor/interleukin-3 fusion protein (PIXY321) following ifosfamide, carboplatin, and etoposide therapy for children with recurrent or refractory solid tumors ⬇️

scientific article published on October 1, 1998

A Phase II Study Of Proteasome-Inhibition For Initial Therapy Of Chronic Graft-Versus-Host Disease ⬇️

scholarly article

A Randomized Trial of One Vs. Two Doses of Influenza Vaccine Following Allogeneic Transplantation ⬇️

scholarly article

A Refined Clinical Risk Score at Onset of Treatment for Acute Gvhd That Predicts Response to Initial Therapy, Survival and Transplant-Related Mortality ⬇️

scholarly article

A Selective and Potent Rock 2 Inhibitor (KD025) Decreases Human STAT3-Dependent IL-21 and IL-17 Production and Experimental Chronic Graft-Versus-Host Disease (cGVHD) ⬇️

scholarly article

A confirmation of chronic graft-versus-host disease prediction using allogeneic HY antibodies following sex-mismatched hematopoietic cell transplantation

scientific article published on 17 January 2019

A correlation between conditioning and engraftment in recipients of MHC-mismatched T cell-depleted murine bone marrow transplants

scientific article published on 01 August 1985

A critical role for CD48 antigen in regulating alloengraftment and lymphohematopoietic recovery after bone marrow transplantation

scientific article published on 01 December 1998

A critical role for donor-derived IL-22 in cutaneous chronic GVHD.

scientific article published on 23 September 2017

A murine cytokine fusion toxin specifically targeting the murine granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor on normal committed bone marrow progenitor cells and GM-CSF-dependent tumor cells ⬇️

scientific article published on October 1, 1995

A new murine model for bronchiolitis obliterans post-bone marrow transplant

scientific article

A novel approach to improve immune effector responses post transplant by restoration of CCL21 expression.

scientific article

A novel method for KIR-ligand typing by pyrosequencing to predict NK cell alloreactivity

scientific article

A novel system for simultaneous in vivo tracking and biological assessment of leukemia cells and ex vivo generated leukemia-reactive cytotoxic T cells

scientific article published in June 2004

A phase 2/3 multicenter randomized clinical trial of ABX-CBL versus ATG as secondary therapy for steroid-resistant acute graft-versus-host disease

scientific article

A phase I clinical, pharmacological, and biological trial of interleukin 6 plus granulocyte-colony stimulating factor after ifosfamide, carboplatin, and etoposide in children with recurrent/refractory solid tumors: enhanced hematological [...]

scientific article

A phase I/IB trial of murine monoclonal anti-GD2 antibody 14.G2a plus interleukin-2 in children with refractory neuroblastoma: a report of the Children's Cancer Group

scientific article published on July 1997

A phase II study of bortezomib plus prednisone for initial therapy of chronic graft-versus-host disease

scientific article published on 10 July 2014

A phase II trial of human recombinant interleukin-2 administered as a 4-day continuous infusion for children with refractory neuroblastoma, non-Hodgkin's lymphoma, sarcoma, renal cell carcinoma, and malignant melanoma. A Childrens Cancer Group study

scientific article published in June 1995

A picornaviral 2A-like sequence-based tricistronic vector allowing for high-level therapeutic gene expression coupled to a dual-reporter system

scientific article published on September 2005

A preclinical evaluation of Minnelide as a therapeutic agent against pancreatic cancer

scientific article published on October 2012

A randomized trial comparing prednisone with antithymocyte globulin/prednisone as an initial systemic therapy for moderately severe acute graft-versus-host disease

scientific article published in January 2000

A randomized trial of one versus two doses of influenza vaccine after allogeneic transplantation

scientific article published on 29 August 2012

A refined risk score for acute graft-versus-host disease that predicts response to initial therapy, survival, and transplant-related mortality

scientific article

A robust in vitro model for trans-lymphatic endothelial migration

scientific article

A substantial level of donor hematopoietic chimerism is required to protect donor-specific islet grafts in diabetic nod mice ⬇️

scientific article published on April 15, 2003

A trispecific killer engager molecule against CLEC12A effectively induces NK-cell mediated killing of AML cells

scientific article published on 23 October 2020

ARID5B regulates metabolic programming in human adaptive NK cells.

scientific article published on 30 July 2018

Abnormal T cell-dependent B-cell responses in SCID mice receiving allogeneic bone marrow in utero. Severe combined immune deficiency

scientific article published on 08 August 2002

Abnormal function of the bone marrow microenvironment in chronic myelogenous leukemia: role of malignant stromal macrophages.

scientific article

Absence of NKG2D ligands defines leukaemia stem cells and mediates their immune evasion

scientific article published on 17 July 2019

Absence of a facilitory role for NK 1.1-positive donor cells in engraftment across a major histocompatibility barrier in mice

scientific article published on 01 May 1988

Absence of host tumor necrosis factor receptor 1 attenuates manifestations of idiopathic pneumonia syndrome

scientific article published on 17 December 2004

Acceleration of idiopathic pneumonia syndrome (IPS) in the absence of donor MIP-1 alpha (CCL3) after allogeneic BMT in mice

scientific article

Achievement of Tolerance Induction to Prevent Acute Graft-vs.-Host Disease

article published in 2019

Acid sphingomyelinase deficiency does not protect from graft-versus-host disease in transplant recipients with Niemann-Pick disease

scientific article published on 01 January 2010

Activated Alveolar Macrophage-Derived Nitric Oxide Predicts the Development of Lung Damage After Marrow Transplantation in Mice

article

Activated Protein C (APC) Therapy Ameliorates Chronic Graft Versus Host Disease By Cell Signaling Mechanisms That Require Cleavage at Arg46 in PAR1 on T Cells ⬇️

scholarly article

Activated protein C ameliorates chronic graft-versus-host disease by PAR1-dependent biased cell signaling on T cells

scientific article published on 26 June 2019

Activation of p53 in Immature Myeloid Precursor Cells Controls Differentiation into Ly6c+CD103+ Monocytic Antigen-Presenting Cells in Tumors

scientific article published in January 2018

Activation of thymic regeneration in mice and humans following androgen blockade

scientific article

Acute Graft-Versus-Host Disease: Clinical Presentation and Response to Therapy Following Umbilical Cord Blood Transplant. ⬇️

scholarly article

Acute Graft-versus-Host Disease

scientific article published on 01 February 2018

Acute Graft-versus-Host Disease - Biologic Process, Prevention, and Therapy

scientific article published in November 2017

Acute graft-versus-host disease after unrelated donor umbilical cord blood transplantation: analysis of risk factors

scientific article

Acute graft-versus-host disease following unrelated donor marrow transplantation: failure of conventional therapy

scientific article published on July 1, 1992

Acute graft-versus-host disease is regulated by an IL-17-sensitive microbiome.

scientific article

Acute graft-versus-host disease: from the bench to the bedside

scientific article published on 27 August 2009

Acute toxicity of CD40 stimulation following syngeneic bone marrow transplantation ⬇️

scholarly article

Acute upper gastrointestinal graft-versus-host disease: clinical significance and response to immunosuppressive therapy.

scientific article published on August 1990

Adaptive NK Cells Resist Regulatory T-cell Suppression Driven by IL37.

scientific article published on 21 May 2018

Adaptive NK Cells with Low TIGIT Expression Are Inherently Resistant to Myeloid-Derived Suppressor Cells

scientific article published on 8 August 2016

Adaptive NK cell reconstitution is associated with better clinical outcomes

scholarly article by Frank Cichocki et al published 24 January 2019 in JCI insight

Adaptive Natural Killer Cell and Killer Cell Immunoglobulin-Like Receptor-Expressing T Cell Responses are Induced by Cytomegalovirus and Are Associated with Protection against Cytomegalovirus Reactivation after Allogeneic Donor Hematopoietic Cell Tr

scientific article

Adeno-associated virus-mediated delivery of a mutant endostatin in combination with carboplatin treatment inhibits orthotopic growth of ovarian cancer and improves long-term survival

scientific article published on April 2006

Adenosine receptor A2A deficiency in leukocytes increases arterial neointima formation in apolipoprotein E-deficient mice

scientific article

Adiposity As a Principal Component of Lethal Cytokine Storm Following Cancer Immunotherapy in Aged Mice ⬇️

scholarly article

Adiposity induces lethal cytokine storm after systemic administration of stimulatory immunotherapy regimens in aged mice

scientific article

Administration of either anti-CD40 or interleukin-12 following lethal total body irradiation induces acute lethal toxicity affecting the gut.

scientific article

Adoptive Transfer of Umbilical Cord Blood-Derived Regulatory T Cells and Early Viral Reactivation ⬇️

scientific article published on June 25, 2013

Adult bone marrow-derived pluripotent hematopoietic stem cells are engraftable when transferred in utero into moderately anemic fetal recipients.

scientific article published in February 1995

Advances and challenges in immunotherapy for solid organ and hematopoietic stem cell transplantation

scientific article published on March 2015

Advances in graft-versus-host disease biology and therapy ⬇️

scientific article published on May 11, 2012

Advances in targeting co-inhibitory and co-stimulatory pathways in transplantation settings: the Yin to the Yang of cancer immunotherapy

scientific article published on March 2017

Aging predisposes to acute inflammatory induced pathology after tumor immunotherapy

scientific article published on 30 September 2013

Allogeneic bone marrow transplantation for X-linked lymphoproliferative syndrome

scientific article published on 01 August 1986

Allogenic fetal liver cells have a distinct competitive engraftment advantage over adult bone marrow cells when infused into fetal as compared with adult severe combined immunodeficient recipients

scientific article published on 01 March 2002

Alpha phenyl-tert-butyl nitrone (PBN) protects syngeneic marrow transplant recipients from the lethal cytokine syndrome occurring after agonistic CD40 antibody administration

scientific article

Alteration of Tumor Metabolism by CD4+ T Cells Leads to TNF-α-Dependent Intensification of Oxidative Stress and Tumor Cell Death.

scientific article published on 7 June 2018

Altered B-cell homeostasis and excess BAFF in human chronic graft-versus-host disease

scientific article published on 23 January 2009

Altered T-cell receptor + CD28-mediated signaling and blocked cell cycle progression in interleukin 10 and transforming growth factor-beta-treated alloreactive T cells that do not induce graft-versus-host disease

scientific article

Alternate Donor HSCT for Fanconi Anemia (FA): Results of a Total Body Irradiation (TBI) Dose De-Escalation Study. ⬇️

scholarly article

Alternative Donor Hematopoietic Cell Transplantation In 94 Patients with Fanconi Anemia at the University of Minnesota ⬇️

scholarly article

Alternative donor hematopoietic cell transplantation for Fanconi anemia

scientific article published on 30 March 2015

Amelioration of epidermolysis bullosa by transfer of wild-type bone marrow cells

scientific article published on 27 October 2008

Amphiregulin in intestinal acute graft-versus-host disease: a possible diagnostic and prognostic aid

scientific article published on 13 November 2018

Amphiregulin modifies the Minnesota Acute Graft-versus-Host Disease Risk Score: results from BMT CTN 0302/0802

article

An aberrant NOTCH2-BCR signaling axis in B cells from patients with chronic GVHD.

scientific article published on 29 August 2017

An absence of CCR5 on donor cells results in acceleration of acute graft-vs-host disease

scientific article published in March 2004

An activated Th17-prone T cell subset involved in chronic graft-versus-host disease sensitive to pharmacological inhibition

scientific article

An alpha-defensin gene single nucleotide polymorphism modulates the gut microbiota and may alter the risk of acute graft-versus-host disease

scientific article published on 21 February 2020

An inherently bifunctional subset of Foxp3+ T helper cells is controlled by the transcription factor eos.

scientific article published on 16 May 2013

An irradiated marrow niche reveals a small non-collagenous protein mediator of homing, dermatopontin

scientific article published on 27 August 2021

Analysis of BMT CTN-0201 and -0901 samples did not reproduce the reported association between recipient REG3A rs7588571 and chronic GVHD

scientific article published on 31 August 2018

Analysis of the requirements for the induction of CD4+ T cell alloantigen hyporesponsiveness by ex vivo anti-CD40 ligand antibody

scientific article published on 01 January 2000

Analysis of the underlying cellular mechanisms of anti-CD154-induced graft tolerance: the interplay of clonal anergy and immune regulation

scientific article published in July 2005

Angiotensin receptor blockade mediated amelioration of mucopolysaccharidosis type I cardiac and craniofacial pathology

scientific article published on 14 October 2016

Anti-CD3 + IL-2-stimulated murine killer cells. In vitro generation and in vivo antitumor activity

scientific article published in February 1989

Anti-CD3 epsilon F(ab')2 fragments inhibit T cell expansion in vivo during graft-versus-host disease or the primary immune response to nominal antigen ⬇️

scientific article published on December 15, 1997

Anti-CD3 immunotoxin prevents low-dose STZ/interferon-induced autoimmune diabetes in mouse

scientific article published on 01 April 1992

Anti-graft-versus-host disease effect of DT390-anti-CD3sFv, a single-chain Fv fusion immunotoxin specifically targeting the CD3 epsilon moiety of the T-cell receptor.

scientific article

Antibodies targeting surface membrane antigens in patients with chronic graft-versus-host disease

scientific article published on 14 November 2017

Antibodies to CD40 induce a lethal cytokine cascade after syngeneic bone marrow transplantation

scientific article published in January 2001

Antitumor protection from the murine T-cell leukemia/lymphoma EL4 by the continuous subcutaneous coadministration of recombinant macrophage-colony stimulating factor and interleukin-2

scientific article published on 01 September 1993

Anti–PD-1 cancer immunotherapy induces central nervous system immune-related adverse events by microglia activation

scientific article published on 12 June 2024

Assessment of multi-organ system engraftment by genotypic typing using restriction fragment-length polymorphisms and by phenotypic typing using a microcytotoxicity assay

scientific article published on 01 November 1986

Association between recipient TNF rs361525 and acute GVHD: results from analysis of BMT CTN-0201 samples

scientific article published on 07 March 2018

Attenuation of acute graft-versus-host disease in the absence of the transcription factor RORγt

scientific article

Augmentation of antitumor effects by NK cell inhibitory receptor blockade in vitro and in vivo

scientific article published on 01 May 2001

Augmentation of donor bone marrow engraftment in histoincompatible murine recipients by granulocyte/macrophage colony-stimulating factor

scientific article published on 01 February 1988

Author Correction: Human in vitro-induced regulatory T cells display Dlgh1 dependent and PKC-θ restrained suppressive activity

scientific article published on 19 February 2020

Autologous bone marrow transplantation in acute myeloid leukemia: the University of Minnesota experience

scientific article published on 01 September 1996

Autologous bone marrow versus non-mobilized peripheral blood stem cell transplantation for lymphoid malignancies: a prospective, comparative trial

scientific article published on 01 March 1997

Autophagy-dependent regulatory T cells are critical for the control of graft-versus-host disease.

scientific article published on 22 September 2016

B Cells Drive Autoimmunity in Mice with CD28-Deficient Regulatory T Cells.

scientific article published in November 2017

B cell induction of IL-13 expression in NK cells: role of CD244 and SLAM-associated protein

scientific article published on 01 March 2006

B cells in chronic graft-versus-host disease

scientific article

B-cell targeting in chronic Graft-versus-Host disease

scientific article published in February 2018

B7 expression on T cells down-regulates immune responses through CTLA-4 ligation via T-T interactions [corrections].

scientific article published in January 2004

B7-1 expression decreases tumorigenicity and induces partial systemic immunity to murine neuroblastoma deficient in major histocompatibility complex and costimulatory molecules

scientific article published on 01 March 1995

B7-H3 expression in donor T cells and host cells negatively regulates acute graft-versus-host disease lethality

scientific article published on 26 March 2015

Base Editor Correction of COL7A1 in Recessive Dystrophic Epidermolysis Bullosa Patient-Derived Fibroblasts and iPSCs

scientific article published on 19 August 2019

Blockade of CD40 ligand-CD40 interaction impairs CD4+ T cell-mediated alloreactivity by inhibiting mature donor T cell expansion and function after bone marrow transplantation

scientific article published on 01 January 1997

Blockade of LIGHT/LTbeta and CD40 signaling induces allospecific T cell anergy, preventing graft-versus-host disease

scientific article

Blockade of programmed death-1 engagement accelerates graft-versus-host disease lethality by an IFN-gamma-dependent mechanism

scientific article

Blockade of the CD40/CD154 pathway enhances T-cell-depleted allogeneic bone marrow engraftment under nonmyeloablative and irradiation-free conditioning therapy

scientific article

Blocking IL-21 signaling ameliorates xenogeneic GVHD induced by human lymphocytes ⬇️

scientific article published on November 10, 2011

Bone Marrow Myeloid-Derived Suppressor Cells (MDSC) Inhibit Graft Versus Host Disease (GVHD) Via An Arginase-1 Dependant Mechanism That Is Upregulated by IL-13 ⬇️

scholarly article

Bone Marrow Regulatory T Cells Are a Unique Population, Supported by Niche-Specific Cytokines and Plasmacytoid Dendritic Cells, and Required for Chronic Graft-Versus-Host Disease Control

scientific article published on 22 September 2021

Bone marrow myeloid-derived suppressor cells (MDSCs) inhibit graft-versus-host disease (GVHD) via an arginase-1-dependent mechanism that is up-regulated by interleukin-13

scientific article

Bone marrow stromal and vascular smooth muscle cells have chemosensory capacity via bitter taste receptor expression

scientific article

Bone marrow transplantation and approaches to avoid graft-versus-host disease (GVHD).

scientific article

Bone marrow transplantation for recessive dystrophic epidermolysis bullosa

scientific article

Bortezomib-based graft-versus-host disease prophylaxis in HLA-mismatched unrelated donor transplantation

scientific article

Bortezomib-based immunosuppression after reduced-intensity conditioning hematopoietic stem cell transplantation: randomized phase II results

scientific article published on 11 January 2018

Busulfan disposition in children

scientific article published on 01 April 1990

Busulfan pharmacokinetics do not predict relapse in acute myeloid leukemia

scientific article published on 01 September 2000

Bystander activation and anti-tumor effects of CD8+ T cells following Interleukin-2 based immunotherapy is independent of CD4+ T cell help

scientific article

C5aR1 regulates T follicular helper differentiation and chronic graft-versus-host disease bronchiolitis obliterans

CC chemokine receptor 8 potentiates donor Treg survival and is critical for the prevention of murine graft-versus-host disease

scientific article published on 24 June 2013

CCR1 Is Required for Treg-Mediated Protection From Lethal Acute Graft-Versus-Host Disease. ⬇️

scholarly article

CD154 on the surface of CD4+CD25+ regulatory t cells contributes to skin transplant tolerance

scientific article published on 01 November 2003

CD16xCD33 bispecific killer cell engager (BiKE) activates NK cells against primary MDS and MDSC CD33+ targets

scientific article

CD28 blockade controls T cell activation to prevent graft-versus-host disease in primates

CD28 costimulation is essential for human T regulatory expansion and function

scientific article published on August 2008

CD28/B7 interactions are required for sustaining the graft-versus-leukemia effect of delayed post-bone marrow transplantation splenocyte infusion in murine recipients of myeloid or lymphoid leukemia cells ⬇️

scientific article published on 01 October 1997

CD30/CD30 ligand (CD153) interaction regulates CD4+ T cell-mediated graft-versus-host disease

scientific article published on 01 September 2004

CD4 T cell sphingosine 1-phosphate receptor (S1PR)1 and S1PR4 and endothelial S1PR2 regulate afferent lymphatic migration

scientific article published on 01 March 2019

CD4(+) T cells tolerized ex vivo to host alloantigen by anti-CD40 ligand (CD40L:CD154) antibody lose their graft-versus-host disease lethality capacity but retain nominal antigen responses ⬇️

scientific article published on August 1, 1998

CD4(+)CD25(+) immune regulatory cells are required for induction of tolerance to alloantigen via costimulatory blockade

scientific article

CD4+ and CD8+ T cells each can utilize a perforin-dependent pathway to mediate lethal graft-versus-host disease in major histocompatibility complex-disparate recipients ⬇️

scientific article published on August 27, 1997

CD4+CD25+ regulatory T-cell lines from human cord blood have functional and molecular properties of T-cell anergy

scientific article published on 14 July 2005

CD4+CD25+Foxp3+ Regulatory T Cell Function Outside the Immune System: Differential Regulation of Hematopoietic Progenitor Cell Populations. ⬇️

scholarly article

CD45-targeted antibody-drug-conjugate successfully conditions for allogeneic hematopoietic stem cell transplantation

CD47 (integrin-associated protein) engagement of dendritic cell and macrophage counterreceptors is required to prevent the clearance of donor lymphohematopoietic cells

scientific article

CD8-predominant T-cell CNS infiltration accompanies GVHD in primates and is improved with immunoprophylaxis

scientific article published on March 2014

CMV reactivation drives posttransplant T-cell reconstitution and results in defects in the underlying TCRβ repertoire

scientific article published on 7 April 2015

CRISPR/Cas9-Based Cellular Engineering for Targeted Gene Overexpression.

scientific article published on 22 March 2018

CRISPR/Cas9-based genetic correction for recessive dystrophic epidermolysis bullosa

scientific article published on 8 December 2016

CSF-1-dependant donor-derived macrophages mediate chronic graft-versus-host disease.

scientific article

Cadherin 17 mutation associated with leaky severe combined immune deficiency is corrected by HSCT

scientific article published on 23 October 2017

Cardiac disease in mucopolysaccharidosis type I attributed to catecholaminergic and hemodynamic deficiencies

scientific article

Cardiac functional and histopathologic findings in humans and mice with mucopolysaccharidosis type I: implications for assessment of therapeutic interventions in hurler syndrome

scientific article published on 02 December 2005

Caveolin-1 regulates TCR signal strength and regulatory T-cell differentiation into alloreactive T cells

scientific article published on 2 February 2016

Chemokine treatment rescues profound T-lineage progenitor homing defect after bone marrow transplant conditioning in mice

scientific article

Chemotherapy rescues tumor-driven aberrant CD4+ T-cell differentiation and restores an activated polyfunctional helper phenotype

scientific article

Chimeric Antigen Receptor T Cell-Mediated Neurotoxicity in Nonhuman Primates

scientific article published on 21 March 2018

Chimeric antigen receptor costimulation domains modulate human regulatory T cell function.

scientific article published on 14 March 2019

Chronic GvHD Is Characterized By Impaired B Cell Development in the Bone Marrow ⬇️

scholarly article

Chronic graft-versus-host disease: biological insights from preclinical and clinical studies

scientific article published on 7 November 2016

Chronic stimulation drives human NK cell dysfunction and epigenetic reprograming

scientific article published on 18 June 2019

Circulating T follicular helper cells with increased function during chronic graft-versus-host disease

scientific article published on 04 March 2016

Circulating angiogenic factors associated with response and survival in patients with acute graft-versus-host disease: results from Blood and Marrow Transplant Clinical Trials Network 0302 and 0802

scientific article published on 7 March 2015

Circulating macrophage colony-stimulating factor is not reduced in malignant osteopetrosis

scientific article published on 01 January 1992

Clearance of acute myeloid leukemia by haploidentical natural killer cells is improved using IL-2 diphtheria toxin fusion protein

scientific article

Clinical application of expanded CD4+25+ cells

scientific article

Clinical perspectives for regulatory T cells in transplantation tolerance ⬇️

scientific article published on 05 August 2011

Clinical-scale selection of anti-CD3/CD28-activated T cells after transduction with a retroviral vector expressing herpes simplex virus thymidine kinase and truncated nerve growth factor receptor

scientific article published on May 2002

Coblockade of the LFA1:ICAM and CD28/CTLA4:B7 pathways is a highly effective means of preventing acute lethal graft-versus-host disease induced by fully major histocompatibility complex-disparate donor grafts

scientific article published on 01 May 1995

Coexpression of Tim-3 and PD-1 identifies a CD8+ T-cell exhaustion phenotype in mice with disseminated acute myelogenous leukemia

scientific article

Combination graft-versus-host disease prophylaxis using immunotoxin (anti-CD5-RTA [Xomazyme-CD5]) plus methotrexate and cyclosporine or prednisone after unrelated donor marrow transplantation.

scientific article

Combination therapy using IL-2 and anti-CD25 results in augmented natural killer cell-mediated antitumor responses

scientific article published on October 2008

Combined OX40L and mTOR blockade controls effector T cell activation while preserving Treg reconstitution after transplant

scientific article published in September 2017

Combined effects of calcineurin inhibitors or sirolimus with anti-CD40L mAb on alloengraftment under nonmyeloablative conditions

scientific article published in November 2002

Comparative analysis of murine marrow-derived dendritic cells generated by Flt3L or GM-CSF/IL-4 and matured with immune stimulatory agents on the in vivo induction of antileukemia responses

scientific article published on 08 August 2002

Comparison of engraftment in recipients of matched sibling of unrelated donor marrow allografts

scientific article published on 01 January 1994

Comparison of enzymatic activity with evidence of engraftment in patients with inborn errors of metabolism receiving allogeneic marrow transplantation

scientific article published on 01 January 1986

Composite end point of graft-versus-host disease-free, relapse-free survival after allogeneic hematopoietic cell transplantation

scientific article

Concise review: Transplantation of human hematopoietic cells for extracellular matrix protein deficiency in epidermolysis bullosa

scientific article published on June 2011

Concise review: hitting the right spot with mesenchymal stromal cells

scientific article published on August 2010

Constitutively active Stat5b in CD4+ T cells inhibits graft-versus-host disease lethality associated with increased regulatory T-cell potency and decreased T effector cell responses

scientific article

Continuous IL-15 Signaling Leads to Functional Exhaustion of Human Natural Killer Cells through Metabolic Changes That Alters Their In Vivo Anti-Tumor Activity ⬇️

scholarly article

Continuous treatment with IL-15 exhausts human NK cells via a metabolic defect

scientific article published on 8 February 2018

Contrasting acute graft-versus-host disease effects of Tim-3/galectin-9 pathway blockade dependent upon the presence of donor regulatory T cells ⬇️

scientific article published on June 7, 2012

Control of acute myeloid leukemia relapse--dance between KIRs and HLA

scientific article published on 01 August 2012

Cooking Up Tolerance: Has a New Recipe Been Created? ⬇️

scientific article published on June 15, 2012

Coordinated acquisition of inhibitory and activating receptors and functional properties by developing human natural killer cells.

scientific article published on 10 August 2006

Cord blood CD4(+)CD25(+)-derived T regulatory cell lines express FoxP3 protein and manifest potent suppressor function

scientific article published on 16 September 2004

Correction of DNA protein kinase deficiency by spliceosome-mediated RNA trans-splicing and sleeping beauty transposon delivery

scientific article published on 24 April 2007

Correction of hemophilia as a proof of concept for treatment of monogenic diseases by fetal spleen transplantation

scholarly article

Correction of the Skin Defect in Murine Recessive Dystrophic Epidermolysis Bullosa by Bone Marrow Derived SLAM Family Receptor Enriched Cells. ⬇️

scholarly article

Correction: B Cells Drive Autoimmunity in Mice with CD28-Deficient Regulatory T Cells

scientific article published on 23 February 2018

Corruption of dendritic cell antigen presentation during acute GVHD leads to regulatory T-cell failure and chronic GVHD.

scientific article published on 23 June 2016

CpG oligodeoxynucleotides potentiate the antitumor effects of chemotherapy or tumor resection in an orthotopic murine model of rhabdomyosarcoma

scientific article published in August 2003

Critical role for CCR5 in the function of donor CD4+CD25+ regulatory T cells during acute graft-versus-host disease

scientific article published on 7 July 2005

Cryopreservation timing is a critical process parameter in a thymic regulatory T-cell therapy manufacturing protocol

scientific article published on 03 December 2019

Cutting Edge: TGF-β and Phosphatidylinositol 3-Kinase Signals Modulate Distinct Metabolism of Regulatory T Cell Subsets

scientific article published on 12 September 2018

Cutting edge: identification of autoreactive CD4+ and CD8+ T cell subsets resistant to PD-1 pathway blockade

scientific article

Cutting edge: sustained expansion of CD8+ T cells requires CD154 expression by Th cells in acute graft versus host disease

scientific article published on 01 April 1999

Cyclophosphamide prevents systemic keratinocyte growth factor-induced up-regulation of surfactant protein A after allogeneic transplant in mice

scientific article published on 01 November 2000

Cytokine and cytotoxic pathways of NK cell rejection of class I-deficient bone marrow grafts: influence of mouse colony environment.

scientific article

Cytokine expression in human cutaneous chronic graft-versus-host disease

scientific article published on 01 June 1996

Cytokine mediators of chronic graft-versus-host disease

scientific article published on 30 June 2017

Cytokine-primed bone marrow stem cells vs. peripheral blood stem cells for autologous transplantation: a randomized comparison of GM-CSF vs. G-CSF

scientific article published on 01 October 1997

Cytolytic CD4+ and CD8+ Regulatory T-Cells and Implications for Developing Immunotherapies to Combat Graft-Versus-Host Disease

scientific article published in 2022

Cytotoxic T cells reactive to an immunodominant leukemia-associated antigen can be specifically primed and expanded by combining a specific priming step with nonspecific large-scale expansion

scientific article

DNA Methylation Profile of Runx1 Regulatory Regions Is Correlated with Transition From Primitive to Definitive Hematopoietic Potential In Vitro and In Vivo ⬇️

scholarly article

DNA methylation of Runx1 regulatory regions correlates with transition from primitive to definitive hematopoietic potential in vitro and in vivo

scientific article published on 12 September 2013

Danger-associated extracellular ATP counters MDSC therapeutic efficacy in acute GVHD

scientific article published on 01 November 2019

Death Receptor 3 (DR3) Is Expressed By Innate Lymphoid Cells (ILC) and Ligation By Tumor Like Antigen-1 (TL1A) Leads To Costimulation and Significant ILC Expansion ⬇️

scholarly article

Defective Neo-Antigen Response to Keyhole Limpet Hemocyanin (KLH) Vaccines in Patients after Hematopoietic Cell Transplantation. ⬇️

scholarly article

Defining Successful Immune Reconstitution (IR) after Allogeneic Hematopoietic Cell Transplantation (HCT) ⬇️

scholarly article

Defining the Primate GvHD Transcriptome: Network Analysis Identifies the Key Pathways Responsible for GvHD Pathogenesis and the Mechanisms of Partial GvHD Control with Sirolimus ⬇️

scholarly article

Defining the Primate T Cell Transcriptome during Graft Versus Host Disease: New Data Implicating the Hedgehog and Aurora Kinase Pathways in Pathogenesis and Prevention ⬇️

scholarly article

Delayed immune reconstitution after allogeneic transplantation increases the risks of mortality and chronic GVHD

scientific article published on 01 April 2018

Delineation of antigen-specific and antigen-nonspecific CD8+ memory T-cell responses after cytokine-based cancer immunotherapy ⬇️

scientific article published on January 17, 2012

Delta-Like Notch Ligands Expressed By Host Non-Hematopoietic Radioresistant Cells Regulate Graft-Versus-Host Disease and Extrathymic T Cell Development After Bone Marrow Transplantation ⬇️

scholarly article

Delta-like Ligands Expressed By Stromal Cells in Secondary Lymphoid Organs Deliver an Early Pulse of Notch Signaling and Drive T Cell Pathogenicity in Acute Graft-Versus-Host Disease ⬇️

scholarly article

Dendritic Cell Expression of Retinal Aldehyde Dehydrogenase-2 Controls Graft-versus-Host Disease Lethality

scientific article published on 18 March 2019

Dendritic cell programming by cytomegalovirus stunts naive T cell responses via the PD-L1/PD-1 pathway.

scientific article

Dendritic cells pulsed or fused with AML cellular antigen provide comparable in vivo antitumor protective responses

scientific article published on October 2006

Dependency on intercellular adhesion molecule recognition and local interleukin-2 provision in generation of an in vivo CD8+ T-cell immune response to murine myeloid leukemia

scientific article published on 01 May 1995

Depletion of endogenous tumor-associated regulatory T cells improves the efficacy of adoptive cytotoxic T-cell immunotherapy in murine acute myeloid leukemia

scientific article published on September 2009

Depressed leukocyte reconstitution and engraftment in murine recipients of T cell-depleted histoincompatible marrow pretreated with interleukin 3

scientific article published on 01 October 1988

Despite high levels of expression in thymic epithelial cells, miR-181a1 and miR-181b1 are not required for thymic development.

scientific article published on 27 June 2018

Development of IL-22-producing NK lineage cells from umbilical cord blood hematopoietic stem cells in the absence of secondary lymphoid tissue

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Development of a decellularized lung bioreactor system for bioengineering the lung: the matrix reloaded

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Differential Regulation of T-cell Immunity and Tolerance by Stromal Laminin Expressed in the Lymph Node

scientific article published on 01 October 2019

Differential effects of 2-deoxy-D-glucose on in vitro expanded human regulatory T cell subsets

scientific article published on 06 June 2019

Differential effects of proteasome inhibition by bortezomib on murine acute graft-versus-host disease (GVHD): delayed administration of bortezomib results in increased GVHD-dependent gastrointestinal toxicity

scientific article published on 16 June 2005

Differential effects of the absence of interferon-gamma and IL-4 in acute graft-versus-host disease after allogeneic bone marrow transplantation in mice ⬇️

scientific article published on November 1, 1998

Differential phenotypes of memory CD4 and CD8 T cells in the spleen and peripheral tissues following immunostimulatory therapy

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Differential roles for CCR5 expression on donor T cells during graft-versus-host disease based on pretransplant conditioning

scientific article published in July 2004

Difficult stem cell mobilization despite adequate CD34+ cell dose predicts shortened progression free and overall survival after autologous HSCT for lymphoma

scientific article published on 28 May 2007

Diminished neo-antigen response to keyhole limpet hemocyanin (KLH) vaccines in patients after treatment with chemotherapy or hematopoietic cell transplantation

scientific article published on 19 August 2005

Disruption of HIV-1 co-receptors CCR5 and CXCR4 in primary human T cells and hematopoietic stem and progenitor cells using base editing

Dissecting the biology of allogeneic HSCT to enhance the GvT effect whilst minimizing GvHD

scientific article published on 20 April 2020

Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism

scientific article published on 01 November 2018

Distinct Regulatory and Effector T Cell Metabolic Demands during Graft-Versus-Host Disease

scientific article published on 30 November 2019

Distinct roles for donor- and host-derived antigen-presenting cells and costimulatory molecules in murine chronic graft-versus-host disease: requirements depend on target organ

scientific article published on 02 November 2004

Divergent fates of antigen-specific CD8<sup>+</sup> T cell clones in mice with acute leukemia

scientific article published on 01 November 2021

Donor B-cell alloantibody deposition and germinal center formation are required for the development of murine chronic GVHD and bronchiolitis obliterans

scientific article published on 9 November 2011

Donor CD4+ Foxp3+ regulatory T cells are necessary for posttransplantation cyclophosphamide-mediated protection against GVHD in mice

scientific article

Donor T Cells Require Notch Signals but Not Alloantigen Presentation from Specialized Secondary Lymphoid Organ Fibroblasts to Drive Graft-Versus-Host Disease ⬇️

scholarly article

Donor T cells primed on leukemia lysate-pulsed recipient APCs mediate strong graft-versus-leukemia effects across MHC barriers in full chimeras.

scientific article published on 30 January 2009

Donor and host B7-H4 expression negatively regulates acute graft-versus-host disease lethality

scientific article published on 03 October 2019

Donor and host influences in bone marrow transplantation for immunodeficiency disease and leukemia

scientific article published on October 1993

Donor and recipient plasma follistatin levels are associated with acute GvHD in Blood and Marrow Transplant Clinical Trials Network 0402.

scientific article

Donor chimerism does not predict response to donor lymphocyte infusion for relapsed chronic myelogenous leukemia after allogeneic hematopoietic cell transplantation

scientific article published in March 2004

Dose and timing of interleukin (IL)-12 and timing and type of total-body irradiation: effects on graft-vs.-host disease inhibition and toxicity of exogenous IL-12 in murine bone marrow transplant recipients

scientific article published on 01 January 1999

Dose-escalated interleukin-2 therapy for refractory chronic graft-versus-host disease in adults and children

scientific article published on 01 September 2019

Dynamic Graft-versus-Host Disease-Free, Relapse-Free Survival: Multistate Modeling of the Morbidity and Mortality of Allotransplantation

scientific article published on 22 May 2019

Early E. casseliflavus gut colonization and outcomes of allogeneic hematopoietic cell transplantation

scientific article published on 08 August 2019

Early Notch Signals Induce a Pathogenic Molecular Signature during Priming of Alloantigen-Specific Conventional CD4+ T Cells in Graft-versus-Host Disease

scientific article published on 10 June 2019

Early antithymocyte globulin therapy improves survival in patients with steroid-resistant acute graft-versus-host disease

scientific article published in January 2002

Effect of IL-7 or IL-4 on reconstitution of donor lymphoid cells in congenic murine bone marrow transplantation

scientific article published on 01 July 1995

Effect of radiation dose-rate on hematopoietic cell engraftment in adult zebrafish

scientific article

Effect of recombinant human macrophage colony-stimulating factor in irradiated murine recipients of T-cell-depleted allogeneic or non-depleted syngeneic bone marrow transplants ⬇️

scientific article published on March 15, 1992

Effect of tumor necrosis factor alpha and of the soluble tumor necrosis factor receptor on insulin secretion of isolated islets of Langerhans

scientific article published on 01 December 1992

Effective Multi-lineage Engraftment in a Mouse Model of Fanconi Anemia Using Non-genotoxic Antibody-Based Conditioning

scientific article published on 08 February 2020

Effective immunization against neuroblastoma using double-transduced tumor cells secreting GM-CSF and interferon-gamma

scientific article published on 01 March 1996

Effector CD4+ T cells, the cytokines they generate, and GVHD: something old and something new.

scientific article

Effector cells derived from host CD8 memory T cells mediate rapid resistance against minor histocompatibility antigen-mismatched allogeneic marrow grafts without participation of perforin, Fas ligand, and the simultaneous inhibition of 3 tumor necro

scientific article

Effects of MicroRNA on Regulatory T Cells and Implications for Adoptive Cellular Therapy to Ameliorate Graft-versus-Host Disease

scientific article published on 31 January 2018

Effects of donor T-cell trafficking and priming site on graft-versus-host disease induction by naive and memory phenotype CD4 T cells

scientific article published on 19 February 2008

Effects of oxidant stress on inflammation and survival of iNOS knockout mice after marrow transplantation

scientific article

Efficacy and immunologic effects of extracorporeal photopheresis plus interleukin-2 in chronic graft-versus-host disease

article published in 2019

Efficacy, durability, and response predictors of low-dose interleukin-2 therapy for chronic graft-versus-host disease

scientific article published on 12 April 2016

Elevation of intracellular cyclic AMP in alloreactive CD4(+) T Cells induces alloantigen-specific tolerance that can prevent GVHD lethality in vivo

scientific article published in May 2007

Embryonic pig pancreatic tissue transplantation for the treatment of diabetes

scientific article (publication date: July 2006)

Emerging strategies to boost thymic function

scientific article

Endogenous IL-2 production by natural killer cells maintains cytotoxic and proliferative capacity following retroviral-mediated gene transfer

scientific article published on 01 October 1997

Endothelial cell expression of tissue factor in sickle mice is augmented by hypoxia/reoxygenation and inhibited by lovastatin

scientific article published on 8 April 2004

Engineered IL-2 Cytokine-Cytokine Receptor Complex Enables Selective Expansion of Regulatory T Cells and Facilitates Establishment of Organ Transplantation Tolerance ⬇️

scholarly article

Engineering lymphocyte subsets: tools, trials and tribulations

scientific article

Engraftment of severe combined immune deficient mice receiving allogeneic bone marrow via In utero or postnatal transfer.

scientific article

Enhanced survival but reduced engraftment in murine recipients of recombinant granulocyte/macrophage colony-stimulating factor following transplantation of T-cell-depleted histoincompatible bone marrow

scientific article published on 01 October 1988

Eomesodermin promotes the development of type 1 regulatory T (TR1) cells.

scientific article

Epstein-Barr virus associated B cell lymphoproliferative disorders following bone marrow transplantation

scientific article

Erratum: Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells

scientific article published on 01 April 2018

Erythropoietin Receptor-Mediated Molecular Crosstalk Promotes T Cell Immunoregulation and Transplant Survival

scientific article published on 16 March 2017

Evaluation of KIR ligand incompatibility in mismatched unrelated donor hematopoietic transplants. Killer immunoglobulin-like receptor

scientific article published on 05 July 2002

Evaluation of TCR Gene Editing Achieved by TALENs, CRISPR/Cas9, and megaTAL Nucleases

scientific article published on 27 October 2015

Evaluation of innate and adaptive immunity contributing to the antitumor effects of PD1 blockade in an orthotopic murine model of pancreatic cancer

scientific article published on 16 March 2016

Evidence for early fibrosis and increased airway resistance in bone marrow transplant recipient mice deficient in MMP12.

scientific article

Ex vivo depletion of alloreactive cells based on CFSE dye dilution, activation antigen selection, and dendritic cell stimulation ⬇️

scientific article published on 02 October 2003

Ex vivo fucosylation of third-party human regulatory T cells enhances anti-graft-versus-host disease potency in vivo

scientific article

Ex vivo inhibition of NF-kappaB signaling in alloreactive T-cells prevents graft-versus-host disease.

scientific article published on March 2009

Expanded nonhuman primate tregs exhibit a unique gene expression signature and potently downregulate alloimmune responses

scientific article

Expansion and homing of adoptively transferred human natural killer cells in immunodeficient mice varies with product preparation and in vivo cytokine administration: implications for clinical therapy

scientific article

Expression of telomerase and telomere length are unaffected by either age or limb regeneration in Danio rerio

scientific article

Exuberant inflammation in nicotinamide adenine dinucleotide phosphate-oxidase-deficient mice after allogeneic marrow transplantation

scientific article published in June 2002

FK506 (Tacrolimus) monotherapy for prevention of graft-versus-host disease after histocompatible sibling allogenic bone marrow transplantation.

scientific article published on April 1996

FK506 inhibits graft-versus-host disease and bone marrow graft rejection in murine recipients of MHC disparate donor grafts by interfering with mature peripheral T cell expansion post-transplantation

scientific article published on 01 August 1994

FLT3 ligand administration after hematopoietic cell transplantation increases circulating dendritic cell precursors that can be activated by CpG oligodeoxynucleotides to enhance T-cell and natural killer cell function

scientific article published on 01 January 2005

FTY720 Markedly Increases Alloengraftment but Does Not Eliminate Host Anti-Donor T Cells that Cause Graft Rejection on Its Withdrawal ⬇️

scientific article published on June 19, 2012

FTY720 Promotes Engraftment of Allogeneic Donor Bone Marrow Stem Cells but Impairs Thymopoiesis Resulting in Delayed Graft Rejection. ⬇️

scholarly article

Facilitating resolution of life-threatening acute GVHD with human chorionic gonadotropin and epidermal growth factor

scientific article published on 01 April 2020

Factors affecting thymic function after allogeneic hematopoietic stem cell transplantation

scientific article published on 01 March 2001

Factors predicting single-unit predominance after double umbilical cord blood transplantation ⬇️

scientific article published on September 26, 2011

Fanconi anemia gene editing by the CRISPR/Cas9 system

scientific article

Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands

scientific article published on 20 March 2017

First Use of Allogeneic Stem Cells in the Treatment of Recessive Dystrophic Epidermolysis Bullosa: Demonstration of Biochemical and Clinical Improvement. ⬇️

scholarly article

First-in-human Phase 1 Clinical Study of the IL-15 Superagonist Complex ALT-803 to Treat Relapse after Transplantation

scientific article published on 20 February 2018

First-in-human trial of rhIL-15 and haploidentical natural killer cell therapy for advanced acute myeloid leukemia

scientific article published on 01 July 2019

Flt3 ligand (FL) treatment of murine donors does not modify graft-versus-host disease (GVHD) but FL treatment of recipients post-bone marrow transplantation accelerates GVHD lethality

scientific article published on 01 January 2001

Flt3 ligand antitumor activity in a murine breast cancer model: a comparison with granulocyte-macrophage colony-stimulating factor and a potential mechanism of action

scientific article published on September 1999

Fludarabine vs cladribine plus busulfan and low-dose TBI as reduced intensity conditioning for allogeneic hematopoietic stem cell transplantation: a prospective randomized trial

scientific article published on 15 January 2007

Follicular regulatory T cells control humoral and allergic immunity by restraining early B cell responses

scientific article published on 02 September 2019

Follistatin and Soluble Endoglin Predict 1-Year Nonrelapse Mortality after Allogeneic Hematopoietic Cell Transplantation

scientific article published on 10 November 2019

FoxP3 and Ezh2 regulate Tfr cell suppressive function and transcriptional program

scientific article published on 31 January 2019

Functional NK cell repertoires are maintained through IL-2Rα and Fas ligand.

scientific article published on 14 March 2014

GCNT1-Mediated O-Glycosylation of the Sialomucin CD43 Is a Sensitive Indicator of Notch Signaling in Activated T Cells

scientific article published on 14 February 2020

GM-CSF-induced internal autocrine proliferation occurs in a compartment outside of the endoplasmic reticulum

scientific article published on July 1, 1995

GSK 3 inhibition drives maturation of NK cells and enhances their antitumor activity

scientific article published on 8 August 2017

GVHD after haploidentical transplantation: a novel, MHC-defined rhesus macaque model identifies CD28− CD8+ T cells as a reservoir of breakthrough T-cell proliferation during costimulation blockade and sirolimus-based immunosuppression ⬇️

scientific article published on September 10, 2010

GVHD prevents NK-cell-dependent leukemia and virus-specific innate immunity.

scientific article published on 07 December 2016

GVHD-associated, inflammasome-mediated loss of function in adoptively transferred myeloid-derived suppressor cells.

scientific article

Gastrointestinal cells of IL-7 receptor null mice exhibit increased sensitivity to irradiation

scientific article published on 01 March 2001

Gender-related dimorphism in aortic insufficiency in murine mucopolysaccharidosis type I

scientific article

Gene therapy of murine solid tumors with T cells transduced with a retroviral vascular endothelial growth factor--immunotoxin target gene

scientific article published on March 2002

General strategies in in vivo animal modeling

scientific article published on January 1, 1992

Generation and function of progenitor T cells from StemRegenin-1-expanded CD34+ human hematopoietic progenitor cells

scientific article published on 01 October 2019

Generation and large-scale expansion of human inducible regulatory T cells that suppress graft-versus-host disease

scientific article published on 12 May 2011

Genetic trickery--escape of leukemia from immune attack

scientific article published on 01 July 2009

Germinal Center Generation and Maintenance By T Follicular Helper Cells Is Required For The Development Of Chronic Gvhd Associated Bronchiolitis Obliterans In a Preclinical Model ⬇️

scholarly article

Glucagon like peptide-2 for Intestinal stem cell and Paneth cell repair during graft-versus-host disease in mice and humans

scientific article published on 15 June 2020

Graft Versus Host Disease After Liver Transplantation in Adults: A Case series, Review of Literature, and an Approach to Management

scientific article

Graft-versus-host disease of the CNS is mediated by TNF upregulation in microglia

scientific article published on 01 March 2020

Graft-versus-host disease prevention in allogeneic bone marrow transplantation from histocompatible siblings. A pilot study using immunotoxins for T cell depletion of donor bone marrow

scientific article published on 01 July 1987

GvHD After Haploidentical Transplant: A Novel, MHC-Defined Rhesus Macaque Model Identifies CD28-Negative CD8+ T Cells as a Reservoir of Breakthrough T Cell Proliferation During Costimulation Blockade and Sirolimus-Based Immunosuppression ⬇️

scholarly article

Haploidentical Natural Killer (NK) Cells Expanding In Vivo After Adoptive Transfer Exhibit Hyperfunction That Partially Overcomes Self Tolerance and Leads to Clearance of Refractory Leukemia ⬇️

scholarly article

Haploidentical Natural Killer Cell Infusion Induces Remission in Non-Hodgkin Lymphoma and Overcomes Resistance to Rituximab ⬇️

scholarly article

Haploidentical natural killer cells induce remissions in non-Hodgkin lymphoma patients with low levels of immune-suppressor cells

scientific article

Helminth-Induced Production of TGF-β and Suppression of Graft-versus-Host Disease Is Dependent on IL-4 Production by Host Cells

article

Hematopoietic cell therapy for metabolic disease

scientific article published on October 2007

Hematopoietic differentiation of induced pluripotent stem cells from patients with mucopolysaccharidosis type I (Hurler syndrome)

scientific article

Hematopoietic progenitor cell regulation by CD4+CD25+ T cells

scientific article

Hematopoietic reconstitution by multipotent adult progenitor cells: precursors to long-term hematopoietic stem cells

scientific article

Hematopoietic reconstitution by multipotent adult progenitor cells: precursors to long-term hematopoietic stem cells.

scientific article

High levels of peroxynitrite are generated in the lungs of irradiated mice given cyclophosphamide and allogeneic T cells. A potential mechanism of injury after marrow transplantation

scientific article published on 01 June 1999

Higher therapeutic CsA levels early post transplantation reduce risk of acute GVHD and improves survival

scientific article published on 16 September 2013

Histone Deacetylase 11 (HDAC11) Is a Regulatory Checkpoint of T-Cell Function: Implications for T-Cell Adoptive Immunotherapy ⬇️

scholarly article

Homeostatic expansion occurs independently of costimulatory signals

scientific article published on 01 November 2001

Host T cells resist graft-versus-host disease mediated by donor leukocyte infusions

scientific article published on 01 November 2000

Host factors that impact the biodistribution and persistence of multipotent adult progenitor cells

scientific article published on 12 January 2006

Host programmed death ligand 1 is dominant over programmed death ligand 2 expression in regulating graft-versus-host disease lethality

scientific article published on 12 September 2013

How ibrutinib, a B-cell malignancy drug, became an FDA-approved second-line therapy for steroid-resistant chronic GVHD

scientific article published on 01 August 2018

Human CD19-Targeted Mouse T Cells Induce B Cell Aplasia and Toxicity in Human CD19 Transgenic Mice

scientific article published on 07 April 2018

Human CD34(+) bone marrow cells regulate stromal production of interleukin-6 and granulocyte colony-stimulating factor and increase the colony-stimulating activity of stroma ⬇️

scientific article published on May 15, 1998

Human Effectors of Acute and Chronic GVHD Overexpress CD83 and Predict Mortality

scientific article published in 2023

Human T regulatory cell therapy: take a billion or so and call me in the morning

scientific article

Human group3 innate lymphoid cells express DR3 and respond to TL1A with enhanced IL-22 production and IL-2-dependent proliferation

scientific article

Human in vitro-induced regulatory T cells display Dlgh1dependent and PKC-θ restrained suppressive activity

scientific article published on 26 June 2017

Human plasmacytoid dendritic cells activated by CpG oligodeoxynucleotides induce the generation of CD4+CD25+ regulatory T cells

scientific article

Human surfactant protein a suppresses T cell-dependent inflammation and attenuates the manifestations of idiopathic pneumonia syndrome in mice

scientific article

ICOSL+ plasmacytoid dendritic cells as inducer of graft-versus-host disease, responsive to a dual ICOS/CD28 antagonist

scientific article published on 01 October 2020

IDO in human gut graft-versus-host disease

scientific article published on 9 August 2011

IFN-gamma mediates CD4+ T-cell loss and impairs secondary antitumor responses after successful initial immunotherapy

scientific article

IFN-γ receptor-deficient donor T cells mediate protection from graft-versus-host disease and preserve graft-versus-tumor responses after allogeneic bone marrow transplantation.

scientific article

IL-10 and TGF-beta induce alloreactive CD4+CD25- T cells to acquire regulatory cell function

scientific article published on 27 February 2003

IL-15 administration following syngeneic bone marrow transplantation prolongs survival of lymphoma bearing mice

scientific article published on 01 September 1996

IL-2 + Anti-IL2 Complex in Situ Stimulation of Host Tregs Combined with Absence of Donor B7.1 / B7.2: A Novel Approach to Facilitate Chimerism in RIC MHC-Matched Miha-Mismatched BMT Recipients. ⬇️

scholarly article

IL-2 Stimulated Treg Inhibit in Vitro Expansion of Haploidentical Natural Killer (NK) Cells, Which Is Partially Overcome with An IL-2-Diphtheria Toxin Fusion Protein In Vivo, ⬇️

scholarly article

IL-2 enhances ex vivo-expanded regulatory T-cell persistence after adoptive transfer

scientific article published on 01 April 2020

IL-2 receptor beta-dependent STAT5 activation is required for the development of Foxp3+ regulatory T cells

scientific article published in January 2007

IL-2-based immunotherapy after autologous transplantation for lymphoma and breast cancer induces immune activation and cytokine release: a phase I/II trial

scientific article

IL-21 blockade reduces graft-versus-host disease mortality by supporting inducible T regulatory cell generation

scientific article published on 20 October 2009

IL-22 Is Critical To The Pathogenesis Of Cutaneous Gvhd Mediated By Th17 Cells ⬇️

scholarly article

IL-33 is an unconventional Alarmin that stimulates IL-2 secretion by dendritic cells to selectively expand IL-33R/ST2+ regulatory T cells

scientific article

IL-7 signaling imparts polyfunctionality and stemness potential to CD4(+) T cells.

scientific article published on 25 April 2016

IL15 Trispecific Killer Engagers (TriKE) Make Natural Killer Cells Specific to CD33+ Targets While Also Inducing Persistence, In Vivo Expansion, and Enhanced Function

scientific article published on 4 February 2016

Ibrutinib for chronic graft-versus-host disease after failure of prior therapy

scientific article published on 18 September 2017

Ibrutinib treatment ameliorates murine chronic graft-versus-host disease

scientific article

Identification of Cellular Sources of IL-2 Needed for Regulatory T Cell Development and Homeostasis

scientific article published on 04 May 2018

Identification of transfused blood cells in children with severe combined immunodeficiency syndrome by analysis of multiple cell lineages using restriction fragment length polymorphisms

scientific article published on 01 May 1990

Immune Reconstitution (IR) after Allogeneic Hematopoietic Cell Transplantation (alloHCT): Comparing Results in Recipients of Unrelated Umbilical Cord Blood (UCB) to Those with an HLA-Matched Sibling Donor Peripheral Blood (MSD PB) ⬇️

scholarly article

Immune Reconstitution after Umbilical Cord Blood Versus Peripheral Blood Progenitor Cell Transplantation in Adults Following Myeloablative Conditioning ⬇️

scholarly article

Immune regulatory cell infusion for graft-versus-host disease prevention and therapy.

scientific article published on 4 May 2018

Immune regulatory cells in umbilical cord blood: T regulatory cells and mesenchymal stromal cells

scientific article published on October 2009

Immunobiology of allogeneic hematopoietic stem cell transplantation

scientific article published on January 2007

Immunosuppressive myeloid cells induced by chemotherapy attenuate antitumor CD4+ T-cell responses through the PD-1-PD-L1 axis

scientific article

Impact of ABO-mismatch on risk of GVHD after umbilical cord blood transplantation ⬇️

scientific article published on February 18, 2013

Impact of Allele-Level HLA Mismatch on Outcomes in Recipients of Double Umbilical Cord Blood Transplantation

scientific article published on 29 September 2015

Impact of Graft Source on Immune Recovery: Comparions Between Unrelated Umbilical Cord Blood (UCB), HLA Matched Sibling (Sib) Donor and Autologous (Auto) Hematopoietic Stem Cells. ⬇️

scholarly article

Impaired bone marrow B-cell development in mice with a bronchiolitis obliterans model of cGVHD

article

Improved graft-versus-host disease-free, relapse-free survival associated with bone marrow as the stem cell source in adults

scientific article published on April 2016

Improved survival and leukocyte reconstitution without detrimental effects on engraftment in murine recipients of human recombinant granulocyte colony-stimulating factor after transplantation of T-cell-depleted histoincompatible bone marrow

scientific article published on 01 November 1989

In Vitro Generation of NK22 Cells From Hematopoietic Stem Cells ⬇️

scholarly article

In Vitro Induction of Human Regulatory T Cells Using Conditions of Low Tryptophan Plus Kynurenines

scientific article

In Vitro T-Cell Generation From Adult, Embryonic, and Induced Pluripotent Stem Cells: Many Roads to One Destination

scientific article (publication date: November 2015)

In situ identification of allospecific B cells using pentamers

scientific article

In utero engraftment of fully H-2-incompatible versus congenic adult bone marrow transferred into nonanemic or anemic murine fetal recipients.

scientific article published on September 1993

In utero transfer of adult bone marrow cells into recipients with severe combined immunodeficiency disorder yields lymphoid progeny with T- and B-cell functional capabilities

scientific article published on 01 December 1995

In vitro functional correction of the mutation responsible for murine severe combined immune deficiency by small fragment homologous replacement

scientific article

In vitro tumor-pulsed or in vivo Flt3 ligand-generated dendritic cells provide protection against acute myelogenous leukemia in nontransplanted or syngeneic bone marrow-transplanted mice

scientific article published on 01 March 2001

In vitro-differentiated TH17 cells mediate lethal acute graft-versus-host disease with severe cutaneous and pulmonary pathologic manifestations

scientific article published on 28 October 2008

In vitro-expanded human CD4(+)CD25(+) T-regulatory cells can markedly inhibit allogeneic dendritic cell-stimulated MLR cultures

scientific article published on 18 March 2004

In vivo T-cell receptor ligation facilitates alloengraftment and prevents lethal graft-versus-host disease (GVHD) in mice

scientific article published on 01 January 1993

In vivo administration of anti-CD3 monoclonal antibodies or immunotoxins in murine recipients of allogeneic T cell-depleted marrow for the promotion of engraftment ⬇️

scientific article published on 01 September 1991

In vivo administration of recombinant human granulocyte/macrophage colony-stimulating factor in acute lymphoblastic leukemia patients receiving purged autografts.

scientific article

In vivo blockade of CD28/CTLA4: B7/BB1 interaction with CTLA4-Ig reduces lethal murine graft-versus-host disease across the major histocompatibility complex barrier in mice

scientific article published on 01 June 1994

In vivo imaging of graft-versus-host-disease in mice

scientific article published on 8 January 2004

In vivo inhibition of cytokine responsiveness and graft-versus-host disease mortality by rapamycin leads to a clinical-pathological syndrome discrete from that observed with cyclosporin A

scientific article published on 01 May 1996

In vivo or in vitro anti-CD3 epsilon chain monoclonal antibody therapy for the prevention of lethal murine graft-versus-host disease across the major histocompatibility barrier in mice.

scientific article published on April 1994

In vivo survival and homeostatic proliferation of natural killer cells.

scientific article

Inactivation of the adenosine A2A receptor protects apolipoprotein E-deficient mice from atherosclerosis

scientific article

Increased Effector Memory Insulin-Specific CD4+ T Cells Correlate With Insulin Autoantibodies in Patients With Recent-Onset Type 1 Diabetes.

scientific article published on 25 August 2017

Increased T follicular helper cells and germinal center B cells are required for cGVHD and bronchiolitis obliterans

scientific article

Increased mitochondrial apoptotic priming of human regulatory T cells after allogeneic hematopoietic stem cell transplantation.

scientific article

Increasing Regulatory T Cells With Interleukin-2 and Interleukin-2 Antibody Complexes Attenuates Lung Inflammation and Heart Failure Progression

scientific article published on 09 May 2016

Indoleamine 2,3-dioxygenase is a critical regulator of acute graft-versus-host disease lethality

scientific journal article

Induced pluripotent stem cells from individuals with recessive dystrophic epidermolysis bullosa

scientific article

Inducing the tryptophan catabolic pathway, indoleamine 2,3-dioxygenase (IDO), for suppression of graft-versus-host disease (GVHD) lethality

scientific article published on 14 October 2009

Induction of CD4+ T cell alloantigen-specific hyporesponsiveness by IL-10 and TGF-beta

scientific article published on 01 October 1999

Induction of immunosuppressive functions and NF-κB by FLIP in monocytes

scientific article published in Nature Communications

Induction of monocyte- and T-cell-attracting chemokines in the lung during the generation of idiopathic pneumonia syndrome following allogeneic murine bone marrow transplantation

scientific article published on 01 August 2000

Induction of transplantation tolerance by combining non-myeloablative conditioning with delivery of alloantigen by T cells

scientific article published on 15 February 2008

Inflammasome effects in GvHD

scientific article published on 11 November 2015

Inflammatory cytokines and the development of pulmonary complications after allogeneic hematopoietic cell transplantation in patients with inherited metabolic storage disorders

scientific article

Influenza infection results in local expansion of memory CD8(+) T cells with antigen non-specific phenotype and function.

scientific article published on January 2014

Infusion of Ex Vivo Activated Donor Type 2 Innate Lymphoid Cells Inhibit Th1 Activity and Reduces Acute Graft-Versus-Host Disease ⬇️

scholarly article

Infusion of anti-B7.1 (CD80) and anti-B7.2 (CD86) monoclonal antibodies inhibits murine graft-versus-host disease lethality in part via direct effects on CD4+ and CD8+ T cells

scientific article published on 01 October 1996

Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics ⬇️

scientific article published on October 15, 2010

Infusions of interleukin-1 alpha after autologous transplantation for Hodgkin's disease and non-Hodgkin's lymphoma induce effector cells with antilymphoma cytolytic activity

scientific article published on 01 May 1994

Inhibiting retinoic acid signaling ameliorates graft-versus-host disease by modifying T-cell differentiation and intestinal migration

scientific article published on 27 June 2013

Inhibition of Human Dendritic Cell ER Stress Response Reduces T Cell Alloreactivity Yet Spares Donor Anti-tumor Immunity

scientific article published on 06 December 2018

Inhibition of acute graft-versus-host disease with retention of graft-versus-tumor effects by the proteasome inhibitor bortezomib

scientific article

Inhibition of inositol kinase B controls acute and chronic graft-versus-host disease

scientific article published on 01 January 2020

Inhibition of pancreatic islet beta cell function by tumor necrosis factor is blocked by a soluble tumor necrosis factor receptor

scientific article published on 01 February 1993

Insights into the mechanism of FTY720 and compatibility with regulatory T cells for the inhibition of graft-versus-host disease (GVHD).

scientific article

Interactions of keratinocyte growth factor with a nitrating species after marrow transplantation in mice

scientific article published on 01 August 1999

Intercellular adhesion molecule-I (ICAM-I, CD54) deficiency segregates the unique pathophysiological requirements for generating idiopathic pneumonia syndrome (IPS) versus graft-versus-host disease following allogeneic murine bone marrow transplanta

scientific article published on 01 January 2001

Interleukin 2 immediately after autologous bone marrow transplantation for acute lymphoblastic leukemia--a phase I study

scientific article published on January 1993

Interleukin-1 alpha administered after autologous transplantation: a phase I/II clinical trial.

scientific article published on September 1994

Interleukin-1 alpha-mediated promotion of long-term alloengraftment and short-term neutrophil expansion does not require the presence of either donor or host T cells

scientific article published on 01 September 1996

Interleukin-1 blockade does not prevent acute graft-versus-host disease: results of a randomized, double-blind, placebo-controlled trial of interleukin-1 receptor antagonist in allogeneic bone marrow transplantation

scientific article published on 18 July 2002

Interleukin-1 or tumor necrosis factor-alpha antagonists do not inhibit graft-versus-host disease induced across the major histocompatibility barrier in mice

scientific article published on 01 December 1995

Interleukin-10 administration decreases survival in murine recipients of major histocompatibility complex disparate donor bone marrow grafts

scientific article published on 01 February 1995

Interleukin-10 dose-dependent regulation of CD4+ and CD8+ T cell-mediated graft-versus-host disease

scientific article published on 01 November 1998

Interleukin-2 gene transfer into murine neuroblastoma decreases tumorigenicity and enhances systemic immunity causing regression of preestablished retroperitoneal tumors

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Interleukin-2 secretion by transduced and unselected BDL-2 lymphoma results in increased survival in mice with previously established disseminated disease

scientific article published on 01 April 1996

Interleukin-22 protects intestinal stem cells from immune-mediated tissue damage and regulates sensitivity to graft versus host disease

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Interleukin-27 Enforces Regulatory T Cell Functions to Prevent Graft-versus-Host Disease

scientific article published on 12 February 2020

Intestinal Helminth Colonization Regulates Lethal Graft Versus Host Disease and Preserves Graft Versus Tumor in Bone Marrow Transplanted Mice ⬇️

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Intestinal Immune Conditioning with Helminths Employs Host T Helper 2 (Th2) Pathway to Induce Mixed Chimerism and Regulate Graft-Versus-Host Disease ⬇️

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Intestinal helminths regulate lethal acute graft-versus-host disease and preserve the graft-versus-tumor effect in mice.

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Intravital imaging of donor allogeneic effector and regulatory T cells with host dendritic cells during GVHD.

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Invariant natural killer T cells ameliorate murine chronic GVHD by expanding donor regulatory T cells

scientific article published on 17 April 2017

Invasive Fusarium infections in bone marrow transplant recipients

scientific article published on October 1984

Irradiation of singly and doubly transduced murine neuroblastoma cells expressing B7-1 and producing interferon-gamma reduces their capacity to induce systemic immunity

scientific article published on 01 March 1996

Isoform-specific targeting of ROCK proteins in immune cells

scientific article published on 2 June 2016

KGF and androgen blockade work in concert to protect against conditioning regimen‐induced thymic epithelial damage and enhance T‐cell reconstitution following murine BMT ⬇️

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KGF pretreatment decreases B7 and granzyme B expression and hastens repair in lungs of mice after allogeneic BMT

scientific article published on 01 May 2000

Keratinocyte growth factor (KGF) enhances postnatal T-cell development via enhancements in proliferation and function of thymic epithelial cells

scientific article published on 9 January 2007

Keratinocyte growth factor administered before conditioning ameliorates graft-versus-host disease after allogeneic bone marrow transplantation in mice

scientific article published on 01 November 1998

Keratinocyte growth factor and androgen blockade work in concert to protect against conditioning regimen-induced thymic epithelial damage and enhance T-cell reconstitution after murine bone marrow transplantation

scientific article published on 11 March 2008

Keratinocyte growth factor augments immune reconstitution after autologous hematopoietic progenitor cell transplantation in rhesus macaques

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Keratinocyte growth factor facilitates alloengraftment and ameliorates graft-versus-host disease in mice by a mechanism independent of repair of conditioning-induced tissue injury

scientific article published on 01 December 2000

Keratinocyte growth factor preserves normal thymopoiesis and thymic microenvironment during experimental graft-versus-host disease

scientific article published on 01 July 2002

Keratinocytes from induced pluripotent stem cells in junctional epidermolysis bullosa

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Kinetics of Chimerism and Unit Predominance After Double Umbilical Cord Blood Transplantation ⬇️

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Kupffer cell engraftment across the major histocompatibility barrier in mice: bone marrow origin, class II antigen expression, and antigen-presenting capacity.

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L-Selectin(hi) but not the L-selectin(lo) CD4+25+ T-regulatory cells are potent inhibitors of GVHD and BM graft rejection

scientific article published on 3 August 2004

Lack of GVHD across classical, single minor histocompatibiliTy (miH) locus barriers in mice

scientific article published on 01 February 1996

Late Acute Graft-versus-Host Disease after Allogeneic Hematopoietic Stem Cell Transplantation

scientific article published on 29 December 2015

Late administration of murine CTLA-4 blockade prolongs CD8-mediated anti-tumor effects following stimulatory cancer immunotherapy

scientific article published on 30 September 2015

Lethal murine graft-versus-host disease induced by donor gamma/delta expressing T cells with specificity for host nonclassical major histocompatibility complex class Ib antigens

scientific article published on 01 January 1996

Leukocyte migration and graft-versus-host disease

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Licensing delineates helper and effector NK cell subsets during viral infection

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Ligation of 4-1BB (CDw137) regulates graft-versus-host disease, graft-versus-leukemia, and graft rejection in allogeneic bone marrow transplant recipients

scientific article published on 01 March 2001

Ligation of CD137 receptor prevents and reverses established anergy of CD8+ cytolytic T lymphocytes in vivo

scientific article published on 11 September 2003

Ligation of OX40 (CD134) regulates graft-versus-host disease (GVHD) and graft rejection in allogeneic bone marrow transplant recipients

scientific article published on 09 January 2003

Limited role of MHC class I chain-related gene A (MICA) typing in assessing graft-versus-host disease risk after fully human leukocyte antigen-matched unrelated donor transplantation

scientific article published on 01 November 2009

Lineage relationships of human interleukin-22–producing CD56+ RORγt+ innate lymphoid cells and conventional natural killer cells ⬇️

scientific article published on January 17, 2013

Lipid Composition of Whole Brain and Cerebellum in Hurler Syndrome (MPS IH) Mice

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Long-term follow-up of a phase I/II randomized, placebo-controlled trial of palifermin to prevent graft-versus-host disease (GVHD) after related donor allogeneic hematopoietic cell transplantation (HCT).

scientific article published on September 2008

Long-term outcome of Hurler syndrome following bone marrow transplantation

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Loss of Programmed Death Ligand-1 Expression on Donor T Cells Lessens Acute Graft-Versus-Host Disease Lethality ⬇️

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Loss of T Follicular Helper Cells in the Peripheral Blood of Patients with Chronic Graft-versus-Host Disease

scientific article published on 12 January 2016

Low EGF in myeloablative allotransplantation: association with severe acute GvHD in BMT CTN 0402

scientific article published on 05 June 2017

Low day +100 serum epidermal growth factor levels are associated with acute GvHD after allogeneic hematopoietic cell transplantation

scientific article published on 21 November 2016

Low dose subcutaneous interleukin-2 after autologous transplantation generates sustained in vivo natural killer cell activity

scientific article published on April 1, 1997

Low-Dose Interleukin-2 Therapy Restores Regulatory T Cell Homeostasis in Patients with Chronic Graft-Versus-Host Disease ⬇️

scientific article published on April 3, 2013

Low-dose IL-2 selectively activates subsets of CD4+ Tregs and NK cells

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Lower leukemia relapse in pediatric patients with pulmonary cytolytic thrombi following allogeneic transplant

scientific article published on 14 June 2010

Lung parenchyma-derived IL-6 promotes IL-17A-dependent acute lung injury after allogeneic stem cell transplantation

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Lymphodepletion followed by donor lymphocyte infusion (DLI) causes significantly more acute graft-versus-host disease than DLI alone

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MHC Class II Antigen Presentation by the Intestinal Epithelium Initiates Graft-versus-Host Disease and Is Influenced by the Microbiota

scientific article published on 18 September 2019

Maintenance of CD4 T cell fitness through regulation of Foxo1

scientific article published on 09 July 2018

Major breakthroughs in hematopoietic stem cell transplantation and future challenges in clinical implementation ⬇️

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Manipulating and visualizing T-cell alloresponses

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Massive ex vivo expansion of human natural regulatory T cells (T(regs)) with minimal loss of in vivo functional activity

scientific article published on May 2011

Mechanisms Responsible for and Strategies To Overcome Bone Marrow (BM) Rejection in Allosensitized Recipients. ⬇️

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Mechanisms of donor-specific transfusion tolerance: preemptive induction of clonal T-cell exhaustion via indirect presentation

scientific article published on 15 May 2003

Memory T cells in GVHD and GVL.

scientific article published on January 2008

Mesenchymal stromal cells from donors varying widely in age are of equal cellular fitness after in vitro expansion under hypoxic conditions

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Mesenchymal stromal cells shape the MDS microenvironment by inducing suppressive monocytes that dampen NK cell function

scientific article published on 12 March 2020

Metabolic reprogramming augments potency of human pSTAT3-inhibited iTregs to suppress alloreactivity

scientific article published on 07 April 2020

Metabolic reprogramming of donor T cells enhances graft-versus-leukemia effects in mice and humans

scientific article published on 01 October 2020

Mgta-456, a Cell Therapy Utilizing Expansion of CD34+ Hematopoietic Stem Cells (HSC), Improves HLA Matching for Adult Recipients, Promotes Faster Hematopoietic Recovery and Enables Uniform Engraftment with Less Acute Graft-Vs-Host Disease (GVHD) ⬇️

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MiR-155 Impacts T Cell Migration in Acute Graft-Versus-Host Disease (aGVHD) ⬇️

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MiR-17-92 Is Required for the Pathogenicity of T and B Cells in Chronic Gvhd ⬇️

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MicroRNA-155 Modulates Acute Graft-versus-Host Disease by Impacting T Cell Expansion, Migration, and Effector Function

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MicroRNA-17-92 is required for T-cell and B-cell pathogenicity in chronic graft-versus-host disease in mice

scientific article published on 12 March 2018

MicroRNAs Control the Maintenance of Thymic Epithelia and Their Competence for T Lineage Commitment and Thymocyte Selection ⬇️

scientific article published on September 12, 2012

Microbial translocation is a cause of systemic immune activation in chronic HIV infection

scientific article published on 19 November 2006

Minicircle DNA is Superior to Plasmid DNA in Eliciting Antigen-specific CD8+ T-cell Responses ⬇️

scientific article published on May 21, 2013

Minicircle DNA-based gene therapy coupled with immune modulation permits long-term expression of α-L-iduronidase in mice with mucopolysaccharidosis type I

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Minimal PD-1 expression in mouse and human NK cells under diverse conditions

scientific article published on 05 March 2020

Minimum Information about T Regulatory Cells: A Step toward Reproducibility and Standardization

scientific article published in January 2017

Mitochondrial Integrity Regulated by Lipid Metabolism Is a Cell-Intrinsic Checkpoint for Treg Suppressive Function

scientific article published on 26 December 2019

Modification of T cell responses by stem cell mobilization requires direct signaling of the T cell by G-CSF and IL-10

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Modulation of Immune Checkpoints and Graft-versus-Leukemia in Allogeneic Transplants by Antagonizing Vasoactive Intestinal Peptide Signaling

scientific article published on 26 September 2016

Molecular modification of a recombinant anti-CD3epsilon-directed immunotoxin by inducing terminal cysteine bridging enhances anti-GVHD efficacy and reduces organ toxicity in a lethal murine model

scientific article published on 01 August 2000

Monocyte Subpopulation Recovery and Outcomes Following Hematopoietic Cell Transplantation ⬇️

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Monocyte Subpopulation Recovery as Predictors of Hematopoietic Cell Transplantation Outcomes

scientific article published on 06 January 2019

Monomeric annexin A2 is an oxygen-regulated toll-like receptor 2 ligand and adjuvant

scientific article published on 16 February 2016

Mouse Ly49G2+ NK cells dominate early responses during both immune reconstitution and activation independently of MHC

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Mucocutaneous Engraftment and Type VII Collagen (C7) Replacement after Allogeneic Hematopoietic Cell Transplantation (HCT) in Patients with Recessive Dystrophic Epidermolysis Bullosa (RDEB) ⬇️

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Multicenter Open-Label Phase 2 Study of Ibrutinib in Chronic Graft Versus Host Disease (cGVHD) after Failure of Corticosteroids ⬇️

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Multipotent adult progenitor cells can suppress graft-versus-host disease via prostaglandin E2 synthesis and only if localized to sites of allopriming

scientific article published on 20 May 2009

Murine CAR19 Tregs suppress acute graft-versus-host disease and maintain graft-versus-tumor responses

scientific article published in 2022

Murine chronic graft-versus-host disease proteome profiling discovers CCL15 as a novel biomarker in patients

scientific article published on 18 January 2018

Murine gamma/delta-expressing T cells affect alloengraftment via the recognition of nonclassical major histocompatibility complex class Ib antigens

scientific article published on 01 May 1996

Murine recipients of fully mismatched donor marrow are protected from lethal graft-versus-host disease by the in vivo administration of rapamycin but develop an autoimmune-like syndrome

scientific article published on 01 November 1993

Myeloablative hematopoietic cell transplantation for acute lymphoblastic leukemia: analysis of graft sources and long-term outcome.

scientific article published on 06 July 2009

Myeloperoxidase deficiency enhances inflammation after allogeneic marrow transplantation

scientific article published on 12 March 2004

NCI First International Workshop on The Biology, Prevention, and Treatment of Relapse After Allogeneic Hematopoietic Stem Cell Transplantation: Report from the Committee on the Biology Underlying Recurrence of Malignant Disease following Allogeneic

scientific article published on 10 February 2010

NK Cells Lacking CD38 Are Resistant to Oxidative Stress-Induced Death ⬇️

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NK inhibitory-receptor blockade for purging of leukemia: effects on hematopoietic reconstitution

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NK-cell purging of leukemia: superior antitumor effects of NK cells H2 allogeneic to the tumor and augmentation with inhibitory receptor blockade

scientific article published on 31 July 2003

Natural history of pulmonary complications in children after bone marrow transplantation

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Natural killer–cell differentiation by myeloid progenitors ⬇️

scientific article published on December 20, 2010

Negative Impact of KIR-Ligand Mismatch on Transplant-Related Mortality (TRM) in Umbilical Cord Blood Transplant (UCBT) Recipients. ⬇️

scholarly article

Negative effect of CTLA-4 on induction of T-cell immunity in vivo to B7-1+, but not B7-2+, murine myelogenous leukemia

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Negative effect of KIR alloreactivity in recipients of umbilical cord blood transplant depends on transplantation conditioning intensity

scientific article published on 27 March 2009

Neutrophils provide cellular communication between ileum and mesenteric lymph nodes at graft-versus-host disease onset

scientific article published on 20 February 2018

New strategies for preventing graft-versus-host disease

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Nfatc2 and Tob1 have non-overlapping function in T cell negative regulation and tumorigenesis

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Nonhuman primate transplant models finally evolve: detailed immunogenetic analysis creates new models and strengthens the old.

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Nonmitogenic anti-CD3F(ab')2 fragments inhibit lethal murine graft-versus-host disease induced across the major histocompatibility barrier

scientific article published on 01 January 1993

Notch signaling at later stages of NK cell development enhances KIR expression and functional maturation

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Notch signaling mediated by Delta-like ligands 1 and 4 controls the pathogenesis of chronic GVHD in mice

scientific article published on 04 September 2018

Obesity induces gut microbiota alterations and augments acute graft-versus-host disease after allogeneic stem cell transplantation

scientific article published on 01 November 2020

Oncogenic JAK2V617F causes PD-L1 expression, mediating immune escape in myeloproliferative neoplasms.

scientific article published in February 2018

Oncogenic KrasG12D causes myeloproliferation via NLRP3 inflammasome activation

scientific article published on 03 April 2020

Opposing Effects of CD70 Costimulation during Acute and Chronic Lymphocytic Choriomeningitis Virus Infection of Mice ⬇️

scientific article published on April 20, 2011

Opposing roles of CD28:B7 and CTLA-4:B7 pathways in regulating in vivo alloresponses in murine recipients of MHC disparate T cells

scientific article published on 01 June 1999

Opposing roles of interferon-gamma on CD4+ T cell-mediated graft-versus-host disease: effects of conditioning

scientific article published on 01 January 2000

Optimal Xenogeneic Adoptive Transfer of Human NK Cells: Fresh NK Cells and IL-15 Administration Are Superior to Frozen NK Cells and IL-2 ⬇️

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Optimization of cGMP purification and expansion of umbilical cord blood-derived T-regulatory cells in support of first-in-human clinical trials

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Organ-Specific Protection By Bortezomib On The Treatment Of Cutaneous Chronic and Acute GvHD ⬇️

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Organ-Specific Protection from CD8+ T Cell-Mediated Acute Skin GVHD by Bortezomib Administration Correlates with Decreased IL-6. ⬇️

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Osteosarcoma Derived from Cultured Mesenchymal Stem Cells. ⬇️

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Out-of-Sequence Signal 3 Paralyzes Primary CD4(+) T-Cell-Dependent Immunity

scientific article published on 28 July 2015

Outcome of CNS and pulmonary enteroviral infections after hematopoietic cell transplantation

scientific article published on 01 July 2005

Outcome of dialysis for acute renal failure in pediatric bone marrow transplant patients

scientific article published on May 1994

Outcome of second bone marrow transplantation following a uniform conditioning regimen as therapy for malignant relapse

scientific article published on 01 January 1996

Outcomes and Predictors of Response in Steroid-Refractory Acute Graft-versus-Host Disease

scientific article published on 17 July 2019

Outcomes of Chronic Graft-Versus-Host Disease (cGVHD) Following Matched Sibling Donor (MSD) Versus Umbilical Cord Blood Transplant (UCBT) ⬇️

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Outgrowth of CD4low/negCD25+ T cells with suppressor function in CD4+CD25+ T cell cultures upon polyclonal stimulation ex vivo

scientific article published on December 2008

Overcoming T cell-mediated rejection of bone marrow allografts by T-regulatory cells: synergism with veto cells and rapamycin

scientific article published on 01 June 2006

Oxygen is a master regulator of the immunogenicity of primary human glioma cells

scientific article published on 9 September 2011

PD-1 Blockade Reverses Obesity-Mediated T Cell Priming Impairment

scientific article published on 29 October 2020

PD-1 blockade for relapsed lymphoma post-allogeneic hematopoietic cell transplant: high response rate but frequent GVHD.

scientific article published on 3 May 2017

PD-1 restraint of regulatory T cell suppressive activity is critical for immune tolerance

scientific article published on 01 January 2021

PD-L1 blockade effectively restores strong graft-versus-leukemia effects without graft-versus-host disease after delayed adoptive transfer of T-cell receptor gene-engineered allogeneic CD8+ T cells ⬇️

scientific article published on November 9, 2010

PD-L1 signaling selectively regulates T cell lymphatic transendothelial migration

scientific article published on 21 April 2022

PDL1 is required for peripheral transplantation tolerance and protection from chronic allograft rejection

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PKC-θ function at the immunological synapse: prospects for therapeutic targeting

scientific article published on 04 July 2011

PKCtheta is required for alloreactivity and GVHD but not for immune responses toward leukemia and infection in mice

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Palifermin for oral mucositis after intensive therapy for hematologic cancers

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Palifermin reduces patient-reported mouth and throat soreness and improves patient functioning in the hematopoietic stem-cell transplantation setting

scientific article published on 3 January 2006

Paradoxical effects of obesity on T cell function during tumor progression and PD-1 checkpoint blockade.

scientific article published on 12 November 2018

Pathogenesis of acute graft-versus-host disease: from intestinal microbiota alterations to donor T cell activation

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Pathology of the liver in mucopolysaccharidosis: light and electron microscopic assessment before and after bone marrow transplantation

scientific article published on 01 September 1992

Pathophysiology of Chronic Graft-versus-Host Disease and Therapeutic Targets

scientific article published in December 2017

Patient-specific naturally gene-reverted induced pluripotent stem cells in recessive dystrophic epidermolysis bullosa

scientific article published on 06 December 2013

Pediatric acute GVHD: clinical phenotype and response to upfront steroids

scientific article published on 02 September 2019

Peri-alloHCT IL-33 administration expands recipient T-regulatory cells that protect mice against acute GVHD.

scientific article published on 24 May 2016

Peritransplant glucocorticoids redistribute donor T cells to the bone marrow and prevent relapse after haploidentical SCT

scientific article published on 22 November 2021

Peritransplant palifermin use and lymphocyte recovery after T-cell replete, matched related allogeneic hematopoietic cell transplantation ⬇️

scientific article published on October 1, 2011

Persistent STAT5 activation reprograms the epigenetic landscape in CD4+ T cells to drive polyfunctionality and antitumor immunity

scientific article published on 01 October 2020

Peyer patches are not required for acute graft-versus-host disease after myeloablative conditioning and murine allogeneic bone marrow transplantation

scientific article published on 13 September 2005

Pharmacologic Blockade of Notch/Delta-like Ligand 4 Signaling Protects from Gastrointestinal Acute Graft-Versus-Host Disease in Non-Human Primates ⬇️

scholarly article

Pharmacologic inhibition of PKCα and PKCθ prevents GVHD while preserving GVL activity in mice ⬇️

scientific article published on October 3, 2013

Phase 1/2 randomized, placebo-control trial of palifermin to prevent graft-versus-host disease (GVHD) after allogeneic hematopoietic stem cell transplantation (HSCT).

scientific article published on 11 July 2006

Phase I Study of Alemtuzumab for Therapy of Steroid-Refractory Chronic Graft-versus-Host Disease ⬇️

scientific article published on February 14, 2013

Phase I/II Trial of StemRegenin-1 Expanded Umbilical Cord Blood Hematopoietic Stem Cells Supports Testing as a Stand-Alone Graft

scientific article published on 05 December 2015

Phenyl N-Tert-Butylnitrone (PBN) Protects Syngeneic Marrow Transplant Recipients from the Lethal Cytokine Syndrome Occurring after Agonistic CD40 Antibody Administration. ⬇️

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Phosphonooxymethyl Prodrug of Triptolide: Synthesis, Physicochemical Characterization, and Efficacy in Human Colon Adenocarcinoma and Ovarian Cancer Xenografts

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Photochemical treatment of donor lymphocytes inhibited their ability to facilitate donor engraftment or increase donor chimerism after nonmyeloablative conditioning or establishment of mixed chimerism

scientific article published in January 2002

Physiologic Control of IDO Competence in Splenic Dendritic Cells ⬇️

scientific article published on August 3, 2011

Pig embryonic pancreatic tissue as a source for transplantation in diabetes: transient treatment with anti-LFA1, anti-CD48, and FTY720 enables long-term graft maintenance in mice with only mild ongoing immunosuppression

scientific article published on 28 April 2009

Pirfenidone ameliorates murine chronic GVHD through inhibition of macrophage infiltration and TGF-β production

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Plasma pharmacokinetics of high-dose oral busulfan in children and adults undergoing bone marrow transplantation

scientific article published in January 2003

Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenase

scientific article published in September 2007

Polyamines and eIF5A Hypusination Modulate Mitochondrial Respiration and Macrophage Activation

scientific article published on 23 May 2019

Polyfunctional CD4+ T cells are essential for eradicating advanced B-cell lymphoma after chemotherapy ⬇️

scientific article published on August 2, 2012

Post-BMT lung injury occurs independently of the expression of CCL2 or its receptor, CCR2, on host cells ⬇️

scientific article published on October 3, 2003

Post-transplantation B cell activating factor and B cell recovery before onset of chronic graft-versus-host disease

scientific article published on 23 January 2014

Pre-transplant risk factors affecting outcome in Hurler syndrome

scientific article published on 9 November 2009

Preclinical Testing of Antihuman CD28 Fab' Antibody in a Novel Nonhuman Primate Small Animal Rodent Model of Xenogenic Graft-Versus-Host Disease

scientific article published in December 2016

Preclinical models of acute and chronic graft-versus-host disease: how predictive are they for a successful clinical translation?

scientific article published on 18 March 2016

Predictive factors for chronic graft-versus-host disease after histocompatible sibling donor bone marrow transplantation

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Preformed antibody, not primed T cells, is the initial and major barrier to bone marrow engraftment in allosensitized recipients

scientific article published on 3 October 2006

Preparedness of the CTSA's structural and scientific assets to support the mission of the National Center for Advancing Translational Sciences (NCATS)

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Pretransplant Serum Citrulline Predicts Acute Graft-versus-Host Disease

scientific article published on 07 July 2018

Pretransplant conditioning with busulfan (Myleran) and cyclophosphamide for nonmalignant diseases. Assessment of engraftment following histocompatible allogeneic bone marrow transplantation

scientific article published on 01 June 1985

Pretreatment of murine donor grafts with L-leucyl-L-leucine methyl ester: elimination of graft-versus-host disease without detrimental effects on engraftment

scientific article published in February 1990

Prevention of Acute GvHD During MHC Haploidentical BMT: Evaluating the Efficacy of T-Cell Costimulation Blockade Using a Novel Rhesus Macaque Transplant Model. ⬇️

scholarly article

Prevention of Acute GvHD during Haplo-BMT: Evaluating the Efficacy of T-Cell Costimulation Blockade Using a Novel Rhesus Macaque Transplant Model ⬇️

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Prevention of graft-versus-host disease by adoptive T regulatory therapy is associated with active repression of peripheral blood Toll-like receptor 5 mRNA expression

scientific article published on November 2013

Prevention of murine graft-versus-host disease and bone marrow alloengraftment across the major histocompatibility barrier after donor graft preincubation with anti-LFA1 immunotoxin

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Program death-1 signaling and regulatory T cells collaborate to resist the function of adoptively transferred cytotoxic T lymphocytes in advanced acute myeloid leukemia.

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Programmed death ligand-1 expression on donor T cells drives graft-versus-host disease lethality

scientific article published on 13 June 2016

Programming of Donor T Cells Using Allogeneic Delta-like Ligand 4-Positive Dendritic Cells to Reduce Gvhd but Retain GVL Activity ⬇️

scholarly article

Programming of donor T cells using allogeneic δ-like ligand 4-positive dendritic cells to reduce GVHD in mice.

scientific article published on 03 May 2016

Prolonged subcutaneous administration of 852A, a novel systemic toll‐like receptor 7 agonist, to activate innate immune responses in patients with advanced hematologic malignancies ⬇️

scientific article published on June 20, 2012

Promising Progression Free and Overall Survival Using a Novel (CY/FLU/TBI) Reduced-Intensity Conditioning (RIC) Regimen for Allogeneic Sibling Stem Cell Transplantation (SCT). ⬇️

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Promising progression-free survival for patients low and intermediate grade lymphoid malignancies after nonmyeloablative umbilical cord blood transplantation

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Promotion of murine marrow alloengraftment and hematopoietic recovery across the major histocompatibility barrier by administration of recombinant human interleukin-1 alpha ⬇️

scientific article published on September 15, 1992

Prospective randomized trial between two doses of granulocyte colony-stimulating factor after ifosfamide, carboplatin, and etoposide in children with recurrent or refractory solid tumors: a children's cancer group report

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Protection from thymic epithelial cell injury by keratinocyte growth factor: a new approach to improve thymic and peripheral T-cell reconstitution after bone marrow transplantation

scientific article published on 01 June 2002

Protein Kinase C-Theta Interacts with mTORC2 and Vimentin to Limit Regulatory T-Cell Function ⬇️

scholarly article

Protein kinase C-theta mediates negative feedback on regulatory T cell function

scientific article published on 25 March 2010

Proteomics analysis reveals a Th17-prone cell population in presymptomatic graft-versus-host disease

scientific article published on May 2016

Publisher Correction: Absence of NKG2D ligands defines leukaemia stem cells and mediates their immune evasion

scientific article published on 01 August 2019

Pulmonary Complications Due to Iduronidase Deficiency (Hurler Syndrome) Linked to Active Pro-Inflammatory Status. ⬇️

scholarly article

ROCK1/2 signaling contributes to corticosteroid-refractory acute graft-versus-host disease

scientific article published in 2024

ROCK2 signaling is required to induce a subset of T follicular helper cells through opposing effects on STATs in autoimmune settings

scientific article published on 19 July 2016

Radiotherapy in mice with yttrium-90-labeled anti-Ly1 monoclonal antibody: therapy of established graft-versus-host disease induced across the major histocompatibility barrier

scientific article published on 01 April 1991

Radiotherapy in mice with yttrium-90-labeled anti-Ly1 monoclonal antibody: therapy of the T cell lymphoma EL4

scientific article published on 01 April 1991

Randomized clinical trial of thalidomide, cyclosporine, and prednisone versus cyclosporine and prednisone as initial therapy for chronic graft-versus-host disease

scientific article published in January 2001

Randomized comparison of cyclophosphamide-total body irradiation versus busulfan-cyclophosphamide conditioning in autologous bone marrow transplantation for acute myeloid leukemia

scientific article published on 01 January 1995

Rapamycin inhibits the generation of graft-versus-host disease- and graft-versus-leukemia-causing T cells by interfering with the production of Th1 or Th1 cytotoxic cytokines ⬇️

scientific article published on June 1, 1998

Rapamycin prolongs survival of murine recipients of fully allogeneic donor grafts when administered during the graft-versus-host disease process

scientific article published on 01 June 1993

Rapamycin, a potent inhibitor of T-cell function, prevents graft rejection in murine recipients of allogeneic T-cell-depleted donor marrow

scientific article published on 01 January 1994

Rapid and complete donor chimerism in adult recipients of unrelated donor umbilical cord blood transplantation after reduced-intensity conditioning

scientific article published on 8 May 2003

Re-Opening Schools Safely: The Case for Collaboration, Constructive Disruption of Pre-COVID Expectations, and Creative Solutions

scientific article published on 20 May 2020

Reactivity of murine cytokine fusion toxin, diphtheria toxin390-murine interleukin-3 (DT390-mIL-3), with bone marrow progenitor cells

scientific article

Real-time in vivo imaging of stem cells following transgenesis by transposition

scientific article published in July 2005

Recent advances in graft‐versus‐host disease (GVHD) prevention ⬇️

scientific article published on June 1, 1997

Receptors and counterreceptors involved in NK-B cell interactions

scientific article published on 01 April 2005

Recipient T Cell Exhaustion and Successful Adoptive Transfer of Haploidentical Natural Killer Cells.

scientific article published on 29 November 2017

Recipient single nucleotide polymorphisms in Paneth cell antimicrobial peptide genes and acute graft-versus-host disease: analysis of BMT CTN-0201 and -0901 samples

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Recipient-specific T-cell repertoire reconstitution in the gut following murine hematopoietic cell transplant

scientific article published on 01 September 2020

Recombinant granulocyte/macrophage-colony stimulating factor in human and murine bone marrow transplantation

scientific article published on 01 August 1988

Reduced intensity compared with high dose conditioning for allotransplantation in acute myeloid leukemia and myelodysplastic syndrome: a comparative clinical analysis

scientific article published in October 2007

Reduced-Intensity Conditioning Followed by Related and Unrelated Allografts for Hematologic Malignancies: Expanded Analysis and Long-Term Follow-Up

scientific article published on 01 August 2018

Reduced-intensity conditioning followed by related allografts in hematologic malignancies: long-term outcomes most successful in indolent and aggressive non-Hodgkin lymphomas

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Reduction in murine acute GVHD severity by human gingival tissue-derived mesenchymal stem cells via the CD39 pathways

scholarly article by Xuhao Ni et al published 8 January 2019 in Cell Death and Disease

Regulation of Immune Responses during Acute GvHD Via the IL-33/ST2 Axis ⬇️

scholarly article

Regulation of acute graft-versus-host disease by microRNA-155.

scientific article

Regulation of glutathione redox status in lung and liver by conditioning regimens and keratinocyte growth factor in murine allogeneic bone marrow transplantation ⬇️

scientific article published on October 27, 2001

Regulation of intestinal inflammation by microbiota following allogeneic bone marrow transplantation

scientific article

Regulatory T Cells Condition Lymphatic Endothelia for Enhanced Transendothelial Migration

scientific article published on 01 January 2020

Regulatory T cell expressed MyD88 is critical for prolongation of allograft survival

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Regulatory T cells

scientific article published on 01 February 2005

Regulatory T cells exhibit decreased proliferation but enhanced suppression after pulsing with sirolimus

scientific article

Regulatory T cells in acute myelogenous leukemia: is it time for immunomodulation? ⬇️

scientific article published on August 31, 2011

Regulatory and conventional CD4+ T cells show differential effects correlating with PD-1 and B7-H1 expression after immunotherapy

scientific article published on March 2008

Relapse risk after umbilical cord blood transplantation: enhanced graft-versus-leukemia effect in recipients of 2 units

scientific article published on 25 August 2009

Relationship of Epidermal Growth Factor to Cyclosporine-Assocated Magnesium Wasting and Clinical Outcomes Post-Allogeneic Hematopoietic Cell Transplantation ⬇️

scholarly article

Relationship of plasma pharmacokinetics of high-dose oral busulfan to the outcome of allogeneic bone marrow transplantation in children with thalassemia

scientific article published on 01 December 1997

Removal of Donor CD4+ T Cells Markedly Promotes Graft-Versus-Tumor (GVT) Effects and Inhibits GVHD-Dependent Toxicity Associated with Prolonged Bortezomib Administration after Allogeneic BMT. ⬇️

scholarly article

Renal dysfunction accounts for the dose limiting toxicity of DT390anti- CD3sFv, a potential new recombinant anti-GVHD immunotoxin ⬇️

scientific article published on September 1, 1997

Repeated PD-1/PD-L1 monoclonal antibody administration induces fatal xenogeneic hypersensitivity reactions in a murine model of breast cancer

scientific article published on 12 August 2015

Reply

Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation

scientific article published on 14 August 2011

Reprint of: B cells in chronic graft-versus-host disease

scientific article

Reprogrammed foxp3(+) regulatory T cells provide essential help to support cross-presentation and CD8(+) T cell priming in naive mice

scientific article published on 9 December 2010

Repurposing a novel anti-cancer RXR agonist to attenuate acute GVHD and maintain graft-versus-leukemia responses

scientific article published on 24 September 2020

Requirements for the promotion of allogeneic engraftment by anti-CD154 (anti-CD40L) monoclonal antibody under nonmyeloablative conditions

Rescue of exhausted CD8 T cells by PD-1-targeted therapies is CD28-dependent.

scientific article

Response of 443 patients to steroids as primary therapy for acute graft-versus-host disease: comparison of grading systems

scientific article published in January 2002

Restoration of CCL21 Accelerates Lymph Node (LN) and Spleen Regeneration Post-Transplant and Improves Anti-Pathogen and Anti-Tumor Effector Responses ⬇️

scholarly article

Restriction fragment length polymorphisms as markers of engraftment in allogeneic marrow transplantation

scientific article published on 01 December 1985

Resurrecting the recalcitrant T-cell ⬇️

scientific article published on October 20, 2011

Retinoic acid and rapamycin differentially affect and synergistically promote the ex vivo expansion of natural human T regulatory cells

scientific article (publication date: 6 January 2011)

Retroviral immunotoxin gene therapy of acute myelogenous leukemia in mice using cytotoxic T cells transduced with an interleukin 4/diphtheria toxin gene.

scientific article

Retroviral-mediated transfer of the iduronate-2-sulfatase gene into lymphocytes for treatment of mild Hunter syndrome (mucopolysaccharidosis type II)

scientific article published on 01 March 1996

Retroviral-mediated transfer of the murine interleukin-3 gene engineered for intracellular retention results in a myeloproliferative syndrome but is associated with circulating interleukin-3 levels.

scientific article published in August 1993

Ribosome-Targeting Antibiotics Impair T Cell Effector Function and Ameliorate Autoimmunity by Blocking Mitochondrial Protein Synthesis

scientific article published on 17 November 2020

Risk Factors for Acute and Chronic Graft-versus-Host Disease after Allogeneic Hematopoietic Cell Transplantation with Umbilical Cord Blood and Matched Sibling Donors

scientific article published on 10 September 2015

Risk Factors for Acute and Chronic Gvhd after Allogeneic Hematopoietic Cell Transplantation (allo-HCT): Relative Risks with Umbilical Cord Blood (UCB) and Matched Related Donors (MRD) ⬇️

scholarly article

Risk factors for acute graft-versus-host disease in histocompatible donor bone marrow transplantation

scientific article published on 01 June 1991

Rituximab prophylaxis prevents corticosteroid-requiring chronic GVHD after allogeneic peripheral blood stem cell transplantation: results of a phase 2 trial

scientific article published on 16 July 2013

Robert Truitt tribute

scientific article published on 15 October 2009

Role of PD-1/PD-L1 in Acute and Chronic Graft Versus Host Disease ⬇️

scholarly article

Role of Recipient CD8+ T Cell Exhaustion in the Rejection of Adoptively Transferred Haploidentical NK Cells ⬇️

scholarly article

Role of interleukin-12 in acute graft-versus-host disease(1)

scientific article published on 01 February 2001

Role of myeloid-derived suppressor cells in allogeneic hematopoietic cell transplantation

scientific article published on February 2017

Role of transgene regulation in ex vivo lentiviral correction of artemis deficiency

scientific article published on 13 April 2015

Roles of CD28, CTLA4, and Inducible Costimulator in Acute Graft-versus-Host Disease in Mice ⬇️

scientific article published on March 27, 2011

Rorc restrains the potency of ST2+ regulatory T cells in ameliorating intestinal graft-versus-host disease

scientific article published on 07 March 2019

ST2 blockade reduces sST2-producing T cells while maintaining protective mST2-expressing T cells during graft-versus-host disease.

scientific article

STAT3 signaling in CD4+ T cells is critical for the pathogenesis of chronic sclerodermatous graft-versus-host disease in a murine model

scientific article

STAT6 and Furin Are Successive Triggers for the Production of TGF-β by T Cells

scientific article published on 28 September 2018

STING differentially regulates experimental GVHD mediated by CD8 versus CD4 T cell subsets

scientific article published on 01 July 2020

Salmonella-mediated therapy targeting indoleamine 2, 3-dioxygenase 1 (IDO) activates innate immunity and mitigates colorectal cancer growth

scientific article published on 01 March 2019

Sarcoma derived from cultured mesenchymal stem cells

scientific article published on 12 October 2006

Scaffold protein Disc large homolog 1 is required for T-cell receptor-induced activation of regulatory T-cell function

scientific article published on 17 January 2012

Second infusion of bone marrow for treatment of graft failure after allogeneic bone marrow transplantation

scientific article published on 01 July 1994

Selective oral ROCK2 inhibitor down-regulates IL-21 and IL-17 secretion in human T cells via STAT3-dependent mechanism

scientific article

Sensitive and adaptable pharmacological control of CAR T cells through extracellular receptor dimerization

scientific article published on 30 April 2019

Separation of graft-versus-host disease from graft-versus-leukemia responses by targeting CC-chemokine receptor 7 on donor T cells

scientific article

Serum miR-29a Is Upregulated in Acute Graft-versus-Host Disease and Activates Dendritic Cells through TLR Binding

scientific article published on 3 February 2017

Short-course total-lymphoid irradiation combined with total-body irradiation to facilitate engraftment of T cell-depleted marrow across a major histocompatibility barrier in mice

scientific article published on 01 August 1988

Short-term ex vivo activation of splenocytes with anti-CD3 plus IL-2 and infusion post-BMT into mice results in in vivo expansion of effector cells with potent anti-lymphoma activity

scientific article published on 01 October 1994

Short-term inhibition of p53 combined with keratinocyte growth factor improves thymic epithelial cell recovery and enhances T-cell reconstitution after murine bone marrow transplantation

scientific article

Shotgun sequencing of the faecal microbiome to predict response to steroids in patients with lower gastrointestinal acute graft-versus-host disease: An exploratory analysis

scientific article published on 22 November 2020

Signatures of CD8+ T cell dysfunction in AML patients and their reversibility with response to chemotherapy

scientific article published on 02 November 2018

Signatures of immune dysfunction predict outcomes and define checkpoint blockade-unresponsive microenvironments in acute myeloid leukemia

scientific article published in 2022

Simultaneous absence of surfactant proteins A and D increases lung inflammation and injury after allogeneic HSCT in mice

scientific article

Sirolimus and GvHD Control: the Rhesus Macaque GvHD Model Reveals That Sirolimus Preferentially Inhibits T Cell Proliferation While Permitting Breakthrough T cell Activation After MHC-Mismatched Hematopoietic Stem Cell Transplantation ⬇️

scholarly article

Sirolimus and Mycophenolate Mofetil as Calcineurin Inhibitor-Free Graft-versus-Host Disease Prophylaxis for Reduced-Intensity Conditioning Umbilical Cord Blood Transplantation

scientific article published on 9 August 2016

Skeletal muscle contractile function and neuromuscular performance in Zmpste24 -/- mice, a murine model of human progeria

scientific article published on 29 June 2011

Sleeping Beauty transposon-mediated engineering of human primary T cells for therapy of CD19+ lymphoid malignancies

scientific article

Sleeping Beauty-Mediated Transposition in Stem Cells

scholarly article

Sleeping Beauty-mediated correction of Fanconi anemia type C.

scientific article

Small-molecule BCL6 inhibitor effectively treats mice with non-sclerodermatous chronic graft-versus-host disease

article

Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells.

scientific article published on 12 February 2018

Stable gene transfer and expression in human primary T cells by the Sleeping Beauty transposon system

scientific article published on 27 September 2005

Stem Cell Source Dependent Differences in Reconstituting Peripheral T Follicular Helper Cells Following Hematopoietic Cell Transplantation, Their Association with Chronic Gvhd and Role in Response to Influenza Vaccination ⬇️

scholarly article

Stem cell gene therapy for fanconi anemia: report from the 1st international Fanconi anemia gene therapy working group meeting.

scientific article

Stress responses, M2 macrophages, and a distinct microbial signature in fatal intestinal acute graft-versus-host disease

scientific article published on 08 August 2019

Striking Clinical, Molecular and Immunological Outcomes in Non-Human Primate Hematopoietic Stem Cell Transplantation Using a Novel OX40L Blockade Agent, KY1005, Combined with Rapamycin ⬇️

scholarly article

Stromal cell-derived factor-1 and hematopoietic cell homing in an adult zebrafish model of hematopoietic cell transplantation

scientific article published on 26 May 2011

Su1897 – Intestinal Immune Conditioning with Helminths Employ Host T Helper 2 (TH2) Pathway to Induce Mixed Chimerism and Regulate Colitis Associated with Graft-Versus-Host Disease

scholarly article

Successful Remission Rates and Survival after Lymphodepleting Chemotherapy and Donor Lymphocyte Infusion for Relapsed Hematologic Malignancies Postallogeneic Hematopoietic Cell Transplantation ⬇️

scientific article published on December 10, 2011

Successful adoptive transfer and in vivo expansion of human haploidentical NK cells in patients with cancer

scientific article (publication date: 15 April 2005)

Successful allogeneic cryopreserved marrow transplantation

scientific article published on 01 February 1989

Successful donor cell engraftment in a recipient of bone marrow from a cadaveric donor

scientific article published in June 1986

Superior efficacy of tumor cell vaccines grown in physiologic oxygen

scientific article

Superiority of rapamycin over tacrolimus in preserving nonhuman primate Treg half-life and phenotype after adoptive transfer

scientific article

Suppression of NK Cell-Mediated Bone Marrow Cell Rejection by CD4+CD25+ Regulatory T Cells: Linkage of Adaptive to Innate Responses. ⬇️

scholarly article

Suppression of natural killer cell-mediated bone marrow cell rejection by CD4+CD25+ regulatory T cells

scholarly article

Suppressor function of umbilical cord blood-derived CD4+CD25+ T-regulatory cells exposed to graft-versus-host disease drugs

scientific article published on 01 July 2006

Surfactant protein A decreases lung injury and mortality after murine marrow transplantation

scientific article

Surfactant protein A is a required mediator of keratinocyte growth factor after experimental marrow transplantation

scientific article published on 9 May 2003

Sustained thymopoiesis and improvement in functional immunity induced by exogenous KGF administration in murine models of aging

scientific article published on 30 November 2006

Synergistic anti-tumor responses after administration of agonistic antibodies to CD40 and IL-2: coordination of dendritic and CD8+ cell responses

scientific article published on 01 March 2003

Synthetic unmethylated cytosine-phosphate-guanosine oligodeoxynucleotides are potent stimulators of antileukemia responses in naive and bone marrow transplant recipients

scientific article published in August 2001

Synthetic zinc finger nuclease design and rapid assembly

scientific article published on 10 August 2011

Systemic delivery of Salmonella typhimurium transformed with IDO shRNA enhances intratumoral vector colonization and suppresses tumor growth

scientific article

Systems analysis uncovers inflammatory Th/Tc17-driven modules during acute GVHD in monkey and human T cells

scientific article published on 06 October 2016

T Stem Cell Memory Dynamics during Acute Graft-Versus-Host Disease ⬇️

scholarly article

T cell depletion for graft-versus-host-disease prophylaxis. A perspective on engraftment in mice and humans

scientific article published on May 1989

T cell depletion with anti-CD5 immunotoxin in histocompatible bone marrow transplantation. The correlation between residual CD5 negative T cells and subsequent graft-versus-host disease ⬇️

scientific article published on 01 September 1990

T cell progenitor therapy-facilitated thymopoiesis depends upon thymic input and continued thymic microenvironment interaction

scientific article

T-Cell Transcriptome Analysis Reveals the Mechanisms Controlling Synergy Between Costimulation Blockade and mTOR Inhibition during Graft Versus Host Disease Prevention ⬇️

scholarly article

T-cell expression of AhR inhibits the maintenance of pTreg cells in the gastrointestinal tract in acute GVHD.

scientific article published on 26 May 2017

T-lymphocyte production of macrophage inflammatory protein-1alpha is critical to the recruitment of CD8(+) T cells to the liver, lung, and spleen during graft-versus-host disease.

scientific article

TALEN-based gene correction for epidermolysis bullosa.

scientific article published on 2 April 2013

TCR affinity and specificity requirements for human regulatory T-cell function ⬇️

scientific article published on February 7, 2012

TLR agonists regulate alloresponses and uncover a critical role for donor APCs in allogeneic bone marrow rejection

scientific article published on 09 July 2008

TRAF6 directs FOXP3 localization and facilitates regulatory T-cell function through K63-linked ubiquitination

scientific article published on 18 March 2019

Targeted Rho-associated kinase 2 inhibition suppresses murine and human chronic GVHD through a Stat3-dependent mechanism.

scientific article published on 16 March 2016

Targeting BCL6 and Germinal Centers (GCs) in Chronic Graft-Versus-Host Disease (cGVHD) Using Direct and Epigenomic Therapies ⬇️

scholarly article

Targeting PI3Kδ function for amelioration of murine chronic graft-versus-host disease

scientific article published on 19 March 2019

Targeting PKCtheta Inhibits Alloreactivity and Graft-Versus-Host Disease While Preserving Graft-Versus-Leukemia and Anti-Infection Activities. ⬇️

scholarly article

Targeting Syk-activated B cells in murine and human chronic graft-versus-host disease

scientific article published on 7 April 2015

Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity

scientific article

Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity

scientific article published on 30 May 2011

Targeting myeloid leukemia with a DT(390)-mIL-3 fusion immunotoxin: ex vivo and in vivo studies in mice

scientific article published on 01 September 1999

Targeting of inducible costimulator (ICOS) expressed on alloreactive T cells down-regulates graft-versus-host disease (GVHD) and facilitates engraftment of allogeneic bone marrow (BM).

scientific article published on 23 December 2004

Targeting of the CNS in MPS-IH Using a Nonviral Transferrin-α-l-iduronidase Fusion Gene Product

Targeting of the CNS in MPS-IH using a nonviral transferrin-alpha-L-iduronidase fusion gene product

scientific article published on 03 June 2008

Th17/Th22 Cells Mediate Breakthrough Graft-Versus-Host-Disease ⬇️

scholarly article

The Balance Between Donor T Cell Anergy and Suppression Versus Lethal Graft-Versus-Host Disease Is Determined by Host Conditioning

scientific article published on 01 November 2002

The Biology of Chronic Graft-versus-Host Disease: A Task Force Report from the National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease

scientific article

The IL-33/ST2 axis augments effector T-cell responses during acute GVHD.

scientific article published on 26 March 2015

The Innate Immune Sensor Sting Promotes Donor CD8+ T Cell Activation and Recipient APC Death Early after Preclinical Allogeneic Hematopoietic Stem Cell Transplantation ⬇️

scholarly article

The Knife's Edge of Tolerance: Inducing Stable Multilineage Mixed Chimerism but With a Significant Risk of CMV Reactivation and Disease in Rhesus Macaques

scientific article published on 8 August 2016

The PTEN pathway in Tregs functions as a critical driver of the immunosuppressive tumor microenvironment and tolerance to apoptotic cells.

scientific article published on 4 November 2015

The PTEN pathway in Tregs is a critical driver of the suppressive tumor microenvironment

scientific article published on 6 November 2015

The Past, Present, and Future of NK Cells in Hematopoietic Cell Transplantation and Adoptive Transfer

scientific article published on 03 June 2015

The Programmed Death-1 Ligand 1:B7-1 Pathway Restrains Diabetogenic Effector T Cells In Vivo ⬇️

scientific article published on June 22, 2011

The Unexpected and Differential Effect of Cyclosporin A on CD56Bright and CD56Dim NK Cell Expansion, Phenotype, Function and Development from Progenitor Cells. ⬇️

scholarly article

The adjuvant effects of Mycobacterium tuberculosis heat shock protein 70 result from the rapid and prolonged activation of antigen-specific CD8+ T cells in vivo

scientific article published on November 2002

The critical early proinflammatory events associated with idiopathic pneumonia syndrome in irradiated murine allogeneic recipients are due to donor T cell infusion and potentiated by cyclophosphamide

scientific article published on September 1997

The effect of T subset depletion on the incidence of lethal graft-versus-host disease in a murine major-histocompatibility-complex-mismatched transplantation system

scientific article published on 01 March 1987

The host immune response is essential for the beneficial effect of adult stem cells after myocardial ischemia

scientific article published in April 2007

The indoleamine 2,3-dioxygenase pathway is essential for human plasmacytoid dendritic cell-induced adaptive T regulatory cell generation

scientific article

The infusion of ex vivo activated and expanded CD4(+)CD25(+) immune regulatory cells inhibits graft-versus-host disease lethality

scientific article published on 01 May 2002

The lineage stability and suppressive program of regulatory T cells require protein O-GlcNAcylation

scientific article published in Nature Communications

The lymph node stromal laminin alpha 5 shapes alloimmunity

scientific article published on 04 February 2020

The novel costimulatory programmed death ligand 1/B7.1 pathway is functional in inhibiting alloimmune responses in vivo

scientific article

The proteasome inhibitor PS-341 sensitizes neoplastic cells to TRAIL-mediated apoptosis by reducing levels of c-FLIP.

scientific article published on 13 March 2003

The purinergic receptor P2RX7 directs metabolic fitness of long-lived memory CD8 T cells

scientific article published in Nature

The puzzling world of murine T regulatory cells.

scientific article

The role of B7 costimulation by murine acute myeloid leukemia in the generation and function of a CD8+ T-cell line with potent in vivo graft-versus-leukemia properties.

scientific article published on May 1997

The role of T cell subsets in regulating the in vivo efficacy of CTLA4-Ig in preventing graft-versus-host disease in recipients of fully MHC or multiple minor histocompatibility-disparate donor inocula

scientific article published on 01 December 1994

The role of host T cell subsets in bone marrow rejection directed to isolated major histocompatibility complex class I versus class II differences of bm1 and bm12 mutant mice

scientific article published on 01 January 1994

The tissue expression of cytokines in human acute cutaneous graft-versus-host disease ⬇️

scientific article published on August 27, 1995

The unexpected effect of cyclosporin A on CD56+CD16- and CD56+CD16+ natural killer cell subpopulations

scientific article

The vimentin intermediate filament network restrains regulatory T cell suppression of graft-versus-host disease

Therapeutic activity of multiple common γ-chain cytokine inhibition in acute and chronic GVHD

scientific article

Therapeutic benefit of bortezomib on acute graft-versus-host disease is tissue specific and is associated with interleukin-6 levels

scientific article

Therapeutic regulatory T-cell adoptive transfer ameliorates established murine chronic GVHD in a CXCR5-dependent manner

scientific article published on 6 July 2016

Therapy for ongoing graft-versus-host disease induced across the major or minor histocompatibility barrier in mice with anti-CD3F(ab')2-ricin toxin A chain immunotoxin

scientific article published on 01 December 1995

Third Party Type 2 Innate Lymphoid Cells Treat and Prevent GI Tract Acute GvHD ⬇️

scholarly article

Thrombopoietic cytokines in relation to platelet recovery after bone marrow transplantation

scientific article

Thrombopoietin cooperates with FLT3-ligand in the generation of plasmacytoid dendritic cell precursors from human hematopoietic progenitors

scientific article

Thymic Epithelial Cell Support of Thymopoiesis Does Not Require

scientific article published on 29 October 2018

Thymic Shielding (TS) in Recipients of Total Body Irradiation (TBI) and Alternative Donor Hematopoietic Stem Cell Transplant (AD-HSCT): Reduced Risk of Opportunistic Infection in Patients with Fanconi Anemia (FA). ⬇️

scholarly article

Thymic T-cell development in allogeneic stem cell transplantation ⬇️

scientific article published on March 22, 2011

Thymic stromal lymphopoietin is not necessary or sufficient to mediate the thymopoietic effects of keratinocyte growth factor

scientific article published on January 2008

Tim-3 is an inducible human natural killer cell receptor that enhances interferon gamma production in response to galectin-9 ⬇️

scientific article published on February 8, 2012

Tim-3, a Novel Immune Receptor, Is Constitutively Expressed on Human Natural Killer Cells and Functions as An Activating Coreceptor ⬇️

scholarly article

Tissue mast cell counts may be associated with decreased severity of gastrointestinal acute GVHD and nonrelapse mortality

scientific article published on 01 May 2020

Tolerance induction by third-party "off-the-shelf" CD4+CD25+ Treg cells

scientific article published on January 2006

Tolerance induction of alloreactive T cells via ex vivo blockade of the CD40:CD40L costimulatory pathway results in the generation of a potent immune regulatory cell

scientific article published on 01 June 2002

Toll-like receptor 9 signaling by CpG-B oligodeoxynucleotides induces an apoptotic pathway in human chronic lymphocytic leukemia B cells

scientific article

Toxicity and efficacy of anti-T-cell ricin toxin A chain immunotoxins in a murine model of established graft-versus-host disease induced across the major histocompatibility barrier

scientific article published on 01 January 1991

Trans-presentation of donor-derived interleukin 15 is necessary for the rapid onset of acute graft-versus-host disease but not for graft-versus-tumor activity

scientific article published on 6 June 2006

Transcriptome analysis of GVHD reveals aurora kinase A as a targetable pathway for disease prevention

scientific article published on November 2015

Transfection of the mouse ICAM-1 gene into murine neuroblastoma enhances susceptibility to lysis, reduces in vivo tumorigenicity and decreases ICAM-2-dependent killing

scientific article

Transgene expression and silencing in a tick cell line: A model system for functional tick genomics

scientific article

Transgenesis of Multipotent Adult Progenitor Cells (MAPC) with Sleeping Beauty Transposons to Determine MAPC Homing and Persistence in Real-Time In Vivo. ⬇️

scholarly article

Transgenic mice expressing either bovine growth hormone (bGH) or human GH releasing hormone (hGRH) have increased splenic progenitor cell colony formation and DNA synthesis in vitro and in vivo

scientific article published on 01 December 1995

Transient blockade of the inducible costimulator pathway generates long-term tolerance to factor VIII after nonviral gene transfer into hemophilia A mice

scientific article published on 23 June 2008

Transient regulatory T-cell (Treg) depletion with IL-2 diphtheria toxin fusion protein enhances clearance of acute myeloid leukemia by haploidentical natural killer (NK) cells.

scientific article published on 7 November 2013

Transplantation of 2 partially HLA-matched umbilical cord blood units to enhance engraftment in adults with hematologic malignancy

scientific article published on 05 October 2004

Transplantation of ex-vivo culture-expanded parental haploidentical mesenchymal stem cells to promote engraftment in pediatric recipients of unrelated donor umbilical cord blood: results of a phase I-II clinical trial

scientific article published on 27 October 2008

Transplantation of unrelated donor umbilical cord blood in 102 patients with malignant and nonmalignant diseases: influence of CD34 cell dose and HLA disparity on treatment-related mortality and survival

scientific article

Treatment of Corticosteroid-Refractory Graft-Versus-Host Disease with Ruxolitinib in 95 Patients ⬇️

scholarly article

Treatment of chronic graft-versus-host disease with bortezomib

scientific article

Treatment of moderate and severe acute GVHD after allogeneic bone marrow transplantation

scientific article published on 01 August 1994

Treatment of moderate/severe acute graft-versus-host disease after allogeneic bone marrow transplantation: an analysis of clinical risk features and outcome

scientific article published in February 1990

Treg engage lymphotoxin beta receptor for afferent lymphatic transendothelial migration

scientific article

Trispecific Killer Engagers (TriKEs) that contain IL-15 to make NK cells antigen specific and to sustain their persistence and expansion ⬇️

scholarly article

Tumor growth control with IDO-silencing Salmonella--reply

scientific article published on 5 July 2013

Tumor regression by anti-CD40 and interleukin-2: role of CD40 in hematopoietic cells and organ-specific effects

scientific article published on August 2004

Tumor-induced mechanical hyperalgesia involves CGRP receptors and altered innervation and vascularization of DsRed2 fluorescent hindpaw tumors

scientific article

Type 2 innate lymphoid cells treat and prevent acute gastrointestinal graft-versus-host disease

scientific article published on 4 April 2017

Umbilical Cord Blood T Cells Express the Natural Cytotoxicity Receptors, NKp30, NKp44 and NKp46 after IL-15 Stimulation, but Only NKp30 Is Functional. ⬇️

scholarly article

Umbilical cord blood T cells express multiple natural cytotoxicity receptors after IL-15 stimulation, but only NKp30 is functional

scientific article published on October 2008

Umbilical cord blood regulatory T-cell expansion and functional effects of tumor necrosis factor receptor family members OX40 and 4-1BB expressed on artificial antigen-presenting cells

scientific article published on 21 July 2008

Umbilical cord blood transplantation after nonmyeloablative conditioning: impact on transplantation outcomes in 110 adults with hematologic disease

scientific article

Umbilical cord blood-derived T regulatory cells to prevent GVHD: kinetics, toxicity profile, and clinical effect

scientific article published on 12 November 2015

Understanding Luminal Microorganisms and Their Potential Effectiveness in Treating Intestinal Inflammation

scientific article published on 8 October 2015

Understanding chronic GVHD from different angles

scientific article published on January 2012

Unrelated donor bone marrow transplantation for children and adolescents with aplastic anaemia or myelodysplasia

scientific article published on 01 March 1997

Unrelated donor bone marrow transplantation for children with acute leukemia

scientific article published on 01 February 1997

Unrelated donor bone marrow transplantation for correction of lethal congenital immunodeficiencies

scientific article published on 01 July 1992

Unrelated donor bone marrow transplantation for hematological malignancies-current status

scientific article published on 01 October 1996

Unrelated donor bone marrow transplantation therapy for chronic myelogenous leukemia

scientific article published on 01 September 1987

Unrelated donor bone marrow transplantation: influence of HLA A and B incompatibility on outcome

scientific article published on 01 August 1995

VIP-Receptor Antagonist Enhanced Antileukemic Activity In Mice ⬇️

scholarly article

VISTA Re-programs Macrophage Biology Through the Combined Regulation of Tolerance and Anti-inflammatory Pathways

scientific article published on 15 October 2020

VISTA is a checkpoint regulator for naïve T cell quiescence and peripheral tolerance

scientific article

Vaccination with dendritic cells loaded with allogeneic brain tumor cells for recurrent malignant brain tumors induces a CD4(+)IL17(+) response

scientific article

Validation of Minnesota Acute GVHD Risk Score and Identification of New Factors Associated with Initial Response to Steroids: Not All GVHD Is Created Equal ⬇️

scholarly article

Validation of Minnesota acute graft-versus-host disease Risk Score

scientific article published on 31 January 2020

Virus-specific memory T cells populate tumors and can be repurposed for tumor immunotherapy

scientific article published in Nature Communications

Vstm3 is a member of the CD28 family and an important modulator of T-cell function

scientific journal article

What is the Optimal Design-Build-Test Cycle for Clinically Relevant Synthetic CAR T Cell Therapies?

scientific article published on 01 September 2020

Zebrafish stromal cells have endothelial properties and support hematopoietic cells

scientific article published on 12 September 2011

Zinc fingers hit off target ⬇️

scientific article published on October 11, 2011

iPSC-derived NK cells maintain high cytotoxicity and enhance in vivo tumor control in concert with T cells and anti-PD-1 therapy

scientific article published on 01 November 2020

mAbs to Bacillus anthracis capsular antigen for immunoprotection in anthrax and detection of antigenemia

scholarly article

miR-142-3p regulates autophagy by targeting ATG16L1 in thymic-derived regulatory T cell (tTreg).

scientific article published on 19 February 2018

miR-146b antagomir-treated human Tregs acquire increased GVHD inhibitory potency

scientific article published on 2 August 2016

miR-221 and miR-155 regulate human dendritic cell development, apoptosis, and IL-12 production through targeting of p27kip1, KPC1, and SOCS-1 ⬇️

scientific article published on February 25, 2011

p27kip1 functions as an anergy factor inhibiting interleukin 2 transcription and clonal expansion of alloreactive human and mouse helper T lymphocytes

scientific article published on 01 March 2000

sdf1 Expression reveals a source of perivascular-derived mesenchymal stem cells in zebrafish

scientific article

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