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List of works by Adam Sharp

A phase 1b trial of the combination of an all-oral regimen of capecitabine and erlotinib in advanced non-small cell lung cancer in Caucasian patients.

scientific article published on 26 December 2015

Activation of MAPK Signaling by CXCR7 Leads to Enzalutamide Resistance in Prostate Cancer

scientific article published on 05 April 2019

Alternative splicing in prostate cancer

scientific article published on 01 November 2018

Analytical Validation and Clinical Qualification of a New Immunohistochemical Assay for Androgen Receptor Splice Variant-7 Protein Expression in Metastatic Castration-resistant Prostate Cancer.

scientific article

Androgen receptor splice variant-7 expression emerges with castration resistance in prostate cancer

scientific article published on 26 November 2018

Androgen receptor-modulatory microRNAs provide insight into therapy resistance and therapeutic targets in advanced prostate cancer

scientific article published on 01 May 2019

BAG-1 in carcinogenesis.

scientific article published on 22 March 2004

BRD4 Promotes DNA Repair and Mediates the Formation of TMPRSS2-ERG Gene Rearrangements in Prostate Cancer.

scientific article published in January 2018

CDCP1 overexpression drives prostate cancer progression and can be targeted in vivo

scientific article published on 06 April 2020

Circulating Cell-Free DNA to Guide Prostate Cancer Treatment with PARP Inhibition.

scientific article published on 27 April 2017

Clinical Utility of Circulating Tumour Cell Androgen Receptor Splice Variant-7 Status in Metastatic Castration-resistant Prostate Cancer

scientific article published on 27 April 2019

Correction: Activation of MAPK Signaling by CXCR7 Leads to Enzalutamide Resistance in Prostate Cancer

scientific article published on 01 May 2020

Development of Bag-1L as a therapeutic target in androgen receptor-dependent prostate cancer

scientific article published on 10 August 2017

Development of molecularly targeted agents and immunotherapies in small cell lung cancer.

scientific article published on 6 April 2016

Dissecting Prognostic From Predictive Utility: Circulating AR-V7 Biomarker Testing for Advanced Prostate Cancer

scientific article published on 02 July 2019

Docetaxel Treatment in PTEN- and ERG-aberrant Metastatic Prostate Cancers

scientific article published on 01 May 2018

Dose-reduced trastuzumab emtansine: active and safe in acute hepatic dysfunction

scientific article

Focused molecular analysis of small cell lung cancer: feasibility in routine clinical practice

scientific article published on 18 November 2015

Genomic Analysis of Three Metastatic Prostate Cancer Patients with Exceptional Responses to Carboplatin Indicating Different Types of DNA Repair Deficiency

article

HER3 Is an Actionable Target in Advanced Prostate Cancer

scientific article published on 09 November 2021

IL-23 secreted by myeloid cells drives castration-resistant prostate cancer

scientific article published in Nature

Immunogenomic analyses associate immunological alterations with mismatch repair defects in prostate cancer

scientific article published on 04 September 2018

Investigating Genomic Aberrations of the Androgen Receptor: Moving Closer to More Precise Prostate Cancer Care?

scientific article published on 21 February 2017

JMJD6 Is a Druggable Oxygenase That Regulates AR-V7 Expression in Prostate Cancer

scientific article published on 01 February 2021

Managing Metastatic Castration-Resistant Prostate Cancer in the Pre-chemotherapy Setting: A Changing Approach in the Era of New Targeted Agents.

scientific article published on 12 February 2016

Neutrophil to Lymphocyte Ratio in Castration-Resistant Prostate Cancer Patients Treated With Daily Oral Corticosteroids.

scientific article published on 10 May 2017

Novel Junction-specific and Quantifiable In Situ Detection of AR-V7 and its Clinical Correlates in Metastatic Castration-resistant Prostate Cancer

scientific article published on 30 August 2017

Nuclear Circulating Tumor Cell Androgen Receptor Variant 7 in Castration-Resistant Prostate Cancer: The Devil Is in the Detail

scientific article published on 01 September 2018

Prostate cancer research: The next generation; report from the 2019 Coffey-Holden Prostate Cancer Academy Meeting

scientific article published on 11 December 2019

RB1 Heterogeneity in Advanced Metastatic Castration Resistant Prostate Cancer

scientific article published on 26 September 2018

SPOP-Mutated/CHD1-Deleted Lethal Prostate Cancer and Abiraterone Sensitivity

scientific article published on 01 August 2018

Short peptides derived from the BAG-1 C-terminus inhibit the interaction between BAG-1 and HSC70 and decrease breast cancer cell growth

scientific article

Single-Cell Analyses of Prostate Cancer Liquid Biopsies Acquired by Apheresis

scientific article published on 09 August 2018

Targeting Androgen Receptor Aberrations in Castration-Resistant Prostate Cancer

scientific article published on 21 June 2016

Targeting Bromodomain and Extra-Terminal (BET) Family Proteins in Castration-Resistant Prostate Cancer (CRPC).

scientific article published on 19 March 2018

Targeting the p300/CBP Axis in Lethal Prostate Cancer

scientific article published on 11 January 2021

The landscape of RNA polymerase II associated chromatin interactions in prostate cancer

scientific article published on 28 April 2020

The nuclear BAG-1 isoform, BAG-1L, enhances oestrogen-dependent transcription.

scientific article published in August 2003

The retinoblastoma protein interacts with Bag-1 in human colonic adenoma and carcinoma derived cell lines

scientific article published in September 2003

Thioflavin S (NSC71948) interferes with Bcl-2-associated athanogene (BAG-1)-mediated protein-protein interactions.

scientific article published on 18 August 2009