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List of works by Christopher P Mack

Blood pressure-associated polymorphism controls ARHGAP42 expression via serum response factor DNA binding

scientific article published on 23 January 2017

Conditional deletion of focal adhesion kinase leads to defects in ventricular septation and outflow tract alignment

scientific article

DNA methylation of a GC repressor element in the smooth muscle myosin heavy chain promoter facilitates binding of the Notch-associated transcription factor, RBPJ/CSL1.

scientific article published on 16 October 2014

Diaphanous 1 and 2 regulate smooth muscle cell differentiation by activating the myocardin-related transcription factors.

scientific article

Enhancement of mDia2 activity by Rho-kinase-dependent phosphorylation of the diaphanous autoregulatory domain

scientific article published on October 2011

FAK regulates cardiomyocyte survival following ischemia/reperfusion

scientific article

FRNK expression promotes smooth muscle cell maturation during vascular development and after vascular injury

scientific article

Focal Adhesion Kinase-mediated Phosphorylation of Beclin1 Protein Suppresses Cardiomyocyte Autophagy and Initiates Hypertrophic Growth ⬇️

scientific article published on 19 December 2016

Focal adhesion kinase antagonizes doxorubicin cardiotoxicity via p21(Cip1.).

scientific article

Focal adhesion kinase is essential for cardiac looping and multichamber heart formation

scientific article published on August 2010

Focal adhesion kinase regulates smooth muscle cell recruitment to the developing vasculature

scientific article published on 14 July 2011

Formin homology domain-containing protein 1 regulates smooth muscle cell phenotype

scientific article published on 24 November 2010

GRAF1 deficiency blunts sarcolemmal injury repair and exacerbates cardiac and skeletal muscle pathology in dystrophin-deficient mice

scientific article published on 21 August 2015

GRAF1 promotes ferlin-dependent myoblast fusion

scientific article

Germline deletion of FAK-related non-kinase delays post-natal cardiomyocyte mitotic arrest

scientific article published on 25 April 2012

Inhibition of Diaphanous Formin Signaling In Vivo Impairs Cardiovascular Development and Alters Smooth Muscle Cell Phenotype

scientific article published on 17 September 2015

Myocyte-restricted focal adhesion kinase deletion attenuates pressure overload-induced hypertrophy

scientific article

Nuclear RhoA signaling regulates MRTF-dependent SMC-specific transcription

scientific article

PKA-dependent phosphorylation of serum response factor inhibits smooth muscle-specific gene expression

scientific article published on 24 September 2009

Regulation of myocardin factor protein stability by the LIM-only protein FHL2

scientific article published on 27 June 2008

Skeletal muscle differentiation and fusion are regulated by the BAR-containing Rho-GTPase-activating protein (Rho-GAP), GRAF1

scientific article

Smooth muscle cell-specific transcription is regulated by nuclear localization of the myocardin-related transcription factors

scientific article published on 22 September 2006

Sphingosine 1-phosphate receptor 2 signals through leukemia-associated RhoGEF (LARG), to promote smooth muscle cell differentiation

scientific article published on 11 August 2010

Sphingosine 1-phosphate stimulates smooth muscle cell differentiation and proliferation by activating separate serum response factor co-factors

scientific article published on 3 August 2004

Targeted focal adhesion kinase activation in cardiomyocytes protects the heart from ischemia/reperfusion injury

scientific article published on March 2012

The LIM protein leupaxin is enriched in smooth muscle and functions as an serum response factor cofactor to induce smooth muscle cell gene transcription

scientific article

Transient expression of FRNK reveals stage-specific requirement for focal adhesion kinase activity in cardiac growth

scientific article

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