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List of works by Frederick Epstein

1042 Multi-modality magnetic resonance demonstrates factors critical to functional capacity in peripheral arterial disease

152 Gadolinium-labeled liposomes as a DENSE-compatible, positive MRI contrast agent for serially assessing macrophage activity and regional contractile function in the murine heart after myocardial infarction

article

2091 Manganese enhanced mri demonstrates a predominant role for nNOS, not eNOS, in modulating L-Type calcium channel flux in the heart

article

2093 CMR reveals that cardiac-specific overexpression of the inducible form of nitric oxide synthase induces Left Ventricular Hypertrophy in wild-type mice after AAV-Mediated direct gene transfer

article

239 Differentiating moderate from severe coronary artery stenosis using quantitative myocardial perfusion imaging

3D myocardial tissue tracking with slice followed cine DENSE MRI.

scientific article published on May 2008

A Nonpeptide Angiotensin II Type 2 Receptor Agonist Does Not Attenuate Postmyocardial Infarction Left Ventricular Remodeling in Mice

scientific article published on April 1, 2012

A comparison of methods for determining the partition coefficient of gadolinium in the myocardium using T1 mapping

scientific article published on 2 February 2011

A kinematic model‐based analysis framework for 3D Cine‐DENSE—validation with an axially compressed gel phantom and application in sheep before and after antero‐apical myocardial infarction

scientific article published in 2021

A novel cardiac muscle-derived biomaterial reduces dyskinesia and postinfarct left ventricular remodeling in a mouse model of myocardial infarction

scientific article

ASL demonstrates higher and more homogenous calf muscle perfusion with post-occlusion hyperemia than with exercise

Accelerated and navigator-gated look-locker imaging for cardiac T1 Estimation (ANGIE) with reduced motion artifact

Accelerated and navigator-gated look-locker imaging for cardiac T1 estimation (ANGIE): Development and application to T1 mapping of the right ventricle.

scientific article

Accelerated cine DENSE MRI using compressed sensing and parallel imaging

scientific article published on 16 January 2014

Accelerated dual-contrast first-pass perfusion MRI of the mouse heart: development and application to diet-induced obese mice

scientific article

Accelerated first-pass perfusion CMR using compressed sensing with regional spatiotemporal sparsity.

scientific article published on 30 January 2013

Accelerated two-dimensional cine DENSE cardiovascular magnetic resonance using compressed sensing and parallel imaging

scientific article

Accelerating cine DENSE using a zonal excitation.

scientific article

Activation and aponeurosis morphology affect in vivo muscle tissue strains near the myotendinous junction

scientific article

Adeno-associated virus serotype 9 administered systemically after reperfusion preferentially targets cardiomyocytes in the infarct border zone with pharmacodynamics suitable for the attenuation of left ventricular remodeling

scientific article

Angiotensin II type 2 receptor overexpression preserves left ventricular function after myocardial infarction

scientific article

Arterial spin labeling CMR quantifies increased perfusion in hearts of mice treated with cardioprotective, AAV9-mediated EcSOD gene therapy prior to myocardial infarction

article

Arterial spin labeling MR imaging reproducibly measures peak-exercise calf muscle perfusion: a study in patients with peripheral arterial disease and healthy volunteers

scientific article

Arterial spin labeling MRI to measure peak-exercise calf muscle perfusion reproducibly discriminates peripheral arterial disease from normal.

scientific article

Arterial spin labeling perfusion cardiovascular magnetic resonance of the calf in peripheral arterial disease: cuff occlusion hyperemia vs exercise

scientific article

Assessing strain in arrhythmogenic right ventricular cardiomyopathy using cine DENSE MRI

Assessment of advanced coronary artery disease: advantages of quantitative cardiac magnetic resonance perfusion analysis

scientific article

Assessment of regional systolic and diastolic dysfunction in familial hypertrophic cardiomyopathy using MR tagging

scientific article

Automated Motion Estimation for 2-D Cine DENSE MRI

scientific article published on May 3, 2012

Automated cardiac motion estimation from 3D Cine DENSE MRI

Balanced multipoint displacement encoding for DENSE MRI.

scientific article

Black blood gradient echo cine magnetic resonance imaging of the mouse heart

scientific article

Borderzone contractile dysfunction is transiently attenuated and left ventricular structural remodeling is markedly reduced following reperfused myocardial infarction in inducible nitric oxide synthase knockout mice

scientific article

CARDIAC MAGNETIC RESONANCE AFTER CRT DEMONSTRATES DISCORDANT EFFECTS ON RIGHT AND LEFT VENTRICULAR FUNCTION

scholarly article

CMR DENSE and the Seattle Heart Failure Model Inform Survival and Arrhythmia Risk After CRT

scientific article published on 18 December 2019

Calf muscle perfusion at peak exercise in peripheral arterial disease: measurement by first-pass contrast-enhanced magnetic resonance imaging

scientific article

Cardiac MR detects impaired myocardial perfusion reserve and left-ventricular hypertrophy in C57Bl/6 mice fed a high-fat diet.

scientific article published on 16 January 2014

Cardiac MR detects the progression of impaired myocardial perfusion reserve in a mouse model of obesity-related cardiomyopathy

scientific article

Cardiac mechanical activation mapping in heart failure patients with left bundle branch block using cine DENSE MRI

Cardiac motion recovery via active trajectory field models

scientific article

Cardiac remodeling and dysfunction in childhood obesity: a cardiovascular magnetic resonance study

scientific article

Cardiovascular magnetic resonance detects the progression of impaired myocardial perfusion reserve and increased left-ventricular mass in mice fed a high-fat diet

scientific article

Cardiovascular magnetic resonance phase contrast imaging

scientific article

Changes in atherosclerotic plaque composition assessed by MRI in the superficial femoral artery with two years of lipid lowering therapy.

scientific article published on 2 February 2011

Changes in cell fate determine the regenerative and functional capacity of the developing kidney before and after release of obstruction

scientific article published on 05 December 2018

Characterizing the temporal evolution of altered cardiac mechanics in diet-induced obese mice using cine DENSE CMR.

scientific article

Children with obesity have cardiac remodeling and dysfunction: a cine DENSE magnetic resonance imaging study

Cine DENSE MRI detects delayed mechanical activation of the left ventricular free wall in a canine model of heart failure with left bundle branch block

scientific article published on 16 January 2014

Cine DENSE MRI for circumferential and radial dyssynchrony in patients referred for cardiac resynchronization therapy

article

Cine DENSE MRI of mechanical activation in heart failure patients referred for cardiac resynchronization therapy.

scientific article published on 27 January 2016

Cine DENSE strain imaging of the right ventricle: improved methods and initial experience in heart failure.

scientific article published on 16 January 2014

Circumferential Strain Predicts Major Adverse Cardiovascular Events Following an Acute ST-Segment-Elevation Myocardial Infarction

scientific article published on 20 November 2018

Collagen-Targeted MRI Contrast Agent for Molecular Imaging of Fibrosis

scientific article published on 01 January 2007

Comparison of CMR DENSE strain imaging and 2D speckle tracking echocardiography for cardiac resynchronization therapy (CRT) response.

scientific article published on 27 January 2016

Comparison of SNR efficiencies and strain for cine DENSE using conventional EPI, flyback EPI and spiral k-space trajectories

scientific article

Comparison of heart deformation analysis and cine DENSE in volunteers and heart failure patients.

scientific article

Comparison of methods for determining the partition coefficient of gadolinium in the myocardium using T1mapping

scientific article published on November 29, 2012

Complementary displacement-encoded MRI for contrast-enhanced infarct detection and quantification of myocardial function in mice

scientific article

Comprehensive Cardiovascular magnetic resonance of myocardial mechanics in mice using three-dimensional cine DENSE

scientific article published on December 30, 2011

Comprehensive assessment of myocardial mechanics in mice using 3D cine DENSE.

scientific article published on 2 February 2011

Comprehensive assessment of myocardial strain in post-infarct mice using 3D Cine DENSE

article

Delayed calf muscle phosphocreatine recovery after exercise identifies peripheral arterial disease

scientific article

Delineation of anthracyclines and herceptin induced cardiotoxicity using contrast enhanced CMR.

scientific article published on 16 January 2014

Detection of elevated right ventricular extracellular volume in pulmonary hypertension using Accelerated and Navigator-Gated Look-Locker Imaging for Cardiac T1 Estimation (ANGIE) cardiovascular magnetic resonance

scientific article

Detection of increased coronary microvascular permeability with MRI T1 mapping and gadolinium-labeled albumin.

scientific article published on 27 January 2016

Determinants of exercise calf muscle perfusion in Peripheral Arterial Disease (PAD).

scientific article published on 27 January 2016

Diffferential effects of LDL Lowering on CMR measures of calf muscle perfusion and cellular metabolism in peripheral arterial disease

Diffusion-prepared dark blood delayed enhancement imaging for improved detection of subendocardial infarcts

Displacement Encoding With Stimulated Echoes Enables the Identification of Infarct Transmurality Early Postmyocardial Infarction

scientific article published on 27 July 2020

Displacement-encoded and manganese-enhanced cardiac MRI reveal that nNOS, not eNOS, plays a dominant role in modulating contraction and calcium influx in the mammalian heart

scientific article

Displacement-encoded cardiac MRI using cosine and sine modulation to eliminate (CANSEL) artifact-generating echoes

scientific article

Does a selective non-peptide angiotensin II type 2 receptor agonist reduce post-infarction left ventricular remodeling?

article

Does lipid lowering therapy improve calf muscle perfusion and cellular metabolism in peripheral arterial disease?

Does measurement of exercise/rest calf muscle perfusion reserve with first-pass contrast-enhanced MRI in peripheral arterial disease perform better than exercise-only perfusion ?

scientific article published on 2 February 2011

Effect of variable breath-hold positions during cardiac magnetic resonance on measures of left ventricular mechanics

scientific article published on 16 January 2014

Effects of phase encode order and segment interpolation methods on the quality and accuracy of myocardial tags during assessment of left ventricular contraction

scientific article published on 01 January 2002

Electromechanical and scar characteristics at left ventricular lead implant site in the context of overall dyssynchrony with cine DENSE predict cardiac resynchronization therapy outcomes.

scientific article published on 16 January 2014

Emerging MRI Methods in Translational Cardiovascular Research

scientific article published on March 31, 2011

Evaluation of the microcirculation: advances in cardiac magnetic resonance perfusion imaging

scientific article

Feasibility of asymmetric stretch assessment in the ascending aortic wall with DENSE cardiovascular magnetic resonance

scientific article

First-pass contrast-enhanced imaging versus equilibrium-phase T1 mapping for determining the distribution volume of gadolinium.

scientific article published on 2 February 2011

Free-breathing 2D Cine DENSE with Localized Excitation, Self-navigation and Motion Correction

scientific article published on 27 January 2016

Free-breathing cine DENSE MRI using phase cycling with matchmaking and stimulated-echo image-based navigators

Frequency of Coronary Microvascular Dysfunction and Diffuse Myocardial Fibrosis (Measured by Cardiovascular Magnetic Resonance) in Patients With Heart Failure and Preserved Left Ventricular Ejection Fraction

scientific article published on 22 August 2019

High resolution CMR perfusion imaging demonstrates reduced flow reserve and endo/epi ratio in microvascular coronary disease

High resolution cine displacement encoding with stimulated echoes (DENSE) at 3T with navigator feedback for quantification of cardiac mechanics.

scientific article

High temporal-resolution phase-contrast MRI demonstrates impaired left-ventricular diastolic relaxation in mice fed a high-fat high-sucrose diet.

scientific article

High-resolution T1 mapping with ANGIE detects increased right-ventricular extracellular volume fraction in patients with pulmonary arterial hypertension

scientific article

High-resolution quantitative spiral perfusion for microvascular coronary dysfunction detection

scientific article published on 16 January 2014

High-resolution three-dimensional ANGIE T1 mapping of the whole heart

Identification of the S100 fused-type protein hornerin as a regulator of tumor vascularity

scientific article published on 15 September 2017

Illuminating the Path Forward in Cardiac Regeneration Using Strain Magnetic Resonance Imaging

scientific article published on November 2016

Imaging left-ventricular mechanical activation in heart failure patients using cine DENSE MRI: Validation and implications for cardiac resynchronization therapy

scientific article

Imaging three-dimensional myocardial mechanics using navigator-gated volumetric spiral cine DENSE MRI

scientific article

Imaging two-dimensional displacements and strains in skeletal muscle during joint motion by cine DENSE MR

scientific article

Impact of mechanical activation, scar, and electrical timing on cardiac resynchronization therapy response and clinical outcomes

scientific article

Importance of k‐space trajectory in echo‐planar myocardial tagging at rest and during dobutamine stress

scientific article published on October 1, 2003

Improved arterial spin labeling after myocardial infarction in mice using cardiac and respiratory gated look-locker imaging with fuzzy C-means clustering

scientific article

Increased extracellular volume and altered mechanics are associated with LVH in hypertensive heart disease, not hypertension alone

scientific article

Increased extracellular volume and altered mechanics are associated with left ventricular hypertrophy in hypertensive heart disease, not hypertension alone.

scientific article published on 16 January 2014

Increasing the signal-to-noise ratio in DENSE MRI by combining displacement-encoded echoes

scientific article published in July 2004

Infarct involution and improved function during healing of acute myocardial infarction: the role of microvascular obstruction

scientific article

Initiation of statin therapy halts progression of atherosclerotic plaque burden in peripheral arterial disease

Injectable collagen implant improves survival, cardiac remodeling, and function in the early period after myocarditis in rats

scientific article

Interaction between AT1 and AT2 receptors during postinfarction left ventricular remodeling

scientific article

Interaction between bradykinin subtype 2 and angiotensin II type 2 receptors during post-MI left ventricular remodeling

scientific article

Left ventricular mechanical dysfunction in diet-induced obese mice is exacerbated during inotropic stress: a cine DENSE cardiovascular magnetic resonance study

scientific article

Left ventricular mechanical dysfunction in obesity is exacerbated during inotropic stress cine DENSE CMR in mice

scientific article

Low encoding frequencies accurately quantify cardiac mechanics while minimizing phase wrapping in 2D cine DENSE with through-plane dephasing.

scientific article published on 3 February 2015

Low-density lipoprotein lowering does not improve calf muscle perfusion, energetics, or exercise performance in peripheral arterial disease

scientific article published on August 2011

MR cine DENSE dyssynchrony parameters for the evaluation of heart failure: comparison with myocardial tissue tagging

scientific article

MR cine DENSE imaging demonstrates more effective identification of dyssynchrony in heart failure with circumferential and longitudinal strain versus radial strain

MR in mouse models of cardiac disease

scientific article

MR tagging early after myocardial infarction in mice demonstrates contractile dysfunction in adjacent and remote regions

scientific article

MR-based calf muscle perfusion index correlates with treadmill exercise test parameters in patients with peripheral arterial disease.

scientific article published on 30 January 2013

MRI analysis to map interstitial flow in the brain tumor microenvironment

scientific article published on 26 June 2018

MRI assessment of coronary microvascular endothelial nitric oxide synthase function using myocardial T1 mapping

scientific article published on 7 August 2017

MRI of left ventricular function

scientific article

Machine learning for multidimensional response and survival after cardiac resynchronization therapy using features from cardiac magnetic resonance

scientific article published in 2022

Magnetic Resonance Imaging of Myocardial Strain After Acute ST-Segment-Elevation Myocardial Infarction: A Systematic Review

scientific article

Magnetic resonance imaging identifies the fibrous cap in atherosclerotic abdominal aortic aneurysm

scientific article

Manganese-Enhanced Magnetic Resonance Imaging Detects Declining Pancreatic β-Cell Mass in a Cyclophosphamide-Accelerated Mouse Model of Type 1 Diabetes

scientific article published on August 29, 2012

Mapping right ventricular myocardial mechanics using 3D cine DENSE cardiovascular magnetic resonance

scientific article published on January 11, 2012

Mast Cell Inhibition Attenuates Myocardial Damage, Adverse Remodeling, and Dysfunction During Fulminant Myocarditis in the Rat

scientific article published on November 19, 2012

Measurement of myocardial mechanics in mice before and after infarction using multislice displacement-encoded MRI with 3D motion encoding

scientific article

Metabolic Changes in Spontaneously Hypertensive Rat Hearts Precede Cardiac Dysfunction and Left Ventricular Hypertrophy

Metformin Improves Cardiac Metabolism and Function, and Prevents Left Ventricular Hypertrophy in Spontaneously Hypertensive Rats

scientific article published on 04 April 2020

Molecular Imaging of Healing After Myocardial Infarction

scientific article published on February 1, 2011

Monocyte and/or macrophage infiltration of heart after myocardial infarction: MR imaging by using T1-shortening liposomes

scientific article

Motion guided segmentation of the right ventricle for 3D cine DENSE MRI

Motion-compensated compressed sensing for dynamic contrast-enhanced MRI using regional spatiotemporal sparsity and region tracking: block low-rank sparsity with motion-guidance (BLOSM).

scientific article

Motion-corrected compressed-sensing enables robust spiral first-pass perfusion imaging with whole heart coverage.

scientific article published on 16 January 2014

Motion-guided segmentation for cine DENSE MRI

scientific article

Multi-parameter in vivo cardiac magnetic resonance imaging demonstrates normal perfusion reserve despite severely attenuated beta-adrenergic functional response in neuronal nitric oxide synthase knockout mice

scientific article

Multifactorial determinants of functional capacity in peripheral arterial disease: uncoupling of calf muscle perfusion and metabolism

scientific article

Multimodality cardiovascular molecular imaging, part I.

scientific article

Multislice first-pass cardiac perfusion MRI: validation in a model of myocardial infarction

scientific article

Myocardial 3D strain calculation by combining cine displacement encoding with stimulated echoes (DENSE) and cine strain encoding (SENC) imaging

scientific article

Myocardial first-pass perfusion cardiovascular magnetic resonance: history, theory, and current state of the art.

scientific article

Myocardial perfusion using arterial spin labeling CMR: promise and challenges

scientific article

Myocardial perfusion: near-automated evaluation from contrast-enhanced MR images obtained at rest and during vasodilator stress

scientific article

Myocardial tissue tracking with two-dimensional cine displacement-encoded MR imaging: development and initial evaluation

scientific article

Myocardial trajectory estimation for 2D cine DENSE MRI using thin plate splines

Navigator-gated 3D cine DENSE: development and initial evaluation

Nitric oxide mediates benefits of angiotensin II type 2 receptor overexpression during post-infarct remodeling

scientific article

Nitroxide-enhanced MRI of cardiovascular oxidative stress

scientific article published on 09 July 2020

Non-Cartesian slice-GRAPPA and slice-SPIRiT reconstruction methods for multiband spiral cardiac MRI

scientific article published on 30 September 2019

Non-invasive assessment of experimental autoimmune myocarditis in rats using a 3 T clinical MRI scanner

scientific article published on May 3, 2013

Noninvasive assessment of pancreatic beta-cell function in vivo with manganese-enhanced magnetic resonance imaging

scientific article

Obesity reduces left ventricular strains, torsion and synchrony in mouse models: a cine DENSE MRI study

Obesity reduces left ventricular strains, torsion, and synchrony in mouse models: a cine displacement encoding with stimulated echoes (DENSE) cardiovascular magnetic resonance study

scientific article

Patient-specific variability in breath-hold positions during cardiac magnetic resonance imaging has a negligible effect on measures of cardiac mechanics

scientific article published on 3 February 2015

Percutaneous intervention in peripheral artery disease improves calf muscle phosphocreatine recovery kinetics: a pilot study

scientific article

Pharmacologic immunomodulation via adenosine 2a receptor stimulation improves LV remodeling and systolic strain in regions adjacent to the infarct as assessed by cardiac MRI.

scientific article

Phosphocreatine recovery time constant (PCr) at peak exercise as a potential endpoint for clinical trials in PAD.

scientific article

Post-occlusion hyperemia ASL differentiates peripheral artery disease from controls.

scientific article published on 16 January 2014

Postinfarction myocardial scarring in mice: molecular MR imaging with use of a collagen-targeting contrast agent.

scientific article

Predictors of segmental myocardial functional recovery in patients after an acute ST-Elevation myocardial infarction

scientific article published on 14 January 2019

Principle component analysis of myocardial strain to quantify left ventricular dyssynchrony.

scientific article published on 30 January 2013

Prinicipal component analysis of myocardial strains to optimize cardiac resynchronization therapy patient selection

scientific article published on 16 January 2014

Prospectively accelerated first-pass myocardial perfusion imaging in patients using motion-compensated compressed sensing exploiting regional low-rank sparsity.

scientific article published on 3 February 2015

Quantification and MRI validation of regional contractile dysfunction in mice post myocardial infarction using high resolution ultrasound

scientific article

Quantification of left ventricular volumes, mass, and ejection fraction using cine displacement encoding with stimulated echoes (DENSE) MRI

scientific article

Quantification of right ventricular function from short-axis displacement-encoded images.

scientific article published on 16 January 2014

Quantifying myocardial fibrosis in hypertensive left ventricular hypertrophy using T1 mapping

Quantifying right ventricular motion and strain using 3D cine DENSE MRI.

scientific article published on 2 February 2011

Quantitative cardiovascular magnetic resonance perfusion imaging identifies reduced flow reserve in microvascular coronary artery disease.

scientific article

Quantitative first-pass MRI measures increased myocardial perfusion after vasodilation in mice.

scientific article published in February 2012

Quantitative first-pass perfusion MRI of the mouse heart

article

Quantitative pancreatic β cell MRI using manganese-enhanced Look-Locker imaging and two-site water exchange analysis

scientific article

Reduced field of view single-shot spiral perfusion imaging

scientific article

Reduced field-of-view stack-of-spirals enables high spatiotemporal resolution 3D perfusion imaging.

scientific article

Regional diffuse fibrosis and strain characteristics differ between children with hypertrophic and dilated cardiomyopathy.

scientific article published on 3 February 2015

Repeatability and variability of myocardial perfusion imaging techniques in mice: Comparison of arterial spin labeling and first-pass contrast-enhanced MRI.

scientific article

Reperfused myocardial infarction in mice: 3D mapping of late gadolinium enhancement and strain

scientific article published in January 2006

Reproducibility and reliability of atherosclerotic plaque volume measurements in peripheral arterial disease with cardiovascular magnetic resonance

scientific article

Reproducibility of cine displacement encoding with stimulated echoes (DENSE) cardiovascular magnetic resonance for measuring left ventricular strains, torsion, and synchrony in mice.

scientific article

Reproducibility of rest and exercise stress contrast-enhanced calf perfusion magnetic resonance imaging in peripheral arterial disease

scientific article

Selective suppression of artifact-generating echoes in cine DENSE using through-plane dephasing

scientific article

Semi-automated left ventricular segmentation based on a guide point model approach for 3D cine DENSE cardiovascular magnetic resonance

scientific article

Simplified post processing of cine DENSE cardiovascular magnetic resonance for quantification of cardiac mechanics

scientific article

Singular Value Decomposition Applied to Cardiac Strain from MR Imaging for Selection of Optimal Cardiac Resynchronization Therapy Candidates

scientific article

Small-animal molecular imaging methods

scientific article

Spatial and spectral heterogeneity of time-varying shear stress profiles in the carotid bifurcation by phase-contrast MRI.

scientific article

Stunned, infarcted, and normal myocardium in dogs: simultaneous differentiation by using gadolinium-enhanced cine MR imaging with magnetization transfer contrast

scientific article

T2-weighted MRI pulse sequences for imaging post-infarct edema in mice: comparison of spin echo and T2 preparation approaches

article

The angiotensin II type 2 receptor and improved adjacent region function post-MI.

scientific article

The effect of ezetimibe on peripheral arterial atherosclerosis depends upon statin use at baseline

scientific article

The effect of respiratory gating strategy on left ventricular cardiac strains with DENSE

Three‐dimensional phase contrast angiography of the mouse aortic arch using spiral MRI

scientific article published on June 7, 2011

Tracking brain motion during the cardiac cycle using spiral cine-DENSE MRI

scientific article

Tracking myocardial motion from cine DENSE images using spatiotemporal phase unwrapping and temporal fitting

scientific article published in January 2007

Two-dimensional estimates of left ventricular strains are significantly affected by through-plane motion.

scientific article published on 16 January 2014

T₂ -weighted MRI of post-infarct myocardial edema in mice

scientific article

Validation of in vivo 2D Displacements from Spiral Cine DENSE at 3T

Validation of in vivo 2D displacements from spiral cine DENSE at 3T.

scientific article

Whole-Heart Spiral Simultaneous Multi-Slice First-Pass Myocardial Perfusion Imaging

scientific article published on 12 October 2018

Whole-heart T2-weighted (T2w) sequence for imaging post-infarct edematous area at risk (AR) in mice

article

ktrans as a quantitative indicator of calf muscle perfusion at peak exercise.

scientific article published on 16 January 2014