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List of works by Angela F Dulhunty

1H, 13C and 15N assignments for the II-III loop region of the skeletal dyhydropyridine receptor

scientific article published on 01 May 2005

3D Mapping of the SPRY2 Domain of RyR1 by Antibody Labeling and Single-Particle cryo-EM

3D Mapping of the SPRY2 domain of ryanodine receptor 1 by single-particle cryo-EM.

scientific article

A dihydropyridine receptor alpha1s loop region critical for skeletal muscle contraction is intrinsically unstructured and binds to a SPRY domain of the type 1 ryanodine receptor

scientific article published on 8 August 2008

A freeze-fracture study of extensor digitorum longus and soleus muscle fibers from thyrotoxic rats

scientific article published on 01 February 1986

A freeze-fracture study of normal and dystrophic C57BL mouse muscle.

scientific article published on July 1982

A new cytoplasmic interaction between junctin and ryanodine receptor Ca2+ release channels

scientific article

A recently identified member of the glutathione transferase structural family modifies cardiac RyR2 substate activity, coupled gating and activation by Ca2+ and ATP

scientific article

A refractory period after brief activation of mammalian skeletal muscle fibres ⬇️

scientific article published on October 1, 1979

A skeletal muscle ryanodine receptor interaction domain in triadin

scientific article

A structural requirement for activation of skeletal ryanodine receptors by peptides of the dihydropyridine receptor II-III loop

scientific article

A variably spliced region in the type 1 ryanodine receptor may participate in an inter-domain interaction.

scientific article published on January 2007

Actions of perchlorate ions on rat soleus muscle fibres

scientific article published on 01 March 1992

Activating the ryanodine receptor with dihydropyridine receptor II-III loop segments: size and charge do matter

scientific article published in September 2004

Activation of RyR2 by class I kinase inhibitors

scientific article published on 30 January 2019

Activation of the cardiac ryanodine receptor by sulfhydryl oxidation is modified by Mg2+ and ATP

scientific article published on 01 May 1998

Adverse effects of doxorubicin and its metabolic product on cardiac RyR2 and SERCA2A.

scientific article

Agonists and antagonists of the cardiac ryanodine receptor: potential therapeutic agents?

scientific article published on 16 September 2006

Altered mRNA splicing of the skeletal muscle ryanodine receptor and sarcoplasmic/endoplasmic reticulum Ca2+-ATPase in myotonic dystrophy type 1.

scientific article published on 22 June 2005

Alternative splicing of RyR1 alters the efficacy of skeletal EC coupling.

scientific article published on 07 January 2009

An X-linked channelopathy with cardiomegaly due to a CLIC2 mutation enhancing ryanodine receptor channel activity.

scientific article

An α-helical C-terminal tail segment of the skeletal L-type Ca2+ channel β1a subunit activates ryanodine receptor type 1 via a hydrophobic surface

scientific article published on 07 September 2012

Arg(615)Cys substitution in pig skeletal ryanodine receptors increases activation of single channels by a segment of the skeletal DHPR II-III loop

scientific article

Association of FK506 binding proteins with RyR channels - effect of CLIC2 binding on sub-conductance opening and FKBP binding.

scientific article published on 29 August 2017

Beta-adrenergic potentiation of E-C coupling increases force in rat skeletal muscle

scientific article published on 01 December 1993

C-terminal residues of skeletal muscle calsequestrin are essential for calcium binding and for skeletal ryanodine receptor inhibition

scientific article

CLIC-2 modulates cardiac ryanodine receptor Ca2+ release channels

scientific article

Caffeine sensitivity of native RyR channels from normal and malignant hyperthermic pigs: effects of a DHPR II-III loop peptide

scientific article

Calcium ATPase in the sarcoplasmic reticulum of muscle from normal and malignant hyperthermia susceptible pigs

scientific article published on 01 October 1991

Calsequestrin is an inhibitor of skeletal muscle ryanodine receptor calcium release channels

scientific article

Cardiac ryanodine receptor activation by a high Ca²⁺ store load is reversed in a reducing cytoplasmic redox environment.

scientific article

Cardiac ryanodine receptor activity is altered by oxidizing reagents in either the luminal or cytoplasmic solution

scientific article published on 01 February 1999

Characteristics of two types of chloride channel in sarcoplasmic reticulum vesicles from rabbit skeletal muscle

scientific article

Control of muscle ryanodine receptor calcium release channels by proteins in the sarcoplasmic reticulum lumen

scientific article published on March 2009

Core skeletal muscle ryanodine receptor calcium release complex.

scientific article

Correction: Cardiac ryanodine receptor activation by a high Ca2+ store load is reversed in a reducing cytoplasmic redox environment

scientific article published on November 2016

Cyclization of the intrinsically disordered α1S dihydropyridine receptor II-III loop enhances secondary structure and in vitro function.

scientific article

Delayed contractures induced by external cadmium ions in rat soleus muscle fibres

scientific article published on 01 January 2000

Depolarization accelerates the decay of K+ contractures in rat skeletal muscle fibers

scientific article published on 01 August 1996

Differences in the regulation of RyR2 from human, sheep, and rat by Ca²⁺ and Mg²⁺ in the cytoplasm and in the lumen of the sarcoplasmic reticulum

scientific article

Differential effects of glycerol treatment on membrane capacity and excitation-contraction coupling in toad sartorius fibres

scientific article published on 01 October 1973

Differential effects of thyroid hormone on T-tubules and terminal cisternae in rat muscles: an electrophysiological and morphometric analysis.

scientific article published in June 1986

Dissection of the inhibition of cardiac ryanodine receptors by human glutathione transferase GSTM2-2.

scientific article published on 13 January 2009

Distribution of calcium ATPase in the sarcoplasmic reticulum of fast- and slow-twitch muscles determined with monoclonal antibodies

scientific article published on 01 January 1987

Distribution of potassium and chloride permeability over the surface and T-tubule membranes of mammalian skeletal muscle ⬇️

scientific article published on April 9, 1979

Do independent processes control the activation and inactivation of potassium contracture tension in rat skeletal muscle?

scientific article published on 01 September 1993

Dynamic regulation of ryanodine receptor type 1 (RyR1) channel activity by Homer 1

scientific article published on 17 August 2007

Effect of chloride withdrawal on the geometry of the T-tubules in amphibian and mammalian muscle

scientific article published on 01 January 1982

Effects of an alpha-helical ryanodine receptor C-terminal tail peptide on ryanodine receptor activity: modulation by Homer.

scientific article published on 19 April 2006

Effects of external cadmium ions on excitation-contraction coupling in rat soleus fibres

scientific article published on 01 January 1999

Effects of extracellular calcium concentration and dihydropyridines on contraction in mammalian skeletal muscle.

scientific article published in May 1988

Effects of ivermectin and midecamycin on ryanodine receptors and the Ca2+-ATPase in sarcoplasmic reticulum of rabbit and rat skeletal muscle.

scientific article published in January 1999

Effects of membrane potential on just detectable movement in rat skeletal muscle: effects of denervation

scientific article published on 01 March 1994

Effects of membrane potential on mechanical activation in skeletal muscle.

scientific article published on February 1982

Excitation-contraction coupling and charge movement in denervated rat extensor digitorum longus and soleus muscles

scientific article published on 01 January 1985

Excitation-contraction coupling from the 1950s into the new millennium.

scientific article

Exploiting Peptidomimetics to Synthesize Compounds That Activate Ryanodine Receptor Calcium Release Channels

scientific article published on 28 August 2018

Extra-junctional ryanodine receptors in the terminal cisternae of mammalian skeletal muscle fibres

scientific article published on 01 January 1992

Feet, bridges, and pillars in triad junctions of mammalian skeletal muscle: their possible relationship to calcium buffers in terminal cisternae and T-tubules and to excitation-contraction coupling

scientific article published on 01 July 1989

Fiber types in red and white segments of rat sternomastoid muscle ⬇️

scientific article published on September 1, 1979

Functional and Structural Characterization of a Novel Malignant Hyperthermia-susceptible variant of DHPR-β1a subunit (CACNB1).

scientific article published on 6 December 2017

Functional implications of modifying RyR-activating peptides for membrane permeability.

scientific article

Glutathione transferase M2 variants inhibit ryanodine receptor function in adult mouse cardiomyocytes.

scientific article published on 7 August 2015

Heterogeneity of T-tubule geometry in vertebrate skeletal muscle fibres

scientific article published on 01 June 1984

High-frequency fatigue in rat skeletal muscle: role of extracellular ion concentrations.

scientific article published on August 1995

Immunogold labeling of calcium ATPase in sarcoplasmic reticulum of skeletal muscle: use of 1-nm, 5-nm, and 10-nm gold

scientific article published on 01 October 1993

In vitro modulation of the cardiac ryanodine receptor activity by Homer1.

scientific article

Inactivation of excitation-contraction coupling in rat extensor digitorum longus and soleus muscles.

scientific article

Indentations in the terminal cisternae of amphibian and mammalian skeletal muscle fibers

scientific article published on 01 July 1983

Indentations in the terminal cisternae of denervated rat EDL and soleus muscle fibers

scientific article published on 01 July 1984

Inositol polyphosphates modify the kinetics of a small chloride channel in skeletal muscle sarcoplasmic reticulum

scientific article published on 01 May 1997

Ion channel gating in cardiac ryanodine receptors from the arrhythmic RyR2-P2328S mouse

scientific article published on 21 May 2019

Junctin - the quiet achiever

scientific article

Junctin and triadin each activate skeletal ryanodine receptors but junctin alone mediates functional interactions with calsequestrin

scientific article published on 04 May 2009

K-contractures and membrane potential in mammalian skeletal muscle ⬇️

scientific article published on March 3, 1977

Low resistance junctions in crayfish. Structural changes with functional uncoupling ⬇️

scientific article published on August 1, 1976

Magnesium inhibition of ryanodine-receptor calcium channels: evidence for two independent mechanisms

scientific article published on 01 April 1997

Malignant hyperthermia mutation sites in the Leu2442-Pro2477 (DP4) region of RyR1 (ryanodine receptor 1) are clustered in a structurally and functionally definable area

scientific article published on January 2007

Mechanical activation in dystrophic C57BL mouse muscle.

scientific article

Molecular recognition of the disordered dihydropyridine receptor II-III loop by a conserved spry domain of the type 1 ryanodine receptor.

scientific article

Multiple actions of imperatoxin A on ryanodine receptors: interactions with the II-III loop "A" fragment.

scientific article

Multiple actions of phi-LITX-Lw1a on ryanodine receptors reveal a functional link between scorpion DDH and ICK toxins

scientific article

Multiple actions of the anthracycline daunorubicin on cardiac ryanodine receptors

scientific article published on 22 June 2011

Multiple targets for flecainide action: implications for cardiac arrhythmogenesis

scientific article

Muscle-specific GSTM2-2 on the luminal side of the sarcoplasmic reticulum modifies RyR ion channel activity.

scientific article

Nitric oxide activates or inhibits skeletal muscle ryanodine receptors depending on its concentration, membrane potential and ligand binding.

scientific article

Noninactivating tension in rat skeletal muscle. Effects of thyroid hormone

scientific article

Novel regulators of RyR Ca2+ release channels: insight into molecular changes in genetically-linked myopathies.

scientific article published on 15 August 2006

Paralysis of skeletal muscle by butanedione monoxime, a chemical phosphatase

scientific article published on 01 January 1988

Peptide fragments of the dihydropyridine receptor can modulate cardiac ryanodine receptor channel activity and sarcoplasmic reticulum Ca2+ release.

scientific article published in April 2004

Peptide mimetic compounds can activate or inhibit cardiac and skeletal ryanodine receptors

scientific article published on 10 August 2020

Phosphorylation of skeletal muscle calsequestrin enhances its Ca2+ binding capacity and promotes its association with junctin.

scientific article published in October 2008

Physiology and Pharmacology of Ryanodine Receptor Calcium Release Channels.

scientific article published on 22 February 2017

Porin-type 1 proteins in sarcoplasmic reticulum and plasmalemma of striated muscle fibres

scientific article published on 01 December 1995

Potassium contractures and asymmetric charge movement in extensor digitorum longus and soleus muscles from thyrotoxic rats

scientific article published on 01 August 1987

Potassium contractures and mechanical activation in mammalian skeletal muscles

scientific article published on 01 December 1980

Proteins within the intracellular calcium store determine cardiac RyR channel activity and cardiac output

scientific article published on May 2012

Publisher's Note: Association of FK506 binding proteins with RyR channels - effect of CLIC2 binding on sub-conductance opening and FKBP binding. J. Cell Sci. doi: 10.1242/jcs.204461.

scientific article published on 5 October 2017

Recent advances in understanding the ryanodine receptor calcium release channels and their role in calcium signalling

scientific article published on 27 November 2018

Redox potential and the response of cardiac ryanodine receptors to CLIC-2, a member of the glutathione S-transferase structural family

scientific article published in October 2008

Reduced inhibitory effect of Mg2+ on ryanodine receptor-Ca2+ release channels in malignant hyperthermia.

scientific article

Regions of ryanodine receptors that influence activation by the dihydropyridine receptor β1a subunit

scientific article published on 22 July 2015

Regulation and dysregulation of cardiac ryanodine receptor (RyR2) open probability during diastole in health and disease

scientific article

Regulation of ryanodine receptors by calsequestrin: effect of high luminal Ca2+ and phosphorylation.

scientific article

Regulation of skeletal ryanodine receptors by dihydropyridine receptor II-III loop C-region peptides: relief of Mg2+ inhibition.

scientific article

Regulation of the cardiac muscle ryanodine receptor by glutathione transferases

scientific article

Rods in the terminal cisternae of skeletal muscle

scientific article published on 01 November 1987

Role of some unconserved residues in the "C" region of the skeletal DHPR II-III loop

scientific article

Ryanodine receptor Ca2+ release channel post-translational modification: Central player in cardiac and skeletal muscle disease

scientific article published on 15 May 2018

Ryanodine receptor modification and regulation by intracellular Ca2+ and Mg2+ in healthy and failing human hearts.

scientific article published on 25 January 2017

Ryanodine receptors from rabbit skeletal muscle are reversibly activated by rapamycin

scientific article published on 01 April 1997

Selective effects of an octopus toxin on action potentials.

scientific article published in October 1971

Single channel activity of the ryanodine receptor calcium release channel is modulated by FK-506.

scientific article

Skeletal muscle excitation-contraction coupling: who are the dancing partners?

scientific article

Skeletal muscle ryanodine receptor channels are activated by the fungal metabolite, gliotoxin

scientific article published on 01 June 2000

Slow potassium contractures in mouse limb muscles ⬇️

scientific article published on 01 May 1981

Slow potential changes in mammalian muscle fibers during prolonged hyperpolarization: transport number effects and chloride depletion.

scientific article

Structural and biophysical analyses of the skeletal dihydropyridine receptor β subunit β1a reveal critical roles of domain interactions for stability.

scientific article published on 28 March 2017

Structural and functional characterization of interactions between the dihydropyridine receptor II-III loop and the ryanodine receptor

scientific article published on 01 November 2006

Structure of the Janus protein human CLIC2

scientific article

Subcellular distribution of ryanodine receptor-like and calcium ATPase-like immunoreactivity in brainstem and cerebellar neurones of rat and guinea pig.

scientific article

Subconductance states in single-channel activity of skeletal muscle ryanodine receptors after removal of FKBP12

scientific article

The Anthracycline Metabolite Doxorubicinol Abolishes RyR2 Sensitivity to Physiological Changes in Luminal Ca2+ through an Interaction with Calsequestrin.

scientific article

The GSTM2 C-Terminal Domain Depresses Contractility and Ca2+ Transients in Neonatal Rat Ventricular Cardiomyocytes.

scientific article

The Mu class glutathione transferase is abundant in striated muscle and is an isoform-specific regulator of ryanodine receptor calcium channels

scientific article

The conformation of calsequestrin determines its ability to regulate skeletal ryanodine receptors

scientific article

The contractile properties, histochemistry, ultrastructure and electrophysiology of the cricothyroid and posterior cricoarytenoid muscles in the rat.

scientific article

The cysteine-rich secretory protein domain of Tpx-1 is related to ion channel toxins and regulates ryanodine receptor Ca2+ signaling

scientific article

The dependence of membrane potential on extracellular chloride concentration in mammalian skeletal muscle fibres.

scientific article published in March 1978

The effect of diazepam on potassium contractures, contraction threshold, and resting tension in rat skeletal muscles ⬇️

scientific article published on May 1, 1988

The effects of beta-adrenoceptor activation on contraction in isolated fast- and slow-twitch skeletal muscle fibres of the rat.

scientific article

The elusive role of the SPRY2 domain in RyR1.

scientific article

The inhibitory glutathione transferase M2-2 binding site is located in divergent region 3 of the cardiac ryanodine receptor

scientific article

The membrane capacity of mammalian skeletal muscle fibres.

scientific article published on June 1984

The passive electrical properties of frog skeletal muscle fibres at different sarcomere lengths ⬇️

scientific article published on April 1, 1977

The random-coil 'C' fragment of the dihydropyridine receptor II-III loop can activate or inhibit native skeletal ryanodine receptors.

scientific article published in June 2003

The recombinant dihydropyridine receptor II-III loop and partly structured 'C' region peptides modify cardiac ryanodine receptor activity

scientific article published on February 2005

The relative contributions of the folds and caveolae to the surface membrane of frog skeletal muscle fibres at different sarcomere lengths ⬇️

scientific article published on September 1, 1975

The ryanodine receptor: a pivotal Ca2+ regulatory protein and potential therapeutic drug target.

scientific article published on May 2011

The structure of the C-terminal helical bundle in glutathione transferase M2-2 determines its ability to inhibit the cardiac ryanodine receptor

scientific article published on 22 April 2010

The three-dimensional structural surface of two beta-sheet scorpion toxins mimics that of an alpha-helical dihydropyridine receptor segment

scientific article

The voltage-activation of contraction in skeletal muscle ⬇️

scientific article published on January 1, 1992

The voltage-gated calcium-channel beta subunit: more than just an accessory

scientific article

The β(1a) subunit of the skeletal DHPR binds to skeletal RyR1 and activates the channel via its 35-residue C-terminal tail

scientific article

Three residues in the luminal domain of triadin impact on Trisk 95 activation of skeletal muscle ryanodine receptors.

scientific article published on 5 September 2016

Triadin binding to the C-terminal luminal loop of the ryanodine receptor is important for skeletal muscle excitation contraction coupling

scientific article

Ubiquitous SPRY domains and their role in the skeletal type ryanodine receptor.

scientific article published on 28 April 2009

Ultrastructure of sarcoballs on the surface of skinned amphibian skeletal muscle fibres

scientific article published on December 1, 1992

Unexpected dependence of RyR1 splice variant expression in human lower limb muscles on fiber-type composition.

scientific article

Unique isoform-specific properties of calsequestrin in the heart and skeletal muscle

scientific article published on 18 April 2009

Upper motor neurone modulation of charge movement and mechanical activation in rat skeletal muscle fibres

scientific article published on 01 December 1981

Upper motor neurone modulation of the structure of the terminal cisternae in rat skeletal muscle fibres

scientific article published on 01 December 1981

What we don't know about the structure of ryanodine receptor calcium release channels.

scientific article

ß-Adrenergic stimulation increases RyR2 activity via intracellular Ca2+ and Mg2+ regulation

scientific article

β1a490-508, a 19-residue peptide from C-terminal tail of Cav1.1 β1a subunit, potentiates voltage-dependent calcium release in adult skeletal muscle fibers

scientific article published on February 2014

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