List of works - Umesh T Sankpal

Anti-leukemic response of a NSAID, tolfenamic acid.

scientific article published on 23 April 2013

Anticancer activity of tolfenamic acid in medulloblastoma: a preclinical study.

scientific article published on 18 May 2013

Association of Sp1 and survivin in epithelial ovarian cancer: Sp1 inhibitor and cisplatin, a novel combination for inhibiting epithelial ovarian cancer cell proliferation.

scientific article

Cellular and organismal toxicity of the anti-cancer small molecule, tolfenamic acid: a pre-clinical evaluation.

scientific article published on 10 September 2013

Chemopreventive effects of tolfenamic acid against esophageal tumorigenesis in rats.

scientific article published on 4 January 2011

Combination of 13 cis-retinoic acid and tolfenamic acid induces apoptosis and effectively inhibits high-risk neuroblastoma cell proliferation

scientific article published on 10 August 2015

Combination of tolfenamic acid and curcumin induces colon cancer cell growth inhibition through modulating specific transcription factors and reactive oxygen species

scientific article published on 10 December 2015

DNA methylation inhibitor 5-Aza-2'-deoxycytidine induces reversible genome-wide DNA damage that is distinctly influenced by DNA methyltransferases 1 and 3B.

scientific article published on 8 November 2007

DNMT3B interacts with hSNF2H chromatin remodeling enzyme, HDACs 1 and 2, and components of the histone methylation system

scientific article

Effects of chromatin structure on the enzymatic and DNA binding functions of DNA methyltransferases DNMT1 and Dnmt3a in vitro.

scientific article

Environmental factors in causing human cancers: emphasis on tumorigenesis.

scientific article published on 22 May 2012

Expression of specificity protein transcription factors in pancreatic cancer and their association in prognosis and therapy.

scientific article published on January 2012

Modification of de novo DNA methyltransferase 3a (Dnmt3a) by SUMO-1 modulates its interaction with histone deacetylases (HDACs) and its capacity to repress transcription

scientific article

Mutational analysis of conserved residues in HhaI DNA methyltransferase

scientific article published on June 2002

Relevance of drug metabolizing enzyme activity modulation by tea polyphenols in the inhibition of esophageal tumorigenesis.

scientific article published in September 2011

Role of KCNMA1 gene in breast cancer invasion and metastasis to brain

scientific article published on 29 July 2009

Small molecule tolfenamic acid and dietary spice curcumin treatment enhances antiproliferative effect in pancreatic cancer cells via suppressing Sp1, disrupting NF-kB translocation to nucleus and cell cycle phase distribution

scientific article published on 10 February 2016

Small molecule tolfenamic acid inhibits PC-3 cell proliferation and invasion in vitro, and tumor growth in orthotopic mouse model for prostate cancer.

scientific article

Targeted brain tumor treatment-current perspectives ⬇️

scientific article published on August 17, 2007

Targeting Sp1 transcription factors in prostate cancer therapy.

scientific article published on September 2011

Targeting specificity protein 1 transcription factor and survivin using tolfenamic acid for inhibiting Ewing sarcoma cell growth.

scientific article

Therapeutic applications of NSAIDS in cancer special emphasis on tolfenamic acid ⬇️

scientific article published on January 1, 2011

Tolfenamic acid inhibits neuroblastoma cell proliferation and induces apoptosis: A novel therapeutic agent for neuroblastoma ⬇️

scientific article published on December 28, 2011

Tolfenamic acid inhibits ovarian cancer cell growth and decreases the expression of c-Met and survivin through suppressing specificity protein transcription factors.

scientific article published on 15 April 2011

Tolfenamic acid suppresses cytochrome P450 2E1 expression in mouse liver

scientific article

Tolfenamic acid-induced alterations in genes and pathways in pancreatic cancer cells.

scientific article published on 14 January 2017

Water-assisted dual mode cofactor recognition by HhaI DNA methyltransferase.

scientific article

List of works by Umesh T Sankpal

Anti-leukemic response of a NSAID, tolfenamic acid.

Anticancer activity of tolfenamic acid in medulloblastoma: a preclinical study.

Association of Sp1 and survivin in epithelial ovarian cancer: Sp1 inhibitor and cisplatin, a novel combination for inhibiting epithelial ovarian cancer cell proliferation.

Cellular and organismal toxicity of the anti-cancer small molecule, tolfenamic acid: a pre-clinical evaluation.

Chemopreventive effects of tolfenamic acid against esophageal tumorigenesis in rats.

Combination of 13 cis-retinoic acid and tolfenamic acid induces apoptosis and effectively inhibits high-risk neuroblastoma cell proliferation

Combination of tolfenamic acid and curcumin induces colon cancer cell growth inhibition through modulating specific transcription factors and reactive oxygen species

DNA methylation inhibitor 5-Aza-2'-deoxycytidine induces reversible genome-wide DNA damage that is distinctly influenced by DNA methyltransferases 1 and 3B.

DNMT3B interacts with hSNF2H chromatin remodeling enzyme, HDACs 1 and 2, and components of the histone methylation system

Effects of chromatin structure on the enzymatic and DNA binding functions of DNA methyltransferases DNMT1 and Dnmt3a in vitro.

Environmental factors in causing human cancers: emphasis on tumorigenesis.

Expression of specificity protein transcription factors in pancreatic cancer and their association in prognosis and therapy.

Modification of de novo DNA methyltransferase 3a (Dnmt3a) by SUMO-1 modulates its interaction with histone deacetylases (HDACs) and its capacity to repress transcription

Mutational analysis of conserved residues in HhaI DNA methyltransferase

Relevance of drug metabolizing enzyme activity modulation by tea polyphenols in the inhibition of esophageal tumorigenesis.

Role of KCNMA1 gene in breast cancer invasion and metastasis to brain

Small molecule tolfenamic acid and dietary spice curcumin treatment enhances antiproliferative effect in pancreatic cancer cells via suppressing Sp1, disrupting NF-kB translocation to nucleus and cell cycle phase distribution

Small molecule tolfenamic acid inhibits PC-3 cell proliferation and invasion in vitro, and tumor growth in orthotopic mouse model for prostate cancer.

Targeted brain tumor treatment-current perspectives ⬇️

Targeting Sp1 transcription factors in prostate cancer therapy.

Targeting specificity protein 1 transcription factor and survivin using tolfenamic acid for inhibiting Ewing sarcoma cell growth.

Therapeutic applications of NSAIDS in cancer special emphasis on tolfenamic acid ⬇️

Tolfenamic acid inhibits neuroblastoma cell proliferation and induces apoptosis: A novel therapeutic agent for neuroblastoma ⬇️

Tolfenamic acid inhibits ovarian cancer cell growth and decreases the expression of c-Met and survivin through suppressing specificity protein transcription factors.

Tolfenamic acid suppresses cytochrome P450 2E1 expression in mouse liver

Tolfenamic acid-induced alterations in genes and pathways in pancreatic cancer cells.

Water-assisted dual mode cofactor recognition by HhaI DNA methyltransferase.