List of works by Ken Butcher

A multicenter, randomized, double-blinded, placebo-controlled phase III study of Clot Lysis Evaluation of Accelerated Resolution of Intraventricular Hemorrhage (CLEAR III).

scientific article published on 28 August 2013

A summary of the Canadian Stroke Best Practice Recommendations, Sixth Edition (2018): Updates relevant to prehospital and emergency medicine providers

scientific article published on 01 September 2018

Acute Blood Pressure Management in Intracerebral Hemorrhage: Equipoise Resists an Attack.

scientific article published on 15 November 2016

Acute blood pressure reduction in patients with intracerebral hemorrhage does not result in borderzone region hypoperfusion.

scientific article published on 21 August 2014

Acute stroke imaging. Part I: Fundamentals.

scientific article

Acute stroke thrombolysis following dabigatran reversal using idarucizumab

scientific article published on 01 March 2019

Acute stroke thrombolysis with intravenous tissue plasminogen activator in an Australian tertiary hospital

scientific article published on 01 April 2003

Advanced imaging in acute stroke management-Part I: Computed tomographic.

scientific article published on September 2009

Aggressive blood pressure reduction is not associated with decreased perfusion in leukoaraiosis regions in acute intracerebral hemorrhage patients

scientific article published on 11 March 2019

Ameloblast differentiation in the human developing tooth: effects of extracellular matrices.

scientific article published on 6 March 2010

Amelogenins in human developing and mature dental pulp

scientific article

Apparent diffusion coefficient thresholds do not predict the response to acute stroke thrombolysis.

scientific article published on 3 November 2005

Assessing reperfusion and recanalization as markers of clinical outcomes after intravenous thrombolysis in the echoplanar imaging thrombolytic evaluation trial (EPITHET).

scientific article published on 28 May 2009

Baseline diabetic status and admission blood glucose were poor prognostic factors in the EPITHET trial.

scientific article published on 5 November 2009

Bleeding and infection with external ventricular drainage: a systematic review in comparison with adjudicated adverse events in the ongoing Clot Lysis Evaluating Accelerated Resolution of Intraventricular Hemorrhage Phase III (CLEAR-III IHV) trial

scientific article

Blood pressure management in acute intracerebral hemorrhage: current evidence and ongoing controversies

scientific article published in April 2015

Blood pressure reduction does not reduce perihematoma oxygenation: a CT perfusion study.

scientific article published on 18 September 2013

Blood pressure reduction in hypertensive acute ischemic stroke patients does not affect cerebral blood flow

scientific article published on 08 May 2018

Blood-brain barrier compromise does not predict perihematoma edema growth in intracerebral hemorrhage.

scientific article published on 19 February 2015

Canadian Stroke Best Practice Recommendations for Acute Stroke Management: Prehospital, Emergency Department, and Acute Inpatient Stroke Care, 6th Edition, Update 2018

scientific article published on 18 July 2018

Cardiac and sympathetic effects of middle cerebral artery occlusion in the spontaneously hypertensive rat

scientific article published on 01 September 1993

Cardiac enzyme elevations after stroke: the importance of specificity.

scientific article published in August 2002

Cerebral Perfusion Pressure is Maintained in Acute Intracerebral Hemorrhage: A CT Perfusion Study.

scientific article published on 8 October 2015

Cerebral blood flow measurement following extreme blood pressure reduction in an acute intracerebral hemorrhage patient.

scientific article published on 4 May 2011

Cerebral perfusion and blood pressure do not affect perihematoma edema growth in acute intracerebral hemorrhage

scientific article published on April 2014

Challenges and misconceptions in the aetiology and management of atrial fibrillation-related strokes

scientific article published on 08 July 2015

Clinical-diffusion mismatch predicts the putative penumbra with high specificity

scientific article published on 14 July 2005

Computed Tomographic Perfusion Predicts Poor Outcomes in a Randomized Trial of Endovascular Therapy

scientific article published on 08 May 2018

Cost-effectiveness of targeted thrombolytic therapy for stroke patients using multi-modal CT compared to usual practice

scientific article published in PLoS ONE

DWI Reversal Is Associated with Small Infarct Volume in Patients with TIA and Minor Stroke

scientific article published on 12 December 2013

Dabigatran Therapy in Acute Ischemic Stroke Patients Without Atrial Fibrillation.

scientific article published on 30 July 2015

Dabigatran Treatment of Acute Noncardioembolic Ischemic Stroke

scientific article published on 26 February 2020

Dabigatran assessment in patients with acute complications using routine coagulation assays.

scientific article published in July 2014

Dabigatran following acute transient ischemic attack and minor stroke II (DATAS II).

scientific article

Differential prognosis of isolated cortical swelling and hypoattenuation on CT in acute stroke.

scientific article published in February 2007

Dynamic Evolution of Diffusion-Weighted Imaging Lesions in Patients With Minor Ischemic Stroke.

scientific article published on 16 June 2015

EPITHET

article

Early Rivaroxaban Use After Cardioembolic Stroke May Not Result in Hemorrhagic Transformation: A Prospective Magnetic Resonance Imaging Study

scientific article

Early hematoma retraction in intracerebral hemorrhage is uncommon and does not predict outcome

scientific article published in PLoS ONE

Effect of Recombinant Activated Coagulation Factor VII on Hemorrhage Expansion Among Patients With Spot Sign-Positive Acute Intracerebral Hemorrhage: The SPOTLIGHT and STOP-IT Randomized Clinical Trials

scientific article published on 19 August 2019

Elevated hematocrit is associated with reduced reperfusion and tissue survival in acute stroke.

scientific article published in November 2005

Elevations of diffusion anisotropy are associated with hyper-acute stroke: a serial imaging study.

scientific article

Excellent response to thrombolysis following prolonged basilar artery occlusion with extensive ischemic changes on MRI.

scientific article published on 14 August 2009

Exploring Reperfusion Following Endovascular Thrombectomy

scientific article published on 01 August 2019

Exploring the relationship between ischemic core volume and clinical outcomes after thrombectomy or thrombolysis

scientific article published on 17 June 2019

Factors associated with cognitive decline in transient ischemic attack patients

scientific article published on May 2014

Frequency and temporal profile of poststroke hyperglycemia using continuous glucose monitoring

scientific article published on 01 August 2006

Global Use of Idarucizumab in Clinical Practice: Outcomes of the RE-VECTO Surveillance Program

scientific article published on 30 August 2019

Global White Matter Hypoperfusion on CT Predicts Larger Infarcts and Hemorrhagic Transformation after Acute Ischemia.

scientific article

Glucose Modifies the Effect of Endovascular Thrombectomy in Patients With Acute Stroke

scientific article published on 01 March 2019

Good is not Good Enough: The Benchmark Stroke Door-to-Needle Time Should be 30 Minutes.

scientific article

Images in clinical neuroscience.

scientific article

Impact of stroke care unit on patient outcomes in a community hospital.

scientific article published on 19 November 2013

Improving reperfusion time within the ESCAPE Endovascular Clinical Trial

scientific article published on 30 November 2016

Infarct in a New Territory After Treatment Administration in the ESCAPE Randomized Controlled Trial (Endovascular Treatment for Small Core and Anterior Circulation Proximal Occlusion With Emphasis on Minimizing CT to Recanalization Times).

scientific article

Inflammation in intracerebral hemorrhage: clearly present, but what is its role?

scientific article published in December 2006

Influence of Penumbral Reperfusion on Clinical Outcome Depends on Baseline Ischemic Core Volume.

scientific article published on 8 September 2017

Influence of occlusion site and baseline ischemic core on outcome in patients with ischemic stroke

scientific article published on 01 May 2019

Insular cortical ischemia is independently associated with acute stress hyperglycemia.

scientific article

Insular lesion evokes autonomic effects of stroke in normotensive and hypertensive rats

scientific article published on 01 March 1995

Intensive blood pressure reduction in acute intracerebral hemorrhage: a meta-analysis

scientific article

Interpretation and Implementation of Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial (INTERACT II).

scientific article

Intravenous Thrombolysis May Not Improve Clinical Outcome of Acute Ischemic Stroke Patients Without a Baseline Vessel Occlusion.

scientific article published on 6 June 2018

Ischemia in intracerebral hemorrhage is associated with leukoaraiosis and hematoma volume, not blood pressure reduction.

scientific article published on 28 April 2015

Ischemic core thresholds change with time to reperfusion: A case control study.

scientific article published on 4 December 2017

Letter by Gioia et al regarding article, "Blood pressure-lowering treatment with candesartan in patients with acute hemorrhagic stroke"

scientific article published on 09 December 2014

Low bone mineral density is associated with poor clinical outcome in acute ischemic stroke.

scientific article

Low cerebral blood volume is predictive of diffusion restriction only in hyperacute stroke

scientific article published on 04 November 2010

Lower Blood Pressure Is Not Associated With Decreased Arterial Spin Labeling Estimates of Perfusion in Intracerebral Hemorrhage

scientific article published on 01 June 2019

Magnetic resonance imaging criteria for thrombolysis in acute cerebral infarct.

scientific article

Moving beyond a single perfusion threshold to define penumbra: a novel probabilistic mismatch definition.

scientific article

Multimodal CT in Acute Stroke

scientific article published on 27 July 2019

National Institutes of Health Stroke Scale score is an unreliable predictor of perfusion deficits in acute stroke

scientific article published on 6 April 2015

Novel oral anticoagulant management issues for the stroke clinician

scientific article

One-Year Healthcare Utilization for Patients That Received Endovascular Treatment Compared With Control

scientific article published on 03 June 2019

Oxfordshire community stroke project classification poorly differentiates small cortical and subcortical infarcts.

scientific article published on 23 June 2011

PWI/DWI Mismatch: Better Definition Required ⬇️

scientific article published on October 23, 2003

Pathophysiological determinants of worse stroke outcome in atrial fibrillation.

scientific article

Penumbral Imaging-Based Thrombolysis with Tenecteplase Is Feasible up to 24 Hours after Symptom Onset

scientific article published on 20 August 2018

Penumbral Imaging-Based Thrombolysis with Tenecteplase Is Feasible up to 24 Hours after Symptom Onset.

scientific article published on 31 January 2018

Perfusion MR predicts outcome in high-risk transient ischemic attack/minor stroke: a derivation-validation study.

scientific article published in August 2013

Perfusion computed tomography in patients with stroke thrombolysis

scientific article published on 31 December 2016

Perfusion thresholds in acute stroke thrombolysis.

scientific article published on 31 July 2003

Perihematoma cerebral blood flow is unaffected by statin use in acute intracerebral hemorrhage patients

scientific article

Perihematomal edema in primary intracerebral hemorrhage is plasma derived.

scientific article

Permeability measures predict haemorrhagic transformation after ischemic stroke

scientific article published on 17 May 2020

Persistent poststroke hyperglycemia is independently associated with infarct expansion and worse clinical outcome.

scientific article published on 31 July 2003

Postthrombolysis Blood Pressure Elevation Is Associated With Hemorrhagic Transformation

article

Prehospital systolic blood pressure is higher in acute stroke compared with stroke mimics.

scientific article published on 18 May 2016

Prior events predict cerebrovascular and coronary outcomes in the PROGRESS trial

scientific article

Prognostic evaluation based on cortical vein score difference in stroke.

scientific article

Proposed approach to thrombolysis in dabigatran-treated patients presenting with ischemic stroke.

scientific article

Quantitative Susceptibility Mapping for Following Intracranial Hemorrhage

scientific article published on 19 June 2018

Quantitative susceptibility mapping using a superposed dipole inversion method: Application to intracranial hemorrhage

scientific article published on 28 September 2015

Rapid Assessment and Treatment of Transient Ischemic Attacks and Minor Stroke in Canadian Emergency Departments: Time for a Paradigm Shift.

scientific article

Rapid advanced neuroimaging assessment in acute stroke.

scientific article published on April 2009

Rapid assessment of perfusion-diffusion mismatch.

scientific article published on 6 December 2007

Rationale and design of a randomized trial of early intensive blood pressure lowering on cerebral perfusion parameters in thrombolysed acute ischemic stroke patients

scientific article published on 01 October 2018

Reduction of Diffusion-Weighted Imaging Contrast of Acute Ischemic Stroke at Short Diffusion Times

scientific article

Refining the Perfusion–Diffusion Mismatch Hypothesis

scientific article published on 01 June 2005

Regional very low cerebral blood volume predicts hemorrhagic transformation better than diffusion-weighted imaging volume and thresholded apparent diffusion coefficient in acute ischemic stroke.

scientific article published on 3 December 2009

Relationship between sodium intensity and perfusion deficits in acute ischemic stroke

scientific article published on 01 January 2011

Repeated hemicraniectomy for malignant cerebral edema: getting it right first time.

scientific article

Response to letter regarding article, "serial montreal cognitive assessments demonstrate reversible cognitive impairment in patients with acute transient ischemic attack and minor stroke".

scientific article published on 5 August 2014

Reversible cerebral vasoconstriction syndrome

scientific article published on 01 January 2009

Safety and feasibility of collateral blood flow augmentation after intravenous thrombolysis.

scientific article published on 24 February 2011

Serial montreal cognitive assessments demonstrate reversible cognitive impairment in patients with acute transient ischemic attack and minor stroke.

scientific article published on 22 April 2014

Stroke Mimics Transported by Emergency Medical Services to a Comprehensive Stroke Center: The Magnitude of the Problem

scientific article published on 26 July 2018

Stroke prenotification is associated with shorter treatment times for warfarin-associated intracerebral hemorrhage

scientific article

Surgical clipping or endovascular coiling for unruptured intracranial aneurysms: a pragmatic randomised trial.

scientific article published on 20 June 2017

Telestroke in Northern Alberta: a two year experience with remote hospitals.

scientific article published in November 2010

The Intracerebral Haemorrhage Acutely Decreasing Arterial Pressure Trial: ICH ADAPT.

scientific article

The Intracerebral Hemorrhage Acutely Decreasing Arterial Pressure Trial.

scientific article published on 07 February 2013

The Multiple Causes of Stroke in Atrial Fibrillation: Thinking Broadly

scientific article published on 30 August 2018

The Sneddon syndrome

scientific article published on 01 June 2008

The benefits of intravenous thrombolysis relate to the site of baseline arterial occlusion in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET).

scientific article published on 7 January 2010

The blood pressure paradox in acute ischemic stroke

scientific article published on 18 February 2019

The influence of diabetes mellitus and hyperglycaemia on stroke incidence and outcome.

scientific article

The intracerebral hemorrhage acutely decreasing arterial pressure trial II (ICH ADAPT II) protocol

scientific article

Thrombolysis for concomitant acute stroke and pulmonary embolism

scientific article published on 12 May 2008

Thrombolysis in the developing world: is there a role for streptokinase?

scientific article published on 21 January 2013

Thrombolytic removal of intraventricular haemorrhage in treatment of severe stroke: results of the randomised, multicentre, multiregion, placebo-controlled CLEAR III trial.

scientific article published on 9 January 2017

Too good to treat? ischemic stroke patients with small computed tomography perfusion lesions may not benefit from thrombolysis.

scientific article

Validating a Predictive Model of Acute Advanced Imaging Biomarkers in Ischemic Stroke

scientific article published on 19 January 2017

White matter hyperintensity volume predicts persistent cognitive impairment in transient ischemic attack and minor stroke.

scientific article published on 26 October 2016

Who says "no" to participating in stroke clinical trials and why: an observational study from the Vancouver Stroke Program

scientific article published on 31 May 2019

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