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List of works by Hendrik Simon Schaaf

A Proposed Comprehensive Classification of Tuberculosis Disease Severity in Children ⬇️

scientific article published on April 1, 2012

A decade of experience with Mycobacterium tuberculosis culture from children: a seasonal influence on incidence of childhood tuberculosis.

scientific article published in February 1996

A proposed radiological classification of childhood intra-thoracic tuberculosis.

scientific article

A randomized controlled trial of intermittent compared with daily cotrimoxazole preventive therapy in HIV-infected children.

scientific article published in September 2010

A refined symptom-based approach to diagnose pulmonary tuberculosis in children.

scientific article

A review of the use of ethionamide and prothionamide in childhood tuberculosis

scientific article published on 19 October 2015

Abnormal thyroid function tests in children on ethionamide treatment [Short communication] ⬇️

scientific article published on September 1, 2011

Acquired drug resistance during inadequate therapy in a young child with tuberculosis

scientific article published on 01 August 2014

Adherence to isoniazid preventive chemotherapy: a prospective community based study

scientific article

Adolescents and young adults: a neglected population group for tuberculosis surveillance

scientific article published on 21 February 2018

Adverse effects of oral second-line antituberculosis drugs in children.

scientific article published on 26 July 2016

Antimicrobial resistance in tuberculosis: an international perspective.

scientific article published on October 2006

Antituberculosis drugs in children

scientific article published on 10 June 2015

Assessing the impact of multidrug-resistant tuberculosis in children: an exploratory qualitative study

scientific article

Bacteriologically confirmed tuberculosis in HIV-infected infants: disease spectrum and survival.

scientific article published on June 2011

Caring for children with drug-resistant tuberculosis: practice-based recommendations.

scientific article published on 13 September 2012

Challenges of using new and repurposed drugs for the treatment of multidrug-resistant tuberculosis in children

scientific article

Child and adult spinal tuberculosis at tertiary hospitals in the Western Cape, South Africa: 4-year burden and trend

scientific article published on 28 September 2018

Child health and tuberculosis

scientific article published on 24 March 2014

Childhood drug-resistant tuberculosis in the Western Cape Province of South Africa

scientific article published on 01 May 2006

Childhood tuberculosis: an emerging and previously neglected problem.

scientific article published on September 2010

Children exposed to multidrug-resistant tuberculosis at a home-based day care centre: a contact investigation

scientific article published on November 2014

Clinical management of adults and children with multidrug-resistant and extensively drug-resistant tuberculosis

scientific article

Clinicoradiologic response of neurologic tuberculous mass lesions in children treated with thalidomide.

scientific article

Comparison of diagnostic criteria of tuberculous meningitis in human immunodeficiency virus-infected and uninfected children.

scientific article

Comparison of different treatments for isoniazid-resistant tuberculosis: an individual patient data meta-analysis.

scientific article published in April 2018

Compassionate use of new drugs in children and adolescents with multidrug-resistant and extensively drug-resistant tuberculosis: early experiences and challenges

scientific article published on 23 June 2016

Complementary surveillance strategies are needed to better characterise the epidemiology, care pathways and treatment outcomes of tuberculosis in children

scientific article

Conducting efficacy trials in children with MDR-TB: what is the rationale and how should they be done?

scientific article published in May 2018

Consensus Statement on Research Definitions for Drug-Resistant Tuberculosis in Children ⬇️

scientific article published on April 10, 2013

Correction to: The impact of drug resistance on the risk of tuberculosis infection and disease in child household contacts: a cross sectional study.

scientific article published on 7 November 2017

Cost-effectiveness of home-based vs. in-hospital treatment of paediatric tuberculous meningitis

scientific article published on 01 October 2018

Culture-positive tuberculosis in human immunodeficiency virus type 1-infected children ⬇️

scientific article published on July 1, 1998

Current status of pharmacokinetic and safety studies of multidrug-resistant tuberculosis treatment in children.

scientific article published in May 2018

Danish bacille Calmette-Guérin vaccine-induced disease in human immunodeficiency virus-infected children.

scientific article published on 6 October 2003

Detecting tuberculosis infection in HIV-infected children: a study of diagnostic accuracy, confounding and interaction.

scientific article

Determinants of tuberculosis treatment completion among newborns in a high-burden setting.

scientific article published on March 2014

Diagnosis and Management of Multidrug-Resistant Tuberculosis in Children: A Practical Approach

scientific article published on 17 January 2019

Diagnostic aspects of cervical lymphadenopathy in children in the developing world: a study of 1,877 surgical specimens

scientific article published on 17 April 2003

Diagnostic dilemmas in abdominal tuberculosis in children.

scientific article

Diversity of disease in childhood pulmonary tuberculosis.

scientific article

Dose regimen of para-aminosalicylic acid gastro-resistant formulation (PAS-GR) in multidrug-resistant tuberculosis

scientific article published on 01 April 2014

ERS/WHO Tuberculosis Consilium assistance with extensively drug-resistant tuberculosis management in a child: case study of compassionate delamanid use.

scientific article published on 15 May 2014

Effect of isoniazid prophylaxis on mortality and incidence of tuberculosis in children with HIV: randomised controlled trial.

scientific article published on 3 November 2006

Environmental tobacco smoke exposure increases Mycobacterium tuberculosis infection risk in children ⬇️

scientific article published on November 1, 2011

Epidemiology of invasive Haemophilus influenzae infections in Cape Town, South Africa.

scientific article

Evaluation of young children in household contact with adult multidrug-resistant pulmonary tuberculosis cases

scientific article published on 01 June 1999

Executive Summary: Official American Thoracic Society/Centers for Disease Control and Prevention/Infectious Diseases Society of America Clinical Practice Guidelines: Treatment of Drug-Susceptible Tuberculosis.

scientific article published on October 2016

Failure of chemoprophylaxis with standard antituberculosis agents in child contacts of multidrug-resistant tuberculosis cases.

scientific article published on December 2007

Fine Needle Aspiration Biopsy of Peripheral Lymph Nodes in Children: Practical Experience in a Tertiary Hospital

scientific article published on 04 July 2020

Fluoroquinolones for the treatment of tuberculosis in children.

scientific article published on 14 February 2015

Genome and MIC stability in Mycobacterium tuberculosis and indications for continuation of use of isoniazid in multidrug-resistant tuberculosis.

scientific article published on October 1997

Global shortages of BCG vaccine and tuberculous meningitis in children

scientific article published on 01 January 2019

HIV transmission between two siblings in Africa.

scientific article published in May 2000

High prevalence of drug resistance amongst HIV-exposed and -infected children in a tuberculosis prevention trial.

scientific article published on February 2012

High tuberculosis exposure among neonates in a high tuberculosis and human immunodeficiency virus burden setting ⬇️

scientific article published on June 12, 2012

Impact of Drug Resistance on Clinical Outcome in Children With Tuberculous Meningitis

scientific article published on 01 July 2012

In reply: Acquired drug-resistance because of pharmacokinetic variability in a young child with tuberculosis

scientific article published on 01 November 2014

Induced sputum microbiology in confirming pulmonary tuberculosis in children

scientific article published on 01 September 2011

Isoniazid preventive therapy in HIV-infected and -uninfected children (0 - 14 years).

scientific article published on 04 September 2013

Levofloxacin versus placebo for the prevention of tuberculosis disease in child contacts of multidrug-resistant tuberculosis: study protocol for a phase III cluster randomised controlled trial (TB-CHAMP)

scientific article published on 20 December 2018

Linezolid for the treatment of drug-resistant tuberculosis in children: a review and recommendations.

scientific article published on 27 October 2013

Linezolid-containing regimens for the treatment of drug-resistant tuberculosis in South African children.

scientific article published on 02 October 2012

Long-term linezolid treatment in a young child with extensively drug-resistant tuberculosis.

scientific article published in August 2009

Management of children exposed to multidrug-resistant Mycobacterium tuberculosis

scientific article published on 27 February 2012

Management of multidrug-resistant tuberculosis in children: a survival guide for paediatricians ⬇️

scientific article published on October 14, 2010

Managing multidrug-resistant tuberculosis in children: review of recent developments.

scientific article published on June 2014

Maternal Chest Radiography as Supporting Evidence for the Diagnosis of Tuberculosis in Childhood ⬇️

scientific article published on October 1, 1991

Minimal inhibitory concentration of isoniazid in isoniazid-resistant Mycobacterium tuberculosis isolates from children

scientific article published on 01 March 2007

Minimizing the risk of non-vertical, non-sexual HIV infection in children--beyond mother to child transmission

scientific article

Modelling the cost-effectiveness of strategies to prevent tuberculosis in child contacts in a high-burden setting ⬇️

scientific article published on June 20, 2012

Mycobacterium tuberculosis transmission is not related to household genotype in a setting of high endemicity

scientific article published on 04 March 2009

New and Repurposed Drugs for Pediatric Multidrug-Resistant Tuberculosis. Practice-based Recommendations.

scientific article published on 17 November 2016

Novel application of NIH case definitions in a paediatric tuberculosis contact investigation study

scientific article published on April 2015

Nutritional status and its response to treatment of children, with and without HIV infection, hospitalized for the management of tuberculosis ⬇️

scientific article published on May 1, 2012

Official American Thoracic Society/Centers for Disease Control and Prevention/Infectious Diseases Society of America Clinical Practice Guidelines: Treatment of Drug-Susceptible Tuberculosis.

scientific article published on 10 August 2016

Old and new drugs for the treatment of tuberculosis in children.

scientific article published on 5 June 2007

Opportunities for chemoprophylaxis in children with culture-confirmed tuberculosis ⬇️

scientific article published on January 1, 2011

Optimizing the detection of recent tuberculosis infection in children in a high tuberculosis-HIV burden setting.

scientific article published on April 2015

Outcome of HIV infected children with culture confirmed tuberculosis.

scientific article

Papulonecrotic tuberculid in children. A report of eight patients.

scientific article published on April 1996

Para-aminosalicylic acid plasma concentrations in children in comparison with adults after receiving a granular slow-release preparation.

scientific article published on 21 November 2012

Pediatric TB: issues related to current and future treatment options.

scientific article published on August 2009

Pediatric multidrug-resistant tuberculosis clinical trials: challenges and opportunities

scientific article

Pharmacokinetics and Safety of Ofloxacin in Children with Drug-Resistant Tuberculosis.

scientific article

Pharmacokinetics and safety of moxifloxacin in children with multidrug-resistant tuberculosis.

scientific article

Pharmacokinetics of Rifampin, Isoniazid, Pyrazinamide, and Ethambutol in Infants Dosed According to Revised WHO-Recommended Treatment Guidelines.

scientific article published on 25 January 2016

Pharmacokinetics of isoniazid in low-birth-weight and premature infants.

scientific article published on 3 February 2014

Pharmacokinetics of isoniazid, rifampin, and pyrazinamide in children younger than two years of age with tuberculosis: evidence for implementation of revised World Health Organization recommendations.

scientific article published on 3 October 2011

Pharmacokinetics of ofloxacin and levofloxacin for prevention and treatment of multidrug-resistant tuberculosis in children.

scientific article published on 18 February 2014

Pharmacokinetics, Safety, and Dosing of Novel Pediatric Levofloxacin Dispersible Tablets in Children with Multidrug-Resistant Tuberculosis Exposure

scientific article published on 27 March 2019

Population pharmacokinetics of rifampicin, pyrazinamide and isoniazid in children with tuberculosis: in silico evaluation of currently recommended doses

scientific article published on 31 January 2014

Preventing the spread of multidrug-resistant tuberculosis and protecting contacts of infectious cases

scientific article

Probable Levofloxacin-associated Secondary Intracranial Hypertension in a Child With Multidrug-resistant Tuberculosis.

scientific article published on 11 March 2016

Prospective evaluation of World Health Organization criteria to assist diagnosis of tuberculosis in children.

scientific article published in May 1998

Pyrazinamide plasma concentrations in young children with tuberculosis.

scientific article published in March 2011

Pyridoxal-5-phosphate plasma concentrations in children receiving tuberculosis chemotherapy including isoniazid.

scientific article published on 8 February 2010

Radiology services for children in HIV- and TB-endemic regions: scope for greater collaboration between radiologists and clinicians caring for children.

scientific article

Requirements for the clinical evaluation of new anti-tuberculosis agents in children.

scientific article published in June 2013

Resistant Mycobacterium bovis Bacillus Calmette-Guérin disease: implications for management of Bacillus Calmette-Guérin Disease in human immunodeficiency virus-infected children

scientific article published in May 2004

Revisiting the mutant prevention concentration to guide dosing in childhood tuberculosis.

scientific article published on 9 March 2017

Rifampicin-monoresistant Mycobacterium tuberculosis disease among children in Cape Town, South Africa.

scientific article

Rise in rifampicin-monoresistant tuberculosis in Western Cape, South Africa.

scientific article published on February 2012

Risk of pulmonary tuberculosis in children with congenital heart disease

scientific article published on 01 July 1995

Safety of long-term isoniazid preventive therapy in children with HIV: a comparison of two dosing schedules.

scientific article published on 8 November 2012

Serotypes and antimicrobial susceptibility of Haemophilus influenzae.

scientific article published in December 1994

Short intensified treatment in children with drug-susceptible tuberculous meningitis

scientific article published on March 2014

Stool microscopy and culture to assist the diagnosis of pulmonary tuberculosis in childhood

scientific article published on 01 October 1996

Successful Treatment of a Child With Extensively Drug-Resistant Tuberculous Meningitis.

scientific article

Surveillance of antituberculosis drug resistance among children from the Western Cape Province of South Africa--an upward trend

scientific article published on 05 February 2009

Teaching chest X-ray reading for child tuberculosis suspects.

scientific article

The Role of Xpert MTB/RIF Ultra in Diagnosing Pulmonary Tuberculosis in Children

scientific article published on 01 December 2019

The epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant, extensively drug-resistant, and incurable tuberculosis

scientific article

The first 5 years of the family clinic for HIV at Tygerberg Hospital: family demographics, survival of children and early impact of antiretroviral therapy.

scientific article

The impact of isoniazid preventive therapy and antiretroviral therapy on tuberculosis in children infected with HIV in a high tuberculosis incidence setting ⬇️

scientific article published on April 2, 2011

The influence of dose and N-acetyltransferase-2 (NAT2) genotype and phenotype on the pharmacokinetics and pharmacodynamics of isoniazid.

scientific article published on 16 May 2007

The outcome of infants younger than 6 months requiring ventilation for pneumonia caused by Mycobacterium tuberculosis.

scientific article published in May 2008

The risk of disseminated Bacille Calmette-Guerin (BCG) disease in HIV-infected children

scientific article published in August 2006

The safety and tolerability of the second-line injectable antituberculosis drugs in children.

scientific article

The value of transcranial Doppler imaging in children with tuberculous meningitis

scientific article published on 15 May 2014

Time to act on injectable-free regimens for children with multidrug-resistant tuberculosis

scientific article published on 01 September 2018

Timing of HIV diagnosis in children with tuberculosis managed at a referral hospital in Cape Town, South Africa.

scientific article published in May 2018

Toxicity and tolerability of fluoroquinolone-based preventive therapy for childhood contacts of multidrug-resistant tuberculosis.

scientific article

Transmission of multidrug-resistant tuberculosis.

scientific article published in August 2000

Treatment and outcomes in children with multidrug-resistant tuberculosis: A systematic review and individual patient data meta-analysis

scientific article published on 11 July 2018

Treatment of Drug-Resistant Tuberculosis. An Official ATS/CDC/ERS/IDSA Clinical Practice Guideline

scientific article published on 01 November 2019

Treatment outcomes for children with multidrug-resistant tuberculosis: a systematic review and meta-analysis ⬇️

scientific article published on February 27, 2012

Tuberculosis Disease during Pregnancy and Treatment Outcomes in HIV-Infected and Uninfected Women at a Referral Hospital in Cape Town.

scientific article

Tuberculosis at extremes of age.

scientific article published on 04 June 2010

Tuberculosis in children.

scientific article

Tuberculosis in oncology patients.

scientific article published in June 2008

Tuberculous Pericardial Effusions in Children

scientific article published on 31 October 2017

Tuberculous broncho-esophageal fistula in children: a description of two cases.

scientific article published in April 1998

Tuberculous meningitis and miliary tuberculosis in young children.

scientific article published in February 2004

Twice weekly vs. daily chemotherapy for childhood tuberculosis.

scientific article

Understanding the biology, morbidity and social contexts of adolescent tuberculosis: a prospective observational cohort study protocol (Teen TB)

scientific article published in 2022

Unusual forms of intrathoracic tuberculosis in children and their management.

scientific article

Value of the lateral chest radiograph in tuberculosis in children

scientific article published on 01 January 1994

Xpert MTB/RIF on Stool Is Useful for the Rapid Diagnosis of Tuberculosis in Young Children With Severe Pulmonary Disease

scientific article published on 31 January 2017

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