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List of works by Axel Vater

A mixed mirror-image DNA/RNA aptamer inhibits glucagon and acutely improves glucose tolerance in models of type 1 and type 2 diabetes

scientific article published on 06 June 2013

A novel C5a-neutralizing mirror-image (l-)aptamer prevents organ failure and improves survival in experimental sepsis

scientific article published on 26 July 2013

Bioactive lipids S1P and C1P are prometastatic factors in human rhabdomyosarcoma, and their tissue levels increase in response to radio/chemotherapy

scientific article published on 24 April 2013

Hematopoietic stem and progenitor cell mobilization in mice and humans by a first-in-class mirror-image oligonucleotide inhibitor of CXCL12.

scientific article published on 19 March 2013

Identification and characterization of a mirror-image oligonucleotide that binds and neutralizes sphingosine 1-phosphate, a central mediator of angiogenesis

scientific article published on August 2014

In vivo therapy monitoring of experimental rheumatoid arthritis in rats using near-infrared fluorescence imaging

scientific article published in March 2014

Peripherally circulating ghrelin does not mediate alcohol-induced reward and alcohol intake in rodents

scientific article published in April 2014

SDF-1 inhibition targets the bone marrow niche for cancer therapy

scientific article published on 25 September 2014

Structural basis for the targeting of complement anaphylatoxin C5a using a mixed L-RNA/L-DNA aptamer

scientific article published on 22 April 2015

Targeting complement component 5a promotes vascular integrity and limits airway remodeling

scientific article published on 25 March 2013

Turning mirror-image oligonucleotides into drugs: the evolution of Spiegelmer(®) therapeutics

scientific article published on 16 September 2014