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List of works by Joel Mackay

1H, 13C and 15N backbone and side chain resonance assignments of the N-terminal domain of the histidine kinase inhibitor KipI from Bacillus subtilis

scientific article published on 4 June 2010

1H, 13C and 15N resonance assignments of a C-terminal domain of human CHD1.

scientific article published on 19 August 2015

1H, 15N and 13C assignments of FLIN2, an intramolecular LMO2:ldb1 complex

scientific article published on 01 December 2001

1H, 15N and 13C assignments of FLIN4, an intramolecular LMO4:ldb1 complex

scientific article (publication date: June 2002)

1H, 15N and 13C assignments of an intramolecular Lhx3:ldb1 complex

scientific article published on 01 November 2005

1H, 15N and 13C assignments of an intramolecular Lmo2-LIM2/Ldb1-LID complex.

scientific article published on 19 June 2010

A Novel Purification Procedure for Active Recombinant Human DPP4 and the Inability of DPP4 to Bind SARS-CoV-2

scientific article published on 18 November 2020

A Structural Analysis of DNA Binding by Myelin Transcription Factor 1 Double Zinc Fingers

scientific article

A Transcription Factor Addiction in Leukemia Imposed by the MLL Promoter Sequence.

scientific article

A cis-Proline in  -Hemoglobin Stabilizing Protein Directs the Structural Reorganization of  -Hemoglobin

scientific article

A class of zinc fingers involved in protein-protein interactions biophysical characterization of CCHC fingers from fog and U-shaped.

scientific article published in February 2000

A classic zinc finger from friend of GATA mediates an interaction with the coiled-coil of transforming acidic coiled-coil 3

scientific journal article

A complex mechanism determines polarity of DNA replication fork arrest by the replication terminator complex of Bacillus subtilis.

scientific article

A heme-binding protein produced by Haemophilus haemolyticus inhibits non-typeable Haemophilus influenzae

scientific article published on 02 December 2019

A mass spectrometric investigation of the ability of metal complexes to modulate transcription factor activity

scientific article published on 05 August 2009

A new zinc binding fold underlines the versatility of zinc binding modules in protein evolution

scientific article

A novel haem-binding interface in the 22 kDa haem-binding protein p22HBP.

scientific article published on 14 August 2006

A peptide affinity reagent for isolating an intact and catalytically active multi-protein complex from mammalian cells.

scientific article published on 22 January 2015

A rapid method for assessing the RNA-binding potential of a protein.

scientific article

AHSP (α-haemoglobin-stabilizing protein) stabilizes apo-α-haemoglobin in a partially folded state

scientific article

An erythroid chaperone that facilitates folding of alpha-globin subunits for hemoglobin synthesis

scientific article published in July 2007

Arabinosylation Modulates the Growth-Regulating Activity of the Peptide Hormone CLE40a from Soybean

scientific article

Assessment of the robustness of a serendipitous zinc binding fold: mutagenesis and protein grafting

scientific article published in February 2005

Backbone and side-chain assignments of a tethered complex between LMO4 and DEAF-1.

scientific article published on 16 February 2013

Backbone and sidechain 1H, 13C and 15N chemical shift assignments of the hydrophobin DewA from Aspergillus nidulans ⬇️

scientific article published on August 4, 2011

Beyond DNA: zinc finger domains as RNA-binding modules

scientific article published on 01 January 2010

Binding of the CHD4 PHD2 finger to histone H3 is modulated by covalent modifications

scientific article published on 25 September 2009

Biophysical characterization of the alpha-globin binding protein alpha-hemoglobin stabilizing protein

scientific article

Bivalent recognition of nucleosomes by the tandem PHD fingers of the CHD4 ATPase is required for CHD4-mediated repression ⬇️

scientific article published on January 3, 2012

Bromodomain protein Brd3 associates with acetylated GATA1 to promote its chromatin occupancy at erythroid target genes

scientific article (publication date: 31 May 2011)

CCHX zinc finger derivatives retain the ability to bind Zn(II) and mediate protein-DNA interactions

scientific article (publication date: 25 July 2003)

CHD4 Is a Peripheral Component of the Nucleosome Remodeling and Deacetylase Complex

scientific article published on 27 May 2016

CHD4 slides nucleosomes by decoupling entry- and exit-side DNA translocation

scientific article published on 23 March 2020

CSL: a notch above the rest

scientific article published on 20 July 2005

Ca2+-induced PRE-NMR changes in the troponin complex reveal the possessive nature of the cardiac isoform for its regulatory switch.

scientific article

Characterization of a family of RanBP2-type zinc fingers that can recognize single-stranded RNA.

scientific article

Characterization of the conserved interaction between GATA and FOG family proteins

scientific article

Comparative structure-function analysis of bromodomain and extraterminal motif (BET) proteins in a gene-complementation system

scientific article published on 02 December 2019

Conformational stability and DNA binding specificity of the cardiac T-box transcription factor Tbx20.

scientific article published on 3 May 2009

Crystal Structures of Flax Rust Avirulence Proteins AvrL567-A and -D Reveal Details of the Structural Basis for Flax Disease Resistance Specificity

scientific article

Crystal and solution structures of a superantigen from Yersinia pseudotuberculosis reveal a jelly-roll fold

scientific article

Crystal structure of the Melampsora lini effector AvrP reveals insights into a possible nuclear function and recognition by the flax disease resistance protein P.

scientific article published on 17 August 2017

Crystallization of a ZRANB2-RNA complex.

scientific article published on 28 November 2008

Cyclic peptides can engage a single binding pocket through highly divergent modes

scientific article published on 12 October 2020

DNA-binding studies of XSPTSPSZ, derivatives of the intercalating heptad repeat of RNA polymerase II ⬇️

scientific article published on October 5, 1997

Designed metal-binding sites in biomolecular and bioinorganic interactions.

scientific article published on 12 June 2008

Determinants of affinity and specificity in RNA-binding proteins.

scientific article published on 13 June 2016

Determination of ribonuclease sequence-specificity using Pentaprobes and mass spectrometry.

scientific article

Development of a sensitive peptide-based immunoassay: application to detection of the Jun and Fos oncoproteins.

scientific article

Effects of calcium binding and the hypertrophic cardiomyopathy A8V mutation on the dynamic equilibrium between closed and open conformations of the regulatory N-domain of isolated cardiac troponin C

scientific article

Engineering a protein scaffold from a PHD finger

scientific article

Engineering specificity changes on a RanBP2 zinc finger that binds single-stranded RNA.

scientific article published on 9 July 2014

Escherichia coli glucuronylsynthase: an engineered enzyme for the synthesis of beta-glucuronides.

scientific article

Evolution of quaternary structure in a homotetrameric enzyme

scientific article

Exploring the suitability of RanBP2-type Zinc Fingers for RNA-binding protein design

scientific article published on 21 February 2019

Expression, purification and DNA-binding properties of zinc finger domains of DOF proteins from Arabidopsis thaliana.

scientific article published on 28 January 2018

GATA-1: one protein, many partners.

scientific article

GATAD2B-associated neurodevelopmental disorder (GAND): clinical and molecular insights into a NuRD-related disorder

scientific article published on 17 January 2020

Grb7 SH2 domain structure and interactions with a cyclic peptide inhibitor of cancer cell migration and proliferation

scientific article

Grb7-SH2 domain dimerisation is affected by a single point mutation

scientific article

Hop is an unusual homeobox gene that modulates cardiac development

scientific article (publication date: 20 September 2002)

IP3-4 kinase Arg1 regulates cell wall homeostasis and surface architecture to promote clearance of Cryptococcus neoformans infection in a mouse model.

scientific article published on 4 October 2017

Identification of the key LMO2-binding determinants on Ldb1.

scientific article published on 20 March 2006

Ikaros: a key regulator of haematopoiesis

scientific article (publication date: October 2002)

Implementing the LIM code: the structural basis for cell type-specific assembly of LIM-homeodomain complexes

scientific article

Insight into the Architecture of the NuRD Complex: STRUCTURE OF THE RbAp48-MTA1 SUBCOMPLEX

scientific article

Insights into association of the NuRD complex with FOG-1 from the crystal structure of an RbAp48·FOG-1 complex

scientific article

Interdomain orientation of cardiac troponin C characterized by paramagnetic relaxation enhancement NMR reveals a compact state

scientific article published on September 2012

Interfacial Asparagine Residues within an Amide Tetrad Contribute to Max Helix-Loop-Helix Leucine Zipper Homodimer Stability

scientific article published on 01 December 2000

Involvement of the N-finger in the self-association of GATA-1.

scientific article published in November 1998

Is there a telltale RH fingerprint in zinc fingers that recognizes methylated CpG dinucleotides?

scientific article published on 01 September 2013

It takes two to tango: the structure and function of LIM, RING, PHD and MYND domains.

scientific article

Key residues characteristic of GATA N-fingers are recognized by FOG.

scientific article

Macromolecular NMR spectroscopy for the non-spectroscopist: beyond macromolecular solution structure determination

scientific article published on 28 January 2011

Macromolecular NMR spectroscopy for the non‐spectroscopist ⬇️

scientific article published on January 28, 2011

Measuring protein self-association using pulsed-field-gradient NMR spectroscopy: application to myosin light chain 2

scientific article published on 01 November 1995

Modular Assembly of RanBP2-Type Zinc Finger Domains to Target Single-Stranded RNA

scientific article published on 19 April 2012

Molecular analysis of the interaction between the hematopoietic master transcription factors GATA-1 and PU.1.

scientific article published on 20 July 2006

Molecular mechanism of AHSP-mediated stabilization of alpha-hemoglobin

scientific article

Mutations in cardiac T-box factor gene TBX20 are associated with diverse cardiac pathologies, including defects of septation and valvulogenesis and cardiomyopathy

scientific article

New Insights into DNA Recognition by Zinc Fingers Revealed by Structural Analysis of the Oncoprotein ZNF217

scientific article

PWWP2A binds distinct chromatin moieties and interacts with an MTA1-specific core NuRD complex

scientific article published in Nature Communications

Paris-Trousseau thrombocytopenia is phenocopied by the autosomal recessive inheritance of a DNA-binding domain mutation in FLI1.

scientific article

Peppy: A virtual reality environment for exploring the principles of polypeptide structure

scientific article published on 11 November 2019

Plant Homeodomain (PHD) Fingers of CHD4 Are Histone H3-binding Modules with Preference for Unmodified H3K4 and Methylated H3K9

scientific article

Probing site specificity of DNA binding metallointercalators by NMR spectroscopy and molecular modeling.

scientific article published on April 2001

Promiscuous DNA-binding of a mutant zinc finger protein corrupts the transcriptome and diminishes cell viability

scientific article

Protein interactions: is seeing believing?

scientific article published on 05 November 2007

Protein-protein interactions: Analysis of a false positive GST pulldown result

scientific article published on 02 June 2011

Receptor homodimerization plays a critical role in a novel dominant negative P2RY12 variant identified in a family with severe bleeding.

scientific article published on 8 November 2017

Refinement of the subunit interaction network within the nucleosome remodelling and deacetylase (NuRD) complex.

scientific article

Role of alpha-hemoglobin-stabilizing protein in normal erythropoiesis and beta-thalassemia

scientific article

Self-assembly of functional, amphipathic amyloid monolayers by the fungal hydrophobin EAS

scientific article

Semisynthesis of an evasin from tick saliva reveals a critical role of tyrosine sulfation for chemokine binding and inhibition

scientific article published on 27 May 2020

Siah ubiquitin ligase is structurally related to TRAF and modulates TNF-alpha signaling

scientific article

Site-selective photocatalytic functionalization of peptides and proteins at selenocysteine

scientific article published in 2022

Site-specific phosphorylation of tau inhibits amyloid-β toxicity in Alzheimer's mice

scientific article

Solution Structure of a Recombinant Type I Sculpin Antifreeze Protein†,‡

scientific article published on 01 February 2005

Solution structure of a tethered Lmo2LIM2/Ldb1LIDcomplex

scientific article

Solution structure of the LIM-homeodomain transcription factor complex Lhx3/Ldb1 and the effects of a pituitary mutation on key Lhx3 interactions

scientific article

Solution structure of the THAP domain from Caenorhabditis elegans C-terminal binding protein (CtBP)

scientific article

Solution structures of two CCHC zinc fingers from the FOG family protein U-shaped that mediate protein-protein interactions

scientific article

Sticky fingers: zinc-fingers as protein-recognition motifs

scientific article

Structural Basis for Hemoglobin Capture by Staphylococcus aureus Cell-surface Protein, IsdH

scientific article

Structural analysis of MED-1 reveals unexpected diversity in the mechanism of DNA recognition by GATA-type zinc finger domains

scientific article

Structural analysis of hydrophobins

scientific article

Structural and functional analysis of the Josephin domain of the polyglutamine protein ataxin-3

article

Structural basis for the recognition of ldb1 by the N-terminal LIM domains of LMO2 and LMO4

scientific article

Structural basis of simultaneous recruitment of the transcriptional regulators LMO2 and FOG1/ZFPM1 by the transcription factor GATA1

scientific article

Structural basis of the interaction of the breast cancer oncogene LMO4 with the tumour suppressor CtIP/RBBP8

scientific article

Structure and inhibition of orotidine 5'-monophosphate decarboxylase from Plasmodium falciparum

scientific article

Structure of oxidized alpha-haemoglobin bound to AHSP reveals a protective mechanism for haem

scientific article published in June 2005

Structure of the Hemoglobin-IsdH Complex Reveals the Molecular Basis of Iron Capture byStaphylococcus aureus

scientific article

Synthesis of the bacteriocin glycopeptide sublancin 168 and S-glycosylated variants

scientific article published on 28 March 2012

TC-1 is a novel tumorigenic and natively disordered protein associated with thyroid cancer

scientific article

The BRD3 ET domain recognizes a short peptide motif through a mechanism that is conserved across chromatin remodelers and transcriptional regulators.

scientific article published on 22 March 2018

The Bacillus subtilis cell division proteins FtsL and DivIC are intrinsically unstable and do not interact with one another in the absence of other septasomal components.

scientific article

The Binding of Syndapin SH3 Domain to Dynamin Proline-rich Domain Involves Short and Long Distance Elements

scientific article published on 18 February 2016

The Chromatin Remodelling Protein CHD1 Contains a Previously Unrecognised C-Terminal Helical Domain.

scientific article

The Cys3-Cys4 loop of the hydrophobin EAS is not required for rodlet formation and surface activity

scientific article

The Identification and Structure of an N-Terminal PR Domain Show that FOG1 Is a Member of the PRDM Family of Proteins

scientific article (publication date: 2014)

The MTA1 subunit of the nucleosome remodeling and deacetylase complex can recruit two copies of RBBP4/7.

scientific article

The N-terminal Region of Chromodomain Helicase DNA-binding Protein 4 (CHD4) Is Essential for Activity and Contains a High Mobility Group (HMG) Box-like-domain That Can Bind Poly(ADP-ribose).

scientific article

The N-terminal zinc finger of the erythroid transcription factor GATA-1 binds GATC motifs in DNA.

scientific article

The NuRD complex and macrocephaly associated neurodevelopmental disorders

scientific article published on 18 November 2019

The detection and quantitation of protein oligomerization

scientific article published on January 2012

The dimerization and topological specificity functions of MinE reside in a structurally autonomous C-terminal domain.

scientific article

The hydrophobic domain 26 of human tropoelastin is unstructured in solution

scientific article published in May 2005

The multi-zinc finger protein ZNF217 contacts DNA through a two-finger domain

scientific article published on 11 September 2011

The prospects for designer single-stranded RNA-binding proteins ⬇️

scientific article published on February 27, 2011

The stoichiometry and interactome of the Nucleosome Remodeling and Deacetylase (NuRD) complex are conserved across multiple cell lines

scientific article published on 19 March 2019

The structure of a truncated phosphoribosylanthranilate isomerase suggests a unified model for evolution of the (βα)8 barrel fold

scientific article

The structure of an LIM-only protein 4 (LMO4) and Deformed epidermal autoregulatory factor-1 (DEAF1) complex reveals a common mode of binding to LMO4.

scientific article

The structure of versutoxin (delta-atracotoxin-Hv1) provides insights into the binding of site 3 neurotoxins to the voltage-gated sodium channel

scientific article

The uncharacterized bacterial protein YejG has the same architecture as domain III of elongation factor G

scientific article published on 22 April 2019

The yeast transcription elongation factor Spt4/5 is a sequence-specific RNA binding protein

scientific article

The zinc fingers of YY1 bind single-stranded RNA with low sequence specificity

scientific article

The zinc fingers of the SR-like protein ZRANB2 are single-stranded RNA-binding domains that recognize 5' splice site-like sequences

scientific article

Thermostable small-molecule inhibitor of angiogenesis and vascular permeability that suppresses a pERK-FosB/ΔFosB-VCAM-1 axis

scientific article published on 29 July 2020

Toward an estimation of binding constants in aqueous solution: studies of associations of vancomycin group antibiotics

scientific article

Transcription factor seeks DNA-cognate site preferred.

scientific article published on 12 December 2013

Transcriptional cofactors of the FOG family interact with GATA proteins by means of multiple zinc fingers

scientific article

Trim58 degrades Dynein and regulates terminal erythropoiesis

scientific article published on 18 September 2014

Two-state conformational equilibrium in the Par-4 leucine zipper domain.

scientific article published on August 2010

Two-timing zinc finger transcription factors liaising with RNA.

scientific article published on 07 March 2012

Type I shorthorn sculpin antifreeze protein: recombinant synthesis, solution conformation, and ice growth inhibition studies.

scientific article

Ubiquitin fusion constructs allow the expression and purification of multi-KOW domain complexes of the Saccharomyces cerevisiae transcription elongation factor Spt4/5.

scientific article published on 21 May 2014

Use of altered specificity mutants to probe a specific protein-protein interaction in differentiation: the GATA-1:FOG complex

scientific article published on 01 February 1999

Whaddaya Know: A Guide to Uncertainty and Subjectivity in Structural Biology.

scientific article published on 11 January 2017

Zinc fingers are known as domains for binding DNA and RNA. Do they also mediate protein-protein interactions?

scientific article published on 01 December 2006

Zinc fingers as protein recognition motifs: structural basis for the GATA-1/friend of GATA interaction

scientific article

dCas9-based epigenome editing suggests acquisition of histone methylation is not sufficient for target gene repression.

scientific article published on September 2017

¹H, ¹³C and ¹⁵N resonance assignments of an N-terminal domain of CHD4.

scientific article

¹H, ¹⁵N and ¹³C assignments of an intramolecular LMO4-LIM1/CtIP complex

scientific article published on 4 June 2011

α-Hemoglobin-stabilizing protein (AHSP) perturbs the proximal heme pocket of oxy-α-hemoglobin and weakens the iron-oxygen bond.

scientific article published on 21 May 2013

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