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List of works by Douglas H Thamm

A temporary indwelling intravascular aphaeretic system for in vivo enrichment of circulating tumor cells

scientific article published on 01 April 2019

Alternating Rabacfosadine/Doxorubicin: Efficacy and Tolerability in Naïve Canine Multicentric Lymphoma.

scientific article

An orthotopic, postsurgical model of luciferase transfected murine osteosarcoma with spontaneous metastasis.

scientific article published on 7 March 2010

Association of blood monocyte and lymphocyte count and disease-free interval in dogs with osteosarcoma

scientific article published on 14 September 2010

Auranofin improves overall survival when combined with standard of care in a pilot study involving dogs with osteosarcoma

scientific article published on 23 August 2019

Autophagy and cancer therapy

scientific article

Bacterial Killing Activity of Polymorphonuclear Myeloid-Derived Suppressor Cells Isolated From Tumor-Bearing Dogs

scientific article published on 10 October 2019

Biological and molecular characterization of a canine hemangiosarcoma-derived cell line.

scientific article published on 25 October 2005

Bisphosphonate conjugation for bone specific drug targeting.

scientific article published on 3 July 2018

Canine Cancer: Strategies in Experimental Therapeutics

scientific article published on 15 November 2019

Canine Cutaneous Plasmacytosis: 21 Cases (2005-2015).

scientific article published on 17 May 2017

Canine sarcomas as a surrogate for the human disease.

scientific article published on 26 January 2018

Carcinoma of the apocrine glands of the anal sac in dogs: 113 cases (1985-1995).

scientific article published in September 2003

Changes in cell shape are correlated with metastatic potential in murine and human osteosarcomas.

scientific article published on 12 February 2016

Characterization of a low expression haplotype in canine glutathione S-transferase (GSTT1) and its prevalence in golden retrievers.

scientific article published on 25 August 2017

Click Conjugation of Cloaked Peptide Ligands to Microbubbles

scientific article published on 11 April 2018

Clinical and Immunomodulatory Effects of Toceranib Combined with Low‐Dose Cyclophosphamide in Dogs with Cancer ⬇️

scientific article published on February 4, 2012

Clinical outcome of partial cystectomy for transitional cell carcinoma of the canine bladder

scientific article published on 20 February 2017

Clinical, Pathological, and Ethical Considerations for the Conduct of Clinical Trials in Dogs with Naturally Occurring Cancer: A Comparative Approach to Accelerate Translational Drug Development

scientific article published on 01 December 2018

Combination chemotherapy with L-asparaginase, lomustine, and prednisone for relapsed or refractory canine lymphoma

scientific article published on 01 January 2007

Combination chemotherapy with continuous L-asparaginase, lomustine, and prednisone for relapsed canine lymphoma.

scientific article published on 11 August 2009

Comparative analysis of survivin expression in untreated and relapsed canine lymphoma.

scientific article published in July 2008

Comparative oncology approach to drug repurposing in osteosarcoma

scientific article published on 26 March 2018

Comparative pharmacokinetic properties and antitumor activity of the marine HDACi Largazole and Largazole peptide isostere

scientific article

Comparison of carboplatin and doxorubicin-based chemotherapy protocols in 470 dogs after amputation for treatment of appendicular osteosarcoma

scientific article published on 10 February 2014

Comparison of fluid types for resuscitation after acute blood loss in mallard ducks (Anas platyrhynchos)

scientific article published on 01 October 2009

Concurrent use of rabacfosadine and L-asparaginase for relapsed or refractory multicentric lymphoma in dogs

scientific article published on 16 February 2020

Correlation of nodal mast cells with clinical outcome in dogs with mast cell tumour and a proposed classification system for the evaluation of node metastasis.

scientific article published on 27 August 2014

Cyclooxygenase-2 expression in equine tumors

scientific article published on 01 November 2008

Development of a limited-sampling model for prediction of doxorubicin exposure in dogs.

scientific article published on 3 July 2012

Development of an in vitro model of acquired resistance to toceranib phosphate (Palladia®) in canine mast cell tumor.

scientific article

Diagnostic accuracy of pre-treatment biopsy for grading soft tissue sarcomas in dogs.

scientific article

Disease distribution in canine patients with acanthocytosis: 123 cases.

scientific article published in December 2013

Dose-escalating vinblastine for the treatment of canine mast cell tumour.

scientific article published in June 2008

Doxorubicin and cyclophosphamide for the treatment of canine lymphoma: a randomized, placebo-controlled study.

scientific article

Drug dose and drug choice: Optimizing medical therapy for veterinary cancer

scientific article published on 05 September 2019

Elevated serum thymidine kinase activity in canine splenic hemangiosarcoma*.

scientific article

Epidermal growth factor enhances the malignant phenotype in canine mammary carcinoma cell lines.

scientific article

Epithelial Cell Adhesion Molecule Expression in Canine Tumours

scientific article published on 24 August 2016

Evaluation of a 15-week CHOP protocol for the treatment of canine multicentric lymphoma.

scientific article published on 2 May 2012

Evaluation of a xenogeneic VEGF vaccine in dogs with soft tissue sarcoma

scientific article published on 14 February 2007

Evaluation of prognostic factors associated with outcome in dogs with multiple cutaneous mast cell tumors treated with surgery with and without adjuvant treatment: 54 cases (1998-2004).

scientific article published in January 2006

Expression and function of survivin in canine osteosarcoma.

scientific article

Expression of Phosphorylated KIT in Canine Mast Cell Tumor.

scientific article published on January 2017

GS-9219/VDC-1101--a prodrug of the acyclic nucleotide PMEG has antitumor activity in spontaneous canine multiple myeloma.

scientific article published on 25 January 2014

Genomic instability and telomere fusion of canine osteosarcoma cells.

scientific article

Geographical differences in survival of dogs with non-Hodgkin lymphoma treated with a CHOP based chemotherapy protocol

scientific article published on 17 April 2017

Glucose transporter 1 expression in canine osteosarcoma.

scientific article published in June 2008

Glycolysis inhibition by 2-deoxy-D-glucose reverts the metastatic phenotype in vitro and in vivo.

scientific article

HES1, a target of Notch signaling, is elevated in canine osteosarcoma, but reduced in the most aggressive tumors

scientific article

Human granulocyte-macrophage colony-stimulating factor DNA cationic-lipid complexed autologous tumour cell vaccination in the treatment of canine B-cell multicentric lymphoma

scientific article published on 01 December 2007

IGF-1 receptor contributes to the malignant phenotype in human and canine osteosarcoma

scientific article published on May 2004

Imatinib mesylate inhibits platelet-derived growth factor activity and increases chemosensitivity in feline vaccine-associated sarcoma.

scientific article published on 17 April 2004

Impact of Toceranib/Piroxicam/Cyclophosphamide Maintenance Therapy on Outcome of Dogs with Appendicular Osteosarcoma following Amputation and Carboplatin Chemotherapy: A Multi-Institutional Study

scientific article published on 29 April 2015

Impact of telomerase status on canine osteosarcoma patients.

scientific article published on 25 August 2008

In vitro antineoplastic effects of auranofin in canine lymphoma cells.

scientific article

In vitro effects of PI3K/mTOR inhibition in canine hemangiosarcoma

scientific article published on 16 July 2018

Increased monocyte chemotactic protein-1 concentration and monocyte count independently associate with a poor prognosis in dogs with lymphoma

scientific article published on 10 September 2010

Induction of VEGF by tepoxalin does not lead to increased tumour growth in a canine osteosarcoma xenograft.

scientific article published on 13 September 2010

Interactions between radiation therapy and immunotherapy: the best of two worlds?

scientific article published on 01 December 2006

Interleukin-11 receptor alpha is expressed on canine osteosarcoma.

scientific article published on June 2010

Intralesional lipid-complexed cytokine/superantigen immunogene therapy for spontaneous canine tumors

scientific article published on 27 May 2003

Intrinsic Radiosensitivity and Cellular Characterization of 27 Canine Cancer Cell Lines

scientific article

Ivermectin inhibits canine mammary tumor growth by regulating cell cycle progression and WNT signaling

scientific article published on 02 August 2019

Launching a novel preclinical infrastructure: comparative oncology trials consortium directed therapeutic targeting of TNFalpha to cancer vasculature

scientific article

Low-dose cyclophosphamide selectively decreases regulatory T cells and inhibits angiogenesis in dogs with soft tissue sarcoma.

scientific article published on 7 July 2011

Lung tumor development and spontaneous regression in lambs coinfected with Jaagsiekte sheep retrovirus and ovine lentivirus.

scientific article published in January 2010

Maintenance therapy with toceranib following doxorubicin-based chemotherapy for canine splenic hemangiosarcoma

scientific article published on 11 June 2015

Malignant mesenchymoma with widespread metastasis including bone marrow involvement in a dog.

scientific article

Multicenter prospective trial of hypofractionated radiation treatment, toceranib, and prednisone for measurable canine mast cell tumors.

scientific article published on 19 December 2011

NOD/SCID mouse model of canine T-cell lymphoma with humoral hypercalcaemia of malignancy: cytokine gene expression profiling and in vivo bioluminescent imaging

scientific article

Novel Treatments for Lymphoma

scientific article published on 29 May 2019

Novel acyclic nucleotide analogues GS-343074 and GS-424044 demonstrate antiproliferative and pro-apoptotic activity in canine neoplastic cell lines.

scientific article published on 15 May 2013

Optofluidic intracavity spectroscopy of canine hemangiosarcoma.

scientific article

Outcome and prognostic factors following adjuvant prednisone/vinblastine chemotherapy for high-risk canine mast cell tumour: 61 cases

scientific article published on 01 June 2006

Perspectives from man's best friend: National Academy of Medicine's Workshop on Comparative Oncology.

scientific article published on February 2016

Phase I clinical trial and pharmacodynamic evaluation of combination hydroxychloroquine and doxorubicin treatment in pet dogs treated for spontaneously occurring lymphoma

scientific article

Phase I pharmacokinetic and pharmacodynamic evaluation of combined valproic acid/doxorubicin treatment in dogs with spontaneous cancer.

scientific article

Phase II clinical evaluation of lomustine chemotherapy for feline vaccine‐associated sarcoma ⬇️

scientific article published on October 17, 2011

Phase II evaluation of VDC-1101 in canine cutaneous T-cell lymphoma

scientific article published on September 2014

Phosphorylated KIT as a predictor of outcome in canine mast cell tumours treated with toceranib phosphate or vinblastine

scientific article published on 31 July 2019

Pilot study utilizing Fluorine-18 fluorodeoxyglucose-positron emission tomography/computed tomography for glycolytic phenotyping of canine mast cell tumors

scientific article published on 23 March 2018

Plasma synthesis of carbon magnetic nanoparticles and immobilization of doxorubicin for targeted drug delivery.

scientific article

Polymer-modified gadolinium metal-organic framework nanoparticles used as multifunctional nanomedicines for the targeted imaging and treatment of cancer.

scientific article published in April 2009

Postsurgical Outcome in Cats with Exocrine Pancreatic Carcinoma: Nine Cases (2007-2016)

scientific article published on 24 July 2018

Preclinical evaluation of oncolytic vaccinia virus for therapy of canine soft tissue sarcoma

scientific article (publication date: 2012)

Preclinical study of dolastatin-10 in dogs with spontaneous neoplasia

scientific article published on 18 December 2001

Prednisone and vinblastine chemotherapy for canine mast cell tumor--41 cases (1992-1997)

scientific article published on 01 September 1999

Preliminary evidence for biologic activity of toceranib phosphate (Palladia(®)) in solid tumours.

scientific article published on June 2011

Prognostic and predictive significance of KIT protein expression and c-kit gene mutation in canine cutaneous mast cell tumours: A consensus of the Oncology-Pathology Working Group

scientific article published on 09 July 2019

Prognostic significance of circulating microRNA-214 and -126 in dogs with appendicular osteosarcoma receiving amputation and chemotherapy

scientific article published on 25 January 2019

Prognostic value of fluorine flourodeoxyglucose positron emission tomography/computed tomography in dogs with appendicular osteosarcoma

scientific article published on 15 February 2019

Prospective evaluation of flow cytometric characteristics, histopathologic diagnosis and clinical outcome in dogs with naïve B-cell lymphoma treated with a 19-week CHOP protocol

scientific article published on 04 November 2019

Prospective evaluation of toceranib phosphate in metastatic canine osteosarcoma.

scientific article published on 15 June 2017

Proteus mirabilis inhibits cancer growth and pulmonary metastasis in a mouse breast cancer model.

scientific article

Pulse-Administered Toceranib Phosphate Plus Lomustine for Treatment of Unresectable Mast Cell Tumors in Dogs

scientific article published on 25 June 2015

RT-PCR-based tyrosine kinase display profiling of canine melanoma: IGF-1 receptor as a potential therapeutic target.

scientific article

Rabacfosadine for relapsed canine B-cell lymphoma: Efficacy and adverse event profiles of 2 different doses.

scientific article published on 11 September 2017

Recommended Guidelines for the Conduct and Evaluation of Prognostic Studies in Veterinary Oncology

scientific article published on 27 July 2010

Relative biological effectiveness in canine osteosarcoma cells irradiated with accelerated charged particles

scientific article published on 30 June 2016

Response evaluation criteria for solid tumours in dogs (v1.0): a Veterinary Cooperative Oncology Group (VCOG) consensus document.

scientific article

Retrospective analysis for treatment of naïve canine multicentric lymphoma with a 15-week, maintenance-free CHOP protocol.

scientific article published on 17 August 2015

Retrospective evaluation of doxorubicin-piroxicam combination for the treatment of transitional cell carcinoma in dogs

scientific article published on 03 January 2013

Serum 25-hydroxyvitamin D concentrations in dogs - correlation with health and cancer risk

scientific article published on 08 July 2014

Serum vascular endothelial growth factor concentrations and postsurgical outcome in dogs with osteosarcoma.

scientific article

Somatic inactivating PTPRJ mutations and dysregulated pathways identified in canine malignant melanoma by integrated comparative genomic analysis

scientific article published on 06 September 2018

Substitution of mitoxantrone for doxorubicin in a multidrug chemotherapeutic protocol for first-line treatment of dogs with multicentric intermediate- to large-cell lymphoma

scientific article published on 01 January 2019

Survivin inhibition via EZN-3042 in canine lymphoma and osteosarcoma.

scientific article

The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy

scientific article

The Flint Animal Cancer Center (FACC) Canine Tumour Cell Line Panel: a resource for veterinary drug discovery, comparative oncology and translational medicine.

scientific article published on 19 May 2016

The immunosignature of canine lymphoma: characterization and diagnostic application

scientific article

Tyrosine kinase inhibitor special issue ⬇️

scientific article published on 01 September 2012

Veterinary oncology clinical trials: design and implementation.

scientific article published on 19 December 2014

Vinorelbine rescue therapy for dogs with primary urinary bladder carcinoma.

scientific article published on 25 August 2013

What is your diagnosis? A soft-tissue mass in the thoracic cavity between the heart and the right crus of the diaphragm

scientific article published on 01 January 2000

c-Kit Mutation and Localization Status as Response Predictors in Mast Cell Tumors in Dogs Treated with Prednisone and Toceranib or Vinblastine.

scientific article

c-Met tyrosine kinase receptor expression and function in human and canine osteosarcoma cells

scientific article published on January 1, 2003

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