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List of works by Lynne Murray

Acute cigarette smoke exposure activates apoptotic and inflammatory programs but a second stimulus is required to induce epithelial to mesenchymal transition in COPD epithelium.

scientific article published on 3 May 2017

Antifibrotic role of vascular endothelial growth factor in pulmonary fibrosis.

scientific article

BMP-7 does not protect against bleomycin-induced lung or skin fibrosis

scientific article published in 2008

CXCL11 attenuates bleomycin-induced pulmonary fibrosis via inhibition of vascular remodeling

scientific article published on 22 October 2004

CXCR2 is critical to hyperoxia-induced lung injury.

scientific article

Carboxylic acid bioisosteres acylsulfonamides, acylsulfamides, and sulfonylureas as novel antagonists of the CXCR2 receptor

scientific article published on 7 February 2008

Chemokine (C-C motif) ligand 2 mediates direct and indirect fibrotic responses in human and murine cultured fibrocytes.

scientific article

Circulating monocytes from systemic sclerosis patients with interstitial lung disease show an enhanced profibrotic phenotype.

scientific article

Commonalities between the pro-fibrotic mechanisms in COPD and IPF.

scientific article published on 29 September 2011

Danger-associated molecular patterns and danger signals in idiopathic pulmonary fibrosis.

scientific article published on August 2014

Deleterious role of TLR3 during hyperoxia-induced acute lung injury.

scientific article published on 10 October 2008

Divergent roles for Clusterin in Lung Injury and Repair.

scientific article published on 13 November 2017

Editorial: The Cell Types of Fibrosis

scientific article published in January 2015

Epigenetic mechanisms through which Toll-like receptor-9 drives idiopathic pulmonary fibrosis progression.

scientific article published in July 2012

Generation of bleomycin-induced lung fibrosis is independent of IL-16.

scientific article published on 15 February 2009

Human lung parenchyma but not proximal bronchi produces fibroblasts with enhanced TGF-beta signaling and alpha-SMA expression.

scientific article

Hyper-responsiveness of IPF/UIP fibroblasts: interplay between TGFbeta1, IL-13 and CCL2.

scientific article

Identification of periplakin as a major regulator of lung injury and repair in mice.

scientific article published on 8 March 2018

Increased expression and accumulation of GDF15 in IPF extracellular matrix contribute to fibrosis

scientific article published in 2022

Inhibition of mast cells: a novel mechanism by which nintedanib may elicit anti-fibrotic effects

scientific article published on 24 July 2020

Interstitial lung disease: is interstitial lung disease the same as scleroderma lung disease?

scientific article

Is personalised medicine the key to heterogeneity in idiopathic pulmonary fibrosis?

scientific article published on 6 September 2016

Living with Fibrosis: From Diagnosis to Future Hope.

scientific article

Local apoptosis promotes collagen production by monocyte-derived cells in transforming growth factor β1-induced lung fibrosis ⬇️

scientific article published on May 17, 2011

Long Non-coding RNAs Are Central Regulators of the IL-1β-Induced Inflammatory Response in Normal and Idiopathic Pulmonary Lung Fibroblasts

scientific article published on 11 December 2018

Long-term activation of TLR3 by poly(I:C) induces inflammation and impairs lung function in mice

scientific article published on June 2009

Matrix regulation of idiopathic pulmonary fibrosis: the role of enzymes

scientific article

Origin of myofibroblasts in the fibrotic liver in mice

scientific article

Proteinase-activated receptor-1, CCL2, and CCL7 regulate acute neutrophilic lung inflammation

scientific article published on January 2014

Recombinant protein based therapeutics for IPF.

scientific article published on April 2013

Selective targeting of TGF-β activation to treat fibroinflammatory airway disease

scientific article

Serum amyloid P ameliorates radiation-induced oral mucositis and fibrosis.

scientific article published on 5 July 2010

Serum amyloid P attenuates M2 macrophage activation and protects against fungal spore-induced allergic airway disease

scientific article published on 31 July 2010

Serum amyloid P therapeutically attenuates murine bleomycin-induced pulmonary fibrosis via its effects on macrophages

scientific article (publication date: 12 March 2010)

Smoking and idiopathic pulmonary fibrosis

scientific article published on 19 February 2012

TGF-β-Dependent Dendritic Cell Chemokinesis in Murine Models of Airway Disease.

scientific article published on 24 June 2015

Targeting interleukin-13 with tralokinumab attenuates lung fibrosis and epithelial damage in a humanized SCID idiopathic pulmonary fibrosis model.

scientific article

Targeting of TAM Receptors Ameliorates Fibrotic Mechanisms in Idiopathic Pulmonary Fibrosis.

scientific article published on 10 April 2018

The TGF-β inhibitory activity of antibody 37E1B5 depends on its H-CDR2 glycan.

scientific article published on 11 November 2016

Translational medicine approaches to the study of pulmonary diseases

scientific article published on 01 April 2011

Triggering receptor expressed on myeloid cells-1 (TREM-1) modulates immune responses to Aspergillus fumigatus during fungal asthma in mice.

scientific article

Use of biologics to treat acute exacerbations and manage disease in asthma, COPD and IPF.

scientific article published on 23 November 2016

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