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List of works by Patrick T Harrison

A beginner's guide to gene editing.

scientific article published on 28 December 2017

A convenient method for the construction and expression of GPI-anchored proteins.

scientific article published on September 1994

AAV2-mediated in vivo immune gene therapy of solid tumours

scientific article

Analysis of gene repair tracts from Cas9/gRNA double-stranded breaks in the human CFTR gene.

scientific article published on 25 August 2016

Application of gene therapy in diabetes care.

scientific article published on June 2008

Binding of monomeric immunoglobulin G triggers Fc gamma RI-mediated endocytosis

scientific article (publication date: 30 September 1994)

C-reactive protein-mediated phagocytosis and phospholipase D signalling through the high-affinity receptor for immunoglobulin G (FcgammaRI).

scientific article

Cas9/gRNA targeted excision of cystic fibrosis-causing deep-intronic splicing mutations restores normal splicing of CFTR mRNA.

scientific article published on September 2017

Correction of the ΔF508 Mutation in the Cystic Fibrosis Transmembrane Conductance Regulator Gene by Zinc-Finger Nuclease Homology-Directed Repair

scientific article published on June 2012

Double TALEN-edited T-cells kick B-ALL into touch.

scientific article published in March 2017

E47 retroviral rescue of intrinsic B-cell defects in senescent mice.

scientific article

Effects of GDF5 overexpression on embryonic rat dopaminergic neurones in vitro and in vivo.

scientific article published on 27 March 2010

Evolution of herpesvirus thymidine kinases from cellular deoxycytidine kinase.

scientific article

FcgammaRIIa expression with FcgammaRI results in C-reactive protein- and IgG-mediated phagocytosis.

scientific article published in April 2004

Gene and Base Editing as a Therapeutic Option for Cystic Fibrosis-Learning from Other Diseases

scientific article published on 21 May 2019

Gene editing & stem cells

scientific article

Gene editing and gene regulation with CRISPR.

scientific article published in April 2018

Genetic medicines for CF: Hype versus reality

scientific article published on October 2016

Genetic therapies for cystic fibrosis lung disease.

scientific article published on 3 November 2017

High affinity IgG binding by FcgammaRI (CD64) is modulated by two distinct IgSF domains and the transmembrane domain of the receptor

scientific article published in March 1998

Impact of gene editing on the study of cystic fibrosis

scientific article published on 21 June 2016

Lysosomal routing of Fc gamma RI from early endosomes requires recruitment of tyrosine kinases

scientific article

Neuronal-specific and nerve growth factor-inducible expression directed by the preprotachykinin-A promoter delivered by an adeno-associated virus vector

scientific article

Novel cell lines for the analysis of preprotachykinin A gene expression identify a repressor domain 3' of the major transcriptional start site.

scientific article published on August 1999

Polycystic Kidney Disease Ryanodine Receptor Domain (PKDRR) Proteins in Oomycetes

scientific article published on 16 July 2020

Protein:protein interactions in the lipid bilayer (review).

scientific article published on April 1996

Site-directed mutagenesis of varicella-zoster virus thymidylate synthase. Analysis of two highly conserved regions of the enzyme

scientific article

The Regulation of Monoamine Oxidase A Gene Expression by Distinct Variable Number Tandem Repeats

scientific article published on 14 March 2018

The interaction between human Fc gamma RI and the gamma-chain is mediated solely via the 21 amino acid transmembrane domain of Fc gamma RI.

scientific article

Two distinct regions of FC gamma RI initiate separate signalling pathways involved in endocytosis and phagocytosis

scientific article published on February 1995

Use of GPI‐anchored proteins to study biomolecular interactions by surface plasmon resonance

scientific article published on February 6, 1998

Viral vectors in cancer immunotherapy: which vector for which strategy?

scientific article published on April 2008