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List of works by Martijn C Nawijn

A cellular census of human lungs identifies novel cell states in health and in asthma

scientific article published on 17 June 2019

A specific DAMP profile identifies susceptibility to smoke-induced airway inflammation.

scientific article published on 5 December 2013

Airway epithelial barrier function regulates the pathogenesis of allergic asthma.

scientific article published on January 2014

Alternative Splicing Is a Major Factor Shaping Transcriptome Diversity in Mild and Severe Chronic Obstructive Pulmonary Disease

scientific article published in 2024

An integrated cell atlas of the lung in health and disease

Are allergic multimorbidities and IgE polysensitization associated with the persistence or re-occurrence of foetal type 2 signalling? The MeDALL hypothesis

scientific article published on 24 April 2015

Basophil activation test in mastocytosis patients with and without wasp venom allergy

scientific article published on 28 August 2014

Basophil activation test in the diagnosis and monitoring of mastocytosis patients with wasp venom allergy on immunotherapy

scientific article published on 29 January 2014

Can ACE2 expression explain SARS-CoV-2 infection of the respiratory epithelia in COVID-19?

scientific article published on 01 July 2020

Characterization of a lung epithelium specific E-cadherin knock-out model: Implications for obstructive lung pathology

scientific article published in Scientific Reports

Characterization of protocadherin-1 expression in primary bronchial epithelial cells: association with epithelial cell differentiation

scientific article published on 07 October 2011

Cigarette smoke exposure decreases CFLAR expression in the bronchial epithelium, augmenting susceptibility for lung epithelial cell death and DAMP release

scientific article published in Scientific Reports

Cigarette smoke-induced damage-associated molecular pattern release from necrotic neutrophils triggers proinflammatory mediator release

scientific article published in May 2015

Cigarette smoke-induced necroptosis and DAMP release trigger neutrophilic airway inflammation in mice

scientific article published on 30 December 2015

Comparison of genome-wide gene expression profiling by RNA Sequencing <i>versus</i> microarray in bronchial biopsies of COPD patients before and after inhaled corticosteroid treatment: does it provide new insights?

scientific article published on 15 April 2021

Computational analysis of multimorbidity between asthma, eczema and rhinitis

scientific article

Contribution of regulatory T cells to alleviation of experimental allergic asthma after specific immunotherapy

scientific article published on 01 October 2012

Correction: Susceptibility to chronic mucus hypersecretion, a genome wide association study

scientific article published on 29 May 2015

Cryopreservation does not alter the frequency of regulatory T cells in peripheral blood mononuclear cells

scientific article published on 15 November 2009

Cytotoxic T lymphocyte antigen 4-immunoglobulin G is a potent adjuvant for experimental allergen immunotherapy

scientific article published on 01 April 2013

DAMPs activating innate and adaptive immune responses in COPD.

scientific article published on 23 October 2013

DNA methylation in childhood asthma: an epigenome-wide meta-analysis

scientific article published on 26 February 2018

Decoding asthma: translating genetic variation in IL33 and IL1RL1 into disease pathophysiology.

scientific article published on 04 February 2013

E-cadherin: gatekeeper of airway mucosa and allergic sensitization ⬇️

scientific article published on April 12, 2011

Flow cytometric analysis of cytokine expression in short-term allergen-stimulated T cells mirrors the phenotype of proliferating T cells in long-term cultures

scientific article published on 02 July 2011

For better or for worse: the role of Pim oncogenes in tumorigenesis ⬇️

scientific article published on 09 December 2010

Frat oncoproteins act at the crossroad of canonical and noncanonical Wnt-signaling pathways.

scientific article published on 5 October 2009

GITR signaling potentiates airway hyperresponsiveness by enhancing Th2 cell activity in a mouse model of asthma.

scientific article published on 07 October 2009

Genetic regulation of IL1RL1 methylation and IL1RL1-a protein levels in asthma

scientific article published on 8 March 2018

Genetic variance is associated with susceptibility for cigarette smoke-induced DAMP release in mice

scientific article

Genetic variation associates with susceptibility for cigarette smoke-induced neutrophilia in mice.

scientific article published on 30 January 2015

House dust mite-induced calcium signaling instigates epithelial barrier dysfunction and CCL20 production.

scientific article published on 5 August 2013

Increased neutrophil expression of pattern recognition receptors during COPD exacerbations

scientific article published on 27 September 2016

Increased serum levels of LL37, HMGB1 and S100A9 during exacerbation in COPD patients.

scientific article published in May 2015

Inhibition of Pim1 kinase reduces viral replication in primary bronchial epithelial cells.

scientific article

Inhibition of Pim1 kinase, new therapeutic approach in virus-induced asthma exacerbations.

scientific article

Iron administration reduces airway hyperreactivity and eosinophilia in a mouse model of allergic asthma

scientific article published on 01 October 2011

Mechanisms of the Development of Allergy (MeDALL): Introducing novel concepts in allergy phenotypes

scientific article

Methods for Experimental Allergen Immunotherapy: Subcutaneous and Sublingual Desensitization in Mouse Models of Allergic Asthma

scientific article published on 01 January 2021

Mouse protocadherin-1 gene expression is regulated by cigarette smoke exposure in vivo.

scientific article

Muscarinic receptor subtype-specific effects on cigarette smoke-induced inflammation in mice

scientific article published on 08 February 2013

Paving the way of systems biology and precision medicine in allergic diseases: the MeDALL success story: Mechanisms of the Development of ALLergy; EU FP7-CP-IP; Project No: 261357; 2010-2015.

scientific article

Pim1 kinase activity preserves airway epithelial integrity upon house dust mite exposure

scientific article published on 9 October 2015

Pim1 kinase protects airway epithelial cells from cigarette smoke-induced damage and airway inflammation.

scientific article published on 9 May 2014

Pim3 negatively regulates glucose-stimulated insulin secretion ⬇️

scientific article published on September 1, 2010

Predictive value of serum sST2 in preschool wheezers for development of asthma with high FeNO.

scientific article published on 25 April 2017

Protease-activated receptor-2 activation contributes to house dust mite-induced IgE responses in mice.

scientific article

Protocadherin-1 Localization and Cell-Adhesion Function in Airway Epithelial Cells in Asthma

scientific article

Protocadherin-1 binds to SMAD3 and suppresses TGF-β1-induced gene transcription

scientific article

Protocadherin-1: Epithelial barrier dysfunction in asthma and eczema

scientific article published on 01 March 2014

Recent advances in the epigenetics and genomics of asthma.

scientific article published on October 2011

Serum periostin does not reflect type 2-driven inflammation in COPD.

scientific article

Severe B cell deficiency and disrupted splenic architecture in transgenic mice expressing the E41K mutated form of Bruton's tyrosine kinase ⬇️

scientific article published on September 15, 1998

Shared DNA methylation signatures in childhood allergy: the MeDALL study

scientific article published on 15 December 2020

Smooth-muscle-derived WNT5A augments allergen-induced airway remodelling and Th2 type inflammation

scientific article published on 21 April 2020

Subcutaneous and Sublingual Immunotherapy in a Mouse Model of Allergic Asthma.

scientific article published in January 2017

Subcutaneous immunotherapy suppresses Th2 inflammation and induces neutralizing antibodies, but sublingual immunotherapy suppresses airway hyperresponsiveness in grass pollen mouse models for allergic asthma

scientific article published on 08 June 2018

Subcutaneous immunotherapy with purified Der p1 and 2 suppresses type 2 immunity in a murine asthma model

scientific article published on 10 January 2018

Suppression of Th2-driven airway inflammation by allergen immunotherapy is independent of B cell and Ig responses in mice.

scientific article published on 27 August 2010

Susceptibility for cigarette smoke-induced DAMP release and DAMP-induced inflammation in COPD.

scientific article published on 9 September 2016

Susceptibility to chronic mucus hypersecretion, a genome wide association study

scientific article

TLR-2 activation induces regulatory T cells and long-term suppression of asthma manifestations in mice.

scientific article

The Human Cell Atlas

scientific article

The Human Cell Atlas

The Human Cell Atlas White Paper ⬇️

journal article from 'arXiv:1810.05192 [q-bio]' published in 2018

The Human Lung Cell Atlas: A High-Resolution Reference Map of the Human Lung in Health and Disease

scientific article published on 01 July 2019

The challenge of measuring IL-33 in serum using commercial ELISA: lessons from asthma

scientific article published on 6 February 2016

The discovAIR project: a roadmap towards the Human Lung Cell Atlas

scientific article published on 27 January 2022

The role of the IL-33/IL-1RL1 axis in mast cell and basophil activation in allergic disorders.

scientific article published on 10 July 2014

The single-cell eQTLGen consortium

scientific article published on 09 March 2020

Understanding the complexity of IgE-related phenotypes from childhood to young adulthood: a Mechanisms of the Development of Allergy (MeDALL) seminar

scientific article published on 03 March 2012

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