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List of works by Hideharu Hashimoto

Activity and crystal structure of human thymine DNA glycosylase mutant N140A with 5-carboxylcytosine DNA at low pH

scientific article

Characterization of How DNA Modifications Affect DNA Binding by C2H2 Zinc Finger Proteins.

scientific article published on 16 February 2016

Denys-Drash syndrome associated WT1 glutamine 369 mutants have altered sequence-preferences and altered responses to epigenetic modifications

scientific article

Distinct mechanisms control genome recognition by p53 at its target genes linked to different cell fates

scientific article published on 20 January 2021

Distinctive Klf4 mutants determine preference for DNA methylation status

scientific article

Excision of 5-hydroxymethyluracil and 5-carboxylcytosine by the thymine DNA glycosylase domain: its structural basis and implications for active DNA demethylation ⬇️

scientific article published on September 8, 2012

Excision of thymine and 5-hydroxymethyluracil by the MBD4 DNA glycosylase domain: structural basis and implications for active DNA demethylation

scientific article

Histone H1 null vertebrate cells exhibit altered nucleosome architecture

scientific article

Histone H1 variant, H1R is involved in DNA damage response

scientific article published on 05 July 2007

Human FMRP contains an integral tandem Agenet (Tudor) and KH motif in the amino terminal domain.

scientific article

Independent role for presynaptic FMRP revealed by an FMR1 missense mutation associated with intellectual disability and seizures

scientific journal article

Monoclonal antibody against dnmt1 arrests the cell division of xenopus early-stage embryos.

scientific article published in June 2003

Rad54 is dispensable for the ALT pathway

scientific article published in November 2006

Recognition and potential mechanisms for replication and erasure of cytosine hydroxymethylation ⬇️

scientific article published on February 22, 2012

Selective excision of 5-carboxylcytosine by a thymine DNA glycosylase mutant.

scientific article published on 19 January 2013

Selective non-nucleoside inhibitors of human DNA methyltransferases active in cancer including in cancer stem cells

scientific article published on 15 January 2014

Structural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA.

scientific article published on 15 May 2017

Structural Basis of Protein Arginine Methyltransferase Activation by a Catalytically Dead Homolog (Prozyme)

scientific article published on 11 November 2019

Structural and mutation studies of two DNA demethylation related glycosylases: MBD4 and TDG.

scientific article

Structural basis for Klf4 recognition of methylated DNA

scientific article

Structural basis for human PHF2 Jumonji domain interaction with metal ions

scientific article

Structural basis of specific DNA binding by the transcription factor ZBTB24

scientific article published on 01 September 2019

Structure of Naegleria Tet-like dioxygenase (NgTet1) in complexes with a reaction intermediate 5-hydroxymethylcytosine DNA.

scientific article

Structure of a Naegleria Tet-like dioxygenase in complex with 5-methylcytosine DNA

scientific article

Substrate Affinity and Specificity of the ScSth1p Bromodomain Are Fine-Tuned for Versatile Histone Recognition

scientific article published on 18 July 2019

The Mechanisms of Generation, Recognition, and Erasure of DNA 5-Methylcytosine and Thymine Oxidations

scientific article

The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix

scientific article

The carboxy-terminal domain of ROS1 is essential for 5-methylcytosine DNA glycosylase activity

scientific article

UHRF1, a modular multi-domain protein, regulates replication-coupled crosstalk between DNA methylation and histone modifications

scientific article

Wilms tumor protein recognizes 5-carboxylcytosine within a specific DNA sequence

scientific journal article

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