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List of works by Iain Macphee

A pharmacogenetic strategy for immunosuppression based on the CYP3A5 genotype.

scientific article published in January 2008

A published pharmacogenetic algorithm was poorly predictive of tacrolimus clearance in an independent cohort of renal transplant recipients ⬇️

scientific article published on September 1, 2013

Acute page kidney complicating kidney transplant artery stenting: presentation of a case and novel management

scientific article published in September 2013

BK virus nephropathy in renal transplant patients in London.

scientific article published in April 2008

Biomarkers of Tolerance in Kidney Transplantation: Are We Predicting Tolerance or Response to Immunosuppressive Treatment?

scientific article published on 21 June 2016

Black renal transplant recipients have poorer long-term graft survival than CYP3A5 expressers from other ethnic groups.

scientific article published on 12 October 2009

Blockade of OX40-ligand after initial triggering of the T helper 2 response inhibits mercuric chloride-induced autoimmunity

scientific article published on 01 March 2006

Burkholderia pseudomallei infection, or melioidosis, and nephrotic syndrome

scientific article published on 01 January 2002

CYP3A5 Genotype Had no Impact on Intrapatient Variability of Tacrolimus Clearance in Renal Transplant Recipients ⬇️

scientific article published on June 1, 2013

CYP3A5 genotype does not influence the blood concentration of tacrolimus measured with the Abbott immunoassay.

scientific article published in November 2005

Chapter 3 Demographic and Biochemistry Profile of Kidney Transplant Recipients in the UK in 2010: National and Centre-Specific Analyses ⬇️

scientific article published on January 1, 2012

Compromise of renal transplant blood flow by an arteriovenous graft

scientific article published on 30 March 2006

Does pharmacogenetics have the potential to allow the individualisation of immunosuppressive drug dosing in organ transplantation?

scientific article

Dose-finding study of peginesatide for anemia correction in chronic kidney disease patients

scientific article

Enlarged kidneys and acute renal failure why is a renal biopsy necessary for diagnosis and treatment?

scientific article published on 01 October 2007

Estimated glomerular filtration rate correlates poorly with four-hour creatinine clearance in critically ill patients with acute kidney injury

scientific article published on 5 February 2013

Generic tacrolimus in renal transplantation: trough blood concentration as a surrogate for drug exposure

scientific article published on 01 June 2012

Genotyping cytochrome P450 3A5 using the Light Cycler.

scientific article

Immunosuppression-induced diabetes mellitus

scientific article published on 01 October 2002

Individualized immunosuppression in transplant patients: potential role of pharmacogenetics

scientific article published on 18 June 2012

Long- and short-term outcomes in renal allografts with deceased donors: A large recipient and donor genome-wide association study

scientific article published in February 2018

Multi-drug resistance gene-1 (MDR-1) haplotypes and the CYP3A5*1 genotype have no influence on ciclosporin dose requirements as assessed by C0 or C2 measurements

scientific article published on 01 March 2007

Multidrug resistance gene-1 (MDR-1) haplotypes have a minor influence on tacrolimus dose requirements

scientific article published on 01 September 2006

Page kidney: successful radiological management of acute renal failure

scientific article published on 03 January 2006

Pharmacogenetic biomarkers: cytochrome P450 3A5.

scientific article published on 18 October 2011

Pharmacogenetics as a tool for optimising drug therapy in solid-organ transplantation

scientific article published on September 2007

Pharmacogenetics of immunosuppressive drugs: prospect of individual therapy for transplant patients

scientific article published on May 2008

Polymorphisms in CYP3A5, CYP3A4, and ABCB1 are not associated with cyclosporine pharmacokinetics nor with cyclosporine clinical end points after renal transplantation

scientific article published on 01 April 2011

Proteinuria in 3 sequential pregnancies following a fourth renal transplant

scientific article published on 01 November 2006

Renohepatic crosstalk: does acute kidney injury cause liver dysfunction?

scientific article published on 17 May 2013

Tacrolimus dose in black renal transplant recipients

scientific article published on 01 April 2007

Tacrolimus pharmacogenetics: polymorphisms associated with expression of cytochrome p4503A5 and P-glycoprotein correlate with dose requirement

scientific article

Tacrolimus pharmacogenetics: the CYP3A5*1 allele predicts low dose-normalized tacrolimus blood concentrations in whites and South Asians

scientific article

The effects of acute renal failure on drug metabolism

scientific article published on 28 September 2013

The influence of pharmacogenetics on the time to achieve target tacrolimus concentrations after kidney transplantation.

scientific article

The pharmacogenetics of immunosuppression for organ transplantation: a route to individualization of drug administration.

scientific article published on January 2003

UK Renal Registry 15th annual report: Chapter 3 demographic and biochemistry profile of kidney transplant recipients in the UK in 2011: national and centre-specific analyses

scientific article published on 10 June 2013

Use of pharmacogenetics to optimize immunosuppressive therapy.

scientific article published in June 2010

Using drug probes to monitor hepatic drug metabolism in critically ill patients: midazolam, a flawed but useful tool for clinical investigation of CYP3A activity?

scientific article published on June 2010

Using midazolam to monitor changes in hepatic drug metabolism in critically ill patients.

scientific article published on 7 February 2009

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