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List of works by Nicola J Mutch

A new pedigree with thrombomodulin-associated coagulopathy in which delayed fibrinolysis is partially attenuated by co-inherited TAFI deficiency

scientific article published on 07 July 2020

Activation of single-chain urokinase-type plasminogen activator by platelet-associated plasminogen: a mechanism for stimulation of fibrinolysis by platelets.

scientific article published on 17 February 2010

Altered fibrinolysis in autosomal dominant thrombomodulin-associated coagulopathy.

scientific article published on 19 July 2016

An international study on the feasibility of a standardized combined plasma clot turbidity and lysis assay: communication from the SSC of the ISTH.

scientific article published on 13 March 2018

Defective α2 antiplasmin cross-linking and thrombus stability in a case of acquired factor XIII deficiency

scientific article published on 17 May 2017

Defining trauma-induced coagulopathy with respect to future implications for patient management: Communication from the SSC of the ISTH

scientific article published on 01 March 2020

Emerging roles for factor XII in vivo

scientific article published on 01 July 2011

Endothelial cell oxidative stress in diabetes: a key driver of cardiovascular complications?

scientific article

Evaluation of and recommendation for the nomenclature of the CPB2 gene product (also known as TAFI and proCPU): communication from the SSC of the ISTH.

scientific article

Factor XIIa regulates the structure of the fibrin clot independently of thrombin generation through direct interaction with fibrin

scientific article

Functional factor XIII-A is exposed on the stimulated platelet surface

scientific article

Harmonisation of D-dimer - A call for action

scientific article published on 22 November 2015

Human thrombi contain an abundance of active thrombin

scientific article published on 01 October 2001

Immobilized transition metal ions stimulate contact activation and drive factor XII‐mediated coagulation ⬇️

scientific article published on October 1, 2012

Insights into thrombin activatable fibrinolysis inhibitor function and regulation.

scientific article published on June 2013

Let's cross-link: diverse functions of the promiscuous cellular transglutaminase factor XIII-A

scientific article published on 01 January 2019

Localization and identification of thrombin and plasminogen activator activities in model human thrombi by in situ zymography

scientific article published on 01 December 2002

Model thrombi formed under flow reveal the role of factor XIII-mediated cross-linking in resistance to fibrinolysis

scientific article published on September 2010

Novel aspects of platelet factor XIII function

scientific article published on May 2016

Plasmin and the thrombin-thrombomodulin complex both contribute to thrombin-activatable fibrinolysis inhibitor activation in whole blood model thrombi.

scientific article

Plasminogen activator inhibitor-1 and haemostasis in obesity.

scientific article

Plasminogen associates with phosphatidylserine-exposing platelets and contributes to thrombus lysis under flow

scientific article

Platelet polyphosphates are proinflammatory and procoagulant mediators in vivo

scientific article

Platelet-Mediated Modulation of Fibrinolysis.

scientific article published on 19 February 2017

Polyphosphate as a haemostatic modulator

scientific article published on February 2016

Polyphosphate binds with high affinity to exosite II of thrombin.

scientific article published on 11 December 2009

Polyphosphate colocalizes with factor XII on platelet-bound fibrin and augments its plasminogen activator activity

scientific article

Polyphosphate delays fibrin polymerisation and alters the mechanical properties of the fibrin network ⬇️

scientific article

Polyphosphate modifies the fibrin network and down-regulates fibrinolysis by attenuating binding of tPA and plasminogen to fibrin

scientific article published on 12 March 2010

Polyphosphate modulates blood coagulation and fibrinolysis.

scientific article

Polyphosphate scores a hat trick in regulating host defense mechanisms ⬇️

scientific article published on 01 June 2012

Single-chain factor XII exhibits activity when complexed to polyphosphate

scientific article published on 13 August 2014

The antifibrinolytic function of factor XIII is exclusively expressed through α₂-antiplasmin cross-linking.

scientific article published on 6 April 2011

The use of the Chandler loop to examine the interaction potential of NXY-059 on the thrombolytic properties of rtPA on human thrombi in vitro

scientific article

Theme 1: Pathogenesis of venous thromboembolism (and post-thrombotic syndrome).

scientific article published in September 2015

Thrombin-anti-thrombin levels and patency of arterio-venous fistula in patients undergoing haemodialysis compared to healthy volunteers: a prospective analysis.

scientific article published on 02 July 2013

Thrombus lysis by uPA, scuPA and tPA is regulated by plasma TAFI

scientific article published on 01 September 2003

Time-dependent degradation and tissue factor addition mask the ability of platelet polyphosphates in activating factor XII-mediated coagulation.

scientific article

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