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List of works by Roger W Hunter

Allosteric regulation of glycogen synthase controls glycogen synthesis in muscle

scientific article published on November 3, 2010

Analysis of substrate specificity and cyclin Y binding of PCTAIRE-1 kinase

scientific article

Dual regulation of glycogen synthase kinase 3 (GSK3)α/β by protein kinase C (PKC)α and Akt promotes thrombin-mediated integrin αIIbβ3 activation and granule secretion in platelets.

scientific article published on 13 December 2012

Dysfunction of the PI3 kinase/Rap1/integrin α(IIb)β(3) pathway underlies ex vivo platelet hypoactivity in essential thrombocythemia

scientific article published on 13 December 2012

Expression and purification of functional human glycogen synthase-1:glycogenin-1 complex in insect cells

scientific article

Glucose-6-phosphate-mediated activation of liver glycogen synthase plays a key role in hepatic glycogen synthesis.

scientific article published on 29 August 2013

LKB1 regulates lipid oxidation during exercise independently of AMPK

scientific article published on 24 January 2013

Mechanism of action of compound-13: an α1-selective small molecule activator of AMPK

scientific article

Metformin reduces liver glucose production by inhibition of fructose-1-6-bisphosphatase

scientific article published on 27 August 2018

Molecular mechanism by which AMP-activated protein kinase activation promotes glycogen accumulation in muscle

scientific article published on 31 January 2011

Mutation in the γ2-subunit of AMP-activated protein kinase stimulates cardiomyocyte proliferation and hypertrophy independent of glycogen storage.

scientific article published on 06 February 2014

Protein kinase C and P2Y12 take center stage in thrombin-mediated activation of mammalian target of rapamycin complex 1 in human platelets

scientific article published on May 2014

Protein kinase C-mediated phosphorylation and activation of PDE3A regulate cAMP levels in human platelets.

scientific article published on 4 March 2009

Structural basis for the recruitment of glycogen synthase by glycogenin

scientific article

The Ca(2+) /calmodulin-dependent kinase kinase β-AMP-activated protein kinase-α1 pathway regulates phosphorylation of cytoskeletal targets in thrombin-stimulated human platelets.

scientific article

The PKB inhibitor Akti-1/2 potentiates PAR-1-mediated platelet function independently of its ability to block PKB

scientific article published on 28 August 2008

mTORC2 protein-mediated protein kinase B (Akt) serine 473 phosphorylation is not required for Akt1 activity in human platelets

scientific article published in September 2011