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List of works by Christina Yap

A comparison of short-term and long-term air pollution exposure associations with mortality in two cohorts in Scotland.

scientific article

A multi-centre phase I trial of the PARP inhibitor olaparib in patients with relapsed chronic lymphocytic leukaemia, T-prolymphocytic leukaemia or mantle cell lymphoma

scientific article published on 23 June 2017

A platform incorporating trimeric antigens into self-assembling nanoparticles reveals SARS-CoV-2-spike nanoparticles to elicit substantially higher neutralizing responses than spike alone

scientific article published on 23 October 2020

Acute small bowel toxicity and preoperative chemoradiotherapy for rectal cancer: investigating dose-volume relationships and role for inverse planning.

scientific article published on 31 July 2006

Adaptive designs in clinical trials: why use them, and how to run and report them.

scientific article published on 28 February 2018

Adaptive trial designs: what are multiarm, multistage trials?

scientific article published on 29 October 2019

Adaptive trial designs: what is the continual reassessment method?

scientific article published on 30 October 2019

Association between long-term exposure to air pollution and specific causes of mortality in Scotland

scientific article published on 26 October 2012

Challenges of clinical trial design for targeted agents against pediatric leukemias

scientific article

Combination Lenalidomide and Azacitidine: A Novel Salvage Therapy in Patients Who Relapse After Allogeneic Stem-Cell Transplantation for Acute Myeloid Leukemia

scientific article published on 17 January 2019

Costs and staffing resource requirements for adaptive clinical trials: quantitative and qualitative results from the Costing Adaptive Trials project

scientific article published on 26 October 2021

Designing and evaluating dose-escalation studies made easy: The MoDEsT web app

scientific article published on 19 December 2019

Development of Clinical Criteria for Functional Assessment to Predict Primary Nonfunction of High-Risk Livers Using Normothermic Machine Perfusion

article

Dose Transition Pathways: The Missing Link Between Complex Dose-Finding Designs and Simple Decision-Making

scientific article published on 21 July 2017

Embracing model-based designs for dose-finding trials. ⬇️

scientific article

Evaluation of the mRNA-1273 Vaccine against SARS-CoV-2 in Nonhuman Primates

scientific article published on 28 July 2020

Examining the sources of occupational stress in an emergency department.

scientific article published on 16 November 2016

Granulocyte colony-stimulating factor and autologous CD133-positive stem-cell therapy in liver cirrhosis (REALISTIC): an open-label, randomised, controlled phase 2 trial

scientific article published on 7 November 2017

How to design a dose-finding study using the continual reassessment method

scientific article published on 18 January 2019

Implementing the EffTox dose-finding design in the Matchpoint trial.

scientific article

Newcastle Disease Virus-Like Particles Displaying Prefusion-Stabilized SARS-CoV-2 Spikes Elicit Potent Neutralizing Responses

scientific article

Phase I trial of WEE1 inhibition with chemotherapy and radiotherapy as adjuvant treatment, and a window of opportunity trial with cisplatin in patients with head and neck cancer: the WISTERIA trial protocol

scientific article published on 16 March 2020

REpeated AutoLogous Infusions of STem cells In Cirrhosis (REALISTIC): a multicentre, phase II, open-label, randomised controlled trial of repeated autologous infusions of granulocyte colony-stimulating factor (GCSF) mobilised CD133+ bone marrow stem

scientific article

Ruxolitinib vs best available therapy for ET intolerant or resistant to hydroxycarbamide.

scientific article published on 9 August 2017

Screened selection design for randomised phase II oncology trials: an example in chronic lymphocytic leukaemia

scientific article

Screened selection design for randomised phase II oncology trials: an example in chronic lymphocytic leukaemia

Study protocol for a randomised controlled trial of enhanced informed consent compared to standard informed consent to improve patient understanding of early phase oncology clinical trials (CONSENT)

scientific article published on 06 September 2021

Tolerability and Clinical Activity of Post-Transplantation Azacitidine in Patients Allografted for Acute Myeloid Leukemia Treated on the RICAZA Trial

scientific article published on 9 September 2015

Tolerability of bolus versus continuous gastric feeding in brain-injured patients.

scientific article published in September 2002

Transplantation of discarded livers following viability testing with normothermic machine perfusion

scientific article published on 16 June 2020

Viability testing and transplantation of marginal livers (VITTAL) using normothermic machine perfusion: study protocol for an open-label, non-randomised, prospective, single-arm trial.

scientific article published on 28 November 2017

When to keep it simple - adaptive designs are not always useful

scientific article published on 02 August 2019

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