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List of works by Masanobu Oshima

18β-glycyrrhetinic acid suppresses gastric cancer by activation of miR-149-3p-Wnt-1 signaling.

scientific article published on 04 October 2016

A genome-scale CRISPR screen reveals factors regulating Wnt-dependent renewal of mouse gastric epithelial cells

scientific article published in 2021

A targeted mutation of Nkd1 impairs mouse spermatogenesis.

scientific article

Accelerated onsets of gastric hamartomas and hepatic adenomas/carcinomas in Lkb1+/-p53-/- compound mutant mice

scientific article published on 01 March 2006

Acceleration of intestinal polyposis through prostaglandin receptor EP2 in Apc(Delta 716) knockout mice

scientific journal article

Activation of Bmp2-Smad1 Signal and Its Regulation by Coordinated Alteration of H3K27 Trimethylation in Ras-Induced Senescence ⬇️

scientific article published on November 3, 2011

Adenomatous polyposis coli heterozygous knockout mice display hypoactivity and age-dependent working memory deficits

scientific article

Author Correction: Estrogen-related receptor gamma functions as a tumor suppressor in gastric cancer

scientific article published in Nature Communications

Autophagy regulates levels of tumor suppressor enzyme protein phosphatase 6

scientific article published on 24 September 2020

Blocking TNF-alpha in mice reduces colorectal carcinogenesis associated with chronic colitis

scientific article

CD44 variant regulates redox status in cancer cells by stabilizing the xCT subunit of system xc(-) and thereby promotes tumor growth

scientific article

Canolol inhibits gastric tumors initiation and progression through COX-2/PGE2 pathway in K19-C2mE transgenic mice

scientific article

Cell competition with normal epithelial cells promotes apical extrusion of transformed cells through metabolic changes

scientific article published on 17 April 2017

Chemokine receptor CXCR3 promotes colon cancer metastasis to lymph nodes

scientific article published on 05 February 2007

Claudin-4 deficiency results in urothelial hyperplasia and lethal hydronephrosis.

scientific article

Clinical utility of a STAT3-regulated microRNA-200 family signature with prognostic potential in early gastric cancer.

scientific article published on 12 January 2018

Context-dependent activation of Wnt signaling by tumor suppressor RUNX3 in gastric cancer cells

scientific article

Cyclooxygenase 2- and prostaglandin E(2) receptor EP(2)-dependent angiogenesis in Apc(Delta716) mouse intestinal polyps

scientific journal article

Early embryonic lethality caused by targeted disruption of the mouse selenocysteine tRNA gene (Trsp).

scientific article

Estrogen-induced tumorigenesis in the pituitary gland of TGF-beta(+/-) knockout mice.

scientific article published in July 1998

Estrogen-related receptor gamma functions as a tumor suppressor in gastric cancer.

scientific article published on 15 May 2018

Gut Microbiota Promotes Obesity-Associated Liver Cancer through PGE2-Mediated Suppression of Antitumor Immunity

scientific article published on 15 February 2017

HMGA1 is induced by Wnt/beta-catenin pathway and maintains cell proliferation in gastric cancer

scientific article published on 03 September 2009

Hepatocellular carcinoma development induced by conditional beta-catenin activation in Lkb1+/- mice.

scientific article

Identification of a TLR2-regulated gene signature associated with tumor cell growth in gastric cancer.

scientific article

Identification of tumor-initiating cells in a highly aggressive brain tumor using promoter activity of nucleostemin.

scientific article published on 17 September 2009

Impact of inflammation-metaplasia-adenocarcinoma sequence and inflammatory microenvironment in esophageal carcinogenesis using surgical rat models

scientific article published on 14 February 2014

Inflammation in gastric cancer: Interplay of the COX-2/prostaglandin E2 and Toll-like receptor/MyD88 pathways

scientific article

Inflammatory and mitogenic signals drive interleukin 23 subunit alpha (IL23A) secretion independent of IL12B in intestinal epithelial cells

scientific article published on 24 March 2020

Inhibition of β-catenin and STAT3 with a curcumin analog suppresses gastric carcinogenesis in vivo

scientific article

Interleukin-11-expressing fibroblasts have a unique gene signature correlated with poor prognosis of colorectal cancer

scientific article published on 16 April 2021

Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes

scientific journal article

Laser Microdissection of Cellular Compartments for Expression Analyses in Cancer Models.

scientific article published in January 2018

Loss of wild-type p53 promotes mutant p53-driven metastasis through acquisition of survival and tumor-initiating properties

scientific article published on 11 May 2020

Malignant subclone drives metastasis of genetically and phenotypically heterogenous cell clusters through fibrotic niche generation

scientific article published in 2021

Matrix metalloproteinase 7 is required for tumor formation, but dispensable for invasion and fibrosis in SMAD4-deficient intestinal adenocarcinomas

scientific article published on 10 November 2008

Mouse gastric tumor models with prostaglandin E2 pathway activation show similar gene expression profiles to intestinal-type human gastric cancer

scientific article

Mutant p53 in colon cancer

scientific article published on 01 April 2019

NF-κB-induced NOX1 activation promotes gastric tumorigenesis through the expansion of SOX2-positive epithelial cells

scientific article published on 30 January 2019

NOTUM is a potential pharmacodynamic biomarker of Wnt pathway inhibition.

scientific article published on 03 February 2016

Nardilysin regulates inflammation, metaplasia, and tumors in murine stomach

scientific article

Nuclear translocation of beta-catenin in hereditary and carcinogen-induced intestinal adenomas.

scientific article published on April 1998

Requisite role of vasohibin-2 in spontaneous gastric cancer formation and accumulation of cancer-associated fibroblasts

scientific article published on 27 September 2017

Roles of cyclooxygenase-2 and microsomal prostaglandin E synthase-1 expression and beta-catenin activation in gastric carcinogenesis in N-methyl-N-nitrosourea-treated K19-C2mE transgenic mice.

scientific article published on 17 November 2008

SMAD4-deficient intestinal tumors recruit CCR1+ myeloid cells that promote invasion

scientific article published on 18 March 2007

Suppression of tubulin polymerization by the LKB1-microtubule-associated protein/microtubule affinity-regulating kinase signaling

scientific article published on 15 June 2007

Targeted disruption of the mouse rho-associated kinase 2 gene results in intrauterine growth retardation and fetal death

scientific article

The threshold level of adenomatous polyposis coli protein for mouse intestinal tumorigenesis.

scientific article

Therapeutic activity of glycoengineered anti-GM2 antibodies against malignant pleural mesothelioma.

scientific article

Toll-like receptor 2: therapeutic target for gastric carcinogenesis.

scientific article published in November 2012

Validation of MIMGO: a method to identify differentially expressed GO terms in a microarray dataset ⬇️

scientific article published on December 12, 2012

[COX inhibitor, suppression of polyposis, and chemoprevention].

scientific article published in November 2002

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