List of works - Laurent O Martinez

A PEST sequence in ABCA1 regulates degradation by calpain protease and stabilization of ABCA1 by apoA-I.

scientific article

A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice

scientific article published on 28 November 2016

Apolipoprotein A-I enhances proliferation of human endothelial progenitor cells and promotes angiogenesis through the cell surface ATP synthase

scientific article published on 8 November 2014

Association of hepatic lipase -514T allele with coronary artery disease and ankle-brachial index, dependence on the lipoprotein phenotype: the GENES study

scientific article published on 9 July 2013

Cell surface adenylate kinase activity regulates the F(1)-ATPase/P2Y (13)-mediated HDL endocytosis pathway on human hepatocytes.

scientific article published on December 2006

Characterization of immortalized human dermal microvascular endothelial cells (HMEC-1) for the study of HDL functionality

scientific article published on 9 March 2018

Chronic pharmacological activation of P2Y13 receptor in mice decreases HDL-cholesterol level by increasing hepatic HDL uptake and bile acid secretion

scientific article published on 20 December 2012

Common p2y13 polymorphisms are associated with plasma inhibitory factor 1 and lipoprotein(a) concentrations, heart rate and body fat mass: The GENES study

scientific article published on 29 December 2018

Deciphering biased inverse agonism of cangrelor and ticagrelor at P2Y receptor

article

Ecto-F1-ATPase and MHC-class I close association on cell membranes

scientific article

Ecto-F1-ATPase/P2Y pathways in metabolic and vascular functions of high density lipoproteins.

scientific article

Ectopic adenine nucleotide translocase activity controls extracellular ADP levels and regulates the F1-ATPase-mediated HDL endocytosis pathway on hepatocytes.

scientific article published on 11 May 2017

Elastin-derived peptides potentiate atherosclerosis through the immune Neu1-PI3Kγ pathway.

scientific article

Identification of the F1-ATPase at the cell surface of colonic epithelial cells: role in mediating cell proliferation.

scientific article published on 10 October 2012

Increased atherosclerosis in P2Y13/apolipoprotein E double-knockout mice: contribution of P2Y13 to reverse cholesterol transport

scientific article published on 13 March 2015

Lack of P2Y13 in mice fed a high cholesterol diet results in decreased hepatic cholesterol content, biliary lipid secretion and reverse cholesterol transport

scientific article

Liraglutide improves hepatic steatosis and metabolic dysfunctions in a 3-week dietary mouse model of nonalcoholic steatohepatitis

scientific article published on 28 August 2019

PI3Kβ Plays a Key Role in Apolipoprotein A-I-Induced Endothelial Cell Proliferation Through Activation of the Ecto-F1-ATPase/P2Y1 Receptors

scientific article published on 05 June 2017

Paclitaxel induces lymphatic endothelial cells autophagy to promote metastasis

scientific article published on 20 December 2019

Pharmacological inhibition of the F1 -ATPase/P2Y1 pathway suppresses the effect of apolipoprotein A1 on endothelial nitric oxide synthesis and vasorelaxation

scientific article published on 04 April 2019

Phosphorylation of a pest sequence in ABCA1 promotes calpain degradation and is reversed by ApoA-I

scientific journal article

Prediction of coronary heart disease incidence in a general male population by circulating non-coding small RNA sRNY1-5p in a nested case-control study

scientific article published on 19 January 2021

RNY-derived small RNAs as a signature of coronary artery disease

scientific article

Role of apolipoproteins in gammadelta and NKT cell-mediated innate immunity.

scientific article

Role of the ubiquitin-proteasome system in the regulation of P2Y13 receptor expression: impact on hepatic HDL uptake

scientific article published on 13 September 2013

Serum IF1 concentration is independently associated to HDL levels and to coronary heart disease: the GENES study.

scientific article published on 21 June 2013

Serum inhibitory factor 1, high-density lipoprotein and cardiovascular diseases.

scientific article

Serum level of HDL particles are independently associated with long-term prognosis in patients with coronary artery disease: The GENES study

scientific article published on 18 May 2020

Serum levels of mitochondrial inhibitory factor 1 are independently associated with long-term prognosis in coronary artery disease: the GENES Study ⬇️

scientific article

Short-term cooling increases serum triglycerides and small high-density lipoprotein levels in humans.

scientific article published on 3 May 2017

Specific requirements for Vgamma9Vdelta2 T cell stimulation by a natural adenylated phosphoantigen.

scientific article

Stimulation of cell surface F1-ATPase activity by apolipoprotein A-I inhibits endothelial cell apoptosis and promotes proliferation.

scientific article published on 16 April 2009

Targeting PI3Kγ activity decreases vascular trauma-induced intimal hyperplasia through modulation of the Th1 response.

scientific article

Targeting high-density lipoproteins: update on a promising therapy.

scientific article published on 25 September 2013

The nucleotide receptor P2Y13 is a key regulator of hepatic high-density lipoprotein (HDL) endocytosis.

scientific article published in November 2005

Treatment with PCSK9 inhibitors induces a more anti-atherogenic HDL lipid profile in patients at high cardiovascular risk

scientific article published on 25 September 2020

Tumor recognition following Vgamma9Vdelta2 T cell receptor interactions with a surface F1-ATPase-related structure and apolipoprotein A-I

scientific article published on 01 January 2005

List of works by Laurent O Martinez

A PEST sequence in ABCA1 regulates degradation by calpain protease and stabilization of ABCA1 by apoA-I.

A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice

Apolipoprotein A-I enhances proliferation of human endothelial progenitor cells and promotes angiogenesis through the cell surface ATP synthase

Association of hepatic lipase -514T allele with coronary artery disease and ankle-brachial index, dependence on the lipoprotein phenotype: the GENES study

Cell surface adenylate kinase activity regulates the F(1)-ATPase/P2Y (13)-mediated HDL endocytosis pathway on human hepatocytes.

Characterization of immortalized human dermal microvascular endothelial cells (HMEC-1) for the study of HDL functionality

Chronic pharmacological activation of P2Y13 receptor in mice decreases HDL-cholesterol level by increasing hepatic HDL uptake and bile acid secretion

Common p2y13 polymorphisms are associated with plasma inhibitory factor 1 and lipoprotein(a) concentrations, heart rate and body fat mass: The GENES study

Deciphering biased inverse agonism of cangrelor and ticagrelor at P2Y receptor

Ecto-F1-ATPase and MHC-class I close association on cell membranes

Ecto-F1-ATPase/P2Y pathways in metabolic and vascular functions of high density lipoproteins.

Ectopic adenine nucleotide translocase activity controls extracellular ADP levels and regulates the F1-ATPase-mediated HDL endocytosis pathway on hepatocytes.

Elastin-derived peptides potentiate atherosclerosis through the immune Neu1-PI3Kγ pathway.

Identification of the F1-ATPase at the cell surface of colonic epithelial cells: role in mediating cell proliferation.

Increased atherosclerosis in P2Y13/apolipoprotein E double-knockout mice: contribution of P2Y13 to reverse cholesterol transport

Lack of P2Y13 in mice fed a high cholesterol diet results in decreased hepatic cholesterol content, biliary lipid secretion and reverse cholesterol transport

Liraglutide improves hepatic steatosis and metabolic dysfunctions in a 3-week dietary mouse model of nonalcoholic steatohepatitis

PI3Kβ Plays a Key Role in Apolipoprotein A-I-Induced Endothelial Cell Proliferation Through Activation of the Ecto-F1-ATPase/P2Y1 Receptors

Paclitaxel induces lymphatic endothelial cells autophagy to promote metastasis

Pharmacological inhibition of the F1 -ATPase/P2Y1 pathway suppresses the effect of apolipoprotein A1 on endothelial nitric oxide synthesis and vasorelaxation

Phosphorylation of a pest sequence in ABCA1 promotes calpain degradation and is reversed by ApoA-I

Prediction of coronary heart disease incidence in a general male population by circulating non-coding small RNA sRNY1-5p in a nested case-control study

RNY-derived small RNAs as a signature of coronary artery disease

Role of apolipoproteins in gammadelta and NKT cell-mediated innate immunity.

Role of the ubiquitin-proteasome system in the regulation of P2Y13 receptor expression: impact on hepatic HDL uptake

Serum IF1 concentration is independently associated to HDL levels and to coronary heart disease: the GENES study.

Serum inhibitory factor 1, high-density lipoprotein and cardiovascular diseases.

Serum level of HDL particles are independently associated with long-term prognosis in patients with coronary artery disease: The GENES study

Serum levels of mitochondrial inhibitory factor 1 are independently associated with long-term prognosis in coronary artery disease: the GENES Study ⬇️

Short-term cooling increases serum triglycerides and small high-density lipoprotein levels in humans.

Specific requirements for Vgamma9Vdelta2 T cell stimulation by a natural adenylated phosphoantigen.

Stimulation of cell surface F1-ATPase activity by apolipoprotein A-I inhibits endothelial cell apoptosis and promotes proliferation.

Targeting PI3Kγ activity decreases vascular trauma-induced intimal hyperplasia through modulation of the Th1 response.

Targeting high-density lipoproteins: update on a promising therapy.

The nucleotide receptor P2Y13 is a key regulator of hepatic high-density lipoprotein (HDL) endocytosis.

Treatment with PCSK9 inhibitors induces a more anti-atherogenic HDL lipid profile in patients at high cardiovascular risk

Tumor recognition following Vgamma9Vdelta2 T cell receptor interactions with a surface F1-ATPase-related structure and apolipoprotein A-I