Search filters

Authors whose works are in public domain in at least one jurisdiction

List of works by Hyuk Wan Ko

A hierarchical phosphorylation cascade that regulates the timing of PERIOD nuclear entry reveals novel roles for proline-directed kinases and GSK-3beta/SGG in circadian clocks.

scientific article

An inactivating mutation in intestinal cell kinase, ICK, impairs hedgehog signalling and causes short rib-polydactyly syndrome.

scientific article published on 27 July 2016

Broad-minded links cell cycle-related kinase to cilia assembly and hedgehog signal transduction

scientific journal article

Capsaicin prevents degeneration of dopamine neurons by inhibiting glial activation and oxidative stress in the MPTP model of Parkinson's disease

scientific article

Cell Cycle-Related Kinase (CCRK) regulates ciliogenesis and Hedgehog signaling in mice

scientific article

Ciliary smoothened-mediated noncanonical hedgehog signaling promotes tubulin acetylation.

scientific article published on 25 October 2016

Design, synthesis, and biological evaluation of structurally modified isoindolinone and quinazolinone derivatives as hedgehog pathway inhibitors

scientific article

Drosophila peptidyl-prolyl isomerase Pin1 modulates circadian rhythms via regulating levels of PERIOD.

scientific article published on 18 May 2015

Effects of substrate conductivity on cell morphogenesis and proliferation using tailored, atomic layer deposition-grown ZnO thin films

scientific article published on 21 April 2015

Fibroblast growth factor receptor influences primary cilium length through an interaction with intestinal cell kinase

scientific article published on 19 February 2019

Fluoxetine prevents MPTP-induced loss of dopaminergic neurons by inhibiting microglial activation.

scientific article published in February 2011

Injury-stimulated Sonic hedgehog expression in microglia contributes to neuroinflammatory response in the MPTP model of Parkinson's disease.

scientific article published on 26 November 2016

Intestinal cell kinase, a protein associated with endocrine-cerebro-osteodysplasia syndrome, is a key regulator of cilia length and Hedgehog signaling

scientific journal article

Intraflagellar transport protein 122 antagonizes Sonic Hedgehog signaling and controls ciliary localization of pathway components ⬇️

scientific article published on January 5, 2011

Leptin Elongates Hypothalamic Neuronal Cilia via Transcriptional Regulation and Actin Destabilization

scientific article published on 3 June 2015

Leptin-promoted cilia assembly is critical for normal energy balance

scientific article published on 25 March 2014

Localization of primary cilia in mouse retina.

scientific article published on 19 April 2013

Mangosteen Extract Prevents Dextran Sulfate Sodium-Induced Colitis in Mice by Suppressing NF-κB Activation and Inflammation.

scientific article published on 27 June 2017

NEMO/NLK Phosphorylates PERIOD to Initiate a Time-Delay Phosphorylation Circuit that Sets Circadian Clock Speed ⬇️

scientific article published on April 29, 2011

NT-4/5 exacerbates free radical-induced neuronal necrosis in vitro and in vivo

scientific article published on 01 August 2000

Natural variation in the splice site strength of a clock gene and species-specific thermal adaptation.

scientific article published on December 2008

Nuclear factor kappa B-mediated kainate neurotoxicity in the rat and hamster hippocampus

scientific article published on 01 January 1999

PEGylated hyaluronic acid-coated liposome for enhanced in vivo efficacy of sorafenib via active tumor cell targeting and prolonged systemic exposure

scientific article published on 14 December 2017

Paclitaxel-Nanodiamond Nanocomplexes Enhance Aqueous Dispersibility and Drug Retention in Cells

scientific article published on 22 August 2016

Pax3 function is required specifically for inner ear structures with melanogenic fates.

scientific article published on 21 February 2014

Primary cilia in energy balance signaling and metabolic disorder

scientific article published on 5 November 2015

Role for Slimb in the degradation of Drosophila Period protein phosphorylated by Doubletime.

scientific article published on 20 November 2002

Single-stranded DNA aptamer that specifically binds to the influenza virus NS1 protein suppresses interferon antagonism.

scientific article published on 19 September 2013

Sulforaphene Interferes with Human Breast Cancer Cell Migration and Invasion through Inhibition of Hedgehog Signaling.

scientific article published on 21 June 2016

Synergetic activation of p38 mitogen-activated protein kinase and caspase-3-like proteases for execution of calyculin A-induced apoptosis but not N-methyl-d-aspartate-induced necrosis in mouse cortical neurons

scientific article published on 01 June 2000

The cDNA cloning and ontogeny of mouse α-synuclein ⬇️

scientific article published on April 20, 1998

Two distinct modes of PERIOD recruitment onto dCLOCK reveal a novel role for TIMELESS in circadian transcription.

scientific article

Vaccinia-related kinase 3 (VRK3) sets the circadian period and amplitude by affecting the subcellular localization of clock proteins in mammalian cells.

scientific article published on 12 April 2017

α-Mangostin ameliorates dextran sulfate sodium-induced colitis through inhibition of NF-κB and MAPK pathways.

scientific article published on 7 June 2017

Paulina is supported by:

About Paulina

Help