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List of works by Kelvin H. Lee

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The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line

scientific article
Shotgun proteomics using the iTRAQ isobaric tags

scientific article published on 10 May 2006
8-plex quantitation of changes in cerebrospinal fluid protein expression in subjects undergoing intravenous immunoglobulin treatment for Alzheimer's disease

scientific article
Totally asymmetric exclusion process with extended objects: A model for protein synthesis

scientific article published on August 18, 2003
Cerebrospinal fluid proteomic biomarkers for Alzheimer's disease

scientific article published in February 2007
Identification and characterization of host cell protein product-associated impurities in monoclonal antibody bioprocessing

scientific article published on 11 December 2013
Insights into the relation between mRNA and protein expression patterns: I. Theoretical considerations

scientific article published in December 2003
A comparison of the consistency of proteome quantitation using two-dimensional electrophoresis and shotgun isobaric tagging in Escherichia coli cells

scientific article published in June 2005
Studies of potential cerebrospinal fluid molecular markers for Alzheimer's disease

scientific article (publication date: July 2002)
Quantitative analysis of protein expression using amine-specific isobaric tags in Escherichia coli cells expressing rhsA elements

scientific article
Insights into the relation between mrna and protein expression patterns: II. Experimental observations in Escherichia coli

scientific article
Chinese hamster genome database: an online resource for the CHO community at www.CHOgenome.org

scientific article
Expression of difficult-to-remove host cell protein impurities during extended Chinese hamster ovary cell culture and their impact on continuous bioprocessing

scientific article published on 16 January 2015
Inverse metabolic engineering: a strategy for directed genetic engineering of useful phenotypes

scientific article published in September 2002
Complement protein isoforms in CSF as possible biomarkers for neurodegenerative disease

scientific article published on January 2005
Proteomic assessment of a cell model of spinal muscular atrophy

scientific article
Apolipoprotein E and other cerebrospinal fluid proteins differentiate ante mortem variant Creutzfeldt-Jakob disease from ante mortem sporadic Creutzfeldt-Jakob disease

scientific article published in July 2002
Membrane configuration optimization for a murine in vitro blood–brain barrier model

scientific article published on November 3, 2012
Murine in vitro model of the blood-brain barrier for evaluating drug transport

scientific article
Functional genomics and proteomics as a foundation for systems biology

scientific article published in October 2003
A two-dimensional electrophoresis map of Chinese hamster ovary cell proteins based on fluorescence staining

scientific article published in August 2004
Genomics in mammalian cell culture bioprocessing

scientific article published on November 4, 2011
Genomic sequencing and analysis of a Chinese hamster ovary cell line using Illumina sequencing technology

scientific article
Knockout of a difficult-to-remove CHO host cell protein, lipoprotein lipase, for improved polysorbate stability in monoclonal antibody formulations

scientific article published on 12 December 2016
Quantitative and qualitative measure of intralaboratory two-dimensional protein gel reproducibility and the effects of sample preparation, sample load, and image analysis

scientific article published in October 2003
Towards two-dimensional electrophoresis mapping of the cerebrospinal fluid proteome from a single individual

scientific article published in August 2004
Escherichia coli--a model system that benefits from and contributes to the evolution of proteomics

scientific article published in December 2003
Proteomic analysis of cerebrospinal fluid changes related to postmortem interval

scientific article published on 3 August 2006
Recovery of Chinese hamster ovary host cell proteins for proteomic analysis

scientific article published on 10 December 2013
Serine phosphorylation is critical for the activation of ubiquitin-specific protease 1 and its interaction with WD40-repeat protein UAF1.

scientific article published on November 2012
iTRAQPak: an R based analysis and visualization package for 8-plex isobaric protein expression data

scientific article
Kinetic characterization of sequencing grade modified trypsin

scientific article published in June 2005
Comparison of automated in-gel digest methods for femtomole level samples

scientific article
Targeted human cerebrospinal fluid proteomics for the validation of multiple Alzheimer's disease biomarker candidates

scientific article published on 10 May 2013
Cytochalasin D can improve heterologous protein productivity in adherent Chinese hamster ovary cells

scientific article published in May 2005
Minimum Transendothelial Electrical Resistance Thresholds for the Study of Small and Large Molecule Drug Transport in a Human in Vitro Blood-Brain Barrier Model

scientific article published on 15 November 2016
Profiling conserved microRNA expression in recombinant CHO cell lines using Illumina sequencing.

scientific article published on 23 January 2012
Recent cerebrospinal fluid biomarker studies of Alzheimer's disease

scientific article
An introduction to mass spectrometry applications in biological research

scientific article published on March 1, 2004
CHOgenome.org 2.0: Genome resources and website updates.

scientific article published on 28 April 2015
Host cell protein impurities in chromatographic polishing steps for monoclonal antibody purification

scientific article published on 9 November 2015
A comparison of three commercially available isoelectric focusing units for proteome analysis: the multiphor, the IPGphor and the protean IEF cell

scientific article published on 01 March 2000
Effects of copper on CHO cells: Insights from gene expression analyses

scientific article published on January 21, 2014
Engineering HlyA hypersecretion in Escherichia coli based on proteomic and microarray analyses

scientific article published in January 2005
Longitudinal analysis of novel Alzheimer's disease proteomic cerebrospinal fluid biomarkers during intravenous immunoglobulin therapy

scientific article
Overexpression of cloned RhsA sequences perturbs the cellular translational machinery in Escherichia coli

scientific article
A reference genome of the Chinese hamster based on a hybrid assembly strategy

article
Optimization of protein sample preparation for two-dimensional electrophoresis

scientific article published in July 2012
Complex and extensive post-transcriptional regulation revealed by integrative proteomic and transcriptomic analysis of metabolite stress response in Clostridium acetobutylicum

scientific article
Optimization of endothelial cell growth in a murine in vitro blood–brain barrier model

scientific article published on December 28, 2011

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