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List of works by Ioannis Zaganas

A case of human immunodeficiency virus infection disclosed by cytomegalovirus encephalitis.

scientific article published on 28 February 2007

A comparison of acute hemorrhagic stroke outcomes in 2 populations: the Crete-Boston study

scientific article published on 20 October 2011

A neurologist with a lifetime fascination for neurochemistry: preface for the special issue dedicated to Dr. Andreas Plaitakis. Preface

scientific article published on 7 December 2013

A8344G tRNALys mutation associated with recurrent brain stem stroke-like episodes

scientific article published on 27 February 2009

Age-related decline in verbal learning is moderated by demographic factors, working memory capacity, and presence of amnestic mild cognitive impairment

scientific article published on 26 August 2014

Anti-CV2 associated cerebellar degeneration after complete response to chemoradiation of head and neck carcinoma

scientific article published on 02 October 2009

Apolipoprotein E ɛ4 (APOE ɛ4) Allele is Associated with Long Sleep Duration Among Elderly with Cognitive Impairment

scientific article published on 19 December 2020

Associations between sleep duration and cognitive impairment in mild cognitive impairment

scientific article published on 21 April 2019

Cerebrospinal Fluid TAR DNA-Binding Protein 43 Combined with Tau Proteins as a Candidate Biomarker for Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Spectrum Disorders.

scientific article published on 23 August 2017

Cerebrovascular events in inflammatory bowel disease patients treated with anti-tumour necrosis factor alpha agents

scientific article

Cognitive Impairment and Dementia in Primary Care: Current Knowledge and Future Directions Based on Findings From a Large Cross-Sectional Study in Crete, Greece

scientific article published on 23 November 2020

Cognitive impairment in a primary healthcare population: a cross-sectional study on the island of Crete, Greece

scientific article published on 24 September 2020

Cognitive screening tools for primary care settings: examining the 'Test Your Memory' and 'General Practitioner assessment of Cognition' tools in a rural aging population in Greece.

scientific article published in December 2017

Cultural adaptation, standardization and clinical validity of the test your memory dementia screening instrument in Greek.

scientific article published on 24 October 2013

Deregulation of glutamate dehydrogenase in human neurologic disorders.

scientific article published on 06 March 2013

Differential interaction of hGDH1 and hGDH2 with manganese: Implications for metabolism and toxicity

scientific article published on 30 March 2015

Estrogen modification of human glutamate dehydrogenases is linked to enzyme activation state.

scientific article

Expression of human GLUD2 glutamate dehydrogenase in human tissues: functional implications.

scientific article

Expression of the human isoform of glutamate dehydrogenase, hGDH2, augments TCA cycle capacity and oxidative metabolism of glutamate during glucose deprivation in astrocytes

scientific article

Gain-of-function variant in GLUD2 glutamate dehydrogenase modifies Parkinson's disease onset

scientific article

Genetic cause of heterogeneous inherited myopathies in a cohort of Greek patients

scientific article published on 30 November 2020

Glutamate dehydrogenase isoforms with N-terminal (His)6- or FLAG-tag retain their kinetic properties and cellular localization.

scientific article published on 26 April 2013

Human GLUD1 and GLUD2 glutamate dehydrogenase localize to mitochondria and endoplasmic reticulum.

scientific article

Human GLUD2 glutamate dehydrogenase is expressed in neural and testicular supporting cells

scientific article

Import of a major mitochondrial enzyme depends on synergy between two distinct helices of its presequence.

scientific article published on 15 July 2016

Interaction between glutamate dehydrogenase (GDH) and L-leucine catabolic enzymes: intersecting metabolic pathways

scientific article published on 20 May 2011

Linking pesticide exposure and dementia: what is the evidence?

scientific article published on 14 February 2013

Localization of Human Glutamate Dehydrogenases Provides Insights into Their Metabolic Role and Their Involvement in Disease Processes

scientific article published on 25 June 2018

Molecular basis of human glutamate dehydrogenase regulation under changing energy demands

scientific article

Mutations in human GLUD2 glutamate dehydrogenase affecting basal activity and regulation.

scientific article

Myelin content changes in probable Alzheimer's disease and mild cognitive impairment: Associations with age and severity of neuropsychiatric impairment.

scientific article

Objective Daytime Napping is Associated with Disease Severity and Inflammation in Patients with Mild to Moderate Dementia1

scientific article published on 26 February 2020

Peptide EphB2/CTF2 generated by the gamma-secretase processing of EphB2 receptor promotes tyrosine phosphorylation and cell surface localization of N-methyl-D-aspartate receptors.

scientific article published on 06 August 2009

Pilomotor seizures: an unusual presentation of limbic encephalitis

scientific article published on 07 October 2015

Regulation of human glutamate dehydrogenases: implications for glutamate, ammonia and energy metabolism in brain.

scientific article

Side-chain interactions in the regulatory domain of human glutamate dehydrogenase determine basal activity and regulation.

scientific article published on 26 January 2015

Single amino acid substitution (G456A) in the vicinity of the GTP binding domain of human housekeeping glutamate dehydrogenase markedly attenuates GTP inhibition and abolishes the cooperative behavior of the enzyme.

scientific article

Study of structure-function relationships in human glutamate dehydrogenases reveals novel molecular mechanisms for the regulation of the nerve tissue-specific (GLUD2) isoenzyme

scientific article

Substitution of Ser for Arg-443 in the regulatory domain of human housekeeping (GLUD1) glutamate dehydrogenase virtually abolishes basal activity and markedly alters the activation of the enzyme by ADP and L-leucine.

scientific article published on 24 September 2002

Temporal trends and associated factors for pre-hospital and in-hospital delays of stroke patients over a 16-year period: the Athens study.

scientific article published on 21 December 2010

The Cretan Aging Cohort: Cohort Description and Burden of Dementia and Mild Cognitive Impairment

scientific article published on 27 September 2018

The Glutamate Dehydrogenase Pathway and Its Roles in Cell and Tissue Biology in Health and Disease

scientific article published on 08 February 2017

The complex regulation of human glud1 and glud2 glutamate dehydrogenases and its implications in nerve tissue biology

scientific article

The effect of pH and ADP on ammonia affinity for human glutamate dehydrogenases.

scientific article published on 20 February 2013

The human GLUD2 glutamate dehydrogenase: localization and functional aspects

scientific article

The impact of mild cognitive impairment on the self-regulation process: A comparison study of persons with mild cognitive impairment and cognitively healthy older adults

scientific article published on 24 October 2016

The odyssey of a young gene: structure-function studies in human glutamate dehydrogenases reveal evolutionary-acquired complex allosteric regulation mechanisms.

scientific article published on 11 February 2014

Transgenic Mice Carrying GLUD2 as a Tool for Studying the Expressional and the Functional Adaptation of this Positive Selected Gene in Human Brain Evolution

scientific article published on 18 May 2018

Whole exome sequencing establishes diagnosis of Charcot-Marie-Tooth 4J, 1C, and X1 subtypes

scientific article published on 05 February 2020

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