List of works - Marc C Devocelle

A Theoretical Analysis of the Prodrug Delivery System for Treating Antibiotic-Resistant Bacteria

scientific article published on 01 May 2011

A computational model of antibiotic-resistance mechanisms in methicillin-resistant Staphylococcus aureus (MRSA).

scientific article published on 4 June 2008

A convenient parallel synthesis of low molecular weight hydroxamic acids using polymer-supported 1-hydroxybenzotriazole.

scientific article published in March 2003

A novel family of hydroxamate-based acylating inhibitors of cyclooxygenase

scientific article (publication date: February 2003)

A novel role for the fibrinogen Asn-Gly-Arg (NGR) motif in platelet function.

scientific article published on 20 November 2014

A peptide affinity column for the identification of integrin alpha IIb-binding proteins

scientific article

AMP kinase-mediated activation of the BH3-only protein Bim couples energy depletion to stress-induced apoptosis

scientific article

Absolute Net Charge and the Biological Activity of Oligopeptides

scientific article published on 01 September 2006

Action of antimicrobial peptides and their prodrugs on model and biological membranes

scientific article published on 24 May 2018

Assessing the correlation of microscopy-based and volumetry-based measurements for resin swelling in a range of potential greener solvents for SPPS

scientific article published on 25 March 2020

Benzyl N-[2-(1H-indol-3-yl)eth-yl]dithio-carbamate.

scientific article published on 18 December 2007

Biosynthesis of 2-aminooctanoic acid and its use to terminally modify a lactoferricin B peptide derivative for improved antimicrobial activity.

scientific article published on 25 November 2017

Calreticulin-independent regulation of the platelet integrin alphaIIbbeta3 by the KVGFFKR alphaIIb-cytoplasmic motif.

scientific article published in February 2004

Cell uptake and cytotoxicity of a novel cyclometalated iridium(III) complex and its octaarginine peptide conjugate.

scientific article published on 10 November 2012

Chemoselective Synthesis of N-Terminal Cysteinyl Thioesters via β,γ-C,S Thiol-Michael Addition

scientific article published on 24 April 2019

Computational approaches to developing short cyclic peptide modulators of protein-protein interactions

scientific article

Computational survey of peptides derived from disulphide-bonded protein loops that may serve as mediators of protein-protein interactions

scientific article

Derivatisation of an Anti-Cancer Cationic Antimicrobial Peptide and its Complexation to Platinum(II)

Derivatisation of buforin IIb, a cationic henicosapeptide, to afford its complexation to platinum(ii) resulting in a novel platinum(ii)-buforin IIb conjugate with anti-cancer activity.

scientific article published on 13 June 2016

Differential In Vitro and In Vivo Toxicities of Antimicrobial Peptide Prodrugs for Potential Use in Cystic Fibrosis.

scientific article

Elucidating the role of Staphylococcus epidermidis serine-aspartate repeat protein G in platelet activation.

scientific article published on 22 May 2009

Eradication of Staphylococcus aureus Biofilm Infections Using Synthetic Antimicrobial Peptides.

scientific article published on March 2017

Hydroxamic Acids: Chemistry, Bioactivity, and Solutionand Solid-Phase Synthesis

In vitro activities of synthetic host defense propeptides processed by neutrophil elastase against cystic fibrosis pathogens

scientific article published on 22 February 2011

Increased intracellular targeting to airway cells using octaarginine-coated liposomes: in vitro assessment of their suitability for inhalation

scientific article published on March 2006

Inhibition of platelet adhesion by peptidomimetics mimicking the interactive β-hairpin of glycoprotein Ibα.

scientific article published on 11 March 2012

Luminescent lanthanide-binding peptides: sensitising the excited states of Eu(III) and Tb(III) with a 1,8-naphthalimide-based antenna

scientific article published on 31 October 2011

Multimodal cell imaging by ruthenium polypyridyl labelled cell penetrating peptides.

scientific article

Parallel synthesis and in vitro activity of novel anthranilic hydroxamate-based inhibitors of the prostaglandin H2 synthase peroxidase activity

scientific article (publication date: 21 October 2005)

Peptide directed transmembrane transport and nuclear localization of Ru(II) polypyridyl complexes in mammalian cells

scientific article published in April 2013

Platinum(iv) oxaliplatin-peptide conjugates targeting memHsp70+ phenotype in colorectal cancer cells.

scientific article

Poly(Ethylene glycol)-based backbones with high peptide loading capacities.

scientific article published on 30 October 2014

Poly(ethylene glycol)-Based Peptidomimetic "PEGtide" of Oligo-Arginine Allows for Efficient siRNA Transfection and Gene Inhibition

scientific article published on 10 June 2019

Polymeric prodrug combination to exploit the therapeutic potential of antimicrobial peptides against cancer cells.

scientific article published in October 2016

Potential of host defense peptide prodrugs as neutrophil elastase-dependent anti-infective agents for cystic fibrosis.

scientific article published on 25 November 2013

Pro-moieties of antimicrobial peptide prodrugs

scientific article published on 13 January 2015

Proteasome inhibition can induce an autophagy-dependent apical activation of caspase-8.

scientific article

Regeneration of aged DMF for use in solid-phase peptide synthesis

scientific article published on 01 January 2019

Regulation of glucose transporter 3 surface expression by the AMP-activated protein kinase mediates tolerance to glutamate excitation in neurons.

scientific article

Ruthenium polypyridyl peptide conjugates: membrane permeable probes for cellular imaging.

scientific article

Stabilization of Angiotensin-(1-7) by key substitution with a cyclic non-natural amino acid.

scientific article published on 25 July 2017

Structural studies in aqueous solution of new binuclear lanthanide luminescent peptide conjugates.

scientific article

Synthesis and assessment of a maleimide functionalized BF2 azadipyrromethene near-infrared fluorochrome.

scientific article published in October 2015

Synthesis of mutual azo prodrugs of anti-inflammatory agents and peptides facilitated by α-aminoisobutyric acid.

scientific article published on 9 November 2011

Targeted antimicrobial peptides.

scientific article published on 5 October 2012

The anti-cancer activity of a cationic anti-microbial peptide derived from monomers of polyhydroxyalkanoate

scientific article published on 21 January 2013

The chain length of biologically produced (R)-3-hydroxyalkanoic acid affects biological activity and structure of anti-cancer peptides.

scientific article

Using Disease-Associated Enzymes to Activate Antimicrobial Peptide Prodrugs

scientific article published in January 2017

Vibrating Mesh Nebulisation of Pro-Antimicrobial Peptides for Use in Cystic Fibrosis.

scientific article published on 17 May 2019

Virtual screening using combinatorial cyclic peptide libraries reveals protein interfaces readily targetable by cyclic peptides.

scientific article published on 20 February 2015

XIAP impairs Smac release from the mitochondria during apoptosis.

scientific article

List of works by Marc C Devocelle

A Theoretical Analysis of the Prodrug Delivery System for Treating Antibiotic-Resistant Bacteria

A computational model of antibiotic-resistance mechanisms in methicillin-resistant Staphylococcus aureus (MRSA).

A convenient parallel synthesis of low molecular weight hydroxamic acids using polymer-supported 1-hydroxybenzotriazole.

A novel family of hydroxamate-based acylating inhibitors of cyclooxygenase

A novel role for the fibrinogen Asn-Gly-Arg (NGR) motif in platelet function.

A peptide affinity column for the identification of integrin alpha IIb-binding proteins

AMP kinase-mediated activation of the BH3-only protein Bim couples energy depletion to stress-induced apoptosis

Absolute Net Charge and the Biological Activity of Oligopeptides

Action of antimicrobial peptides and their prodrugs on model and biological membranes

Assessing the correlation of microscopy-based and volumetry-based measurements for resin swelling in a range of potential greener solvents for SPPS

Benzyl N-[2-(1H-indol-3-yl)eth-yl]dithio-carbamate.

Biosynthesis of 2-aminooctanoic acid and its use to terminally modify a lactoferricin B peptide derivative for improved antimicrobial activity.

Calreticulin-independent regulation of the platelet integrin alphaIIbbeta3 by the KVGFFKR alphaIIb-cytoplasmic motif.

Cell uptake and cytotoxicity of a novel cyclometalated iridium(III) complex and its octaarginine peptide conjugate.

Chemoselective Synthesis of N-Terminal Cysteinyl Thioesters via β,γ-C,S Thiol-Michael Addition

Computational approaches to developing short cyclic peptide modulators of protein-protein interactions

Computational survey of peptides derived from disulphide-bonded protein loops that may serve as mediators of protein-protein interactions

Derivatisation of an Anti-Cancer Cationic Antimicrobial Peptide and its Complexation to Platinum(II)

Derivatisation of buforin IIb, a cationic henicosapeptide, to afford its complexation to platinum(ii) resulting in a novel platinum(ii)-buforin IIb conjugate with anti-cancer activity.

Differential In Vitro and In Vivo Toxicities of Antimicrobial Peptide Prodrugs for Potential Use in Cystic Fibrosis.

Elucidating the role of Staphylococcus epidermidis serine-aspartate repeat protein G in platelet activation.

Eradication of Staphylococcus aureus Biofilm Infections Using Synthetic Antimicrobial Peptides.

Hydroxamic Acids: Chemistry, Bioactivity, and Solutionand Solid-Phase Synthesis

In vitro activities of synthetic host defense propeptides processed by neutrophil elastase against cystic fibrosis pathogens

Increased intracellular targeting to airway cells using octaarginine-coated liposomes: in vitro assessment of their suitability for inhalation

Inhibition of platelet adhesion by peptidomimetics mimicking the interactive β-hairpin of glycoprotein Ibα.

Luminescent lanthanide-binding peptides: sensitising the excited states of Eu(III) and Tb(III) with a 1,8-naphthalimide-based antenna

Multimodal cell imaging by ruthenium polypyridyl labelled cell penetrating peptides.

Parallel synthesis and in vitro activity of novel anthranilic hydroxamate-based inhibitors of the prostaglandin H2 synthase peroxidase activity

Peptide directed transmembrane transport and nuclear localization of Ru(II) polypyridyl complexes in mammalian cells

Platinum(iv) oxaliplatin-peptide conjugates targeting memHsp70+ phenotype in colorectal cancer cells.

Poly(Ethylene glycol)-based backbones with high peptide loading capacities.

Poly(ethylene glycol)-Based Peptidomimetic "PEGtide" of Oligo-Arginine Allows for Efficient siRNA Transfection and Gene Inhibition

Polymeric prodrug combination to exploit the therapeutic potential of antimicrobial peptides against cancer cells.

Potential of host defense peptide prodrugs as neutrophil elastase-dependent anti-infective agents for cystic fibrosis.

Pro-moieties of antimicrobial peptide prodrugs

Proteasome inhibition can induce an autophagy-dependent apical activation of caspase-8.

Regeneration of aged DMF for use in solid-phase peptide synthesis

Regulation of glucose transporter 3 surface expression by the AMP-activated protein kinase mediates tolerance to glutamate excitation in neurons.

Ruthenium polypyridyl peptide conjugates: membrane permeable probes for cellular imaging.

Stabilization of Angiotensin-(1-7) by key substitution with a cyclic non-natural amino acid.

Structural studies in aqueous solution of new binuclear lanthanide luminescent peptide conjugates.

Synthesis and assessment of a maleimide functionalized BF2 azadipyrromethene near-infrared fluorochrome.

Synthesis of mutual azo prodrugs of anti-inflammatory agents and peptides facilitated by α-aminoisobutyric acid.

Targeted antimicrobial peptides.

The anti-cancer activity of a cationic anti-microbial peptide derived from monomers of polyhydroxyalkanoate

The chain length of biologically produced (R)-3-hydroxyalkanoic acid affects biological activity and structure of anti-cancer peptides.

Using Disease-Associated Enzymes to Activate Antimicrobial Peptide Prodrugs

Vibrating Mesh Nebulisation of Pro-Antimicrobial Peptides for Use in Cystic Fibrosis.

Virtual screening using combinatorial cyclic peptide libraries reveals protein interfaces readily targetable by cyclic peptides.

XIAP impairs Smac release from the mitochondria during apoptosis.