List of works - James Mu

A glucose-responsive insulin therapy protects animals against hypoglycemia

scientific article published on 11 January 2018

A role for AMP-activated protein kinase in contraction- and hypoxia-regulated glucose transport in skeletal muscle

scientific article (publication date: May 2001)

AMP kinase is not required for the GLUT4 response to exercise and denervation in skeletal muscle.

scientific article

AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation

scientific article

AMP-activated protein kinase mediates ischemic glucose uptake and prevents postischemic cardiac dysfunction, apoptosis, and injury

scientific article published on August 2004

AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus

scientific article

Adipose fibroblast growth factor 21 is up-regulated by peroxisome proliferator-activated receptor gamma and altered metabolic states.

scientific article published on 8 May 2008

Anti-diabetic efficacy and impact on amino acid metabolism of GRA1, a novel small-molecule glucagon receptor antagonist

scientific article

Bone loss in the oestrogen-depleted rat is not exacerbated by sitagliptin, either alone or in combination with a thiazolidinedione.

scientific article published in May 2013

Characterization of human glycogenin-2, a self-glucosylating initiator of liver glycogen metabolism

scientific journal article

Chronic inhibition of dipeptidyl peptidase-4 with a sitagliptin analog preserves pancreatic beta-cell mass and function in a rodent model of type 2 diabetes.

scientific article published in June 2006

Chronic treatment with a glucagon receptor antagonist lowers glucose and moderately raises circulating glucagon and glucagon-like peptide 1 without severe alpha cell hypertrophy in diet-induced obese mice

scientific article published on 22 June 2011

Downstream signaling pathways in mouse adipose tissues following acute in vivo administration of fibroblast growth factor 21

scientific article

Engineering Glucose Responsiveness Into Insulin

scientific article published on 2 November 2017

Exercise induces isoform-specific increase in 5'AMP-activated protein kinase activity in human skeletal muscle.

scientific article published in July 2000

FGF21 analogs of sustained action enabled by orthogonal biosynthesis demonstrate enhanced antidiabetic pharmacology in rodents

scientific article published on 30 December 2011

GLUT4, AMP kinase, but not the insulin receptor, are required for hepatoportal glucose sensor-stimulated muscle glucose utilization

scientific article

Glucagon receptor knockout mice are resistant to diet-induced obesity and streptozotocin-mediated beta cell loss and hyperglycaemia

scientific article published on 28 November 2006

Glycogenin-2, a novel self-glucosylating protein involved in liver glycogen biosynthesis

scientific journal article

Inhibition of DPP-4 with sitagliptin improves glycemic control and restores islet cell mass and function in a rodent model of type 2 diabetes

scientific article published on 16 September 2009

Initiation of glycogen synthesis in yeast. Requirement of multiple tyrosine residues for function of the self-glucosylating Glg proteins in vivo

scientific article published on 01 October 1996

Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta)

scientific article (publication date: June 2001)

Isoform-specific regulation of insulin-dependent glucose uptake by Akt/protein kinase B.

scientific article published on 30 September 2003

Novel aspects of the regulation of glycogen storage.

scientific article

PANIC-ATTAC: a mouse model for inducible and reversible beta-cell ablation

scientific article published on 9 May 2008

Potentiation of insulin-mediated glucose lowering without elevated hypoglycemia risk by a small molecule insulin receptor modulator

scientific article

Requirement of the self-glucosylating initiator proteins Glg1p and Glg2p for glycogen accumulation in Saccharomyces cerevisiae

scientific article

Role of AMP-activated protein kinase in cyclic AMP-dependent lipolysis In 3T3-L1 adipocytes

scientific article published on 25 August 2003

Selective suppression of AMP-activated protein kinase in skeletal muscle: update on 'lazy mice'.

scientific article

Self-glucosylation of glycogenin, the initiator of glycogen biosynthesis, involves an inter-subunit reaction

scientific article published on 01 March 1999

Structure and chromosomal localization of the human glycogenin-2 gene GYG2.

scientific article published on January 2000

The AMP-activated protein kinase alpha2 catalytic subunit controls whole-body insulin sensitivity

scientific article

The PP2A-associated protein alpha4 is an essential inhibitor of apoptosis

scientific article

The glucagon receptor is involved in mediating the body weight-lowering effects of oxyntomodulin.

scientific article published on 16 March 2012

List of works by James Mu

A glucose-responsive insulin therapy protects animals against hypoglycemia

A role for AMP-activated protein kinase in contraction- and hypoxia-regulated glucose transport in skeletal muscle

AMP kinase is not required for the GLUT4 response to exercise and denervation in skeletal muscle.

AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation

AMP-activated protein kinase mediates ischemic glucose uptake and prevents postischemic cardiac dysfunction, apoptosis, and injury

AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus

Adipose fibroblast growth factor 21 is up-regulated by peroxisome proliferator-activated receptor gamma and altered metabolic states.

Anti-diabetic efficacy and impact on amino acid metabolism of GRA1, a novel small-molecule glucagon receptor antagonist

Bone loss in the oestrogen-depleted rat is not exacerbated by sitagliptin, either alone or in combination with a thiazolidinedione.

Characterization of human glycogenin-2, a self-glucosylating initiator of liver glycogen metabolism

Chronic inhibition of dipeptidyl peptidase-4 with a sitagliptin analog preserves pancreatic beta-cell mass and function in a rodent model of type 2 diabetes.

Chronic treatment with a glucagon receptor antagonist lowers glucose and moderately raises circulating glucagon and glucagon-like peptide 1 without severe alpha cell hypertrophy in diet-induced obese mice

Downstream signaling pathways in mouse adipose tissues following acute in vivo administration of fibroblast growth factor 21

Engineering Glucose Responsiveness Into Insulin

Exercise induces isoform-specific increase in 5'AMP-activated protein kinase activity in human skeletal muscle.

FGF21 analogs of sustained action enabled by orthogonal biosynthesis demonstrate enhanced antidiabetic pharmacology in rodents

GLUT4, AMP kinase, but not the insulin receptor, are required for hepatoportal glucose sensor-stimulated muscle glucose utilization

Glucagon receptor knockout mice are resistant to diet-induced obesity and streptozotocin-mediated beta cell loss and hyperglycaemia

Glycogenin-2, a novel self-glucosylating protein involved in liver glycogen biosynthesis

Inhibition of DPP-4 with sitagliptin improves glycemic control and restores islet cell mass and function in a rodent model of type 2 diabetes

Initiation of glycogen synthesis in yeast. Requirement of multiple tyrosine residues for function of the self-glucosylating Glg proteins in vivo

Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta)

Isoform-specific regulation of insulin-dependent glucose uptake by Akt/protein kinase B.

Novel aspects of the regulation of glycogen storage.

PANIC-ATTAC: a mouse model for inducible and reversible beta-cell ablation

Potentiation of insulin-mediated glucose lowering without elevated hypoglycemia risk by a small molecule insulin receptor modulator

Requirement of the self-glucosylating initiator proteins Glg1p and Glg2p for glycogen accumulation in Saccharomyces cerevisiae

Role of AMP-activated protein kinase in cyclic AMP-dependent lipolysis In 3T3-L1 adipocytes

Selective suppression of AMP-activated protein kinase in skeletal muscle: update on 'lazy mice'.

Self-glucosylation of glycogenin, the initiator of glycogen biosynthesis, involves an inter-subunit reaction

Structure and chromosomal localization of the human glycogenin-2 gene GYG2.

The AMP-activated protein kinase alpha2 catalytic subunit controls whole-body insulin sensitivity

The PP2A-associated protein alpha4 is an essential inhibitor of apoptosis

The glucagon receptor is involved in mediating the body weight-lowering effects of oxyntomodulin.