List of works - Richard L Leask

A comparison of mechanical properties of materials used in aortic arch reconstruction

scientific article published on 01 November 2009

Anatomical considerations for the development of a new transcatheter aortopulmonary shunt device in patients with severe pulmonary arterial hypertension

scientific article

Artificial chordae tendinae: long-term changes.

scientific article published in January 2005

Biological replacement heart valves. Identification and evaluation.

scientific article

Biomechanics of the Ascending Thoracic Aorta: A Clinical Perspective on Engineering Data.

scientific article published on 23 October 2015

Blood flow can signal during angiogenesis not only through mechanotransduction, but also by affecting growth factor distribution.

scientific article published on 3 April 2017

Comparative rheology of low- and iso-osmolarity contrast agents at different temperatures.

scientific article published in January 2008

Concentration and time effects of dextran exposure on endothelial cell viability, attachment, and inflammatory marker expression in vitro

scientific article published on 28 January 2010

Designing Green Plasticizers: Linear Alkyl Diol Dibenzoate Plasticizers and a Thermally Reversible Plasticizer

scientific article published on 09 June 2018

Designing green plasticizers: influence of alkyl chain length on biodegradation and plasticization properties of succinate based plasticizers.

scientific article

Designing greener plasticizers: Effects of alkyl chain length and branching on the biodegradation of maleate based plasticizers.

scientific article published on 27 April 2015

Development of a Novel Biodegradable Metallic Stent Based on Microgalvanic Effect.

scientific article published on 18 September 2015

Differential Response of Endothelial Cells to Simvastatin When Conditioned with Steady, Non-Reversing Pulsatile or Oscillating Shear Stress ⬇️

scientific article published on August 25, 2010

Dispersible hydrogel force sensors reveal patterns of solid mechanical stress in multicellular spheroid cultures

scientific article published in Nature Communications

Effect of in vivo flow dynamics on angiogenesis by computational modeling.

scientific article published on August 2015

Effect of simvastatin on Kruppel-like factor2, endothelial nitric oxide synthase and thrombomodulin expression in endothelial cells under shear stress.

scientific article published on 20 May 2010

Effects of di-(2-ethylhexyl) phthalate and four of its metabolites on steroidogenesis in MA-10 cells.

scientific article published on 10 January 2012

Empagliflozin restores the integrity of the endothelial glycocalyx in vitro

scientific article published on 24 May 2019

Endothelial cell morphologic response to asymmetric stenosis hemodynamics: effects of spatial wall shear stress gradients

scientific article published on 01 August 2010

Endothelium and valvular diseases of the heart.

scientific article

Energy loss, a novel biomechanical parameter, correlates with aortic aneurysm size and histopathologic findings

scientific article published on 13 June 2014

Evaluating ascending aortic aneurysm tissue toughness: Dependence on collagen and elastin contents.

scientific article published on 6 August 2016

Evaluation of the effect of stent strut profile on shear stress distribution using statistical moments.

scientific article

Experimental study on local mass transfer in a simplified bifurcation model: potential role in atherosclerosis.

scientific article

Flow dynamics control the location of sprouting and direct elongation during developmental angiogenesis

scientific article published on 9 November 2015

Genetic abnormalities of the endothelium

scientific article

Glycocalyx Degradation Induces a Proinflammatory Phenotype and Increased Leukocyte Adhesion in Cultured Endothelial Cells under Flow

scientific article

Histology and morphology of 59 internal thoracic artery grafts and their distal anastomoses.

scientific article

Histopathological and biomechanical properties of the aortic wall in 2 patients with chronic type A aortic dissection

scientific article published on 30 May 2017

Host tissue overgrowth in a mitral valve conserving procedure

scientific article published on 01 March 2003

How Green is Your Plasticizer?

scientific article published on 28 July 2018

Human saphenous vein coronary artery bypass graft morphology, geometry and hemodynamics.

scientific article

Impact of the cell life-cycle on bacteriophage T4 infection.

scientific article published on April 2014

In vitro comparison of Günther Tulip and Celect filters: testing filtering efficiency and pressure drop

scientific article published on 16 December 2014

In vitro hemodynamic evaluation of a Simon nitinol vena cava filter: possible explanation of IVC occlusion

scientific article published on 01 May 2001

Increased MMP activity in curved geometries disrupts the endothelial cell glycocalyx creating a proinflammatory environment

scientific article published in PLoS ONE

Investigation on the Regional Loss Factor and Its Anisotropy for Aortic Aneurysms.

scientific article published on 26 October 2016

Invited commentary

scientific article published in March 2006

Laminar shear stress prevents simvastatin-induced adhesion molecule expression in cytokine activated endothelial cells.

scientific article published on 19 September 2010

Leaching of the plasticizer di(2-ethylhexyl)phthalate (DEHP) from plastic containers and the question of human exposure

scientific article

Local mechanical and structural properties of healthy and diseased human ascending aorta tissue.

scientific article published on 5 March 2008

Loss of mechanical directional dependency of the ascending aorta with severe medial degeneration

scientific article published on 15 November 2016

Making it stick: the role of structural design in implantable technologies.

scientific article published on 8 October 2015

Morphological findings in 192 surgically excised native mitral valves.

scientific article published on October 2006

Morphological findings in explanted Toronto stentless porcine valves.

scientific article published in January 2006

Obtaining the biomechanical behavior of ascending aortic aneurysm via the use of novel speckle tracking echocardiography.

scientific article published on 20 December 2016

Pathologic analysis of 19 heart valves with silver-coated sewing rings.

scientific article published in November 2006

Permeabilization of adhered cells using an inert gas jet.

scientific article published on 4 September 2013

Regional dependency of the vascular smooth muscle cell contribution to the mechanical properties of the pig ascending aortic tissue.

scientific article published on 15 May 2010

Regional variations in canine descending aortic tissue mechanical properties change with formalin fixation

scientific article published on 01 February 2012

Robust non-wetting PTFE surfaces by femtosecond laser machining

scientific article

Second harmonic generation microscopy to investigate collagen configuration: a pericarditis case study

scientific article published on 24 July 2009

Simultaneous imaging of blood flow dynamics and vascular remodelling during development

scientific article published on 6 October 2015

Stenosis Hemodynamics Disrupt the Endothelial Cell Glycocalyx by MMP Activity Creating a Proinflammatory Environment

scientific article published on 4 May 2017

The Ross procedure: biomechanical properties of the pulmonary artery according to aortic valve phenotype.

scientific article published on 30 May 2016

The development of 3-D, in vitro, endothelial culture models for the study of coronary artery disease

scientific article published on 28 October 2009

The effect of aortic wall and aortic leaflet stiffening on coronary hemodynamic: a fluid-structure interaction study

scientific article published on 03 April 2013

The effect of simvastatin treatment on endothelial cell response to shear stress and tumor necrosis factor alpha stimulation.

scientific article published on 20 June 2015

The response of human aortic endothelial cells in a stenotic hemodynamic environment: effect of duration, magnitude, and spatial gradients in wall shear stress

scientific article published on 01 July 2010

Therapeutic vascular compliance change may cause significant variation in coronary perfusion: a numerical study.

scientific article published on 5 March 2012

Time-dependent 3D simulations of the hemodynamics in a stented coronary artery

scientific article published on 2 March 2007

Transesophageal echocardiographic strain imaging predicts aortic biomechanics: Beyond diameter.

scientific article published on 11 March 2018

Use of inert gas jets to measure the forces required for mechanical gene transfection

scientific article

List of works by Richard L Leask

A comparison of mechanical properties of materials used in aortic arch reconstruction

Anatomical considerations for the development of a new transcatheter aortopulmonary shunt device in patients with severe pulmonary arterial hypertension

Artificial chordae tendinae: long-term changes.

Biological replacement heart valves. Identification and evaluation.

Biomechanics of the Ascending Thoracic Aorta: A Clinical Perspective on Engineering Data.

Blood flow can signal during angiogenesis not only through mechanotransduction, but also by affecting growth factor distribution.

Comparative rheology of low- and iso-osmolarity contrast agents at different temperatures.

Concentration and time effects of dextran exposure on endothelial cell viability, attachment, and inflammatory marker expression in vitro

Designing Green Plasticizers: Linear Alkyl Diol Dibenzoate Plasticizers and a Thermally Reversible Plasticizer

Designing green plasticizers: influence of alkyl chain length on biodegradation and plasticization properties of succinate based plasticizers.

Designing greener plasticizers: Effects of alkyl chain length and branching on the biodegradation of maleate based plasticizers.

Development of a Novel Biodegradable Metallic Stent Based on Microgalvanic Effect.

Differential Response of Endothelial Cells to Simvastatin When Conditioned with Steady, Non-Reversing Pulsatile or Oscillating Shear Stress ⬇️

Dispersible hydrogel force sensors reveal patterns of solid mechanical stress in multicellular spheroid cultures

Effect of in vivo flow dynamics on angiogenesis by computational modeling.

Effect of simvastatin on Kruppel-like factor2, endothelial nitric oxide synthase and thrombomodulin expression in endothelial cells under shear stress.

Effects of di-(2-ethylhexyl) phthalate and four of its metabolites on steroidogenesis in MA-10 cells.

Empagliflozin restores the integrity of the endothelial glycocalyx in vitro

Endothelial cell morphologic response to asymmetric stenosis hemodynamics: effects of spatial wall shear stress gradients

Endothelium and valvular diseases of the heart.

Energy loss, a novel biomechanical parameter, correlates with aortic aneurysm size and histopathologic findings

Evaluating ascending aortic aneurysm tissue toughness: Dependence on collagen and elastin contents.

Evaluation of the effect of stent strut profile on shear stress distribution using statistical moments.

Experimental study on local mass transfer in a simplified bifurcation model: potential role in atherosclerosis.

Flow dynamics control the location of sprouting and direct elongation during developmental angiogenesis

Genetic abnormalities of the endothelium

Glycocalyx Degradation Induces a Proinflammatory Phenotype and Increased Leukocyte Adhesion in Cultured Endothelial Cells under Flow

Histology and morphology of 59 internal thoracic artery grafts and their distal anastomoses.

Histopathological and biomechanical properties of the aortic wall in 2 patients with chronic type A aortic dissection

Host tissue overgrowth in a mitral valve conserving procedure

How Green is Your Plasticizer?

Human saphenous vein coronary artery bypass graft morphology, geometry and hemodynamics.

Impact of the cell life-cycle on bacteriophage T4 infection.

In vitro comparison of Günther Tulip and Celect filters: testing filtering efficiency and pressure drop

In vitro hemodynamic evaluation of a Simon nitinol vena cava filter: possible explanation of IVC occlusion

Increased MMP activity in curved geometries disrupts the endothelial cell glycocalyx creating a proinflammatory environment

Investigation on the Regional Loss Factor and Its Anisotropy for Aortic Aneurysms.

Invited commentary

Laminar shear stress prevents simvastatin-induced adhesion molecule expression in cytokine activated endothelial cells.

Leaching of the plasticizer di(2-ethylhexyl)phthalate (DEHP) from plastic containers and the question of human exposure

Local mechanical and structural properties of healthy and diseased human ascending aorta tissue.

Loss of mechanical directional dependency of the ascending aorta with severe medial degeneration

Making it stick: the role of structural design in implantable technologies.

Morphological findings in 192 surgically excised native mitral valves.

Morphological findings in explanted Toronto stentless porcine valves.

Obtaining the biomechanical behavior of ascending aortic aneurysm via the use of novel speckle tracking echocardiography.

Pathologic analysis of 19 heart valves with silver-coated sewing rings.

Permeabilization of adhered cells using an inert gas jet.

Regional dependency of the vascular smooth muscle cell contribution to the mechanical properties of the pig ascending aortic tissue.

Regional variations in canine descending aortic tissue mechanical properties change with formalin fixation

Robust non-wetting PTFE surfaces by femtosecond laser machining

Second harmonic generation microscopy to investigate collagen configuration: a pericarditis case study

Simultaneous imaging of blood flow dynamics and vascular remodelling during development

Stenosis Hemodynamics Disrupt the Endothelial Cell Glycocalyx by MMP Activity Creating a Proinflammatory Environment

The Ross procedure: biomechanical properties of the pulmonary artery according to aortic valve phenotype.

The development of 3-D, in vitro, endothelial culture models for the study of coronary artery disease

The effect of aortic wall and aortic leaflet stiffening on coronary hemodynamic: a fluid-structure interaction study

The effect of simvastatin treatment on endothelial cell response to shear stress and tumor necrosis factor alpha stimulation.

The response of human aortic endothelial cells in a stenotic hemodynamic environment: effect of duration, magnitude, and spatial gradients in wall shear stress

Therapeutic vascular compliance change may cause significant variation in coronary perfusion: a numerical study.

Time-dependent 3D simulations of the hemodynamics in a stented coronary artery

Transesophageal echocardiographic strain imaging predicts aortic biomechanics: Beyond diameter.

Use of inert gas jets to measure the forces required for mechanical gene transfection