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List of works by George Poulogiannis

Asparagine bioavailability governs metastasis in a model of breast cancer

scientific article published on 7 February 2018

Conditional expression of mutated K-ras accelerates intestinal tumorigenesis in Msh2-deficient mice

scientific article published on 05 February 2007

DNA Damage, Repair, and Cancer Metabolism.

scientific article published on 5 February 2018

DNA mismatch repair deficiency in sporadic colorectal cancer and Lynch syndrome.

scientific article published on January 2010

Deconstructing the Metabolic Networks of Oncogenic Signaling Using Targeted Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS).

scientific article published in January 2017

Decreased function of survival motor neuron protein impairs endocytic pathways.

scientific article published on 11 July 2016

Depletion of a putatively druggable class of phosphatidylinositol kinases inhibits growth of p53-null tumors

scientific article

Discovery of naturally occurring ESR1 mutations in breast cancer cell lines modelling endocrine resistance

scientific article published on 30 November 2017

IRS2 is a candidate driver oncogene on 13q34 in colorectal cancer.

scientific article published on 18 April 2013

Identification of CDCP1 as a hypoxia-inducible factor 2α (HIF-2α) target gene that is associated with survival in clear cell renal cell carcinoma patients

scientific article published on February 2013

Increased tumorigenesis associated with loss of the tumor suppressor gene Cadm1.

scientific article published on 3 May 2012

Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses

scientific article

K-ras exon 4A has a tumour suppressor effect on carcinogen-induced murine colonic adenoma formation.

scientific article published in April 2010

Loss of INPP4B causes a DNA repair defect through loss of BRCA1, ATM and ATR and can be targeted with PARP inhibitor treatment

scientific article published in April 2015

Loss of Rassf1a Synergizes with Deregulated Runx2 Signaling in Tumorigenesis

scientific article published on June 18, 2012

Metabolic adaptability in metastatic breast cancer by AKR1B10-dependent balancing of glycolysis and fatty acid oxidation.

scientific article

Metabolic stress controls mTORC1 lysosomal localization and dimerization by regulating the TTT-RUVBL1/2 complex.

scientific article published on 8 November 2012

Mutant K-ras promotes carcinogen-induced murine colorectal tumourigenesis, but does not alter tumour chromosome stability.

scientific article published on 11 November 2010

Mutated K-ras(Asp12) promotes tumourigenesis in Apc(Min) mice more in the large than the small intestines, with synergistic effects between K-ras and Wnt pathways.

scientific article published in October 2009

Nonsteroidal anti-inflammatory drugs and pain in cancer patients: a systematic review and reappraisal of the evidence

scientific article published on 20 May 2019

Nuclear receptor binding protein 1 regulates intestinal progenitor cell homeostasis and tumour formation

scientific article

Oncogenic KRAS Regulates Tumor Cell Signaling via Stromal Reciprocation.

scientific article published on June 2016

Oncogenic KRAS Regulates Tumor Cell Signaling via Stromal Reciprocation.

scientific article published on 13 April 2016

PARK2 Depletion Connects Energy and Oxidative Stress to PI3K/Akt Activation via PTEN S-Nitrosylation

scientific article published in March 2017

PARK2 deletions occur frequently in sporadic colorectal cancer and accelerate adenoma development in Apc mutant mice.

scientific article

PARK2 loss promotes cancer progression via redox-mediated inactivation of PTEN.

scientific article published on 19 May 2017

Perioperative events influence cancer recurrence risk after surgery.

scientific article published on 28 December 2017

Phosphoinositide 3-Kinase/Akt Signaling and Redox Metabolism in Cancer.

scientific article

Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling

scientific article

Prognostic relevance of DNA copy number changes in colorectal cancer.

scientific article published in February 2010

Proteomics profiling of interactome dynamics by colocalisation analysis (COLA).

scientific article published on 8 November 2016

RAS signalling in the colorectum in health and disease.

scientific article published on 10 January 2012

Synergism between K-rasVal12 and mutant Apc accelerates murine large intestinal tumourigenesis.

scientific article published on 29 April 2011

The SRC-associated protein CUB Domain-Containing Protein-1 regulates adhesion and motility

scientific article

Wild-type K-ras has a tumour suppressor effect on carcinogen-induced murine colorectal adenoma formation

scientific article published on 20 December 2013

p53-independent mechanisms regulate the P2-MDM2 promoter in adult astrocytic tumours

scientific article published on 09 September 2008