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List of works by Ralf B Schittenhelm

A Metabolic Checkpoint for the Yeast-to-Hyphae Developmental Switch Regulated by Endogenous Nitric Oxide Signaling

scientific article published on 01 November 2018

A Systems Approach to Understand Antigen Presentation and the Immune Response.

scientific article published in January 2016

A comprehensive analysis of constitutive naturally processed and presented HLA-C*04:01 (Cw4)-specific peptides.

scientific article published on 7 January 2014

A comprehensive analysis of peptides presented by HLA-A1.

scientific article

A prominent role of PDIA6 in processing of misfolded proinsulin

scientific article published on 03 March 2016

AgRP Neurons Require Carnitine Acetyltransferase to Regulate Metabolic Flexibility and Peripheral Nutrient Partitioning

scientific article published in February 2018

Allelic association with ankylosing spondylitis fails to correlate with human leukocyte antigen B27 homodimer formation

scientific article published on 18 November 2019

An open-source computational and data resource to analyze digital maps of immunopeptidomes

scientific article

Antibiotic-chemoattractants enhance neutrophil clearance of Staphylococcus aureus

scientific article published on 25 October 2021

Assembly of the secretion pores GspD, Wza and CsgG into bacterial outer membranes does not require the Omp85 proteins BamA or TamA.

scientific article published on 14 May 2015

Atmospheric carbon monoxide oxidation is a widespread mechanism supporting microbial survival

scientific article published on 29 July 2019

Aurora Kinase B, a novel regulator of TERF1 binding and telomeric integrity

scientific article published on 10 October 2017

Biochemical membrane lipidomics during Drosophila development.

scientific article published on 20 December 2012

Biodosimetric transcriptional and proteomic changes are conserved in irradiated human tissue

scientific article published on 30 May 2018

Characterization of the Src-regulated kinome identifies SGK1 as a key mediator of Src-induced transformation

scientific article published in Nature Communications

Chlorinated Glycopeptide Antibiotic Peptide Precursors Improve Cytochrome P450-Catalyzed Cyclization Cascade Efficiency

scientific article published on 20 February 2017

Comprehensive characterization of distinct states of human naive pluripotency generated by reprogramming

scientific article published on 25 September 2017

Deep proteomic profiling unveils arylsulfatase A as a non-alcoholic steatohepatitis inducible hepatokine and regulator of glycemic control

scientific article published on 10 March 2022

Determination of the small RNA GcvB regulon in the Gram-negative bacterial pathogen Pasteurella multocida and identification of the GcvB seed binding region.

scientific article published on 12 February 2018

Detrimental incorporation of excess Cenp-A/Cid and Cenp-C into Drosophila centromeres is prevented by limiting amounts of the bridging factor Cal1.

scientific article published on 12 October 2010

Enzymatic Cascade To Evaluate the Tricyclization of Glycopeptide Antibiotic Precursor Peptides as a Prequel to Biosynthetic Redesign

scientific article published on 11 October 2019

Exploring the Tetracyclization of Teicoplanin Precursor Peptides through Chemoenzymatic Synthesis

scientific article published on 11 December 2019

Exploring the oncoproteomic response of human prostate cancer to therapeutic radiation using data-independent acquisition (DIA) mass spectrometry

scientific article published on 09 March 2018

Genetic interactions of separase regulatory subunits reveal the diverged Drosophila Cenp-C homolog.

scientific article published on September 2005

Halogenation of glycopeptide antibiotics occurs at the amino acid level during non-ribosomal peptide synthesis

scientific article

Human Leukocyte Antigen (HLA) B27 Allotype-Specific Binding and Candidate Arthritogenic Peptides Revealed through Heuristic Clustering of Data-independent Acquisition Mass Spectrometry (DIA-MS) Data

scientific article

INPP4B promotes PI3Kα-dependent late endosome formation and Wnt/β-catenin signaling in breast cancer

scientific article published on 25 May 2021

Identification of Metabolically Distinct Adipocyte Progenitor Cells in Human Adipose Tissues

scientific article published on 01 April 2019

Identification of Novel Acinetobacter baumannii Type VI Secretion System Anti-Bacterial Effector and Immunity Pairs.

scientific article

Kistamicin biosynthesis reveals the biosynthetic requirements for production of highly crosslinked glycopeptide antibiotics

scientific article published on 13 June 2019

LFQ-Analyst: An Easy-To-Use Interactive Web Platform To Analyze and Visualize Label-Free Proteomics Data Preprocessed with MaxQuant

scientific article published on 08 November 2019

Ligand-dependent spatiotemporal signaling profiles of the μ-opioid receptor are controlled by distinct protein-interaction networks

scientific article published on 12 September 2019

Mismatch in epitope specificities between IFNγ inflamed and uninflamed conditions leads to escape from T lymphocyte killing in melanoma.

scientific article published on 16 February 2016

Mitochondrial dysfunction caused by outer membrane vesicles from Gram-negative bacteria activates intrinsic apoptosis and inflammation

scientific article published on 17 August 2020

Modularity and hormone sensitivity of the Drosophila melanogaster insulin receptor/target of rapamycin interaction proteome

scientific article published on 8 November 2011

Molecular Basis of Unexpected Specificity of ABC Transporter-Associated Substrate-Binding Protein DppA from Helicobacter pylori

scientific article published on 20 September 2019

Multi-functional regulation of 4E-BP gene expression by the Ccr4-Not complex

scientific article published on 20 March 2015

Perilipin 5 S155 phosphorylation by PKA is required for the control of hepatic lipid metabolism and glycemic control

scientific article published on 17 December 2020

Phosphoproteomic characterization of the signaling network resulting from activation of chemokine receptor CCR2

scientific article published on 02 April 2020

Proteomic Identification of Interferon-Induced Proteins with Tetratricopeptide Repeats as Markers of M1 Macrophage Polarization.

scientific article published on 6 March 2018

Proteotranscriptomic measurements of E6-Associated Protein (E6AP) targets in DU145 prostate cancer cells.

scientific article published on 20 February 2018

RNA exploits an exposed regulatory site to inhibit the enzymatic activity of PRC2

scientific article published on 04 March 2019

Restriction of essential amino acids dictates the systemic metabolic response to dietary protein dilution

scientific article published on 09 June 2020

Revisiting the arthritogenic peptide theory: quantitative not qualitative changes in the peptide repertoire of HLA-B27 allotypes

scientific article

SMOC1 is a glucose-responsive hepatokine and therapeutic target for glycemic control

scientific article published on 01 September 2020

Simultaneous Quantification of Viral Antigen Expression Kinetics Using Data-Independent (DIA) Mass Spectrometry.

scientific article

Spatial organization of a ubiquitous eukaryotic kinetochore protein network in Drosophila chromosomes

scientific article published on March 2007

Spliced Peptides and Cytokine-Driven Changes in the Immunopeptidome of Melanoma

scientific article published on 16 September 2020

Structural basis for substrate selection by the translocation and assembly module of the β-barrel assembly machinery

scientific article

Structures of a non-ribosomal peptide synthetase condensation domain suggest the basis of substrate selectivity

scientific article published on 04 May 2021

Suppressing fatty acid uptake has therapeutic effects in preclinical models of prostate cancer

scientific article published on 01 February 2019

The Diiron Monooxygenase CmlA from Chloramphenicol Biosynthesis Allows Reconstitution of β-Hydroxylation during Glycopeptide Antibiotic Biosynthesis

scientific article published on 10 December 2019

The RSC (Remodels the Structure of Chromatin) complex of Candida albicans shows compositional divergence with distinct roles in regulating pathogenic traits

scientific article published on 05 November 2020

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