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List of works by Hesham M Korashy

Alpha-lipoic acid rebalances redox and immune-testicular milieu in septic rats ⬇️

scientific article published on December 30, 2010

Aryl hydrocarbon receptor/cytochrome P450 1A1 pathway mediates breast cancer stem cells expansion through PTEN inhibition and β-Catenin and Akt activation

scientific article (publication date: 19 January 2017)

BCL-2 Inhibitor Venetoclax Induces Autophagy-Associated Cell Death, Cell Cycle Arrest, and Apoptosis in Human Breast Cancer Cells

scientific article published on 31 December 2020

Benzo[a]pyrene, 3-methylcholanthrene and beta-naphthoflavone induce oxidative stress in hepatoma hepa 1c1c7 Cells by an AHR-dependent pathway.

scientific article

Camel Milk Triggers Apoptotic Signaling Pathways in Human Hepatoma HepG2 and Breast Cancer MCF7 Cell Lines through Transcriptional Mechanism ⬇️

scientific article published on May 13, 2012

Camel milk attenuates the biochemical and morphological features of diabetic nephropathy: inhibition of Smad1 and collagen type IV synthesis.

scientific article published on 21 January 2015

Camel milk modulates the expression of aryl hydrocarbon receptor-regulated genes, Cyp1a1, Nqo1, and Gsta1, in murine hepatoma Hepa 1c1c7 cells.

scientific article

Camel urine inhibits the cytochrome P450 1a1 gene expression through an AhR-dependent mechanism in Hepa 1c1c7 cell line.

scientific article published on 29 September 2010

Dasatinib.

scientific article

Design and Synthesis of N-Arylphthalimides as Inhibitors of Glucocorticoid-Induced TNF Receptor-Related Protein, Proinflammatory Mediators, and Cytokines in Carrageenan-Induced Lung Inflammation.

scientific article published on 10 October 2015

Development of cardiac hypertrophy by sunitinib in vivo and in vitro rat cardiomyocytes is influenced by the aryl hydrocarbon receptor signaling pathway

scientific article published on 19 November 2013

Dexamethasone Attenuates LPS-induced Acute Lung Injury through Inhibition of NF-κB, COX-2, and Pro-inflammatory Mediators

scientific article published on 22 April 2016

Differential Effects of Sunitinib on the Expression Profiles of Xenobiotic-Metabolizing Enzymes and Transporters in Rat Liver and Kidneys.

scientific article published on 16 February 2016

Differential effects of mercury, lead and copper on the constitutive and inducible expression of aryl hydrocarbon receptor (AHR)-regulated genes in cultured hepatoma Hepa 1c1c7 cells.

scientific article

Downregulation of the cardiotrophin-1 gene expression by valsartan and spironolactone in hypertrophied heart rats in vivo and rat cardiomyocyte H9c2 cell line in vitro: a novel mechanism of cardioprotection.

scientific article

Effect of long-term human exposure to environmental heavy metals on the expression of detoxification and DNA repair genes ⬇️

scientific article published on July 17, 2013

Effects of renal diseases on the regulation and expression of renal and hepatic drug-metabolizing enzymes: a review.

scientific article published on January 2004

Endoplasmic Reticulum Stress: A Critical Molecular Driver of Endothelial Dysfunction and Cardiovascular Disturbances Associated with Diabetes ⬇️

scientific article published on 03 April 2019

Erratum to: Aryl hydrocarbon receptor/cytochrome P450 1A1 pathway mediates breast cancer stem cells expansion through PTEN inhibition and β-Catenin and Akt activation

scientific article published on 24 March 2017

FoxO3a is Essential for the Antiproliferative and Apoptogenic Effects of Sunitinib in MDA-MB231 Cell Line.

scientific article published on November 2016

Gefitinib

scientific article published on 01 January 2014

Gene expression profiling to identify the toxicities and potentially relevant human disease outcomes associated with environmental heavy metal exposure.

scientific article published on December 2016

Genotoxic Impact of Long-term Cigarette and Waterpipe Smoking on DNA Damage and Oxidative Stress in Healthy Subjects

scientific article published on 18 December 2018

Gold-containing compound BDG-I inhibits the growth of A549 lung cancer cells through the deregulation of miRNA expression.

scientific article published on 6 June 2018

High-performance liquid chromatographic method for the determination of dasatinib in rabbit plasma using fluorescence detection and its application to a pharmacokinetic study.

scientific article

Impact of Herbal Medicines like Nigella sativa, Trigonella foenum-graecum, and Ferula asafoetida, on Cytochrome P450 2C11 Gene Expression in Rat Liver

scientific article published on 06 August 2014

Impact of cigarette smoke exposure on the expression of cardiac hypertrophic genes, cytochrome P450 enzymes, and oxidative stress markers in rats.

scientific article published in January 2012

Induction of the NAD(P)H:quinone oxidoreductase 1 by ketoconazole and itraconazole: a mechanism of cancer chemoprotection.

scientific article published on 17 October 2007

Interplay between Endoplasmic Reticulum Stress and Large Extracellular Vesicles (Microparticles) in Endothelial Cell Dysfunction

scientific article published on 12 October 2020

Ketoconazole Stereoisomers Differentially Induce Cytochrome P450 1A1 Between Human Hepatoma HepG2 and Mouse Hepatoma Hepa1c1c7 Cells.

scientific article published on 06 February 2016

Lepidium sativum but not Nigella sativa affects carbamazepine disposition in an animal model.

scientific article

Meteorological Factors and Seasonal Stroke Rates: A Four-year Comprehensive Study

scientific article published on 18 June 2019

Metformin attenuates streptozotocin-induced diabetic nephropathy in rats through modulation of oxidative stress genes expression.

scientific article published on 30 March 2011

Metformin inhibits 7,12-dimethylbenz[a]anthracene-induced breast carcinogenesis and adduct formation in human breast cells by inhibiting the cytochrome P4501A1/aryl hydrocarbon receptor signaling pathway.

scientific article

Metformin rescues the myocardium from doxorubicin-induced energy starvation and mitochondrial damage in rats

scientific article

Mitogen-activated protein kinases pathways mediate the sunitinib-induced hypertrophy in rat cardiomyocyte H9c2 cells.

scientific article

Modulation of TCDD-mediated induction of cytochrome P450 1A1 by mercury, lead, and copper in human HepG2 cell line.

scientific article

Molecular Mechanisms of Adiponectin-Induced Attenuation of Mechanical Stretch-Mediated Vascular Remodeling

scientific article published on 21 May 2020

Molecular mechanisms of cardiotoxicity of gefitinib in vivo and in vitro rat cardiomyocyte: Role of apoptosis and oxidative stress.

scientific article published on 12 April 2016

NF-kappaB and AP-1 are key signaling pathways in the modulation of NAD(P)H:quinone oxidoreductase 1 gene by mercury, lead, and copper.

scientific article

Naringin attenuates the development of carrageenan-induced acute lung inflammation through inhibition of NF-κb, STAT3 and pro-inflammatory mediators and enhancement of IκBα and anti-inflammatory cytokines.

scientific article published on April 2015

Pharmacokinetic interaction studies of fenugreek with CYP3A substrates cyclosporine and carbamazepine.

scientific article

Phloretin attenuates STAT-3 activity and overcomes sorafenib resistance targeting SHP-1-mediated inhibition of STAT3 and Akt/VEGFR2 pathway in hepatocellular carcinoma

scientific article published on 16 October 2019

Regulation of TNF-α and NF-κB activation through the JAK/STAT signaling pathway downstream of histamine 4 receptor in a rat model of LPS-induced joint inflammation.

scientific article

Riboflavin attenuates lipopolysaccharide-induced lung injury in rats.

scientific article

Role of RAS signaling in ovarian cancer

scientific article published in 2022

Rutin Attenuates Carfilzomib-Induced Cardiotoxicity Through Inhibition of NF-κB, Hypertrophic Gene Expression and Oxidative Stress.

scientific article published in January 2017

Salubrious effects of dexrazoxane against teniposide-induced DNA damage and programmed cell death in murine marrow cells ⬇️

scientific article published on March 23, 2011

Sinapic acid mitigates gentamicin-induced nephrotoxicity and associated oxidative/nitrosative stress, apoptosis, and inflammation in rats.

scientific article published on 21 September 2016

Stimulation of the histamine 4 receptor with 4-methylhistamine modulates the effects of chronic stress on the Th1/Th2 cytokine balance.

scientific article published on 24 October 2014

Sunitinib Inhibits Breast Cancer Cell Proliferation by Inducing Apoptosis, Cell-cycle Arrest and DNA Repair While Inhibiting NF-κB Signaling Pathways.

scientific article published in September 2017

Sunitinib Malate

scientific article published on March 19, 2012

Sunitinib, a tyrosine kinase inhibitor, induces cytochrome P450 1A1 gene in human breast cancer MCF7 cells through ligand-independent aryl hydrocarbon receptor activation ⬇️

scientific article published on January 4, 2013

The Role of Protein Tyrosine Phosphatase (PTP)-1B in Cardiovascular Disease and Its Interplay with Insulin Resistance

scientific article published on 17 July 2019

The effect of liver cirrhosis on the regulation and expression of drug metabolizing enzymes.

scientific article published on April 2004

The impact of experimental hyperlipidemia on the distribution and metabolism of amiodarone in rat.

scientific article published on 27 May 2008

The p38 MAPK inhibitor SB203580 induces cytochrome P450 1A1 gene expression in murine and human hepatoma cell lines through ligand-dependent aryl hydrocarbon receptor activation

scientific article published on 27 July 2011

The role of NF-κB and AhR transcription factors in lead-induced lung toxicity in human lung cancer A549 cells

scientific article published on 20 November 2019

The role of aryl hydrocarbon receptor in the pathogenesis of cardiovascular diseases.

scientific article

The role of aryl hydrocarbon receptor signaling pathway in cardiotoxicity of acute lead intoxication in vivo and in vitro rat model.

scientific article published on 5 February 2013

The role of poly(ADP-ribose) polymerase-1 inhibitor in carrageenan-induced lung inflammation in mice.

scientific article

The role of redox-sensitive transcription factors NF-kappaB and AP-1 in the modulation of the Cyp1a1 gene by mercury, lead, and copper.

scientific article published on 17 November 2007

Therapeutic potential of carfilzomib, an irreversible proteasome inhibitor, against acetaminophen-induced hepatotoxicity in mice.

scientific article published on 30 November 2016

Thymoquinone suppression of the human hepatocellular carcinoma cell growth involves inhibition of IL-8 expression, elevated levels of TRAIL receptors, oxidative stress and apoptosis.

scientific article published on 8 January 2014

Transcriptional and posttranslational mechanisms modulating the expression of the cytochrome P450 1A1 gene by lead in HepG2 cells: a role of heme oxygenase.

scientific article

Transcriptional regulation of the NAD(P)H:quinone oxidoreductase 1 and glutathione S-transferase ya genes by mercury, lead, and copper.

scientific article published on 21 October 2005

Treatment with aliskiren ameliorates tacrolimus-induced nephrotoxicity in rats

scientific article published on 15 April 2014

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