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List of works by Paul T Pfluger

A BAFF/APRIL axis regulates obesogenic diet-driven weight gain

scientific article published on 18 May 2021

A functional role for the p62-ERK1 axis in the control of energy homeostasis and adipogenesis

scientific article

A guide to analysis of mouse energy metabolism

scientific article published on 28 December 2011

A new glucagon and GLP-1 co-agonist eliminates obesity in rodents

scientific article

A novel human-based receptor antagonist of sustained action reveals body weight control by endogenous GLP-1.

scientific article published on 4 November 2010

A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodents

scientific article published on 8 December 2014

Ablation of ghrelin O-acyltransferase does not improve glucose intolerance or body adiposity in mice on a leptin-deficient ob/ob background

scientific article

Action profile of the antiobesity drug candidate oleoyl-estrone in rats

scientific article published on 25 March 2010

Acylation type determines ghrelin's effects on energy homeostasis in rodents

scientific article

Adipocyte LDL receptor-related protein-1 expression modulates postprandial lipid transport and glucose homeostasis in mice

scientific article

Alterations in neuronal control of body weight and anxiety behavior by glutathione peroxidase 4 deficiency

scientific article published on 13 June 2017

Astrocytic Insulin Signaling Couples Brain Glucose Uptake with Nutrient Availability

scientific article

Both acyl and des-acyl ghrelin regulate adiposity and glucose metabolism via central nervous system ghrelin receptors

scientific article published on 23 September 2013

Bsx, a novel hypothalamic factor linking feeding with locomotor activity, is regulated by energy availability

scientific article

Calcineurin A beta deficiency ameliorates HFD-induced hypothalamic astrocytosis in mice

scientific article published on 8 February 2018

Calcineurin Links Mitochondrial Elongation with Energy Metabolism

scientific article

Caloric restriction chronically impairs metabolic programming in mice

scientific article

Carbohydrate content of post-operative diet influences the effect of vertical sleeve gastrectomy on body weight reduction in obese rats

scientific article published in January 2012

Carotenoids and their metabolites are naturally occurring activators of gene expression via the pregnane X receptor

scientific article

Celastrol-Induced Weight Loss Is Driven by Hypophagia and Independent From UCP1

scientific article published on 28 August 2018

Comprehensive analysis of nine monoamines and metabolites in small amounts of peripheral murine (C57Bl/6 J) tissues

scientific article published on 22 November 2017

Diabetes type 2 risk gene Dusp8 is associated with altered sucrose reward behavior in mice and humans

scientific article published on 01 November 2020

Differential colonization with segmented filamentous bacteria and Lactobacillus murinus do not drive divergent development of diet-induced obesity in C57BL/6 mice

scientific article published on 10 May 2013

Direct Substrate Delivery Into Mitochondrial Fission-Deficient Pancreatic Islets Rescues Insulin Secretion

scientific article published on 7 February 2017

Direct control of peripheral lipid deposition by CNS GLP-1 receptor signaling is mediated by the sympathetic nervous system and blunted in diet-induced obesity

scientific article published in May 2009

Dual specificity phosphatase 6 deficiency is associated with impaired systemic glucose tolerance and reversible weight retardation in mice

scientific article

Duodenal nutrient exclusion improves metabolic syndrome and stimulates villus hyperplasia

scientific article published on 09 October 2013

Dusp8 affects hippocampal size and behavior in mice and humans

scientific article published on 20 December 2019

Effects of obestatin on energy balance and growth hormone secretion in rodents

scientific article published on 28 September 2006

FGF21 is not required for glucose homeostasis, ketosis or tumour suppression associated with ketogenic diets in mice

scientific article published on 23 June 2015

Fibroblast growth factor 21 mediates specific glucagon actions

scientific article published on 10 January 2013

Fluorescent blood-brain barrier tracing shows intact leptin transport in obese mice

scientific article published on 03 October 2018

GLP-1R agonism enhances adjustable gastric banding in diet-induced obese rats

scientific article published on 17 June 2013

GLP-1R responsiveness predicts individual gastric bypass efficacy on glucose tolerance in rats

scientific article

GOAT links dietary lipids with the endocrine control of energy balance

scientific article published on 05 June 2009

GOAT: the master switch for the ghrelin system?

scientific article published on 26 April 2010

Gastric O-acyl transferase activates hunger signal to the brain

scholarly article

Gastric bypass surgery attenuates ethanol consumption in ethanol-preferring rats

scientific article published on 22 March 2012

Gastric bypass surgery for treatment of hypothalamic obesity after craniopharyngioma therapy

scientific article published in August 2007

Genetic variation of the ghrelin activator gene ghrelin O-acyltransferase (GOAT) is associated with anorexia nervosa

scientific article

Ghrelin Receptor Deficiency does not Affect Diet-Induced Atherosclerosis in Low-Density Lipoprotein Receptor-Null Mice

scientific article

Ghrelin action in the brain controls adipocyte metabolism

scientific article

Ghrelin and PYY in the regulation of energy balance and metabolism: lessons from mouse mutants

scientific article published on 23 February 2010

Ghrelin and its potential in the treatment of eating/wasting disorders and cachexia

scientific article

Ghrelin enhances olfactory sensitivity and exploratory sniffing in rodents and humans

scientific article

Ghrelin-induced adiposity is independent of orexigenic effects

scientific article

Glucagon regulation of energy metabolism

scientific article published on 08 April 2010

Glucose and weight control in mice with a designed ghrelin O-acyltransferase inhibitor

scientific article

High calorie diet triggers hypothalamic angiopathy

scientific article published on 9 August 2012

High-density lipoprotein maintains skeletal muscle function by modulating cellular respiration in mice

scientific article published on 29 October 2013

High-fat-diet-induced obesity causes an inflammatory and tumor-promoting microenvironment in the rat kidney

scientific article

Hypothalamic leptin action is mediated by histone deacetylase 5.

scientific article

Improved glucose metabolism in mice lacking alpha-tocopherol transfer protein

scientific article published on 19 September 2007

Intestinal adaptation after ileal interposition surgery increases bile acid recycling and protects against obesity-related comorbidities

scientific article

KSR2 is an essential regulator of AMP kinase, energy expenditure, and insulin sensitivity

scientific article

Light sheet fluorescence microscopy guided MALDI-imaging mass spectrometry of cleared tissue samples

scientific article published on 02 September 2020

Long-term effects of ghrelin and ghrelin receptor agonists on energy balance in rats

scientific article published on 6 May 2008

Low-carbohydrate high-fat diets in combination with daily exercise in rats: effects on body weight regulation, body composition and exercise capacity

scientific article published on 9 February 2012

Melanocortin signaling in the CNS directly regulates circulating cholesterol

scientific article

Metabolic benefits from Sirt1 and Sirt1 activators

scientific article published on July 2009

Metabolic control by S6 kinases depends on dietary lipids

scientific article (publication date: 2012)

Mice with chronically increased circulating ghrelin develop age-related glucose intolerance

scientific article published on 12 February 2008

Modulation of Cyp3a11 mRNA expression by alpha-tocopherol but not gamma-tocotrienol in mice

scientific article published in February 2005

Modulatory calcineurin-interacting proteins 1 and 2 function as calcineurin facilitators in vivo

scientific journal article

Nutropioids, hedonism in the gut?

scientific article published in August 2012

Obesity: will withaferin win the war?

scientific article published in September 2016

Peripheral ghrelin enhances sweet taste food consumption and preference, regardless of its caloric content

scientific article published in June 2010

Postprandial lysophospholipid suppresses hepatic fatty acid oxidation: the molecular link between group 1B phospholipase A2 and diet-induced obesity

scientific article

Regulation of the endosomal SNX27-retromer by OTULIN

scientific article published on 20 September 2019

S6K1 controls pancreatic β cell size independently of intrauterine growth restriction

scientific article

Setting the TRAP for central leptin targets

scientific article published on 6 March 2015

Simultaneous deletion of ghrelin and its receptor increases motor activity and energy expenditure

scientific article published on 29 November 2007

Sirt1 protects against high-fat diet-induced metabolic damage

scholarly article

Systemic ghrelin and reward: Effect of cholinergic blockade ⬇️

scientific article published on December 14, 2010

Targeted estrogen delivery reverses the metabolic syndrome

scientific article

The 1D1 of burning calories.

scientific article published on 23 October 2008

The GOAT-ghrelin system is not essential for hypoglycemia prevention during prolonged calorie restriction

scientific article

The central melanocortin system directly controls peripheral lipid metabolism

scientific article

The effects of vertical sleeve gastrectomy in rodents are ghrelin independent

scientific article

The orphan receptor Gpr83 regulates systemic energy metabolism via ghrelin-dependent and ghrelin-independent mechanisms

scientific article

The role of ghrelin-octanoyl-acyl-transferase in thermoregulation.

scientific article published on 23 April 2012

The role of the transcription factor ETV5 in insulin exocytosis

scientific article

Type 2 diabetes risk gene Dusp8 regulates hypothalamic Jnk signaling and insulin sensitivity

scientific article published on 11 August 2020

Vitamin E activates gene expression via the pregnane X receptor

scientific article

Vitamin E: underestimated as an antioxidant

scientific article

Voluntary exercise improves high-fat diet-induced leptin resistance independent of adiposity

scientific article

p53 in AgRP neurons is required for protection against diet-induced obesity via JNK1

scientific article published in Nature Communications

p62 links β-adrenergic input to mitochondrial function and thermogenesis

scientific article published on 21 December 2012

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