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List of works by Eileen White

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one

scientific article (publication date: November 2016)

A YY1-dependent increase in aerobic metabolism is indispensable for intestinal organogenesis

scientific article published on October 2016

A mouse mammary epithelial cell model to identify molecular mechanisms regulating breast cancer progression

scientific article

A mouse model system to genetically dissect the molecular mechanisms regulating tumorigenesis

scientific article published on September 2006

A noncanonical mechanism of Nrf2 activation by autophagy deficiency: direct interaction between Keap1 and p62.

scientific article published on 26 April 2010

A novel proteomic coculture model of prostate cancer cell growth

scientific article published on October 2004

A randomized phase II trial of mitoxantrone, estramustine and vinorelbine or bcl-2 modulation with 13-cis retinoic acid, interferon and paclitaxel in patients with metastatic castrate-resistant prostate cancer: ECOG 3899.

scientific article published on 24 February 2010

ASAP, a novel protein complex involved in RNA processing and apoptosis

scientific article

Activated H-ras rescues E1A-induced apoptosis and cooperates with E1A to overcome p53-dependent growth arrest

scientific article published on August 1995

Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis.

scientific article

Adenovirus infection of primary malignant lymphoid cells

scientific article

Akt-dependent expression of NAIP-1 protects neurons against amyloid-{beta} toxicity

scientific article published on 29 March 2005

Ammonia derived from glutaminolysis is a diffusible regulator of autophagy

scientific article published on 27 April 2010

Ammonificins A and B, hydroxyethylamine chroman derivatives from a cultured marine hydrothermal vent bacterium, Thermovibrio ammonificans ⬇️

scientific article

Ammonificins C and D, hydroxyethylamine chromene derivatives from a cultured marine hydrothermal vent bacterium, Thermovibrio ammonificans ⬇️

scientific article published on 19 October 2012

An autophagy-dependent anticancer immune response determines the efficacy of melanoma chemotherapy

scientific article published on 3 July 2014

Aneuploidy-induced cellular stresses limit autophagic degradation

scientific article

Apoptosis-inducing galactolipids from a cultured marine diatom, Phaeodactylum tricornutum ⬇️

scientific article

Arsenic inhibits autophagic flux, activating the Nrf2-Keap1 pathway in a p62-dependent manner

scientific article published on 15 April 2013

Assessing metabolic stress and autophagy status in epithelial tumors

scientific article

Association of Bax and Bak homo-oligomers in mitochondria. Bax requirement for Bak reorganization and cytochrome c release

scientific journal article

Atg7 Overcomes Senescence and Promotes Growth of BrafV600E-Driven Melanoma

scientific article

Atg7 cooperates with Pten loss to drive prostate cancer tumor growth

scientific article published on February 2016

Augmentation of apoptosis by the combination of bleomycin with trifluoperazine in the presence of mutant p53

scientific article published on 01 January 2002

Author Correction: Autophagy maintains tumour growth through circulating arginine

scientific article published on 01 January 2019

Autophagic cell death unraveled: Pharmacological inhibition of apoptosis and autophagy enables necrosis

scientific article published on 13 March 2008

Autophagy Suppresses TRP53/p53 and Oxidative Stress to Enable Mammalian Survival

scientific article published on 05 May 2020

Autophagy and Metabolism ⬇️

scientific article (publication date: 3 December 2010)

Autophagy and Tumor Metabolism

scientific article published on May 2017

Autophagy and p53.

scientific article published on April 2016

Autophagy for the avoidance of degenerative, inflammatory, infectious, and neoplastic disease

scientific article

Autophagy in tumorigenesis and energy metabolism: friend by day, foe by night

scientific article published on 20 January 2011

Autophagy is required for glucose homeostasis and lung tumor maintenance

scientific article

Autophagy is required for mitochondrial function, lipid metabolism, growth, and fate of KRAS(G12D)-driven lung tumors

scientific article published on 15 August 2013

Autophagy maintains tumour growth through circulating arginine

scientific article published in Nature

Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis

scientific article published in July 2007

Autophagy opposes p53-mediated tumor barrier to facilitate tumorigenesis in a model of PALB2-associated hereditary breast cancer.

scientific article published on 06 May 2013

Autophagy promotes BrafV600E-driven lung tumorigenesis by preserving mitochondrial metabolism

scientific article published on 17 December 2013

Autophagy promotes growth of tumors with high mutational burden by inhibiting a T-cell immune response

scientific article published on 18 September 2020

Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis

scientific article (publication date: July 2006)

Autophagy provides metabolic substrates to maintain energy charge and nucleotide pools in Ras-driven lung cancer cells

scientific article published on 11 August 2016

Autophagy regulates keratin 8 homeostasis in mammary epithelial cells and in breast tumors

scientific article

Autophagy suppresses RIP kinase-dependent necrosis enabling survival to mTOR inhibition

scientific article

Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis

scientific article published on July 2013

Autophagy suppresses tumor progression by limiting chromosomal instability

scientific article published on 17 May 2007

Autophagy suppresses tumorigenesis through elimination of p62

scientific article

Autophagy sustains mitochondrial glutamine metabolism and growth of BrafV600E-driven lung tumors

scientific article published on 21 August 2013

Autophagy, Metabolism, and Cancer

scientific article

Autophagy, Metabolism, and Cancer

scientific article published in November 2015

Autophagy, stress, and cancer metabolism: what doesn't kill you makes you stronger

scientific article published on January 2011

Autophagy-mediated tumor promotion

scientific article

BAX and BAK mediate p53-independent suppression of tumorigenesis

scientific article published on September 2002

BH3-only proteins in control: specificity regulates MCL-1 and BAK-mediated apoptosis

scientific article

BRAF Fusion as a Novel Mechanism of Acquired Resistance to Vemurafenib in BRAFV600E Mutant Melanoma

scientific article published on 24 May 2017

Bak and Bax function to limit adenovirus replication through apoptosis induction

scientific article

Bathymodiolamides A and B, ceramide derivatives from a deep-sea hydrothermal vent invertebrate mussel, Bathymodiolus thermophilus ⬇️

scientific article

Bax and Bak independently promote cytochrome C release from mitochondria

scientific journal article

Bcl-2 and the ICE family of apoptotic regulators: making a connection.

scientific article published on February 1997

Bcl-2 blocks p53-dependent apoptosis

scientific article published on April 1994

Bcl-2 modulation to activate apoptosis in prostate cancer

scientific article published on 8 September 2009

Bfl-1/A1 functions, similar to Mcl-1, as a selective tBid and Bak antagonist

scientific article published on 3 September 2007

Both viral (adenovirus E1B) and cellular (hsp 70, p53) components interact with centrosomes.

scientific article published on July 1994

Btf, a novel death-promoting transcriptional repressor that interacts with Bcl-2-related proteins

scientific article

Caspase-dependent processing activates the proapoptotic activity of deleted in breast cancer-1 during tumor necrosis factor-alpha-mediated death signaling

scientific article

Control of p53-dependent Apoptosis by E1B, Bcl-2, and Ha-ras Proteins ⬇️

scientific article published on January 1, 1994

Coordinate autophagy and mTOR pathway inhibition enhances cell death in melanoma

scientific article

Correction: Elevated p62/SQSTM1 determines the fate of autophagy-deficient neural stem cells by increasing superoxide

scientific article published on 21 March 2016

DNA damage enables p73

scientific article published in Nature

DNA damage response and MCL-1 destruction initiate apoptosis in adenovirus-infected cells

scientific article

Death-defying acts: a meeting review on apoptosis

scientific article published on 01 December 1993

Deconvoluting the context-dependent role for autophagy in cancer ⬇️

scientific article published on April 26, 2012

Defective ubiquitin-mediated degradation of antiapoptotic Bfl-1 predisposes to lymphoma.

scientific article

Deleted in breast cancer 1, a novel androgen receptor (AR) coactivator that promotes AR DNA-binding activity

scientific article published on 05 January 2009

Does control of mutant p53 by Mdm2 complicate cancer therapy?

scientific article published on May 2008

E1A sensitizes cells to tumor necrosis factor alpha by downregulating c-FLIP S.

scientific article

E1B 19,000-molecular-weight protein interacts with and inhibits CED-4-dependent, FLICE-mediated apoptosis

scientific article published on October 1998

E1B 19K blocks Bax oligomerization and tumor necrosis factor alpha-mediated apoptosis

scientific article

E1B 19K inhibits Fas-mediated apoptosis through FADD-dependent sequestration of FLICE.

scientific article

ERK1/2-dependent phosphorylation of BimEL promotes its rapid dissociation from Mcl-1 and Bcl-xL

scientific article

Eat this, not that! How selective autophagy helps cancer cells survive

scientific article published on 18 March 2015

Eating to exit: autophagy-enabled senescence revealed

scientific article published in April 2009

Effect of dual inhibition of apoptosis and autophagy in prostate cancer

scientific article published on 12 January 2012

Elevated p62/SQSTM1 determines the fate of autophagy-deficient neural stem cells by increasing superoxide

scientific article published on February 2016

Entosis: it's a cell-eat-cell world

scientific article

Epothilone induced cytotoxicity is dependent on p53 status in prostate cells

scientific article published on November 2004

Essential role for p53-mediated transcription in E1A-induced apoptosis ⬇️

scientific article published on September 1, 1995

Essential roles of BCCIP in mouse embryonic development and structural stability of chromosomes

scientific journal article

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015.

scientific article

Exploiting different ways to die.

scientific article published on June 2004

Exploiting the bad eating habits of Ras-driven cancers

scientific article published on October 2013

FLIPping the balance between apoptosis and proliferation in thyroid cancer

scientific article published on June 2006

Four Key Steps Control Glycolytic Flux in Mammalian Cells

scientific article published on 27 June 2018

Functional role of autophagy-mediated proteome remodeling in cell survival signaling and innate immunity

scientific article published on 28 August 2014

Glucose feeds the TCA cycle via circulating lactate.

scientific article published on 18 October 2017

Glucose-6-phosphate dehydrogenase is not essential for K-Ras-driven tumor growth or metastasis

scientific article published on 13 July 2020

Glutamine-driven oxidative phosphorylation is a major ATP source in transformed mammalian cells in both normoxia and hypoxia.

scientific article published on 3 December 2013

Grm5 expression is not required for the oncogenic role of Grm1 in melanocytes

scientific article published in January 2005

Human IRGM regulates autophagy and cell-autonomous immunity functions through mitochondria

scientific article

Hypoxia and defective apoptosis drive genomic instability and tumorigenesis

scientific article

Hypoxic and Ras-transformed cells support growth by scavenging unsaturated fatty acids from lysophospholipids

scientific article published on 13 May 2013

Identification of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase as a novel autophagy regulator by high content shRNA screening.

scientific article

Identification of tubulin in Dictyostelium discoideum: characterization of some unique properties

scientific article

Immortalized mouse epithelial cell models to study the role of apoptosis in cancer

scientific article

Immune Activation and Benefit From Avelumab in EBV-Positive Gastric Cancer.

scientific article published on 15 November 2017

Immune activation and response to pembrolizumab in POLE-mutant endometrial cancer

scientific article published on 09 May 2016

Immunohistochemical detection of cytoplasmic LC3 puncta in human cancer specimens

scientific article published on 31 May 2012

Induction of apoptosis by diterpenes from the soft coral Xenia elongata ⬇️

scientific article

Induction of apoptosis by human Nbk/Bik, a BH3-containing protein that interacts with E1B 19K

scientific article

Inhibition of ICE-like proteases inhibits apoptosis and increases virus production during adenovirus infection.

scientific article published in April 1998

Key roles of BIM-driven apoptosis in epithelial tumors and rational chemotherapy.

scientific article

Lamin proteolysis facilitates nuclear events during apoptosis

scientific article

Life, death, and the pursuit of apoptosis.

scientific article published on January 1996

Liquid chromatography-high resolution mass spectrometry analysis of fatty acid metabolism

scientific article published on 4 November 2011

Measurement of subcellular texture by optical Gabor-like filtering with a digital micromirror device

scientific article published on October 2008

Mechanisms of apoptosis regulation by viral oncogenes in infection and tumorigenesis.

scientific article

Metabolic catastrophe as a means to cancer cell death

scientific article published on February 2007

Metabotropic glutamate receptor 1 (Grm1) is an oncogene in epithelial cells

scientific article

Mitochondria and Cancer

scientific article published on March 2016

Mode of action of diterpene and characterization of related metabolites from the soft coral, Xenia elongata

scientific article published on 20 February 2014

Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012

scientific article (publication date: 2012)

Mutational landscape of the essential autophagy gene BECN1 in human cancers

scientific article published on 29 January 2014

NBK/BIK antagonizes MCL-1 and BCL-XL and activates BAK-mediated apoptosis in response to protein synthesis inhibition

scientific article published on 2 April 2007

Nuclear envelope localization of an adenovirus tumor antigen maintains the integrity of cellular DNA

scientific article published on December 1984

Nutlin-3 protects kidney cells during cisplatin therapy by suppressing Bax/Bak activation

scientific article

PP2AC Level Determines Differential Programming of p38-TSC-mTOR Signaling and Therapeutic Response to p38-Targeted Therapy in Colorectal Cancer

scientific article

Paradoxical Roles of Elongation Factor-2 Kinase in Stem Cell Survival

scientific article published on 27 July 2016

Parkin targets HIF-1α for ubiquitination and degradation to inhibit breast tumor progression.

scientific article published on 28 November 2017

Principles and current strategies for targeting autophagy for cancer treatment

scientific article

Production of membrane proteins for NMR studies using the condensed single protein (cSPP) production system

scientific article

Quantitative Analysis of NAD Synthesis-Breakdown Fluxes

scientific article published on 20 April 2018

Quantitative Analysis of the Whole-Body Metabolic Fate of Branched-Chain Amino Acids

scientific article published on 15 November 2018

Rationally designed treatment for solid tumors with MAPK pathway activation: a phase I study of paclitaxel and bortezomib using an adaptive dose-finding approach

scientific article

Recent insights into the function of autophagy in cancer

scientific article published on September 2016

Regulation of Apoptosis by the Transforming Genes of the DNA Tumor Virus Adenovirus

scientific article published on October 1, 1993

Regulation of adenovirus gene expression in human WI38 cells by an E1B-encoded tumor antigen

scientific article published on November 1986

Regulation of spindle integrity and mitotic fidelity by BCCIP

scientific article

Regulation of the mitochondrial checkpoint in p53-mediated apoptosis confers resistance to cell death

scientific article published on January 2002

Role of adenovirus E1B proteins in transformation: altered organization of intermediate filaments in transformed cells that express the 19-kilodalton protein

scientific article

Role of autophagy in cancer

scientific article (publication date: December 2007)

Role of autophagy in cancer prevention

scientific article published on July 2011

Role of autophagy in cancer: management of metabolic stress

scientific article

Role of autophagy in suppression of inflammation and cancer

scientific article

Role of the polarity determinant crumbs in suppressing mammalian epithelial tumor progression

scientific article published on June 2008

SMAD4 Suppresses WNT-Driven Dedifferentiation and Oncogenesis in the Differentiated Gut Epithelium

scientific article published on 09 July 2018

SOD1 Phosphorylation by mTORC1 Couples Nutrient Sensing and Redox Regulation

scientific article published on 01 May 2018

SOD1 regulates ribosome biogenesis in KRAS mutant non-small cell lung cancer

scientific article published on 15 April 2021

Specific disruption of intermediate filaments and the nuclear lamina by the 19-kDa product of the adenovirus E1B oncogene

scientific article

Starving cancer from the outside and inside: separate and combined effects of calorie restriction and autophagy inhibition on Ras-driven tumors

scientific article published on 16 September 2016

Suppression of the p300-dependent mdm2 negative-feedback loop induces the p53 apoptotic function

scientific article

Targeting mitochondrial metabolism by inhibiting autophagy in BRAF-driven cancers

scientific article

Targeting tumor metabolism with 2-deoxyglucose in patients with castrate-resistant prostate cancer and advanced malignancies

scientific article

The E1B 19K protein associates with lamins in vivo and its proper localization is required for inhibition of apoptosis.

scientific article published on September 1997

The Genomic Landscape of Renal Oncocytoma Identifies a Metabolic Barrier to Tumorigenesis

scientific article published on 19 November 2015

The adenovirus E1A proteins induce apoptosis, which is inhibited by the E1B 19-kDa and Bcl-2 proteins

scientific article published on August 1992

The double-edged sword of autophagy modulation in cancer

scientific article published on 25 August 2009

The pims and outs of survival signaling: role for the Pim-2 protein kinase in the suppression of apoptosis by cytokines

scientific article

The polyproline region of p53 is required to activate apoptosis but not growth arrest.

scientific article published on August 1997

The role for autophagy in cancer

scientific article

The role of MAP4 expression in the sensitivity to paclitaxel and resistance to vinca alkaloids in p53 mutant cells.

scientific article published on March 1998

Therapeutic starvation and autophagy in prostate cancer: a new paradigm for targeting metabolism in cancer therapy

scientific article published on December 2008

Therapeutic targeting of death pathways in cancer: mechanisms for activating cell death in cancer cells

scientific article published on January 2008

Tumor necrosis factor-alpha induces Bax-Bak interaction and apoptosis, which is inhibited by adenovirus E1B 19K

scientific article

Tumor suppression by autophagy through the management of metabolic stress

scientific article published on 03 March 2008

Ubiquitylation of autophagy receptor Optineurin by HACE1 activates selective autophagy for tumor suppression

scientific article

p53, guardian of Rb

scientific article published in Nature

p53-dependent apoptosis pathways.

scientific article

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