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List of works by Catrin Pritchard

A complex secretory program orchestrated by the inflammasome controls paracrine senescence

scientific article

A critical function for B-Raf at multiple stages of myelopoiesis

scientific journal article

A new mode of RAF autoregulation: a further complication in the inhibitor paradox

scientific article published in May 2013

A-Raf and Raf-1 work together to influence transient ERK phosphorylation and Gl/S cell cycle progression

scientific article

Analysis of the mammalian talin2 gene TLN2.

scientific article

B-Raf acts via the ROCKII/LIMK/cofilin pathway to maintain actin stress fibers in fibroblasts

scientific journal article

BRAF inactivation drives aneuploidy by deregulating CRAF

scientific article

CRAF autophosphorylation of serine 621 is required to prevent its proteasome-mediated degradation

scientific article published on September 2008

Cdx2 initiates histodifferentiation of the midgut endoderm

scientific article published on 23 June 2008

Characterization of novel markers of senescence and their prognostic potential in cancer.

scientific article

Chromosome fragmentation by chromosome mediated gene transfer.

scientific article published on January 1988

Colorectal cancer cells with the BRAF(V600E) mutation are addicted to the ERK1/2 pathway for growth factor-independent survival and repression of BIM.

scientific article published on 22 September 2008

Construction of Lambda Libraries from Large PFGE Fragments

scientific article published on January 1, 1992

Cyp24a1 Attenuation Limits Progression of BrafV600E -Induced Papillary Thyroid Cancer Cells and Sensitizes Them to BRAFV600E Inhibitor PLX4720.

scientific article published on 27 February 2017

ERK signalling and oncogene transformation are not impaired in cells lacking A-Raf

scientific article published on January 2002

Early detection of pre-malignant lesions in a KRAS-driven mouse lung cancer model by monitoring circulating free DNA

scientific article published on 12 February 2019

Endothelial cell talin1 is essential for embryonic angiogenesis.

scientific article published on 26 November 2010

Ex Vivo Explant Cultures of Non-Small Cell Lung Carcinoma Enable Evaluation of Primary Tumor Responses to Anticancer Therapy

scientific article published on 15 February 2017

Expression of endogenous oncogenic V600EB-raf induces proliferation and developmental defects in mice and transformation of primary fibroblasts

scientific article published on December 2005

Expression of kinase suppressor of Ras in the normal adult and embryonic mouse.

scientific article published in July 2002

Genetic analysis of the human Y chromosome by chromosome-mediated gene transfer.

scientific article published on January 1987

Hematopoietic expression of oncogenic BRAF promotes aberrant growth of monocyte-lineage cells resistant to PLX4720.

scientific article published on 23 October 2013

Inactivation of TGFβ receptors in stem cells drives cutaneous squamous cell carcinoma

scientific article published on 25 August 2016

Inducible expression of (V600E) Braf using tyrosinase-driven Cre recombinase results in embryonic lethality.

scientific article published on 11 December 2009

Isolation and field-inversion gel electrophoresis analysis of DNA markers located close to the Huntington disease gene.

scientific article

KRAS(G12D)-mediated oncogenic transformation of thyroid follicular cells requires long-term TSH stimulation and is regulated by SPRY1.

scientific article published on 6 July 2015

KRASG12D expression in lung-resident myeloid cells promotes pulmonary LCH-like neoplasm sensitive to statin treatment

scientific article published on 26 May 2017

Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF

scientific article

Lineage tracing of cardiac explant derived cells.

scientific article

MGL ligand expression is correlated to BRAF mutation and associated with poor survival of stage III colon cancer patients.

scientific article

MIC2: a human pseudoautosomal gene

scientific article published on 01 December 1988

Mapping the limits of the human pseudoautosomal region and a candidate sequence for the male-determining gene

scientific article published in Nature

Mechanisms of aneuploidy induction by RAS and RAF oncogenes

scientific article published on 29 March 2011

Mouse models for BRAF-induced cancers

scientific article published on November 2007

Oncogenic Braf induces melanocyte senescence and melanoma in mice

scientific article

Over-expressed, N-terminally truncated BRAF is detected in the nucleus of cells with nuclear phosphorylated MEK and ERK

scientific article published on 20 December 2018

Phosphorylations of Serines 21/9 in Glycogen Synthase Kinase 3α/β Are Not Required for Cell Lineage Commitment or WNT Signaling in the Normal Mouse Intestine

scientific article

Post-natal lethality and neurological and gastrointestinal defects in mice with targeted disruption of the A-Raf protein kinase gene.

scientific article

Profiling tumour heterogeneity through circulating tumour DNA in patients with pancreatic cancer.

scientific article published on 14 August 2017

Raf Kinases Are Essential for Phosphate Induction of ERK1/2 Phosphorylation in Hypertrophic Chondrocytes and Normal Endochondral Bone Development.

scientific article published on 10 January 2017

Raf revealed in life-or-death decisions

scientific article published on 01 July 1997

Raf-1 is not required for megakaryocytopoiesis or TPO-induced ERK phosphorylation ⬇️

scientific article published on October 23, 2003

RalGDS is required for tumor formation in a model of skin carcinogenesis.

scientific article

Rapid induction of heparin-binding epidermal growth factor/diphtheria toxin receptor expression by Raf and Ras oncogenes.

scientific article

Recombination between the X and Y chromosomes: implications for the relationship between MIC2, XG and YG

scientific article published on 01 May 1987

Recombination of 4p16 DNA markers in an unusual family with Huntington disease.

scientific article

Reduced vas deferens contraction and male infertility in mice lacking P2X1 receptors

scientific journal article

Regulation of BRAF protein stability by a negative feedback loop involving the MEK-ERK pathway but not the FBXW7 tumour suppressor.

scientific article

Regulation of MEK/ERK pathway output by subcellular localization of B-Raf

scientific article published on February 2012

TSH overcomes Braf(V600E)-induced senescence to promote tumor progression via downregulation of p53 expression in papillary thyroid cancer.

scientific article published on 19 October 2015

Talin 2 is a large and complex gene encoding multiple transcripts and protein isoforms

scientific article

The cholesterol-binding protein NPC2 restrains recruitment of stromal macrophage-lineage cells to early-stage lung tumours

scientific article

The end in sight for Huntington disease? ⬇️

scientific article published on July 1, 1991

The intermediate-activity (L597V)BRAF mutant acts as an epistatic modifier of oncogenic RAS by enhancing signaling through the RAF/MEK/ERK pathway

scientific journal article

Thyrotrophin receptor signaling dependence of Braf-induced thyroid tumor initiation in mice

scientific article

Tracking genomic cancer evolution for precision medicine: the lung TRACERx study

scientific article

V600EBraf induces gastrointestinal crypt senescence and promotes tumour progression through enhanced CpG methylation of p16INK4a

scientific article published on November 2010

cAMP-dependent protein kinase and Ca2+ influx through L-type voltage-gated calcium channels mediate Raf-independent activation of extracellular regulated kinase in response to glucagon-like peptide-1 in pancreatic beta-cells

scientific article published on 2 October 2002

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