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List of works by Rodney B Luwor

A comprehensive meta-analysis of circulation miRNAs in glioma as potential diagnostic biomarker

scientific article published on 14 February 2018

A critical role of Oct4A in mediating metastasis and disease-free survival in a mouse model of ovarian cancer

scientific article

Anti-EGFR therapeutic efficacy correlates directly with inhibition of STAT3 activity.

scientific article published on 20 February 2014

Antibodies specifically targeting a locally misfolded region of tumor associated EGFR

scientific article

Antitumor efficacy of cytotoxic drugs and the monoclonal antibody 806 is enhanced by the EGF receptor inhibitor AG1478.

scientific article

Betaglycan blocks metastatic behaviors in human granulosa cell tumors by suppressing NFκB-mediated induction of MMP2.

scientific article published on 13 August 2014

Cell quiescence correlates with enhanced glioblastoma cell invasion and cytotoxic resistance

scientific article published on 15 December 2018

Coalition of Oct4A and β1 integrins in facilitating metastasis in ovarian cancer.

scientific article

Constitutively active Harvey Ras confers resistance to epidermal growth factor receptor-targeted therapy with cetuximab and gefitinib.

scientific article

Defining the essential function of FBP/KSRP proteins: Drosophila Psi interacts with the mediator complex to modulate MYC transcription and tissue growth

scientific article published on 20 May 2016

Dynamin II function is required for EGF-mediated Stat3 activation but not Erk1/2 phosphorylation.

scientific article published on 11 May 2012

Effects of EphB4 receptor expression on colorectal cancer cells, tumor growth, vascularization and composition

scientific article

Enhancement of invadopodia activity in glioma cells by sublethal doses of irradiation and temozolomide

scientific article published on 17 November 2017

Epidermal growth factor receptor (EGFR) ubiquitination as a mechanism of acquired resistance escaping treatment by the anti-EGFR monoclonal antibody cetuximab

scientific article published on 01 September 2007

Epidermal growth factor receptor: Structure-function informing the design of anticancer therapeutics

scientific article published on 09 August 2018

Expression of the adaptor protein Tks5 in human cancer: prognostic potential

scientific article published on 4 July 2014

Glycogen synthase kinase-3β (GSK-3β) and its dysregulation in glioblastoma multiforme.

scientific article published on 12 June 2013

Inhibition of Radiation and Temozolomide-Induced Invadopodia Activity in Glioma Cells Using FDA-Approved Drugs

scientific article published on 13 September 2018

Inhibition of glioblastoma cell proliferation, migration and invasion by the proteasome antagonist carfilzomib.

scientific article published on 20 April 2016

Inhibition of the JAK2/STAT3 pathway in ovarian cancer results in the loss of cancer stem cell-like characteristics and a reduced tumor burden

scientific article

Interleukin-11 is the dominant IL-6 family cytokine during gastrointestinal tumorigenesis and can be targeted therapeutically

scientific article published on August 2013

Knockdown of stem cell regulator Oct4A in ovarian cancer reveals cellular reprogramming associated with key regulators of cytoskeleton-extracellular matrix remodelling

scientific article

MicroRNA as potential biomarkers in Glioblastoma

scientific article published on 21 September 2015

Momelotinib decreased cancer stem cell associated tumor burden and prolonged disease-free remission period in a mouse model of human ovarian cancer.

scientific article published on 30 March 2018

Mouse models of glioma

scientific article

Nuclear receptor NR4A1 promotes breast cancer invasion and metastasis by activating TGF-β signalling

scientific article published in Nature Communications

Paclitaxel-Induced Src Activation Is Inhibited by Dasatinib Treatment, Independently of Cancer Stem Cell Properties, in a Mouse Model of Ovarian Cancer

scientific article published on 19 February 2019

Paclitaxel-Loaded Self-Assembled Lipid Nanoparticles as Targeted Drug Delivery Systems for the Treatment of Aggressive Ovarian Cancer

scientific article published on 20 July 2018

Ponatinib: a novel multi-tyrosine kinase inhibitor against human malignancies

scientific article published on 18 January 2019

SPSB1, a Novel Negative Regulator of the Transforming Growth Factor-β Signaling Pathway Targeting the Type II Receptor.

scientific article published on June 2015

STAT3 signaling mediates tumour resistance to EGFR targeted therapeutics

scientific article published on 11 January 2017

Short-term single treatment of chemotherapy results in the enrichment of ovarian cancer stem cell-like cells leading to an increased tumor burden

scientific article published on 27 March 2013

Single live cell TGF-β signalling imaging: breast cancer cell motility and migration is driven by sub-populations of cells with dynamic TGF-β-Smad3 activity

scientific article

Targeted Disruption of the JAK2/STAT3 Pathway in Combination with Systemic Administration of Paclitaxel Inhibits the Priming of Ovarian Cancer Stem Cells Leading to a Reduced Tumor Burden.

scientific article published on 09 April 2014

Targeting Stat3 and Smad7 to restore TGF-β cytostatic regulation of tumor cells in vitro and in vivo ⬇️

scientific article published on July 2, 2012

The Interleukin-11/IL-11 Receptor Promotes Glioblastoma Survival and Invasion under Glucose-Starved Conditions through Enhanced Glutaminolysis

scientific article published in 2023

The emergent role of exosomes in glioma

scientific article

The peroxisome proliferator activated receptor gamma agonist pioglitazone increases functional expression of the glutamate transporter excitatory amino acid transporter 2 (EAAT2) in human glioblastoma cells

scientific article

The role of STAT3 signaling in mediating tumor resistance to cancer therapy.

scientific article

The role of Stat3 in glioblastoma multiforme.

scientific article published on 17 May 2013

The role of interleukin-6-STAT3 signalling in glioblastoma

scientific article published on 27 July 2018

The tumor-specific de2-7 epidermal growth factor receptor (EGFR) promotes cells survival and heterodimerizes with the wild-type EGFR.

scientific article published on August 2004

Transforming growth factor-beta (TGF-beta) and brain tumours.

scientific article published on 11 June 2008

Treatment of human tumor xenografts with monoclonal antibody 806 in combination with a prototypical epidermal growth factor receptor-specific antibody generates enhanced antitumor activity.

scientific article published in September 2005

Using bioluminescence imaging in glioma research

scientific article published on 26 March 2015

miRNA expression profiling of cerebrospinal fluid in patients with aneurysmal subarachnoid hemorrhage.

scientific article published on 29 April 2016

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