List of works by Willem J Lesterhuis

A pilot study on the immunogenicity of dendritic cell vaccination during adjuvant oxaliplatin/capecitabine chemotherapy in colon cancer patients.

scientific article published on 5 October 2010

A systematic investigation of the maximum tolerated dose of cytotoxic chemotherapy with and without supportive care in mice

scientific article published on 16 October 2017

A tipping point in cancer-immune dynamics leads to divergent immunotherapy responses and hampers biomarker discovery

scientific article published on 31 May 2021

Acute arterial occlusion after chemotherapy for testicular cancer

scientific article published on 01 November 2005

Acute generalised exanthematous pustulosis mimicking septic shock

scientific article published on 01 April 2004

Autologous monocyte-derived DC vaccination combined with cisplatin in stage III and IV melanoma patients: a prospective, randomized phase 2 trial

scientific article published on 24 January 2020

Bilateral murine tumor models for characterizing the response to immune checkpoint blockade

scientific article published on 01 April 2020

Characteristics of TCR Repertoire Associated With Successful Immune Checkpoint Therapy Responses

scientific article published on 14 October 2020

Chemoimmunotherapy: still waiting for the magic to happen

scientific article published on 19 June 2014

Chemotherapy and immunotherapy: mapping the road ahead.

scientific article published on 24 December 2015

Combination immune checkpoint blockade as an effective therapy for mesothelioma

article

Comment on "drug discovery: turning the titanic"

scientific article published on 01 March 2014

Dendritic Cell Vaccination in Combination with Anti-CD25 Monoclonal Antibody Treatment: A Phase I/II Study in Metastatic Melanoma Patients

scientific article published on 24 August 2010

Dendritic cell immunotherapy: mapping the way.

scientific article published on May 2004

Dendritic cell-based vaccines in cancer immunotherapy: an update on clinical and immunological results.

scientific article published in January 2004

Dexamethasone differentially depletes tumour and peripheral blood lymphocytes and can impact the efficacy of chemotherapy/checkpoint blockade combination treatment

scientific article published on 13 July 2019

Direct inhibition of STAT signaling by platinum drugs contributes to their anti-cancer activity.

scientific article published on 7 May 2017

Dynamic versus static biomarkers in cancer immune checkpoint blockade: unravelling complexity.

scientific article published on 6 January 2017

EBV-related lymphoproliferative disorders in immunocompetent patients

scientific article published on 01 December 2003

Early identification of antigen-specific immune responses in vivo by [18F]-labeled 3'-fluoro-3'-deoxy-thymidine ([18F]FLT) PET imaging.

scientific article published on 24 October 2011

Esophageal Adenocarcinoma Cells and Xenograft Tumors Exposed to Erb-b2 Receptor Tyrosine Kinase 2 and 3 Inhibitors Activate Transforming Growth Factor Beta Signaling, Which Induces Epithelial to Mesenchymal Transition.

scientific article published on 9 March 2017

Favorable overall survival in stage III melanoma patients after adjuvant dendritic cell vaccination.

scientific article published on 5 June 2015

Immunomonitoring Tumor-Specific T Cells in Delayed-Type Hypersensitivity Skin Biopsies After Dendritic Cell Vaccination Correlates With Clinical Outcome

scientific article published on 01 August 2005

In situ detection of antigen-specific T cells in cryo-sections using MHC class I tetramers after dendritic cell vaccination of melanoma patients

scientific article published on 18 April 2007

Limited Amounts of Dendritic Cells Migrate into the T-Cell Area of Lymph Nodes but Have High Immune Activating Potential in Melanoma Patients

article

Molecular pathways: the immunogenic effects of platinum-based chemotherapeutics.

scientific article published on June 2014

Neoadjuvant anti-tumor vaccination prior to surgery enhances survival

scientific article

Network analysis of immunotherapy-induced regressing tumours identifies novel synergistic drug combinations.

scientific article published on 21 July 2015

PD-L2 is predominantly expressed by Th2 cells

scientific article published on 13 October 2011

Polyinosinic polycytidylic acid prevents efficient antigen expression after mRNA electroporation of clinical grade dendritic cells.

scientific article published on 19 November 2008

Programmed death ligand 2 in cancer-induced immune suppression.

scientific article

Recovery of symptomatic extravasation of liposomal doxorubicin after dexrazoxane treatment

scientific article published on 01 January 2012

Route of Administration Modulates the Induction of Dendritic Cell Vaccine-Induced Antigen-Specific T Cells in Advanced Melanoma Patients

scientific article published on 19 July 2011

Sensitivity of magnetic resonance imaging of dendritic cells for in vivo tracking of cellular cancer vaccines.

scientific article published in March 2007

Sensitization to immune checkpoint blockade through activation of a STAT1/NK axis in the tumor microenvironment

scientific article published on 01 July 2019

Skin-Test Infiltrating Lymphocytes Early Predict Clinical Outcome of Dendritic Cell-Based Vaccination in Metastatic Melanoma

scientific article published on 24 September 2012

Strong spontaneous tumor neoantigen responses induced by a natural human carcinogen

scientific article published on 11 May 2015

Targeting of 111In-Labeled Dendritic Cell Human Vaccines Improved by Reducing Number of Cells

scientific article published on 04 February 2013

Transient Treg depletion enhances therapeutic anti-cancer vaccination.

scientific article

Tumor-infiltrating dendritic cells exhibit defective cross-presentation of tumor antigens, but is reversed by chemotherapy.

scientific article published on 15 December 2014

Tumour associated lymphocytes in the pleural effusions of patients with mesothelioma express high levels of inhibitory receptors

article

Vaccination of colorectal cancer patients with CEA-loaded dendritic cells: antigen-specific T cell responses in DTH skin tests

article

Vaccination with mRNA-Electroporated Dendritic Cells Induces Robust Tumor Antigen-Specific CD4+ and CD8+ T Cells Responses in Stage III and IV Melanoma Patients

article

Vascular endothelial growth factor in systemic capillary leak syndrome.

scientific article

Wild-type and modified gp100 peptide-pulsed dendritic cell vaccination of advanced melanoma patients can lead to long-term clinical responses independent of the peptide used

article

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