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List of works by Leanne Hodson

A Single Day of Excessive Dietary Fat Intake Reduces Whole-Body Insulin Sensitivity: The Metabolic Consequence of Binge Eating.

scientific article published on 29 July 2017

A cellular model for the investigation of depot specific human adipocyte biology

scientific article published on 06 January 2017

AKR1D1 is a novel regulator of metabolic phenotype in human hepatocytes and is dysregulated in non-alcoholic fatty liver disease

scientific article published on 19 July 2019

AKR1D1 regulates glucocorticoid availability and glucocorticoid receptor activation in human hepatoma cells

scientific article published on 12 February 2019

Are oxidative stress mechanisms the common denominator in the progression from hepatic steatosis towards non-alcoholic steatohepatitis (NASH)?

scientific article published on 28 March 2014

Challenging metabolic tissues with fructose: tissue-specific and sex-specific responses

scientific article published on 02 April 2019

Characterization of lipid metabolism in a novel immortalized human hepatocyte cell line.

scientific article

Chronic Palmitate Exposure Inhibits Insulin Secretion by Dissociation of Ca2+ Channels from Secretory Granules

scientific article

Chronic palmitate exposure inhibits insulin secretion by dissociation of Ca(2+) channels from secretory granules

scientific article published on December 2009

De novo lipogenesis in the differentiating human adipocyte can provide all fatty acids necessary for maturation.

scientific article

Dietary Approaches to Stop Hypertension (DASH) diet: applicability and acceptability to a UK population.

scientific article published on 15 October 2009

Dietary fat and insulin sensitivity

scientific article published on 25 February 2010

Differences in partitioning of meal fatty acids into blood lipid fractions: a comparison of linoleate, oleate, and palmitate.

scientific article published on 21 October 2008

Docosahexaenoic acid enrichment in NAFLD is associated with improvements in hepatic metabolism and hepatic insulin sensitivity: a pilot study.

scientific article published on 15 March 2017

Does the DASH diet lower blood pressure by altering peripheral vascular function?

scientific article published on 6 August 2009

Downregulation of adipose tissue fatty acid trafficking in obesity: a driver for ectopic fat deposition?

scientific article

Dual-5α-Reductase Inhibition Promotes Hepatic Lipid Accumulation in Man

scientific article

Effect of supplementation with flaxseed oil and different doses of fish oil for 2 weeks on plasma phosphatidylcholine fatty acids in young women

scientific article published on 30 May 2018

Effects of purified eicosapentaenoic and docosahexaenoic acids in nonalcoholic fatty liver disease: results from the Welcome* study

scientific article published on 01 October 2014

Effects of roux-en-Y gastric bypass surgery on postprandial fructose metabolism

scientific article published on 01 March 2016

Effects of supplementation with essential amino acids on intrahepatic lipid concentrations during fructose overfeeding in humans

scientific article published on 03 October 2012

Erratum: Effects of roux-en-Y gastric bypass surgery on postprandial fructose metabolism

scientific article published on 01 March 2017

Exercise performed immediately after fructose ingestion enhances fructose oxidation and suppresses fructose storage.

scientific article published on 23 December 2015

Exercise prevents fructose-induced hypertriglyceridemia in healthy young subjects

scientific article published on 14 May 2013

Fasting Plasma Insulin Concentrations Are Associated With Changes in Hepatic Fatty Acid Synthesis and Partitioning Prior to Changes in Liver Fat Content in Healthy Adults

scientific article

Fasting hepatic de novo lipogenesis is not reliably assessed using circulating fatty acid markers

scientific article published on 01 February 2019

Fatty acid composition of adipose tissue and blood in humans and its use as a biomarker of dietary intake

scientific article published on 4 April 2008

Fatty acid metabolism in patients with PPARgamma mutations

scientific article

From whole body to cellular models of hepatic triglyceride metabolism: man has got to know his limitations

scientific article

Glucocorticoids regulate AKR1D1 activity in human liver in vitro and in vivo

scientific article published on 01 February 2020

Gluteofemoral adipose tissue plays a major role in production of the lipokine palmitoleate in humans

scientific article

Greater dietary fat oxidation in obese compared with lean men: an adaptive mechanism to prevent liver fat accumulation?

scientific article

Hepatic de novo lipogenesis is suppressed and fat oxidation is increased by omega-3 fatty acids at the expense of glucose metabolism

scientific article published on 01 March 2020

Hepatic fatty acid partitioning ⬇️

scientific article published on June 1, 2011

Hepatic fatty acid synthesis and partitioning: the effect of metabolic and nutritional state

scientific article published on 20 November 2018

Hepatocyte-specific IKK-β activation enhances VLDL-triglyceride production in APOE*3-Leiden mice

scientific article

Human PNPLA3-I148M variant increases hepatic retention of polyunsaturated fatty acids

scientific article published on 22 August 2019

Hydroxysteroid 17-β dehydrogenase 13 variant increases phospholipids and protects against fibrosis in nonalcoholic fatty liver disease

scientific article published on 12 March 2020

In vitro cellular models of human hepatic fatty acid metabolism: differences between Huh7 and HepG2 cell lines in human and fetal bovine culturing serum.

scientific article published in December 2017

Independent effects of circulating glucose, insulin and NEFA on cardiac triacylglycerol accumulation and myocardial insulin resistance in a swine model.

scientific article published on 25 June 2014

Influence of dietary macronutrients on liver fat accumulation and metabolism.

scientific article

Intrahepatic Fat and Postprandial Glycemia Increase After Consumption of a Diet Enriched in Saturated Fat Compared With Free Sugars

scientific article published on 12 March 2020

Is there something special about palmitoleate?

scientific article published on March 2013

Markers of de novo lipogenesis in adipose tissue: associations with small adipocytes and insulin sensitivity in humans.

scientific article published on 28 February 2009

Measuring Human Lipid Metabolism Using Deuterium Labeling: In Vivo and In Vitro Protocols

scientific article published on 01 January 2019

Menopausal Status and Abdominal Obesity Are Significant Determinants of Hepatic Lipid Metabolism in Women

scientific article published on 2 October 2015

Metabolic fate of fructose ingested with and without glucose in a mixed meal.

scientific article

Metabolic inflexibility is an early marker of bed-rest induced glucose intolerance even when fat mass is stable.

scientific article published on 12 March 2018

Micro-techniques for analysis of human adipose tissue fatty acid composition in dietary studies

scientific article published on 08 December 2012

Modifying nutritional substrates induces macrovesicular lipid droplet accumulation and metabolic alterations in a cellular model of hepatic steatosis

scientific article published on 01 July 2020

Non-alcoholic fatty liver disease concerns with glucokinase activators

scientific article published on 01 September 2018

Nonalcoholic Fatty Liver Disease in Adults: Current Concepts in Etiology, Outcomes, and Management

scientific article published on 01 January 2020

Nuclear receptor REVERBα is a state-dependent regulator of liver energy metabolism

scientific article published on 28 September 2020

Of mice and men: Is there a future for metformin in the treatment of hepatic steatosis?

scientific article published on 21 December 2018

Optimizing human hepatocyte models for metabolic phenotype and function: effects of treatment with dimethyl sulfoxide (DMSO).

scientific article published on November 2016

Plasma and erythrocyte fatty acids reflect intakes of saturated and n-6 PUFA within a similar time frame

scientific article published on 13 November 2013

Prolyl-4-hydroxylase 3 maintains β cell glucose metabolism during fatty acid excess in mice

scientific article published in 2021

Publisher Correction: The regulation of hepatic fatty acid synthesis and partitioning: the effect of nutritional state

scientific article published on 09 March 2020

Relevance of human fat distribution on lipid and lipoprotein metabolism and cardiovascular disease risk

scientific article published on 01 August 2018

Removal of triacylglycerols from chylomicrons and VLDL by capillary beds: the basis of lipoprotein remnant formation.

scientific article published on June 2007

Report of a member-led meeting: how stable isotope techniques can enhance human nutrition research

scientific article published on 04 June 2020

Saturated Fat Is More Metabolically Harmful for the Human Liver Than Unsaturated Fat or Simple Sugars

scientific article published on 29 May 2018

Sex Differences in Hepatic Lipogenesis with Acute Fructose Feeding

Sex-Specific Differences in Hepatic Fat Oxidation and Synthesis May Explain the Higher Propensity for NAFLD in Men.

scientific article

Splanchnic balance of free fatty acids, endocannabinoids, and lipids in subjects with nonalcoholic fatty liver disease

scientific article published on 27 June 2010

Stability of plasma and erythrocyte fatty acid composition during cold storage

scientific article published on 1 July 2002

Stearoyl-CoA desaturase: rogue or innocent bystander?

scientific article published on 21 September 2012

Structural and functional properties of deep abdominal subcutaneous adipose tissue explain its association with insulin resistance and cardiovascular risk in men.

scientific article published in November 2013

Studying non-alcoholic fatty liver disease: the ins and outs of in vivo, ex vivo and in vitro human models

scientific article published on 11 August 2018

Substrate utilization by the failing human heart by direct quantification using arterio-venous blood sampling.

scientific article published on 21 October 2009

The Importance of the Fatty Acid Transporter L-Carnitine in Non-Alcoholic Fatty Liver Disease (NAFLD)

scientific article published on 22 July 2020

The PNPLA3-I148M variant increases polyunsaturated triglycerides in human adipose tissue

scientific article published on 09 May 2020

The effect of replacing dietary saturated fat with polyunsaturated or monounsaturated fat on plasma lipids in free-living young adults

scientific article

The effects of endogenously- and exogenously-induced hyperketonemia on exercise performance and adaptation

scientific article published on 01 May 2022

The influence of dietary fat on liver fat accumulation.

scientific article

The influence of dietary fatty acids on liver fat content and metabolism

scientific article published on 03 April 2019

The isolation of primary hepatocytes from human tissue: optimising the use of small non-encapsulated liver resection surplus

scientific article published on 17 July 2017

The regulation of hepatic fatty acid synthesis and partitioning: the effect of nutritional state

scientific article published on 01 December 2019

The role of glucose, insulin and NEFA in regulating tissue triglyceride accumulation: Substrate cooperation in adipose tissue versus substrate competition in skeletal muscle

scientific article published on 16 August 2017

The storage stability and concentration of acetoacetate differs between blood fractions.

scientific article published on 8 April 2014

Total Fatty Acid Analysis of Human Blood Samples in One Minute by High-Resolution Mass Spectrometry

scientific article published in 2018

Transient Cold Storage Prior to Normothermic Liver Perfusion May Facilitate Adoption of a Novel Technology

scientific article published on 18 July 2019

Triglyceride-rich lipoprotein metabolism in women: roles of apoC-II and apoC-III.

scientific article published on 5 July 2016

Young women partition fatty acids towards ketone body production rather than VLDL-TAG synthesis, compared with young men.

scientific article published on 21 January 2011

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