List of works - Christopher M Adams

Activating transcription factor 4 (ATF4) promotes skeletal muscle atrophy by forming a heterodimer with the transcriptional regulator C/EBPβ

scientific article published on 17 January 2020

Alterations in the muscle force transfer apparatus in aged rats during unloading and reloading: impact of microRNA-31

scientific article published on 01 July 2018

Altered mRNA expression after long-term soleus electrical stimulation training in humans with paralysis

scientific article

Amino Acid Sensing in Skeletal Muscle

scientific article

Atf4 regulates obesity, glucose homeostasis, and energy expenditure

scientific article

Control of skeletal muscle atrophy in response to disuse: clinical/preclinical contentions and fallacies of evidence

scientific article

Enhanced locomotion caused by loss of the Drosophila DEG/ENaC protein Pickpocket1.

scientific article published in September 2003

Evidence for metabolic aberrations in asymptomatic persons with type 2 diabetes after initiation of simvastatin therapy

scientific article published on 28 January 2015

Gadd45a Protein Promotes Skeletal Muscle Atrophy by Forming a Complex with the Protein Kinase MEKK4

scientific article published on 29 June 2016

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Identification and Small Molecule Inhibition of an Activating Transcription Factor 4 (ATF4)-dependent Pathway to Age-related Skeletal Muscle Weakness and Atrophy.

scientific article

Inhibition of the Epithelial Na+ Channel by Interaction of Nedd4 with a PY Motif Deleted in Liddle's Syndrome ⬇️

scientific article published on November 6, 1998

Insulin signaling and the general amino acid control response. Two distinct pathways to amino acid synthesis and uptake.

scientific article

Interactions between subunits of the human epithelial sodium channel.

scientific article published in October 1997

Mechanism by which Liddle's syndrome mutations increase activity of a human epithelial Na+ channel

scientific article

OPA1 deficiency promotes secretion of FGF21 from muscle that prevents obesity and insulin resistance.

scientific article published on 12 June 2017

Obesity challenges the hepatoprotective function of the integrated stress response to asparaginase exposure in mice.

scientific article

Protons activate brain Na+ channel 1 by inducing a conformational change that exposes a residue associated with neurodegeneration.

scientific article published in November 1998

Rapid and Sensitive Quantification of Ursolic Acid and Oleanolic Acid in Human Plasma Using Ultra-performance Liquid Chromatography-Mass Spectrometry

scientific article published on 01 August 2018

Ripped pocket and pickpocket, novel Drosophila DEG/ENaC subunits expressed in early development and in mechanosensory neurons.

scientific article published in January 1998

Role of ATF4 in skeletal muscle atrophy.

scientific article

Role of the transcription factor ATF4 in the anabolic actions of insulin and the anti-anabolic actions of glucocorticoids

scientific article published on 12 April 2007

Skeletal muscle denervation causes skeletal muscle atrophy through a pathway that involves both Gadd45a and HDAC4.

scientific article published on 13 August 2013

Spermine oxidase maintains basal skeletal muscle gene expression and fiber size and is strongly repressed by conditions that cause skeletal muscle atrophy.

scientific article

Stress-induced skeletal muscle Gadd45a expression reprograms myonuclei and causes muscle atrophy.

scientific article

Systems-based discovery of tomatidine as a natural small molecule inhibitor of skeletal muscle atrophy

scientific article

Tetraethylammonium block of the BNC1 channel.

scientific article

Three mutations in sterol-sensing domain of SCAP block interaction with insig and render SREBP cleavage insensitive to sterols.

scientific article

Transcription factor ATF4 directs basal and stress-induced gene expression in the unfolded protein response and cholesterol metabolism in the liver.

scientific article published on 9 March 2016

Ursolic acid increases skeletal muscle and brown fat and decreases diet-induced obesity, glucose intolerance and fatty liver disease

scientific article published in 2012

Use of mRNA expression signatures to discover small molecule inhibitors of skeletal muscle atrophy

scientific article

mRNA expression signatures of human skeletal muscle atrophy identify a natural compound that increases muscle mass

scientific article (publication date: 8 June 2011)

p53 and ATF4 mediate distinct and additive pathways to skeletal muscle atrophy during limb immobilization

scientific article

List of works by Christopher M Adams

Activating transcription factor 4 (ATF4) promotes skeletal muscle atrophy by forming a heterodimer with the transcriptional regulator C/EBPβ

Alterations in the muscle force transfer apparatus in aged rats during unloading and reloading: impact of microRNA-31

Altered mRNA expression after long-term soleus electrical stimulation training in humans with paralysis

Amino Acid Sensing in Skeletal Muscle

Atf4 regulates obesity, glucose homeostasis, and energy expenditure

Control of skeletal muscle atrophy in response to disuse: clinical/preclinical contentions and fallacies of evidence

Enhanced locomotion caused by loss of the Drosophila DEG/ENaC protein Pickpocket1.

Evidence for metabolic aberrations in asymptomatic persons with type 2 diabetes after initiation of simvastatin therapy

Gadd45a Protein Promotes Skeletal Muscle Atrophy by Forming a Complex with the Protein Kinase MEKK4

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Identification and Small Molecule Inhibition of an Activating Transcription Factor 4 (ATF4)-dependent Pathway to Age-related Skeletal Muscle Weakness and Atrophy.

Inhibition of the Epithelial Na+ Channel by Interaction of Nedd4 with a PY Motif Deleted in Liddle's Syndrome ⬇️

Insulin signaling and the general amino acid control response. Two distinct pathways to amino acid synthesis and uptake.

Interactions between subunits of the human epithelial sodium channel.

Mechanism by which Liddle's syndrome mutations increase activity of a human epithelial Na+ channel

OPA1 deficiency promotes secretion of FGF21 from muscle that prevents obesity and insulin resistance.

Obesity challenges the hepatoprotective function of the integrated stress response to asparaginase exposure in mice.

Protons activate brain Na+ channel 1 by inducing a conformational change that exposes a residue associated with neurodegeneration.

Rapid and Sensitive Quantification of Ursolic Acid and Oleanolic Acid in Human Plasma Using Ultra-performance Liquid Chromatography-Mass Spectrometry

Ripped pocket and pickpocket, novel Drosophila DEG/ENaC subunits expressed in early development and in mechanosensory neurons.

Role of ATF4 in skeletal muscle atrophy.

Role of the transcription factor ATF4 in the anabolic actions of insulin and the anti-anabolic actions of glucocorticoids

Skeletal muscle denervation causes skeletal muscle atrophy through a pathway that involves both Gadd45a and HDAC4.

Spermine oxidase maintains basal skeletal muscle gene expression and fiber size and is strongly repressed by conditions that cause skeletal muscle atrophy.

Stress-induced skeletal muscle Gadd45a expression reprograms myonuclei and causes muscle atrophy.

Systems-based discovery of tomatidine as a natural small molecule inhibitor of skeletal muscle atrophy

Tetraethylammonium block of the BNC1 channel.

Three mutations in sterol-sensing domain of SCAP block interaction with insig and render SREBP cleavage insensitive to sterols.

Transcription factor ATF4 directs basal and stress-induced gene expression in the unfolded protein response and cholesterol metabolism in the liver.

Ursolic acid increases skeletal muscle and brown fat and decreases diet-induced obesity, glucose intolerance and fatty liver disease

Use of mRNA expression signatures to discover small molecule inhibitors of skeletal muscle atrophy

mRNA expression signatures of human skeletal muscle atrophy identify a natural compound that increases muscle mass

p53 and ATF4 mediate distinct and additive pathways to skeletal muscle atrophy during limb immobilization