List of works - Xavier De la Cruz

A fast method for the determination of fractional contributions to solvation in proteins.

scientific article published on 25 September 2006

A new procedure for constructing peptides into a given Calpha chain.

scientific article published in January 1998

A procedure for identifying homologous alternative splicing events

scientific article

Alternative splicing mechanisms for the modulation of protein function: conservation between human and other species.

scientific article

Alternative splicing of transcription factors' genes: beyond the increase of proteome diversity

scientific article published on 12 July 2009

An atomistic view to the gas phase proteome

scientific article published on 01 January 2009

Assessment of blind predictions of the clinical significance of BRCA1 and BRCA2 variants

scientific article published on 23 August 2019

Autoacetylation regulates P/CAF nuclear localization.

scientific article published on 17 November 2008

BRCA1- and BRCA2-specific in silico tools for variant interpretation in the CAGI 5 ENIGMA challenge

scientific article published on 03 July 2019

Cerebrospinal fluid-derived circulating tumour DNA better represents the genomic alterations of brain tumours than plasma.

scientific article

Characterization of disease-associated single amino acid polymorphisms in terms of sequence and structure properties.

scientific article

Characterization of structural variability sheds light on the specificity determinants of the interaction between effector domains and histone tails

scientific article published on 01 February 2010

Classical molecular interaction potentials: improved setup procedure in molecular dynamics simulations of proteins.

scientific article published in December 2001

Clinical and structural impact of mutations affecting the residue Phe367 of FOXP3 in patients with IPEX syndrome.

scientific article

Compensated pathogenic variants in coagulation factors VIII and IX present complex mapping between molecular impact and hemophilia severity

scientific article published on 02 July 2019

Data Mining of Molecular Dynamic Trajectories of Nucleic Acids

Discrete representations of the protein C alpha chain

scientific article

EZH2 regulates neuroepithelium structure and neuroblast proliferation by repressing p21.

scientific article published on 20 April 2016

Exploring the Essential Dynamics of B-DNA

scientific article published on 01 September 2005

Genome-wide analysis reveals that Smad3 and JMJD3 HDM co-activate the neural developmental program.

scientific article published in August 2012

Identification and characterization of a novel splice site mutation in the SERPING1 gene in a family with hereditary angioedema.

scientific article published on 4 December 2013

Identification and characterization of the novel point mutation m.3634A>G in the mitochondrial MT-ND1 gene associated with LHON syndrome.

scientific article published on 7 September 2016

Investigation of shape variations in the antibody binding site by molecular dynamics computer simulation

scientific article published on 01 March 1994

Involvement of chromatin and histone deacetylation in SV40 T antigen transcription regulation.

scientific article published on 6 March 2007

Molecular damage in Fabry disease: characterization and prediction of alpha-galactosidase A pathological mutations

scientific article published on 18 November 2014

Molecular dynamics study of naturally existing cavity couplings in proteins

scientific article published on 27 March 2015

Novel Mutations Causing C5 Deficiency in Three North-African Families.

scientific article

PMUT: a web-based tool for the annotation of pathological mutations on proteins.

scientific article published on 6 May 2005

Partition of protein solvation into group contributions from molecular dynamics simulations.

scientific article

Preservation of protein clefts in comparative models.

scientific article

PupasView: a visual tool for selecting suitable SNPs, with putative pathological effect in genes, for genotyping purposes

scientific article

Representation of noncovalent interactions in protein structures.

scientific article published in June 1992

Scoring by Intermolecular Pairwise Propensities of Exposed Residues (SIPPER): A New Efficient Potential for Protein−Protein Docking

scientific article published on 07 January 2011

Sequence-based prediction of pathological mutations

scientific article published on 01 December 2004

The (in)dependence of alternative splicing and gene duplication

scientific article

The Complementarity Between Protein-Specific and General Pathogenicity Predictors for Amino Acid Substitutions

scientific article published on 10 July 2016

The SV40 T antigen modulates CBP histone acetyltransferase activity

scientific article

The functional modulation of epigenetic regulators by alternative splicing

scientific article

The relationship between gene isoform multiplicity, number of exons and protein divergence

scientific article

Toward predicting protein topology: an approach to identifying beta hairpins.

scientific article

Triplex-forming oligonucleotide target sequences in the human genome.

scientific article published on 15 January 2004

Use of bioinformatics tools for the annotation of disease-associated mutations in animal models

scientific article published on 01 December 2005

Use of surface area computations to describe atom-atom interactions.

scientific article

List of works by Xavier De la Cruz

A fast method for the determination of fractional contributions to solvation in proteins.

A new procedure for constructing peptides into a given Calpha chain.

A procedure for identifying homologous alternative splicing events

Alternative splicing mechanisms for the modulation of protein function: conservation between human and other species.

Alternative splicing of transcription factors' genes: beyond the increase of proteome diversity

An atomistic view to the gas phase proteome

Assessment of blind predictions of the clinical significance of BRCA1 and BRCA2 variants

Autoacetylation regulates P/CAF nuclear localization.

BRCA1- and BRCA2-specific in silico tools for variant interpretation in the CAGI 5 ENIGMA challenge

Cerebrospinal fluid-derived circulating tumour DNA better represents the genomic alterations of brain tumours than plasma.

Characterization of disease-associated single amino acid polymorphisms in terms of sequence and structure properties.

Characterization of structural variability sheds light on the specificity determinants of the interaction between effector domains and histone tails

Classical molecular interaction potentials: improved setup procedure in molecular dynamics simulations of proteins.

Clinical and structural impact of mutations affecting the residue Phe367 of FOXP3 in patients with IPEX syndrome.

Compensated pathogenic variants in coagulation factors VIII and IX present complex mapping between molecular impact and hemophilia severity

Data Mining of Molecular Dynamic Trajectories of Nucleic Acids

Discrete representations of the protein C alpha chain

EZH2 regulates neuroepithelium structure and neuroblast proliferation by repressing p21.

Exploring the Essential Dynamics of B-DNA

Genome-wide analysis reveals that Smad3 and JMJD3 HDM co-activate the neural developmental program.

Identification and characterization of a novel splice site mutation in the SERPING1 gene in a family with hereditary angioedema.

Identification and characterization of the novel point mutation m.3634A>G in the mitochondrial MT-ND1 gene associated with LHON syndrome.

Investigation of shape variations in the antibody binding site by molecular dynamics computer simulation

Involvement of chromatin and histone deacetylation in SV40 T antigen transcription regulation.

Molecular damage in Fabry disease: characterization and prediction of alpha-galactosidase A pathological mutations

Molecular dynamics study of naturally existing cavity couplings in proteins

Novel Mutations Causing C5 Deficiency in Three North-African Families.

PMUT: a web-based tool for the annotation of pathological mutations on proteins.

Partition of protein solvation into group contributions from molecular dynamics simulations.

Preservation of protein clefts in comparative models.

PupasView: a visual tool for selecting suitable SNPs, with putative pathological effect in genes, for genotyping purposes

Representation of noncovalent interactions in protein structures.

Scoring by Intermolecular Pairwise Propensities of Exposed Residues (SIPPER): A New Efficient Potential for Protein−Protein Docking

Sequence-based prediction of pathological mutations

The (in)dependence of alternative splicing and gene duplication

The Complementarity Between Protein-Specific and General Pathogenicity Predictors for Amino Acid Substitutions

The SV40 T antigen modulates CBP histone acetyltransferase activity

The functional modulation of epigenetic regulators by alternative splicing

The relationship between gene isoform multiplicity, number of exons and protein divergence

Toward predicting protein topology: an approach to identifying beta hairpins.

Triplex-forming oligonucleotide target sequences in the human genome.

Use of bioinformatics tools for the annotation of disease-associated mutations in animal models

Use of surface area computations to describe atom-atom interactions.