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List of works by Camille Locht

A common vaccination strategy to solve unsolved problems of tuberculosis and pertussis?

scientific article published on 10 July 2008

A phase I clinical study of a live attenuated Bordetella pertussis vaccine--BPZE1; a single centre, double-blind, placebo-controlled, dose-escalating study of BPZE1 given intranasally to healthy adult male volunteers

scientific article published on 8 January 2014

Added Value of Long-Term Cytokine Release Assays to Detect Mycobacterium tuberculosis Infection in HIV-Infected Subjects in Uganda

scientific article published on July 2016

Added value of long-term cytokine release assays to detect M. tuberculosis infection in HIV-infected subjects in Uganda

scientific article published on 3 March 2016

Age-Stratified T Cell Responses in Children Infected with Mycobacterium tuberculosis

scientific article published on 5 September 2017

Antibody response in pulmonary tuberculosis against recombinant 27kDa (MPT51, Rv3803c) protein of Mycobacterium tuberculosis.

scientific article published in January 2007

Assessing the reactogenicity of Tdap vaccine administered during pregnancy and antibodies to Bordetella pertussis antigens in maternal and cord sera of Thai women

scientific article published on 6 February 2018

Assessment of an optimized mycobacterial interspersed repetitive- unit-variable-number tandem-repeat typing system combined with spoligotyping for population-based molecular epidemiology studies of tuberculosis

scientific article published on 27 December 2006

Attenuated Bordetella pertussis protects against highly pathogenic influenza A viruses by dampening the cytokine storm

scientific article

Attenuated Bordetella pertussis vaccine candidate BPZE1 promotes human dendritic cell CCL21-induced migration and drives a Th1/Th17 response

scientific article published on 23 March 2011

Attenuated Bordetella pertussis vaccine protects against respiratory syncytial virus disease via an IL-17-dependent mechanism

scientific article published on January 2014

Attenuated Bordetella pertussis: new live vaccines for intranasal immunisation

scientific article published on 01 April 2006

B-cell responses after intranasal vaccination with the novel attenuated Bordetella pertussis vaccine strain BPZE1 in a randomized phase I clinical trial

scientific article published on 29 April 2014

BCG and protection against inflammatory and auto-immune diseases

scientific article published on 22 May 2017

Boosting BCG to protect against TB.

scientific article published on June 2010

Boosting with mycobacterial heparin-binding haemagglutinin enhances protection of Mycobacterium bovis BCG-vaccinated newborn mice against M. tuberculosis

scientific article published on 4 May 2010

Bordetella pertussis Infection in 2-Month-Old Infants Promotes Type 1 T Cell Responses

article

Bordetella pertussis from functional genomics to intranasal vaccination

scientific article published on April 2004

Bordetella pertussis pertactin knock-out strains reveal immunomodulatory properties of this virulence factor

scientific article published on 21 March 2018

Bordetella protein toxins

Both CD4⁺ and CD8⁺ lymphocytes participate in the IFN-γ response to filamentous hemagglutinin from Bordetella pertussis in infants, children, and adults

scientific article

Broad heparin-binding haemagglutinin-specific cytokine and chemokine response in infants following Mycobacterium bovis BCG vaccination

scientific article published on August 2012

Cellular immune responses of preterm infants after vaccination with whole-cell or acellular pertussis vaccines

scientific article published on 16 December 2009

Channel properties of TpsB transporter FhaC point to two functional domains with a C-terminal protein-conducting pore

scientific article

Characterization of a Bvg-regulated fatty acid methyl-transferase in Bordetella pertussis

scientific article

Chips from chips: application to the study of antibody responses to methylated proteins

scientific article

Cloning, expression, and purification of the 27 kDa (MPT51, Rv3803c) protein of Mycobacterium tuberculosis

scientific article published in July 2004

Coiled-Coil Antagonism Regulates Activity of Venus Flytrap-Domain-Containing Sensor Kinases of the BvgS Family

scientific article published on 27 February 2018

Combined RNAseq and ChIPseq Analyses of the BvgA Virulence Regulator of Bordetella pertussis

scientific article published on 19 May 2020

Comparison of the immune responses induced by local immunizations with recombinant Lactobacillus plantarum producing tetanus toxin fragment C in different cellular locations

scientific article published on 01 March 2002

Conformational Changes of an Interdomain Linker Mediate Mechanical Signal Transmission in Sensor Kinase BvgS.

scientific article

Conformational dynamics of protein transporter FhaC: large-scale motions of plug helix

scientific article

Construction and evaluation of Bordetella pertussis live attenuated vaccine strain BPZE1 producing Fim3.

scientific article published on 9 February 2018

Contribution of a heparin-binding haemagglutinin interferon-gamma release assay to the detection of Mycobacterium tuberculosis infection in HIV-infected patients: comparison with the tuberculin skin test and the QuantiFERON-TB Gold In-tube

scientific article

Correction: Molecular Evolution of the Two-Component System BvgAS Involved in Virulence Regulation in Bordetella

scientific article published in PLoS ONE

Crystal structure of Bordetella pertussis BugD solute receptor unveils the basis of ligand binding in a new family of periplasmic binding proteins

scientific article

Crystal structures of two Bordetella pertussis periplasmic receptors contribute to defining a novel pyroglutamic acid binding DctP subfamily

scientific article

Different T cell memory in preadolescents after whole-cell or acellular pertussis vaccination

scientific article published on 29 October 2013

Differential T and B cell responses against Mycobacterium tuberculosis heparin-binding hemagglutinin adhesin in infected healthy individuals and patients with tuberculosis

scientific article published on 31 January 2002

Differential contribution of the repeats to heparin binding of HBHA, a major adhesin of Mycobacterium tuberculosis

scientific article

Discovery of novel N-phenylphenoxyacetamide derivatives as EthR inhibitors and ethionamide boosters by combining high-throughput screening and synthesis

scientific article

Diversion of complement-mediated killing by Bordetella

scientific article published on 14 February 2018

Dose response of attenuated Bordetella pertussis BPZE1-induced protection in mice

scientific article

Dual mechanism of protection by live attenuated Bordetella pertussis BPZE1 against Bordetella bronchiseptica in mice

scientific article published on 17 July 2012

Dynamic interplay of membrane-proximal POTRA domain and conserved loop L6 in Omp85 transporter FhaC.

scientific article

Effector functions of heparin-binding hemagglutinin-specific CD8+ T lymphocytes in latent human tuberculosis

scientific article published on 9 June 2005

Eighty-kilodalton N-terminal moiety of Bordetella pertussis filamentous hemagglutinin: adherence, immunogenicity, and protective role

scientific article published on August 2002

Enhanced bacterial virulence through exploitation of host glycosaminoglycans

scientific article

Enzymatic methylation of the Mycobacterium tuberculosis heparin-binding haemagglutinin.

scientific article published in March 2007

Erratum for Carbonetti et al., "Highlights of the 11th International Bordetella Symposium: from Basic Biology to Vaccine Development".

scientific article

EthR, a repressor of the TetR/CamR family implicated in ethionamide resistance in mycobacteria, octamerizes cooperatively on its operator

scientific journal article

Ethionamide boosters. 2. Combining bioisosteric replacement and structure-based drug design to solve pharmacokinetic issues in a series of potent 1,2,4-oxadiazole EthR inhibitors

scientific article

Ethionamide boosters: synthesis, biological activity, and structure-activity relationships of a series of 1,2,4-oxadiazole EthR inhibitors

scientific article published on April 2011

Exploring drug target flexibility using in situ click chemistry: application to a mycobacterial transcriptional regulator

scientific article

Functional importance of a conserved sequence motif in FhaC, a prototypic member of the TpsB/Omp85 superfamily

scientific article

Genetic diversity and population structure of Mycobacterium tuberculosis in Casablanca, a Moroccan city with high incidence of tuberculosis

scientific article published on January 2004

Genetic stability of the live attenuated Bordetella pertussis vaccine candidate BPZE1.

scientific article

Genomic analysis of smooth tubercle bacilli provides insights into ancestry and pathoadaptation of Mycobacterium tuberculosis

scientific article published on 06 January 2013

Genomic island excisions in Bordetella petrii

scientific article published on 18 July 2009

Genotypic and phenotypic heterogeneity among Mycobacterium tuberculosis isolates from pulmonary tuberculosis patients

scientific article published on December 2004

Genotyping of the Mycobacterium tuberculosis complex using MIRUs: association with VNTR and spoligotyping for molecular epidemiology and evolutionary genetics.

scientific article published in July 2003

Good old BCG - what a century-old vaccine can contribute to modern medicine

scientific article published on 01 December 2020

HBHA vaccination may require both Th1 and Th17 immune responses to protect mice against tuberculosis

scientific article published on 22 September 2014

Heparin-binding haemagglutinin, a new tool for the detection of latent Mycobacterium tuberculosis infection in hemodialysis patients

scientific article

Heparin-binding-hemagglutinin-induced IFN-gamma release as a diagnostic tool for latent tuberculosis

scientific article

Heterologous prime-boost immunization with live attenuated B. pertussis BPZE1 followed by acellular pertussis vaccine in mice

scientific article published on 17 June 2014

Highlights of the 11th International Bordetella Symposium: from Basic Biology to Vaccine Development

scientific article

Highly attenuated Bordetella pertussis strain BPZE1 as a potential live vehicle for delivery of heterologous vaccine candidates

scientific article

How a different look at latency can help to develop novel diagnostics and vaccines against tuberculosis

scientific article published on November 2007

Human dendritic cell maturation and cytokine secretion upon stimulation with Bordetella pertussis filamentous haemagglutinin

scientific article published on 05 May 2014

Human isotype-dependent inhibitory antibody responses against Mycobacterium tuberculosis

scientific article

Identification and structural characterization of an unusual mycobacterial monomeromycolyl-diacylglycerol

scientific article published in August 2005

Immune response induced by recombinant Mycobacterium bovis BCG producing the cholera toxin B subunit.

scientific article

Immunogenicity and protective efficacy of neonatal vaccination against Bordetella pertussis in a murine model: evidence for early control of pertussis

scientific article

Immunogenicity of live attenuated B. pertussis BPZE1 producing the universal influenza vaccine candidate M2e.

scientific article

Immunoregulatory functions of interleukin 18 and its role in defense against bacterial pathogens

scientific article (publication date: March 2002)

Impact of HIV Infection on the Recurrence of Tuberculosis in South India

scientific article published in March 2010

In situ chemical modification of peptide microarrays: application to the study of the antibody responses to methylated antigens

scientific article

In vitro expansion of CD4+CD25highFOXP3+CD127low/- regulatory T cells from peripheral blood lymphocytes of healthy Mycobacterium tuberculosis-infected humans

scientific article published on 30 June 2007

In vivo imaging of bacterial colonization of the lower respiratory tract in a baboon model of Bordetella pertussis infection and transmission

scientific article published in Scientific Reports

In vivo interaction between the polyprenol phosphate mannose synthase Ppm1 and the integral membrane protein Ppm2 from Mycobacterium smegmatis revealed by a bacterial two-hybrid system

scientific article published on 8 November 2002

Inhibition of InhA activity, but not KasA activity, induces formation of a KasA-containing complex in mycobacteria

scientific article published on 24 March 2003

Integrating knowledge of Mycobacterium tuberculosis pathogenesis for the design of better vaccines

scientific article

Interaction of human Tamm-Horsfall glycoprotein with Bordetella pertussis toxin

scientific article (publication date: April 2002)

Interaction of the mycobacterial heparin-binding hemagglutinin with actin, as evidenced by single-molecule force spectroscopy

scientific article

Intracellular autoregulation of the Mycobacterium tuberculosis PrrA response regulator

article

Investigating pertussis toxin and its impact on vaccination

scientific article

Key role of effector memory CD4+ T lymphocytes in a short-incubation heparin-binding hemagglutinin gamma interferon release assay for the detection of latent tuberculosis

scientific article published on 03 January 2014

Linkage disequilibrium between minisatellite loci supports clonal evolution of Mycobacterium tuberculosis in a high tuberculosis incidence area

scientific article published in January 2003

Lipomannan and lipoarabinomannan from a clinical isolate of Mycobacterium kansasii: novel structural features and apoptosis-inducing properties

scientific article (publication date: 19 September 2003)

Live Attenuated Pertussis Vaccine BPZE1 Protects Baboons Against Bordetella pertussis Disease and Infection

scientific article published on 23 May 2017

Live attenuated B. pertussis BPZE1 rescues the immune functions of Respiratory Syncytial virus infected human dendritic cells by promoting Th1/Th17 responses

scientific article

Live attenuated B. pertussis as a single-dose nasal vaccine against whooping cough

scientific article

Live attenuated vaccines against pertussis

scientific article published on August 2014

Long-term immunity against pertussis induced by a single nasal administration of live attenuated B. pertussis BPZE1.

scientific article published on 13 August 2010

LppM impact on the colonization of macrophages by Mycobacterium tuberculosis

scientific article published on 24 May 2016

Macrophage-specific Mycobacterium tuberculosis genes: identification by green fluorescent protein and kanamycin resistance selection

scientific article

Membrane targeting of a bacterial virulence factor harbouring an extended signal peptide.

scientific article

Membrane-associated DegP in Bordetella chaperones a repeat-rich secretory protein

scientific article published on 12 May 2011

Methylation-dependent T cell immunity to Mycobacterium tuberculosis heparin-binding hemagglutinin

scientific article published on 08 August 2004

Molecular evolution of the two-component system BvgAS involved in virulence regulation in Bordetella

scientific article published on 14 September 2009

Molecular typing of Mycobacterium tuberculosis by mycobacterial interspersed repetitive unit-variable-number tandem repeat analysis, a more accurate method for identifying epidemiological links between patients with tuberculosis

scientific article

Multilocus variable-number tandem repeat typing of Mycobacterium ulcerans

scientific article

Mycobacterial heparin-binding hemagglutinin and laminin-binding protein share antigenic methyllysines that confer resistance to proteolysis

scientific article

Mycobacterium bovis BCG mycobacteria--new application

scientific article published on 01 January 2006

Mycobacterium bovis BCG producing interleukin-18 increases antigen-specific gamma interferon production in mice.

scientific article

Mycobacterium smegmatis produces an HBHA homologue which is not involved in epithelial adherence

scientific article published on 12 December 2006

Mycobacterium tuberculosis heparin-binding haemagglutinin adhesin (HBHA) triggers receptor-mediated transcytosis without altering the integrity of tight junctions

scientific journal article

Mycobacterium tuberculosis with disruption in genes encoding the phosphate binding proteins PstS1 and PstS2 is deficient in phosphate uptake and demonstrates reduced in vivo virulence

scientific journal article

Mycolic acid biosynthesis and enzymic characterization of the beta-ketoacyl-ACP synthase A-condensing enzyme from Mycobacterium tuberculosis

scientific journal article

Nanoscale mapping and functional analysis of individual adhesins on living bacteria

article

New pertussis vaccination approaches: en route to protect newborns? ⬇️

scientific article published on June 13, 2012

Non-specific Effects of Live Attenuated Pertussis Vaccine Against Heterologous Infectious and Inflammatory Diseases

article by Stéphane Cauchi & Camille Locht published 7 December 2018 in Frontiers in Immunology

Novel feature of Mycobacterium avium subsp. paratuberculosis, highlighted by characterization of the heparin-binding hemagglutinin adhesin

scientific article published on 23 August 2013

Optimal kinetics for quantification of antigen-induced cytokines in human peripheral blood mononuclear cells by real-time PCR and by ELISA.

scientific article published in October 2003

Origin, spread and demography of the Mycobacterium tuberculosis complex

scientific article published in 2008

Overrepresentation of a gene family encoding extracytoplasmic solute receptors in Bordetella

scientific article

PERISCOPE: road towards effective control of pertussis

scientific article published on 28 November 2018

Persistence at one year of age of antigen-induced cellular immune responses in preterm infants vaccinated against whooping cough: comparison of three different vaccines and effect of a booster dose

scientific article published on 18 February 2013

Pertussis toxin improves immune responses to a combined pneumococcal antigen and leads to enhanced protection against Streptococcus pneumoniae

scientific article

Pertussis: Where did we go wrong and what can we do about it?

scientific article published on 6 May 2016

Pertussis: acellular, whole-cell, new vaccines, what to choose?

scientific article

Possible options for new pertussis vaccines

scientific article published on April 2014

Ppm1, a novel polyprenol monophosphomannose synthase from Mycobacterium tuberculosis

scientific journal article

Predominance of ancestral lineages of Mycobacterium tuberculosis in India

scientific article published on September 2006

Production of nontypeable Haemophilus influenzae HtrA by recombinant Bordetella pertussis with the use of filamentous hemagglutinin as a carrier

scientific article published on July 2005

Proportions of interferon-γ-producing ascites lymphocytes in response to mycobacterial antigens: A help for early diagnosis of peritoneal tuberculosis in a low TB incidence country

Proposal for standardization of optimized mycobacterial interspersed repetitive unit-variable-number tandem repeat typing of Mycobacterium tuberculosis

scientific article

Protective role of adenylate cyclase in the context of a live pertussis vaccine candidate

scientific article published on 15 October 2013

Purification of native HBHA from Mycobacterium avium subsp. paratuberculosis

scientific article

Reciprocal interference of maternal and infant immunization in protection against pertussis

scientific article

Recombinant HBHA Boosting Effect on BCG-Induced Immunity against Mycobacterium tuberculosis Infection ⬇️

scientific article published on May 23, 2011

Regulation systems of toxin expression

Regulatory T cells depress immune responses to protective antigens in active tuberculosis

scientific article published on 31 May 2007

Risk stratification of latent tuberculosis defined by combined interferon gamma release assays

scientific article

Role of Bordetella bronchiseptica adenylate cyclase in nasal colonization and in development of local and systemic immune responses in piglets.

scientific article published in January 2005

Role of adhesin release for mucosal colonization by a bacterial pathogen

scientific article

Rv0613c/MSMEG_1285 Interacts with HBHA and Mediates Its Proper Cell-Surface Exposure in Mycobacteria

scientific article published in 2018

STAT3 Represses Nitric Oxide Synthesis in Human Macrophages upon Mycobacterium tuberculosis Infection

scientific article published on 7 July 2016

Selective intracellular accumulation of the major metabolite issued from the activation of the prodrug ethionamide in mycobacteria

scientific article published on 8 August 2006

Signal Transduction by BvgS Sensor Kinase: BINDING OF MODULATOR NICOTINATE AFFECTS THE CONFORMATION AND DYNAMICS OF THE ENTIRE PERIPLASMIC MOIETY.

scientific article published on 22 July 2015

Signal transduction by BvgS sensor kinase. Binding of modulator nicotinate affects the conformation and dynamics of the entire periplasmic moiety

scientific article published in October 2015

Single-molecule force spectroscopy of mycobacterial adhesin-adhesin interactions.

scientific article

Stability of variable-number tandem repeats of mycobacterial interspersed repetitive units from 12 loci in serial isolates of Mycobacterium tuberculosis

scientific article

Structural activation of the transcriptional repressor EthR from Mycobacterium tuberculosis by single amino acid change mimicking natural and synthetic ligands

scientific article

Structural analysis of Bordetella pertussis BugE solute receptor in a bound conformation

scientific article published on 18 October 2006

Structural study of lipomannan and lipoarabinomannan from Mycobacterium chelonae. Presence of unusual components with alpha 1,3-mannopyranose side chains

scientific article (publication date: 23 August 2002)

Structure of EthR in a ligand bound conformation reveals therapeutic perspectives against tuberculosis

scientific article published in October 2004

Structure of the membrane protein FhaC: a member of the Omp85-TpsB transporter superfamily.

scientific article

Substrate recognition by the POTRA domains of TpsB transporter FhaC.

scientific article

Surface anchoring of bacterial subtilisin important for maturation function.

scientific article

Synthetic EthR inhibitors boost antituberculous activity of ethionamide

scientific article

Systemic dissemination in tuberculosis and leprosy: do mycobacterial adhesins play a role?

scientific article

T- and B-cell-mediated protection induced by novel, live attenuated pertussis vaccine in mice. Cross protection against parapertussis

scientific article

Temperature-induced changes in the cell-wall components of Mycobacterium thermoresistibile

scientific article published in October 2002

Temporal analysis of French Bordetella pertussis isolates by comparative whole-genome hybridization

scientific article published on 06 June 2006

The Peptidyl–Prolyl Isomerase and Chaperone Par27 of Bordetella pertussis as the Prototype for a New Group of Parvulins

scientific article published on 09 November 2007

The Role of Mucosal Immunity in Pertussis

The crystal structure of filamentous hemagglutinin secretion domain and its implications for the two-partner secretion pathway

scholarly article

The forest behind the tree: phylogenetic exploration of a dominant Mycobacterium tuberculosis strain lineage from a high tuberculosis burden country

scientific article (publication date: 25 March 2011)

The ins and outs of pertussis toxin

scientific article published on 04 August 2011

The mycobacterial heparin-binding hemagglutinin is a protective antigen in the mouse aerosol challenge model of tuberculosis

scientific article published on December 2004

The periplasmic binding protein of a tripartite tricarboxylate transporter is involved in signal transduction.

scientific article published in August 2005

Toward Understanding the Essence of Post-Translational Modifications for the Mycobacterium tuberculosis Immunoproteome

scientific article

Transient requirement of the PrrA-PrrB two-component system for early intracellular multiplication of Mycobacterium tuberculosis

scientific journal article

Translocation path of a substrate protein through its Omp85 transporter

scientific article

Use of mycobacterial interspersed repetitive unit-variable-number tandem repeat typing to examine genetic diversity of Mycobacterium tuberculosis in Singapore

scientific article

Virulence regulation with Venus flytrap domains: structure and function of the periplasmic moiety of the sensor-kinase BvgS

scientific article

Will we have new pertussis vaccines?

scientific article published on 24 November 2017

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