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List of works by Jean Beggs

A Nuclear Export Block Triggers the Decay of Newly Synthesized Polyadenylated RNA

scientific article published on 01 August 2018

A complex pathway for 3' processing of the yeast U3 snoRNA.

scientific article published on December 2003

A fast and tuneable auxin-inducible degron for depletion of target proteins in budding yeast

scientific article published on 12 November 2018

A role for Q/N-rich aggregation-prone regions in P-body localization.

scientific article

A rule-based kinetic model of RNA polymerase II C-terminal domain phosphorylation ⬇️

scientific article published on June 26, 2013

A splicing-dependent transcriptional checkpoint associated with prespliceosome formation.

scientific article published on 20 February 2014

Analysis of Lsm1p and Lsm8p domains in the cellular localization of Lsm complexes in budding yeast.

scientific article published on 20 May 2009

Blocking late stages of splicing quickly limits pre-spliceosome assembly in vivo

scientific article published on 04 September 2019

Brr2p RNA helicase with a split personality: insights into structure and function

scientific article published on August 2010

Brr2p carboxy-terminal Sec63 domain modulates Prp16 splicing RNA helicase.

scientific article published on 26 November 2014

Brr2p-mediated conformational rearrangements in the spliceosome during activation and substrate repositioning

scientific article published in November 2012

Corrigendum: Transcription rate strongly affects splicing fidelity and cotranscriptionality in budding yeast.

scientific article published in April 2018

Cross-linking, ligation, and sequencing of hybrids reveals RNA-RNA interactions in yeast

scientific article

Cross-talk in transcription, splicing and chromatin: who makes the first call? ⬇️

scientific article published on October 1, 2010

Crosstalk between RNA metabolic pathways: an RNOMICS approach

scientific article

Cwc21p promotes the second step conformation of the spliceosome and modulates 3' splice site selection

scientific article

Extremely Rapid and Specific Metabolic Labelling of RNA In Vivo with 4-Thiouracil (Ers4tU)

scientific article published on 22 August 2019

Extremely fast and incredibly close: cotranscriptional splicing in budding yeast.

scientific article

Identification and characterization of Prp45p and Prp46p, essential pre-mRNA splicing factors

scientific article

Interaction between a G-patch protein and a spliceosomal DEXD/H-box ATPase that is critical for splicing

scientific article

Interaction of yeast eIF4G with spliceosome components: implications in pre-mRNA processing events.

scientific article published on 18 November 2009

Kinetic analysis of pre-ribosome structure in vivo.

scientific article published on 23 October 2012

Lsm Proteins are required for normal processing and stability of ribosomal RNAs

scientific article (publication date: 24 January 2003)

Lsm proteins are required for normal processing of pre-tRNAs and their efficient association with La-homologous protein Lhp1p

scientific article

Lsm proteins promote regeneration of pre-mRNA splicing activity

scientific article published in August 2004

Mechanism for Aar2p function as a U5 snRNP assembly factor

scientific article

Modelling Reveals Kinetic Advantages of Co-Transcriptional Splicing ⬇️

scientific article published on October 13, 2011

Mutagenesis of Snu114 domain IV identifies a developmental role in meiotic splicing

scientific article published on 23 January 2019

Mutations in the U5 snRNA result in altered splicing of subsets of pre-mRNAs and reduced stability of Prp8.

scientific article published on 15 May 2009

Nuclear pre-mRNA decapping and 5' degradation in yeast require the Lsm2-8p complex.

scientific article published on November 2004

Physical and genetic interactions of yeast Cwc21p, an ortholog of human SRm300/SRRM2, suggest a role at the catalytic center of the spliceosome

scientific article published on 23 October 2009

Processivity and coupling in messenger RNA transcription

scientific article

Prognosis for splicing factor PRPF8 retinitis pigmentosa, novel mutations and correlation between human and yeast phenotypes

scientific article published in May 2010

Prp8 protein: at the heart of the spliceosome

scientific article

Prp8p dissection reveals domain structure and protein interaction sites

scientific article

RNA helicases in splicing ⬇️

scientific article published on December 10, 2012

RNA polymerase II stalling at pre-mRNA splice sites is enforced by ubiquitination of the catalytic subunit

scientific article published on 13 October 2017

Requirements for nuclear localization of the Lsm2-8p complex and competition between nuclear and cytoplasmic Lsm complexes

scientific article

Revisiting the window of opportunity for co-transcriptional splicing in budding yeast

scientific article published on 21 May 2020

RiboSys, a high-resolution, quantitative approach to measure the in vivo kinetics of pre-mRNA splicing and 3'-end processing in Saccharomyces cerevisiae.

scientific article

Splicing goes global

scientific article

Splicing-dependent RNA polymerase pausing in yeast ⬇️

scientific article published on November 24, 2010

Spt5 modulates cotranscriptional spliceosome assembly in Saccharomyces cerevisiae

scientific article published on 09 July 2019

Structural basis for dual roles of Aar2p in U5 snRNP assembly

scientific article

Structure, function and regulation of spliceosomal RNA helicases ⬇️

scientific article published on March 29, 2012

The Lsm2-8 complex determines nuclear localization of the spliceosomal U6 snRNA.

scientific article published on 23 January 2007

Transcription rate strongly affects splicing fidelity and cotranscriptionality in budding yeast.

scientific article published on 18 December 2017

Transcriptome-wide RNA processing kinetics revealed using extremely short 4tU labeling.

scientific article published on 17 December 2015

Tuning Degradation to Achieve Specific and Efficient Protein Depletion

scientific article published on 20 July 2019

Vac14 controls PtdIns(3,5)P(2) synthesis and Fab1-dependent protein trafficking to the multivesicular body

scientific article

Yeast ntr1/spp382 mediates prp43 function in postspliceosomes.

scientific article

prp8 mutations that cause human retinitis pigmentosa lead to a U5 snRNP maturation defect in yeast

scientific article

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